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Search Results: 1 - 10 of 204366 matches for " Adéla?de Hué "
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Modulation of Postprandial Glucose Bioavailability in a Cohort of Healthy and Pre-Diabetics Subjects during Ramadan Fasting in Côte d’Ivoire  [PDF]
Jacko R. Abodo, Jean B. Gbakayoro, Kouakou Brou, Georges G. Tiahou, Adélade Hué, Assita Yao, Jocelyne Danho, Adrien Lokrou
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2017, DOI: 10.4236/ojemd.2017.75012
Abstract: Objective: After the Ramadan fasting period, there is an increasing prevalence of diabetes in Cote d’Ivoire, in diabetes care centers. The objective of this study was to assess the consumption of sugary foods during this period and to determine the risks of diabetes in Muslim populations. Methods: Information was collected on the type and amount of sugary foods consumed. Methods for the preparation of these foods have been determined. Intake frequencies and postprandial glycemic responses were studied. The usual statistical methods were used. Results: Between 70% and 85% of the “fasters” consume plenty of these sugary foods during this period, with an average added sugar level varying between 10% and 35% and a daily consumption of between 250 cl and 0.5 l. The added sugar leads to hyperglycemia in both healthy subjects and pre diabetics. Conclusion: Regular consumption of these sugary foods results in significant hyperglycaemia throughout the month of fasting with a significantly higher blood glucose level in pre diabetic subjects. This makes pre diabetics people more at risk of diabetes among Muslim populations during Ramadan fasting.
Typology and Etiology of Precocious Puberty in Sub-Saharan Africa: Report of 8 Cases in Abidjan, Ivory Coast a  [PDF]
Jacko R. Abodo, Laurette Agbré-Yacé, Adélade Hué, Ténédia Soro-Coulibaly, Micondo Kouamé, Mamadou Sanogo, Jocelyne Danho, Jean B. Ahoussi, Adrien Lokrou
Advances in Sexual Medicine (ASM) , 2017, DOI: 10.4236/asm.2017.74013
Abstract: Introduction: Early puberty is defined by development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. In the West, one in five children out of 100,000 is concerned. Little information on sub-Saharan African patients exists concerning this pathology. Objective: To determine the etiology and clinical characteristics of early puberty in a cohort of Ivorian children. Methods: We conducted a cross-sectional study between 2015 and 2017 in children admitted to early puberty in the unique Endocrinology Service of the country. The epidemiology and clinical characteristics were assessed. Results: The eight patients involved were all females. Their mean age at diagnosis was 7 years and 3 months and the mean age of first symptoms begun at 5 years and 6 months. Seven patients had a central precocious puberty (CPP) including five cases of idiopathic CPP (ICPP) treated by (GnRH agonist) and two cases with secondary precocious puberty (SPP). One of them has a hypothalamic hamartoma and the other a sequelae of encephalopathy. The last case had a peripheral precocious puberty (PPP) causes by ovarian dystrophy. Conclusion: Our results confirm the predominance of idiopathic central precocious puberty particularly in girls.
Prolonged Visual Experience in Adulthood Modulates Holistic Face Perception
Adélade de Heering, Bruno Rossion
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002317
Abstract: Background Using the well-known composite illusion as a marker of the holistic perception of faces, we tested how prolonged visual experience with a specific population of faces (4- to 6-year-old children) modulates the face perception system in adulthood. Methodology/Principal Findings We report a face composite effect that is larger for adult than children faces in a group of adults without experience with children faces (“children-face novices”), while it is of equal magnitude for adults and children faces in a population of preschool teachers (“children-face experts”). When considering preschool teachers only, we observed a significant correlation between the number of years of experience with children faces and the differential face composite effect between children and adults faces. Participants with at least 10 years of qualitative experience with children faces had a larger composite face effect for children than adult faces. Conclusions/Significance Overall, these observations indicate that even in adulthood face processes can be reshaped qualitatively, presumably to facilitate efficient processing of the differential morphological features of the frequently encountered population of faces.
Réaction sociale de l’opinion publique face aux prestations de soins au CHU de Treichville (Abidjan) / The social reaction of public opinion towards CHU health services in Treichville (Abidjan)
Gakoué Adélade,Koudou Opadou
Rivista di Criminologia, Vittimologia e Sicurezza , 2013,
Abstract: Lo studio della reazione sociale nei confronti delle prestazioni sanitarie è quasi inesistente in Costa d’Avorio. L’obiettivo della presente ricerca era di raccogliere conoscenze e giudizi di valore costruiti dagli individui attorno alla situazione di presa in carico dei malati al CHU (Centro Ospedaliero Universitario) di Treichville. La ricerca è stata realizzata tramite interviste semi-strutturate rivolte a cento persone. In generale, si sono rilevate impressioni relativamente positive in merito alle prestazioni sanitarie. In effetti, attitudini, opinioni e comportamenti in maggioranza positivi si sono tradotti in opinioni favorevoli, adesione e accettazione delle prestazioni. Tuttavia, queste attitudini non hanno portato sempre direttamente le persone al CHU in caso di malattia, ma soltanto per necessità estrema in rapporto allo stato di salute. Ciò nonostante, dato che le denunce e le lamentele registrate non sono in numero trascurabile, vengono avanzate proposte operative al fine di migliorare le prestazioni. L’étude de la réaction sociale relative aux prestations de soins est quasi-inexistante en C te d’Ivoire. L’objectif de cette étude prospective était de cerner les connaissances et jugements de valeurs construites par les individus autour de la prise en charge des malades au CHU (Centre Hospitalier Universitaire) de Treichville. L’enquête interrogation s’est réalisée à l’aide d’un guide d’entretien auprès de cent individus. On notait globalement une appréciation relativement positive des prestations de soins. En effet, les attitudes, opinions et comportements de l’opinion publique en majorité positifs s’est traduit par des opinions favorables, des attitudes d’adhésion et d’acceptation des prestations. Mais, ces attitudes ne les conduit pas toujours directement au CHU dès qu’ils sont malades mais en cas de nécessité exigée par l’état de santé. Toutefois, les plaintes et découragements enregistrés n’étant pas négligeables, des propositions de mesures personnelles complétées à celles des enquêtés ont été faites en vue de l’amélioration des prestations.The study of the social reaction related to health services is quasi non-existent in Ivory Coast. The objective of this forward-looking study was to gather the knowledge and the judgments of values built by individuals regarding the care of the patients in the CHU (University Hospital Centre) of Treichville. The survey was conducted using an interview guide with one hundred people. Overall, there was a relatively positive assessment of care. Indeed, attitudes, opinions and for the greater part positi
The MMTV-PyVT Transgenic Mouse as a Multistage Model for Mammary Carcinoma and the Efficacy of Antineoplastic Treatment  [PDF]
Stephanie Shishido, Adélade Delahaye, Amanda Beck, Thu Annelise Nguyen
Journal of Cancer Therapy (JCT) , 2013, DOI: 10.4236/jct.2013.47138

Animal models are commonly used to analyze the mechanism of carcinogenesis as well as the development and screening of potent drugs. Although numerous animal models of breast cancer have been used in research, few display multiple stages of tumorigenesis. The transgenic strain FVB/N-Tg(MMTV-PyVT) 634 Mul/J (also known as PyVT) was established to determine the effect of mammary gland-specific expression of the polyomavirus middle T antigen. Here the PyVT model with three distinct stages of tumor development (Pre, Early, and Late stages) was used as a model system for measuring tumor growth, tumor burden, and metastasis of mammary carcinomas. Additionally the expression profile of the molecular markers, survivin and Ki-67, was determined. Three antineoplastic compounds were tested over a 14-day period to determine their efficacy at attenuating tumor growth at each stage of development. Interestingly cisplatin and paclitaxel were determined to be ineffective anticancer drugs, while tamoxifen significantly reduced tumor growth in the Pre and Early stages of tumor formation.

Nonparametric estimation of the division rate of an age dependent branching process
Marc Hoffmann,Adélade Olivier
Statistics , 2014,
Abstract: We study the nonparametric estimation of the branching rate $B(x)$ of a supercritical Bellman-Harris population: a particle with age $x$ has a random lifetime governed by $B(x)$; at its death time, it gives rise to $k \geq 2$ children with lifetimes governed by the same division rate and so on. We observe in continuous time the process over $[0,T]$. Asymptotics are taken as $T \rightarrow \infty$; the data are stochastically dependent and one has to face simultaneously censoring, bias selection and non-ancillarity of the number of observations. In this setting, under appropriate ergodicity properties, we construct a kernel-based estimator of $B(x)$ that achieves the rate of convergence $\exp(-\lambda_B \frac{\beta}{2\beta+1}T)$, where $\lambda_B$ is the Malthus parameter and $\beta >0$ is the smoothness of the function $B(x)$ in a vicinity of $x$. We prove that this rate is optimal in a minimax sense and we relate it explicitly to classical nonparametric models such as density estimation observed on an appropriate (parameter dependent) scale. We also shed some light on the fact that estimation with kernel estimators based on data alive at time $T$ only is not sufficient to obtain optimal rates of convergence, a phenomenon which is specific to nonparametric estimation and that has been observed in other related growth-fragmentation models.
Dissemination of Cephalosporin Resistance Genes between Escherichia coli Strains from Farm Animals and Humans by Specific Plasmid Lineages
Mark de Been equal contributor ,Val F. Lanza equal contributor,María de Toro,Jelle Scharringa,Wietske Dohmen,Yu Du,Juan Hu,Ying Lei,Ning Li,Ave Tooming-Klunderud,Dick J. J. Heederik,Ad C. Fluit,Marc J. M. Bonten,Rob J. L. Willems,Fernando de la Cruz ,Willem van Schaik
PLOS Genetics , 2014, DOI: doi/10.1371/journal.pgen.1004776
Abstract: Third-generation cephalosporins are a class of β-lactam antibiotics that are often used for the treatment of human infections caused by Gram-negative bacteria, especially Escherichia coli. Worryingly, the incidence of human infections caused by third-generation cephalosporin-resistant E. coli is increasing worldwide. Recent studies have suggested that these E. coli strains, and their antibiotic resistance genes, can spread from food-producing animals, via the food-chain, to humans. However, these studies used traditional typing methods, which may not have provided sufficient resolution to reliably assess the relatedness of these strains. We therefore used whole-genome sequencing (WGS) to study the relatedness of cephalosporin-resistant E. coli from humans, chicken meat, poultry and pigs. One strain collection included pairs of human and poultry-associated strains that had previously been considered to be identical based on Multi-Locus Sequence Typing, plasmid typing and antibiotic resistance gene sequencing. The second collection included isolates from farmers and their pigs. WGS analysis revealed considerable heterogeneity between human and poultry-associated isolates. The most closely related pairs of strains from both sources carried 1263 Single-Nucleotide Polymorphisms (SNPs) per Mbp core genome. In contrast, epidemiologically linked strains from humans and pigs differed by only 1.8 SNPs per Mbp core genome. WGS-based plasmid reconstructions revealed three distinct plasmid lineages (IncI1- and IncK-type) that carried cephalosporin resistance genes of the Extended-Spectrum Beta-Lactamase (ESBL)- and AmpC-types. The plasmid backbones within each lineage were virtually identical and were shared by genetically unrelated human and animal isolates. Plasmid reconstructions from short-read sequencing data were validated by long-read DNA sequencing for two strains. Our findings failed to demonstrate evidence for recent clonal transmission of cephalosporin-resistant E. coli strains from poultry to humans, as has been suggested based on traditional, low-resolution typing methods. Instead, our data suggest that cephalosporin resistance genes are mainly disseminated in animals and humans via distinct plasmids.
Early Deafness Increases the Face Inversion Effect But Does Not Modulate the Composite Face Effect
Adélade de Heering,Bruno Rossion,Olivier Pascalis
Frontiers in Psychology , 2012, DOI: 10.3389/fpsyg.2012.00124
Abstract: Early deprivation in audition can have striking effects on the development of visual processing. Here we investigated whether early deafness induces changes in holistic/configural face processing. To this end, we compared the results of a group of early deaf participants to those of a group of hearing participants in an inversion-matching task (Experiment 1) and a composite face task (Experiment 2). We hypothesized that deaf individuals would show an enhanced inversion effect and/or an increased composite face effect compared to hearing controls in case of enhanced holistic/configural face processing. Conversely, these effects would be reduced if they rely more on facial features than hearing controls. As a result, we found that deaf individuals showed an increased inversion effect for faces, but not for non-face objects. They were also significantly slower than hearing controls to match inverted faces. However, the two populations did not differ regarding the overall size of their composite face effect. Altogether these results suggest that early deafness does not enhance or reduce the amount of holistic/configural processing devoted to faces but may increase the dependency on this mode of processing.
Autoregressive functions estimation in nonlinear bifurcating autoregressive models
Siméon Valère Bitseki Penda,Adélade Olivier
Statistics , 2015,
Abstract: Bifurcating autoregressive processes, which can be seen as an adaptation of au-toregressive processes for a binary tree structure, have been extensively studied during the last decade in a parametric context. In this work we do not specify any a priori form for the two autoregressive functions and we use nonparametric techniques. We investigate both nonasymp-totic and asymptotic behavior of the Nadaraya-Watson type estimators of the autoregressive functions. We build our estimators observing the process on a finite subtree denoted by Tn, up to the depth n. Estimators achieve the classical rate |Tn| --$\beta$/(2$\beta$+1) in quadratic loss over H{\"o}lder classes of smoothness. We prove almost sure convergence, asymptotic normality giving the bias expression when choosing the optimal bandwidth and a moderate deviations principle. Our proofs rely on specific techniques used to study bifurcating Markov chains. Finally, we address the question of asymmetry and develop an asymptotic test for the equality of the two autoregressive functions.
Adaptive estimation for bifurcating Markov chains
S. Valère Bitseki Penda,Marc Hoffmann,Adélade Olivier
Statistics , 2015,
Abstract: In a first part, we prove Bernstein-type deviation inequalities for bifurcating Markov chains (BMC) under a geometric ergodicity assumption, completing former results of Guyon and Bitseki Penda, Djellout and Guillin. These preliminary results are the key ingredient to implement nonparametric wavelet thresholding estimation procedures: in a second part, we construct nonparametric estimators of the transition density of a BMC, of its mean transition density and of the corresponding invariant density, and show smoothness adaptation over various multivariate Besov classes under $L^p$-loss error, for $1 \leq p < \infty$. We prove that our estimators are (nearly) optimal in a minimax sense. As an application, we obtain new results for the estimation of the splitting size-dependent rate of growth-fragmentation models and we extend the statistical study of bifurcating autoregressive processes.
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