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Search Results: 1 - 10 of 12 matches for " Abdugheni Kutluk "
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Evaluation of Hepatic Cystic Echinococcosis’ CT image in Xinjiang Uygur Autonomous Region based on Kolmogorov Complexity Model  [PDF]
Jingjing Zhou, Murat Hamit, Abdugheni Kutluk, Chuanbo Yan, Li Li, Jianjun Chen, Yanting Hu, Dewei Kong, Weikang Yuan
Engineering (ENG) , 2012, DOI: 10.4236/eng.2012.410B015

Designing and developing computer-assisted image processing techniques to help doctors improve their diagnosis has received considerable interests over the past years. In this paper, we used the kolmogorov complexity model to analyze the CT images of the healthy liver and multiple daughter hydatid cysts. Before the complexity characteristic calculating, the image preprocessing methods had been used for image standardization. From the kolmogorov complexity model, complexity characteristic were calculated in order to quantify the complexity, between healthy liver and multiple daughter hydatid cysts. Then we use statistical method to analyze the complexity characteristic of those two types of images. Our preliminary results show that the complexity characteristic has statistically significant (p<0.05) to analyze these two types CT images, between the healthy liver and the multiple daughter hydatid cysts. Furthermore, the result leads us to the conclusion that the kolmogorov complexity model could use for analyze the hydatid disease and will also extend the analysis the other lesions of liver.

An Early Warning Model with Technical Indicators: The Case of Ise (Istanbul Stock Exchange)  [PDF]
Kutluk Kagan Sumer
iBusiness (IB) , 2013, DOI: 10.4236/ib.2013.54022

In this study, the technical indicators are used in forecasting whether stock prices will rise, fall or will be constant at the following day. The indicators are generated by taking into account the daily stock returns. If the daily stock returns are positive, the indicator is coded as “+1”; if the daily stock returns are constant, the indicator is coded as “0” and at least if the daily stock returns are negative, the indicator is coded as “-1”. These indicator values express the dependent variable of ordered choice models which independent variables are technical indicators. The ordered choice models are applied to all of the stocks of ISE (Istanbul Stock Exchange).

The expression of cyclin-dependent kinase inhibitors p15, p16, p21, and p27 during ovarian follicle growth initiation in the mouse
Aykut Bayrak, Kutluk Oktay
Reproductive Biology and Endocrinology , 2003, DOI: 10.1186/1477-7827-1-41
Abstract: In this study we tested the expression of CDKIs p15, p16, p21 and p27 by immunohistochemistry to determine the role of CDKIs in the initiation of primordial follicle growth. Ovaries were collected from 60-day-old cycling B6D2F1/J mice (n = 16).Expression of p15, p16, p21 and p27 did not vary in granulosa and theca cells by the follicle stage. However, p16 staining was stronger (++) in the oocytes of all primordial, and 57.4 ± 3.1% of primary follicles compared to the remaining primary and more advanced follicles (+). Interestingly, primary follicles with weaker (+) oocyte staining for p16 had significantly larger mean follicle diameter compared to the primary and primordial follicles with stronger (++) oocyte staining (55.6 ± 2.1 vs. 32.0 ± 1.0 and 26.5 ± 0.7 μm, respectively, p < 0.0001). This difference in follicle diameter was mainly due to a larger mean oocyte diameter (primary follicles, stronger vs. weaker, 19.6 ± 0.6 vs. 31.5 ± 1.4 μm, p < 0.0001). Oocytes of atretic follicles showed stronger staining with all four CDKIs.These preliminary findings suggest that the initiation of oocyte growth, which seems to lead follicle growth, is associated with diminished p16 expression in the mouse ovary. Further studies are needed to investigate the factors that regulate the expression of p16 in the oocyte, which might also govern the initiation of primordial follicle growth.The onset of growth of an individual primordial follicle is unpredictable; some beginning shortly after formation while others may remain "quiescent" for many years. By which mechanism the primordial follicles are selected to grow is unknown. We previously showed that the Proliferating Cell Nuclear Antigen (PCNA) is expressed in the rodent ovarian follicles at the earliest sign of growth [1]. PCNA is a co-factor of cyclin-D and it makes a complex with cyclin-D, a cyclin dependent kinase (CDK), and a cyclin dependent kinase inhibitor (CDKI). The progression of cells through the cell cycle is regulated
Enhancement of Neoangiogenesis and Follicle Survival by Sphingosine-1-Phosphate in Human Ovarian Tissue Xenotransplants
Reza Soleimani,Elke Heytens,Kutluk Oktay
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0019475
Abstract: Ovarian transplantation is one of the key approaches to restoring fertility in women who became menopausal as a result of cancer treatments. A major limitation of human ovarian transplants is massive follicular loss during revascularization. Here we investigated whether sphingosine-1-phosphate or its receptor agonists could enhance neoangiogenesis and follicle survival in ovarian transplants in a xenograft model. Human ovarian tissue xenografts in severe-combined-immunodeficient mice were treated with sphingosine-1-phosphate, its analogs, or vehicle for 1–10 days. We found that sphingosine-1-phosphate treatment increased vascular density in ovarian transplants significantly whereas FTY720 and SEW2871 had the opposite effect. In addition, sphingosine-1-phosphate accelerated the angiogenic process compared to vehicle-treated controls. Furthermore, sphingosine-1-phosphate treatment was associated with a significant proliferation of ovarian stromal cell as well as reduced necrosis and tissue hypoxia compared to the vehicle-treated controls. This resulted in a significantly lower percentage of apoptotic follicles in sphingosine-1-phosphate-treated transplants. We conclude that while sphingosine-1-phosphate promotes neoangiogenesis in ovarian transplants and reduces ischemic reperfusion injury, sphingosine-1-phosphate receptor agonists appear to functionally antagonize this process. Sphingosine-1-phosphate holds great promise to clinically enhance the survival and longevity of human autologous ovarian transplants.
An Empirical Approach to Determine the Relationship Strength between Internet Media and Online Readership = nternet Medyas le Okur Aras ndaki li kiyi Saptamaya Y nelik G zleme Dayal Bir Yakla m
Kutluk ?ZGüVEN,Yasemin ATILGAN,Mitat UYSAL
Dogus University Journal , 2009,
Abstract: Web content in the context of online news is growing at a rapid speed where traditional news reading habits shift in favour of the Internet version. At the same time readership behaviour also changes from print paper readers to more selective online users, who expect news services follow general trends of the online media such as dynamic customised content and personalisation. In an environment where users are often reluctant to fill forms or reveal their preferences in news content, this entails that the online news Web site has to track the behaviour of the reader and serve the reader the content that fits his or her requirements. In this study online readership preferences are observed to produce personalised content, types of news articles that are more relevant to the reader’s preferred categories. The problem is then reduced to determining the strength of the relationship between the reader node and the news category nodes, at which a relationship metric is borrowed from Customer Relationship Management studies.
Effects of Soil Properties on the Occurrence of Beet Necrotic Yellow Vein Virus and Beet Soilborne Virus on Sugar Beet in Tokat, Turkey
Nazli Dide Kutluk Yilmaz,Yusuf Yanar,Hikmet Gunal,Semih Erkan
Plant Pathology Journal , 2004,
Abstract: Beet necrotic yellow vein virus (BNYVV) and Beet soilborne virus (BSBV) are the important soilborne virus diseases in the production areas of sugar beet. A survey was carried out to detect these viruses in soil samples using bait plant test and double antibody sandwich-enzyme-linked immunosorbent assay (DAS-ELISA) and triple antibody sandwich-ELISA (TAS-ELISA) in sugar beet production areas in Tokat, Turkey in 2001. Of the 26 soil samples taken from 8 districts in Tokat province, it was found that 23 samples (85.5%) were infected with BNYVV and 24 samples (92.3%) with BSBV. In 2002, total 49 root samples were tested for the presence of these viruses by ELISA. The incidence of BNYVV (67%) was greater than that of BSBV (8%). Furthermore, in this study it was determined the relationships between physical and chemical properties of soils and the appearance of BNYVV and BSBV. But, it could not determine any connection between infectious potential of viruses and soil properties.
Do we really need to panic in all anisocoria cases in critical care?
Yalcin Saban,Pampal Kutluk,Erden Aydin,Oba Sirali
Indian Journal of Anaesthesia , 2010,
An Evaluation of Pre-Admission Factors Affecting the Admission Time of Patients with Stroke Symptoms
Tanzer KORKMAZ,Gurkan ERSOY,Kursad KUTLUK,Bulent ERBIL
Turkish Journal of Emergency Medicine , 2010,
Abstract: Objective: New drugs to be optimally curative in stroke therapy should be given quickly after the appearence of the symptoms. In this study, we studied the factors regarding the delay of the patients’ admissions to the emergency departments and the knowledge level of the people about the stroke. Methods: A prospective study was designed in a third referral hospital. The adult patients admitting to hospital with neurologic symptoms were recruited in the study. The patients who admit to the hospital in more than 3 hours after the symptoms appear were asked about the reasons of the delay with open ended questions. Results: The mean age of 117 patients that included in the study were 66.7±13.2. Of these patients, 44% (n=52) were admitted in the first three hours. For patients arriving at hospital in the first three hours the demographic analysis were statistically significant for those living with family members (p=0,008) and for those with speech impairment (p=0,002). Of the patients who arrived at the hospital in more than three hours (n=61, 45.9%), most had either waited for the symptoms to disappear or were hesitant about coming to the hospital. Conclusions: The general knowledge level of the people about the symptoms and risk factors of stroke is thought to be the most important parameter concerning the early admittance. However in this study we found that even the knowledge level is insufficient stroke patients have been reported to admit to the emergency department in the first six hours.
Niemann - Pick disease associated with hemophagocytic syndrome
Serap Karaman,Nafiye Urganc?,Günsel Kutluk,Feyzullah ?etinkaya
Turkish Journal of Hematology , 2010,
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a disease characterized by phagocytosis of blood cells by macrophages within the lymphoreticular tissue. It can develop secondary to some diseases or be familial as a result of genetic mutations. Niemann-Pick disease (NPD) is a very rare lipid storage disease. A three-month-old girl presented with high fever (39°C), abdominal distension and paleness. The parents were consanguineous. The liver and spleen were palpable 10 cm and 11 cm below the costal margins, respectively. Bicytopenia (Hb: 5.5 g/dl, platelet: 77000/mm3), hypertriglyceridemia (351 mg/dl), hyperferritinemia (>1500 ng/dl) and hypofibrinogenemia (120 mg/dl) were detected. Bone marrow aspiration demonstrated foam cells and hemophagocytosis by macrophages and Niemann-Pick cells. Lysosomal sphingomyelinase activity was 0.24 nmol/h/mg/protein (normal: 0.86-2.8). Due to the parents’ refusal of further evaluation, the nature of HLH as primary or secondary could not be determined. To the best of our knowledge, this is the first case of NPD associated with HLH and the first demonstration of hemophagocytosis by Niemann-Pick cells.
Lacunar Infarction Associated With Intracranial Venous Hypertension
Yeliz PEKCEVIK,Suleyman MEN,Egemen IDIMAN,Kursat KUTLUK
Journal of Neurological Sciences , 2008,
Abstract: Lacunar infarcts constitute a subtype of stroke with a diameter of less than 15 mm manifested by the presence of lacunar syndromes. The ischemic lesion in lacunar infarcts may often be caused by occlusion of a single, small perforating artery. However it is known that lacunar infarcts may also be associated with large artery disease, cardioembolism, and other less frequently encountered causes including antiphospholipidic syndrome, amyloid angiopathy, infectious arteritis, and inflammatory arteritis. A lacunar infarct of venous type is unusual. A 72-year-old woman presented with left hemiparesis that developed within the last several hours. She also had mild dementia for several months. Radiological examination showed a white matter lacunar infarct evidenced by restricted diffusion and T2 abnormality and dural arteriovenous fistula of the superior sagittal sinus. Because the segment distal to the fistula was occluded the fistulous flow was drained away from the sinus via retrograde flow through the cortical veins, which leaded to intracranial venous hypertension. The findings in our patient suggest that venous causes should also be considered in the differential diagnosis of lacunar infarcts.
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