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Search Results: 1 - 2 of 2 matches for " Abdrahim Kribii "
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Evaluation of Acute Toxicity and Sedative Effects of Ethylic Extract of Thymelaea lythroides in Wistar Rats  [PDF]
Inssaf Berkiks, Abdelhalem Mesfioui, Abdrahim Kribii, Ali Ouichou, Bouchra Benazzouz, Aboubaker El Hessni
Journal of Behavioral and Brain Science (JBBS) , 2014, DOI: 10.4236/jbbs.2014.43016
Abstract: The purpose of this study was to evaluate the acute toxicity and sedative effect of the ethylic extract of Thymelaea lythroides (Tl) on Wistar rats. The study was based on the gavage administration of the ethylic extract of Tl with different doses (i.e. 200, 400, 500 and 5000 mg/kg), where the toxicity and the sedative activity of the plant were observed and the obtained results were analyzed using the ANOVA test followed by the Bonferroni test. The main results of this study showed that the lethal dose of the ethylic extract of Tl was higher than the 5000 mg/kg dose. Moreover, when compared to the control rats, the animals treated with 5000 mg/kg of the extract exhibited significant reduction in appetite for food and water in the first week. Furthermore, results of the psychotropic test conducted during this study showed visible effects on the exploratory activity of the rats. The dose of 5000 mg/kg was also found to have a significant central nervous system effect; the locomotor activities of the animals decreased in a manner similar to those administered with Zepam as control.
A Rare Localization of Ectopic Pregnancy: Intramyometrial Pregnancy in Twin Pregnancy following IVF
Lahcen Boukhanni,Yassir Ait Benkaddour,Ahlam Bassir,Abdrahim Aboulfalah,Hamid Asmouki,Abderraouf Soummani
Case Reports in Obstetrics and Gynecology , 2014, DOI: 10.1155/2014/893935
Abstract: Intramyometrial pregnancy is a rare form of ectopic pregnancy. It makes a diagnostic and therapeutic challenge. If misdiagnosed the intramyometrial pregnancy can cause a uterine rupture and become life-threatening condition. We report a case of intramyometrial pregnancy in twin pregnancy following IVF with spontaneous abortion of the first twin At 9 weeks of gestation. The 10 weeks scan showed a normal fetus which was described to be highly localized in the uterus but the diagnosis of intramyometrial pregnancy was not suspected. The patient was admitted at 14 weeks of gestation with pelvic pain, hemorrhage, and shock. She was operated and the diagnosis of ruptured intramyometrial pregnancy was done and managed conservatively. This case illustrates the diagnostic difficulties of intramyometrial pregnancy. We discuss pathophysiology, diagnosis, and treatment of this exceptional form of ectopic pregnancy. 1. Introduction Intramyometrial pregnancy is the rarest subtype of ectopic pregnancy. The first case of intramural pregnancy was reported in 1924. Preoperative diagnosis is difficult and hysterectomy is always required because of delayed diagnosis. 2. Case Report We report a case of intramyometrial pregnancy in twin pregnancy following IVF. The 32-year-old patient had a history of 4 years of unexplained infertility with 3 implantation failures following IVF. She became pregnant of a twin after an IFV-ET of 2 embryos in our department. The embryo transfer was easy and without touching the uterine wall. A spontaneous abortion of the first twin occurred at 9 weeks of gestation. The 10 weeks scan showed a normal fetus which was described to be highly localized in the uterus but the diagnosis of intramyometrial pregnancy was not suspected. The patient was admitted at 14 weeks of gestation with pelvic pain, hemorrhage, and shock. Ultrasound showed an exocentric gestational sac with cardiac activity and suspected rupture of intramyometrial pregnancy. The patient was immediately operated. Surgical exploration showed a partial rupture of the right lateral uterine wall with a conceptus adherent to myometrium without communication with the uterine cavity (Figures 1 and 2). The conceptus was removed and the uterine wall closed with a 2 layers of resorbable sutures. Followup was free of complications and a postoperative hysterosalpingogram (3 months after the surgery) demonstrated no uterine parietal defect nether uterine diverticulitis. The patient had become spontaneously pregnant 11 months after the surgery and is actually at 32 weeks of gestation. Figure 1:
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