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Search Results: 1 - 10 of 272 matches for " Aasim Mushtaq Patloo "
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Primary Malignant Peripheral Nerve Sheath Tumor of the Breast—A Case Report  [PDF]
Mushtaq Chalkoo, Shahnawaz Ahangar, Asim Rafiq Laharwal, Aasim Mushtaq Patloo, Abbass Mohd, Shabir Ahmed Dar
Surgical Science (SS) , 2011, DOI: 10.4236/ss.2011.23028
Abstract: Malignant peripheral nerve sheath tumor is a rare soft tissue sarcoma. Breast is an extremely rare location of this lesion and presentation as a breast lump in the absence of pain or previous benign neural tumor is even rarer. We report such a lesion in a 60 year-old female who presented with hard and painless breast lump for 2 years. Histopathology revealed a malignant spindle cell tumor of low grade potential. It was subsequently confirmed to be malignant peripheral nerve sheath tumor (MPNST) on the basis of immunopositivity for vimentin, neurone specific enolase and S-100.
Laparoscopic retroperitoneal pyelolithotomy and open pyelolithotomy: a comparative study
Asim Mushtaq Patloo,Arif Hussain Sarmast,Mehvish Afzal Khan,Muneer A. Khan
Turkish Journal of Urology , 2012,
Abstract: Objective: To compare the outcomes of laparoscopic pyelolithotomy and open pyelolithotomy at a single center in terms of operative time, blood loss, intra- and post-operative complications, analgesia requirements, hospital stay, convalescence and cosmesis.Material and methods: This prospective randomized study was conducted in the Department of Surgery of the Government Medical College Srinagar between May 2008 and September 2010. Sixty patients underwent pyelolithotomy during this period, including both open pyelolithotomy (n=30) and laparoscopic retroperitoneal pyelolithotomy (n=30). All patients (age >14 yr) with large (>1.5 cm) renal pelvic stones who met the inclusion criteria were included in the study. The decision to perform open or laparoscopic pyelolithotomy was made randomly by a computer program. Results: The majority of our patients in both study groups were in the 21-40 yr age group. The mean operative time was significantly less (p<0.001) in the open group than in the laparoscopic group (74.83 min vs. 94.43 min). The mean blood loss was less in the laparoscopic group than in the open group (73 mL vs. 103 mL); however, this difference was not statistically significant. In the laparoscopic group, both the resumption of oral intake (10.33 hrs vs. 15.60 hrs) and the drain removal (2.7 days vs. 3 days) occurred earlier, although these differences were not significant. Intraoperative complications occurred more frequently in the laparoscopic group (16% versus 6.66%); however, all of the complications were minor and were managed intraoperatively in the same sitting. There was no statistically significant difference in the postoperative pain scores or analgesia requirements, and postoperative complications were only slightly more frequent in the laparoscopic group in our study. The mean hospital stay in the open group was 5.2 days, while the mean stay of the laparoscopic group was 3.8 days (p<0.03). Patients in the laparoscopic group returned to their routine activities significantly earlier (1.78 vs. 3.83 wks) than did patients in the open group (p<0.001).Conclusion: Laparoscopic retroperitoneal pyelolithotomy for upper urinary tract calculi is superior to open surgery because of the significantly reduced hospital stays and cosmetic outcomes of patients who underwent the laparoscopic surgery. Although the reductions of analgesia requirements and blood loss were not statistically significant in our study, the data still favored the laparoscopic procedure. Disadvantages of retroperitoneal laparoscopy include the decreased working space, the cost o
In Vitro Shoot Regeneration of NAA-Pulse Treated Plumular Leaf Explants of Cowpea
Muhammad AASIM
Notulae Scientia Biologicae , 2010,
Abstract: Cowpea (Vigna unguiculata L.) is an economically important grain legume crop and is an important source of dietary protein in many of the developing countries. The present study reports the effect of pulse treatment duration, concentration of NAA and presence of NAA in the culture medium on shoot regeneration from plumular leaf explant of Turkish cowpea cv. ‘Akkiz’ and ‘Karagoz’. Pulse treatment of mature embryos with 20 mg l-1 NAA for 1 and 3 weeks followed by culturing of plumular leaf explant on MS medium containing 0.25, 0.50 and 1.0 BAP with 1.0, 2.0 and 4.0 mg l-1 NAA promoted somatic embryogenesis in both cultivars. Longer duration of pulse treatment was deleterious resulting in browning and consequently death of the embryos on explants. Pulse treatment with 20 mg l-1 NAA for one week was less deleterious and developed two plantlets after the explants were transferred to MS0 medium after 6 weeks through somatic embryogenesis in cv. ‘Akkiz’. Pulse treatment with 10 mg l-1 NAA for 1 week showed 33.33-50.00 % and 25.00-50.00% shoot regeneration frequency in cv. ‘Akkiz’ and ‘Karagoz’ respectively on MS medium containing 0.25-1.00 mg l-1 BAP. Maximum number of 2.50 shoots each per explant were recorded in cv. ‘Akkiz’ and ‘Karagoz’ on MS medium containing 1.00 and 0.50 mg l-1 BAP respectively. Contrarily, maximum shoot length of 8.98 cm of cv. ‘Akkiz’ and 9.42 cm of cv. ‘Karagoz’ was recorded on MS medium containing 0.50 mg l-1 BAP and 1.00 mg l-1 BAP respectively. Regenerated shoots were rooted on MS medium containing 0.5 mg l-1 IBA and and acclimatized in growth room at room temprature where they produced viable seeds.
Acute liver failure following levetiracetam therapy for seizure prophylaxis in traumatic brain injury  [PDF]
Aasim Ali Syed, Christopher D. Adams
Case Reports in Clinical Medicine (CRCM) , 2012, DOI: 10.4236/crcm.2012.12010
Abstract: This case report investigates an uncommon occurrence of drug induced acute liver injury directly associated with the administration of levetiracetam in a patient following traumatic brain injury.
Clinical Presentation and Outcome of Bacterial Meningitis in University Hospital  [PDF]
Maimoona Mushtaq Ahmed
Advances in Infectious Diseases (AID) , 2014, DOI: 10.4236/aid.2014.43019

Purpose: To determine the clinical characteristics and outcome of bacterial meningitis in adult patients using CT, MRI and CSF culture. Methods: Patients admitted to the university hospital with clinical diagnosis of meningitis were included in the present study. All patients were subjected to clinical examination as well as CT, MRI scanning and CSF-bacteriological culture. Results: The age distribution of the patients shows that there is high frequency of symptoms found in the age group between ages 40 - 45. CSF in the present study included WBS, RBC, glucose and protein, which is associated with the adverse outcome. Meningitis can be confirmed by many methods, in the present study three different methods were used, which included CT scan, MRI and CSF analysis and bacterial culture. In CT scan, among the predictors of meningitis, persons with TB (P = 0.037), patients with HIV (P = 0.036) and stroke (P = 0.036) showed significant association. Whereas MRI findings were significantly associated with TB meningitis (P = 0.015). Meningitis was prevalent in the age group of <45. Conclusion: This study highlights the importance of several modalities for diagnosing and predicting the outcome of meningitis in adults.

Giant renal angiomyolipomas and pulmonary lymphangiomyomatosis
Nasir Kiran,Ahmad Aasim
Saudi Journal of Kidney Diseases and Transplantation , 2010,
Abstract: Renal Angiomyolipomas (AML) are benign tumors, which can acquire huge size and when bilateral, they are diagnostic of tuberous sclerosis (TS). Pulmonary Lymphangiomyo-matosis (LAM) is more common in female patients with TS and mostly diagnosed in patients with renal AMLs. We report a case of giant bilateral AMLs and pulmonary LAM in a 48-year-old female patient, who required nephrectomy for life-threatening hemorrhage.
Walnut Trim down Lipid Profile and BMI in Obese Male in Different Ethnic Groups of Quetta Population, Pakistan  [PDF]
Rehana Mushtaq, Rubina Mushtaq, Sobia Khwaja, Zahida Tasawar Khan
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.410139

A total of 64 male obese subjects were randomized to observe the effect of 40 g of walnut in daily breakfast on lipid profile and Body Mass Index (BMI), total Cholesterol (CHO), Triglyceride (TG) High Density Lipoprotein (HDL) cholesterol and Low Density Lipoprotein (LDL) cholesterol in obese male subjects of various ethnics i.e. Baloch (B), Pathan (P), Hazara (H) and Punjabi (PU) residing in Quetta region of Balochistan for this purpose four weeks controlled study was designed. A batch of 32 obese male subjects 8 from each ethnic group as a control and another batch of 32 obese males 8 from each ethnic group as treated were selected. Twelve hour fasting blood samples a day after stoppage of walnut were taken from obese control and obese treated subjects. Daily walnut consumption in obese male subjects evidently demonstrated reduced BMI in all ethnic groups. Walnut supplementation in obese exhibited significant reduction in cholesterol level in Baloch (P < 0.001) and Punjabi (P < 0.01) males. There was profound and statistically significant [B (P < 0.05), P (P < 0.05), H (P < 0.01) and PU (P < 0.05)] elevation in HDL-C in all male ethnic groups. In male sub-population LDL-C was significantly [P (P < 0.01), H (P < 0.001) and PU (P < 0.05)] reduced in these groups. In these subjects walnut supplementation showed pronounced reduction [B (P < 0.001), P (P < 0.05), H (P < 0.001) and PU (P < 0.001)] in triglyceride levels. The constructive influence of walnut on lipid profile suggests that walnut rich diet may have advantageous effects beyond changes in plasma lipid level.

Study of Serum Cholesterol Level in Adult Obese Population of Karachi, Pakistan  [PDF]
Rubina Mushtaq, Rehana Mushtaq, Ambreen Akram, Sobia Khwaja, Shabbir Ahmed
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2014, DOI: 10.4236/ojemd.2014.411024

Background: The present study was planned to investigate the level of cholesterol in obese/non-obese (normal) individuals according to their body mass index (BMI) and age in different population residing in Karachi. Aim: Comparison of serum cholesterol values of obese with normal subjects and comparison of BMI of obese and normal individuals. Methods: Selection of obese subjects was according to the WHO (1998) criteria. A total of 40 subjects 18 - 55 years of age participated in the study, among which 30 subjects (Mean Age = 29.47 ± 1.99) were obese (Mean BMI = 35.41 ± 0.878) and 10 were controls with Mean age = 21.00 ± 0.547 and BMI = 19.96 ± 0.432. An overnight fasting blood sample was obtained and serum total Cholesterol (T-CH) level was estimated. Results: Obese persons having Mean T-CH = 202.6 ± 14.3 and controls having Mean T-CH = 173.3 ± 14.0. The data were further divided into males and females. Obese females were 11 with their BMI 31.836 ± 0.21, mean age ranged at 28.73 ± 4.04 and T-CH 191.8 ± 21.8, while that of control females were 6 in number with their BMI ranged at 19.183 ± 0.507, age 21.000 ± 0.894 and Cholester 148.7 ± 16.0 in controls. Total numbers of obese males were 19 with their BMI ranged at 37.49 ± 1.14, age ranged at 29.89 ± 2.19 and cholesterol level ranged at 208.89 ± 19.1. Control males were 4 in number with their BMI ranged at 21.125 ± 0.075, age 21.250 ± 0.479 and their T-CH 128.7 ± 8.72. Conclusion: The results of current study have reflected that BMI and total cholesterol concentration are higher in obese subjects.

Effect of TRH and TSH on Circulatory Glucose and Fatty Acids Responses in Hypoinsulenemic Male Dwarf Goats  [PDF]
Rubina Mushtaq, Rehana Mushtaq, Abdul Majeed Cheema, Sobia Khwaja
Advances in Bioscience and Biotechnology (ABB) , 2014, DOI: 10.4236/abb.2014.513113
Abstract: Diabetes mellitus or hypoinsulinemia was induced successfully in the male dwarf goats aged be-tween 2 - 3 years with 2 consecutive administrations of streptozotocin. A comparable group of intact control goats was also maintained. In ruminants including goats unlike non-ruminants, insulin generally displays ineffectiveness or resistance in their biochemical setup to facilitate gluco-neogenesis, the only source of glucose in these animals. In present study almost in the absence of insulin through induced hypoinsulinemia the effects of thyrotropin releasing hormone (TRH) (30 μg/kg body weight) and thyroid stimulating hormone (TSH) (2.5 μg/kg body weight) on circulatory glucose and different fatty acid fractions were studied in insulin resistant ruminant model. Fatty acid fractions were estimated by gas chromatography. Both TRH and TSH administration lowered glycemia in insulin deficient goats compared to the controls but significantly with TSH dose only. In intact goats the detectable circulating long chain fatty acids (LCFAs) fractions of lauric, myristic, palmitic, stearic, oleic and linoleic acid were undetected except linoleic acid in the hypoinsulinemic state, however were found restored following TRH and TSH administrations and some of LCFAs; stearic (6417%), oleic (1676%) and linoleic acid (1225%) increased exceptionally with TSH dose. In Intact goats however the hormones variedly increased the fractions. The volatile fatty acid fractions (VFAs) of formic, acetic, propionic, iso-butyric, n-butyric, iso-valeric, n-valeric, iso-caproic, n-caproic and heptanoic acid were detected in the goats. The most VFAs fractions markedly increased in hypoinsulinemic goats compared to the control goats following TRH and TSH infusion. These results have indicated that endogenously stimulated thyroid hormones with TRH and TSH in insulin deficient state inhibit the mechanisms of utilizing the fatty acids in glucose production. Therefore the study reveals thyroid hormones inhibitory effects on gluconeogenesis in insulin resistance and hyperglycemia.
Mushtaq Ahmad
Academic Research International , 2013,
Abstract: Generally, Donne is read and taught as a metaphysical poet and not a theorist. The paper aims to present Donne as a theorist of love, and discusses multidimensional aspects of his theory implicitly presented in his poetry. Through thematic analysis of his poetry, his theory can be established on various key points, of which ardent, platonic, spiritual, carnal, cynical, brutal, flirtatious and venomous ones are significant.
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