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Search Results: 1 - 10 of 556091 matches for " A. K. Anand "
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Cortico-basal ganglionic degeneration--a frequently undetected syndrome.
Anand K,Biswas A,Prasad A
Neurology India , 2000,
Abstract:
Spectrum of aetiological agents of postoperative endophthalmitis and antibiotic susceptibility of bacterial isolates.
Anand A.,Therese K.,Madhavan Hajib
Indian Journal of Ophthalmology , 2000,
Abstract: PURPOSE: To determine the spectrum of infectious agents of postoperative endophthalmitis, the relationship with the time of onset of symptoms after surgery and the antibiotic susceptibilities of the aerobic bacterial isolates. METHODS: A retrospective review of microbiological records from January 1995 to December 1998 yielded 173 isolates from intraocular specimen of 170 patients with culture-proven postoperative endophthalmitis. Antibiotic susceptibility of these isolates was determined for various ocular antibiotics using the Kirby-Bauer disk-diffusion test. Based on the time of onset of illness, clinical presentation was classified into acute, delayed and chronic. RESULTS: Among 170 cases, 71 (41.7%) were attributable to gram-negative, 64 (37.6%) to gram-positive bacteria, and 37 (21.8%) to fungi. Gram-negative bacteria included P. aeruginosa (29;17.1%), other Pseudomonas spp (15;8.8%), non-fermenters (18;10.6%) and others (10;5.8%). Among these, 40 of 72 (55.5%) were sensitive to gentamicin, 47 of 72 (65.2%) to cefotaxime, 47 of 69 (68.1%) to amikacin, 52 of 71 (73.2%) to ciprofloxacin, and 25 of 40 (62.5%) to ceftazidime. The gram-positive bacteria included S. epidermidis (22;12.9%), S. aureus (13;7.6%), P. acnes (10;5.9%), Enterococcus spp (4;2.3%), Streptococcus spp (7;4.1%) and others (8;4.8%). Among these, 41 of 53 (77.3%) were sensitive to gentamicin, 47 of 53 (88.6%) to cefotaxime, 46 of 52 (88.4%) to ciprofloxacin, 38 of 41 (92.6%) to cefazolin and 27 of 37 (72.9%) to ceftazidime. All gram-positive bacteria were sensitive to vancomycin. CONCLUSION: In this large series of postoperative endophthalmitis, gram-negative bacilli followed by fungi accounted for the largest number of cases. A high degree of resistance of gram-negative bacilli to gentamicin, cefotaxime, amikacin and ceftazidime was recorded.
Phenylpropanolamine-induced intraventricular hemorrhage
Prasad A,Bhoi K,Bala K,Anand K
Neurology India , 2003,
Abstract: Intracranial hemorrhage is an uncommon complication of phenylpropanolamine. There is an increasing awareness of this complication in the West. However, to the best of our knowledge there have been no cases reported from India. Here we report a patient who developed Intraventricular hemorrhage following ingestion of Phenylpropanolamine, from which he made an uneventul recovery over the next two weeks.
Nimotuzumab with Concurrent Chemoradiation in Inoperable Locally Advanced Squamous Cell Carcinoma of Head and Neck: An Indian Experience  [PDF]
Ankur Bahl, Komal Singh, Pragati Choudhary, A. K. Anand, Amal Roy Chaoudhoory, Harit Chaturvedi, Biswajyoti Hazarika, Dilip Pawar
Journal of Cancer Therapy (JCT) , 2018, DOI: 10.4236/jct.2018.91010
Abstract: Background: The prognosis of patients with Epidermal Growth Factor Receptor (EGFR) overexpression in inoperable Locally Advanced Squamous Cell Carcinoma of Head and Neck (LASCCHN) remains poor. Nimotuzumab is an Anti EGFR humanized monoclonal antibody approved for treatment of LASCCHN, with concurrent chemoradiation. Objective: To assess the efficacy and safety of nimotuzumab with concurrent chemoradiation in inoperable LASCCHN patients. Methodology: This is a single-centre, single arm, retrospective study evaluating 35 patients with histologically confirmed inoperable LASCCHN (stages III-IV). The patients were administered IV cisplatin 50 mg/m2 and IV nimotuzumab 200 mg for 6 - 7 weeks, along with radiotherapy of 6600 - 7000 cGy over 35 fractions. Patients were evaluated over response evaluation criteria in solid tumors (RECIST) criteria 12 weeks after the last cycle of chemotherapy. They were also followed up for overall survival and relapse free survival. Results: The median duration of follow-up was 20 months. The most common site of cancer was oropharynx (68.6%). One patient was lost to follow up. Objective Response Rate (ORR) was observed in 97% of the patients with 17 patients (48.6%) achieving complete response (CR) and 17 patients (48.6%) achieving partial response (PR). The median overall survival was 22.7 months (95% CI: 21.30, 34.27). The median relapse free survival was 16.7 months (95% CI: 9.80, 24.50). Nimotuzumab was safe and well tolerated with few mild, self-limiting adverse events
Nitric Oxide In Health And Diseases
Chinmay Shah,R.Dixit,A.K. Anand
Global Journal of Medicine and Public Health , 2012,
Abstract: Nitric Oxide (NO) is color less, readily diffusible, highly reactive lipophilic and chemically unstable Free radical gas. NO is formed form arginine by enzyme nitric Oxide synthase. No acts in a paracrine or even autocrine manner. It causes asodilatation, act as neurotransmitter, Prevent Platelet aggregation and also play important role in macrophase function. Deficiency leads to, increase vascular tone, reduced thrombolitic activity. Use of NO in pediatric pulmonary hypertension and in sexual dysfunction is increases day by day. The discovery of NO as an essential effectors of many Biological
PROTECTIVE ROLE OF ETHANOLIC EXTRACT OF HYBANTHUS ENNEASPERMUS ON MITOCHONDRIAL MEMBRANE Na+/K+ATPase, Ca2+ATPase AND Mg2+ATPase ACTIVITIES ON CARBON TETRACHLORIDE INDUCED OXIDATIVE STRESS IN RATS
Anand T,Gokulakrishnan K,Kalaiselvan A,Velaven S
International Research Journal of Pharmacy , 2012,
Abstract: In this present study, we evaluated the liver mitochondrial membrane ATPases activities on carbon tetrachloride induced oxidative stress in rats. Wistar strain male albino rats were divided into four groups. Group I animals were served as normal and group II was administrated with corn oil as vehicle control. Group III was given single dose (29th day) of CCl4 in corn oil (1:1 v/v, 3ml/kg, i.p.). Groups IV was treated with ethanolic extract of Hybanthus enneaspermus. (Orally at the dose of 500mg per kg body weight). In CCl4 + Hybanthus enneaspermus treated rats, Na+/K+ATPase, Ca2+ATPase and Mg2+ATPase activities were attained normally when compared with CCl4 treated rats.
A geometric algorithm for efficient coincident detection of gravitational waves
C. A. K. Robinson,B. S. Sathyaprakash,Anand S. Sengupta
Physics , 2008, DOI: 10.1103/PhysRevD.78.062002
Abstract: Data from a network of gravitational wave detectors can be analyzed in coincidence to increase detection confidence and reduce non-stationarity of the background. We propose and explore a geometric algorithm to combine the data from a network of detectors. The algorithm makes optimal use of the variances and covariances that exist amongst the different parameters of a signal in a coincident detection of events. The new algorithm essentially associates with each trigger ellipsoidal regions in parameter space defined by the covariance matrix. Triggers from different detectors are deemed to be in coincidence if their ellipsoids have a non-zero overlap. Compared to an algorithm that uses uncorrelated windows separately for each of the signal parameters, the new algorithm greatly reduces the background rate thereby increasing detection efficiency at a given false alarm rate.
Eigenfrequencies of Radial Pulsations of Strange Quark Stars
B. Datta,Pradip K. Sahu,J. D. Anand,A. Goyal
Physics , 1993, DOI: 10.1016/0370-2693(92)90025-Y
Abstract: We calculate the range of eigenfrequencies of radial pulsations of stable strange quark stars, using the general relativistic pulsation equation and adopting realistic equation of state for degenerate strange quark matter.
Investigations of the effect of nonmagnetic Ca substitution for magnetic Dy on spin-freezing in Dy2Ti2O7
V. K. Anand,D. A. Tennant,B. Lake
Physics , 2015, DOI: 10.1088/0953-8984/27/43/436001
Abstract: Physical properties of partially Ca substituted hole-doped Dy2Ti2O7 have been investigated by ac magnetic susceptibility \chi_ac(T), dc magnetic susceptibility \chi(T), isothermal magnetization M(H) and heat capacity C_p(T) measurements on Dy1.8Ca0.2Ti2O7. The spin-ice system Dy2Ti2O7 exhibits a spin-glass type freezing behavior near 16 K. Our frequency dependent \chi_ac(T) data of Dy1.8Ca0.2Ti2O7 show that the spin-freezing behavior is significantly influenced by Ca substitution. The effect of partial nonmagnetic Ca2+ substitution for magnetic Dy3+ is similar to the previous study on nonmagnetic isovalent Y3+ substituted Dy2-xYxTi2O7 (for low levels of dilution), however the suppression of spin-freezing behavior is substantially stronger for Ca than Y. The Cole-Cole plot analysis reveals semicircular character and a single relaxation mode in Dy1.8Ca0.2Ti2O7 as for Dy2Ti2O7. No noticeable change in the insulating behavior of Dy2Ti2O7 results from the holes produced by 10% Ca2+ substitution for Dy3+ ions.
Ferromagnetic cluster spin-glass behavior in PrRhSn3
V. K. Anand,D. T. Adroja,A. D. Hillier
Physics , 2014, DOI: 10.1103/PhysRevB.85.014418
Abstract: We report the synthesis, structure, and magnetic and transport properties of a new ternary intermetallic compound PrRhSn3 which crystallizes in LaRuSn3-type cubic structure (space group Pm-3n). At low applied fields the dc magnetic susceptibility exhibits a sharp anomaly below 6~K with an irreversible behavior in zero field cooled (ZFC) and field cooled (FC) susceptibility below 5.5 K. The ac susceptibility exhibits a frequency dependent anomaly revealing a spin-glass behavior with a freezing temperature, T_f = 4.3 K. The observation of spin-glass behavior is further supported by a very slow decay of thermo-remnant magnetization (mean relaxation time tau = 2149 s). However, a small jump at very low field in the isothermal magnetization at 2 K and a weak anomaly in the specific heat near 5.5 K reveal the presence of ferromagnetic clusters. The frequency dependence of the transition temperature T_f in the ac susceptibility obeys the Vogel-Fulcher law, nu = nu_0exp[-E_a/k_B(T_f-T_0)] with activation energy E_a/k_B = 19.1 K. This together with an intermediate value of the parameter delta T_f = Delta T_f/T_f Delta(log nu) = 0.086 provide an evidence for the formation of a cluster-glass state in PrRhSn3. The magnetic contribution of the specific heat reveals a broad Schottky-type anomaly centered around 10 K and the analysis based on the crystal electric field model indicates a singlet ground state. Further, below T_f the magnetic part of the specific heat exhibits a T^{3/2} temperature dependence. The strong influence of the crystal electric field and a T^{3/2} temperature dependence are also seen in the electrical resistivity which reveals a metallic character and a high magnetoresistance. We also obtain a surprisingly large value of Sommerfeld-Wilson ratio R_W ~ 247$.
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