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Search Results: 1 - 10 of 512820 matches for " A. I. Sadek "
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B-carotene Lock the Effect of Acrylamide on Liver in the Egyptian Toad
I. A. Sadek,A. Abou-Gabal
Pakistan Journal of Biological Sciences , 1999,
Abstract: Several studies on the harmful effects of chemical pollutants have had an increasing influence on public cancer policy. It has been shown that acrylamide, which is widely used in the synthesis of variety of polymers, induced liver tumor in the Egyptian toad (9 cases out of 50 cases). The liver tumor was diagnosed as hepatocellular carcinoma. In contrast toads treated with acrylamide and B-carotene (3 hr. prior to the carcinogen) completely blocked the hepatocarcinogenesis in toads. However B-carotene was less effective when administered 3hr, after the carcinogen (acrylamide) in 7 out of 50 cases. It is concluded that B-carotene has an inhibitory effect on hepatocarcinogenesis in toads during initiation.
Curcumin and its Effect on Cytochrome P450 and GST in Toad Liver Tumor Induced by DMBA
H. Abdel-Latif,I. A. Sadek
Pakistan Journal of Biological Sciences , 1999,
Abstract: Curcumin has been used as a colouring agent and spice in many food. The present results clearly demonstrated that toads received 0.5 mg curcumin and 0.5 mg DMBA/toad, 3 times/week for 12 weeks, showed a significant decrease in tumor incidence (3 out of 50 cases) in comparison with that treated with DMBA alone (12 out of 50 cases). At the same time, curcumin reduce the activity of liver microsomal cytochrome P450s and cytosolic GTSS enzymes in toads previously treated with DMBA. The present data suggest that curcumin decrease incidence of liver tumor in toads through inhibition of cytochrome P45O and GST activities. The present report was undertaken for two reasons. First to determine whether curcumin, which are widely used in food have anticarcinogenic effect on the liver of the Egyptian toad. Second, are curcumin effect on microsomal cytochrome P450 and GST activities to shed more light on the mechanisms (s) of action.
On the Stability of Solutions of Nonlinear Functional Differential Equation of the Fifth-Order  [PDF]
A. M. A. Abou-El-Ela, A. I. Sadek, A. M. Mahmoud, R. O. A. Taie
Advances in Pure Mathematics (APM) , 2014, DOI: 10.4236/apm.2014.48046

The main purpose of this paper is to investigate global asymptotic stability of the zero solution of the fifth-order nonlinear delay differential equation on the following form

By constructing a Lyapunov functional, sufficient conditions for the stability of the zero solution of this equation are established.

The Bacterial Load of Hospital Discharges (Sidi Kacem, Morocco)  [PDF]
Sanae Sadek, F. Benel Harkati, K. Elkharrim, F. Jeddi, I. Rhiate Moufouad, M. Elmarkhi, A. Khadmaoui, S. Mouden, Z. Dakir, D. Belghyti
Advances in Microbiology (AiM) , 2013, DOI: 10.4236/aim.2013.37068

Fecal microorganisms, which are indicators or pathogens, have an optimum growth in the specific conditions of the internal environment animal or human. Therefore, when issued by a host, they result in sudden and drastic changes in the environment. This study aims at bacteriological characterization of the effluent from the provincial hospital in Sidi Kacem. And it shows that the effluent from the hospital contributing to non-regulatory standards ultimately reaches the environment (river wadi floor, animal, vegetable...). The results of bacteriological analyses (Total Coliforms, Fecal Coliforms) about sewage from the provincial hospital depending on the day of rest and work in the city of Sidi Kacem are presented with means respectively 557 × 104 and 328 × 104 in the rest and work

Existence and Uniqueness of a Periodic Solution for Third-order Delay Differential Equation with Two Deviating Arguments
A. M. A. Abou-El-Ela,A. I. Sadek,A. M. Mahmoud
IAENG International Journal of Applied Mathematics , 2012,
Anti-inflammatory Drug (Indomethacin) and its Effect on Liver Tumor Induced by DMBA
N.E. Abdelmeguid,I.A. Sadek,J. M. Sorour,A.A. Attia
Pakistan Journal of Biological Sciences , 1999,
Abstract: Liver tumors were induced in the toads, Bufo regularis, , in 16 out of 50 cases by the administration of 0.2 mg DMBA/toad, 3 times / week for 12 weeks. Light and electron microscopic photographs demonstrate that these hepatocytes of DMBA - treated toads showed criteria of malignancy. In contrast, toads treated with DMBA at the same dose level and 0.005 per cent w/w indomethacin / toad, 3 times / week for 12 weeks showed a lower incidence of liver tumors, 8 out of 50 cases. The biochemical analysis showed that the activity of G6PD, LDH, acid phosphatase and alkaline phosphatase enzymes were decreased in animals treated with DMBA and indomethacin in comparison with toads treated with DMBA alone. It is concluded that indomethacin has an inhibitory effect on hepatocarcinogenesis in toads.
Effect of Corn Oil on Liver Glycogen Content and Blood Glucose-6-phosphatase Dehydrogenase in Toads Treated with DMBA
N.E. Abdelmeguid,I. A. Sadek,J. M. Sorour,A. A. Attia
Pakistan Journal of Biological Sciences , 2000,
Abstract: Environmental factors play an important role in the etiology of several types of cancer, this discovery has led to a great deal of interest in the role of diet in cancer etiology. Fed the Egyptian toad with 0.5 ml corn oil and 0.2 mg DMBA toad/3, 3 times/week increased the incidence of liver tumor (22 out of 50 cases) in comparison with toads treated with DMBA alone (16 out of 50 cases). On the ultrastructural level, corn oil increased (a) the depletion of glycogen, (b) accumulation of fat and lysosomes in toad liver tumor. The biochemical data indicated that glucose-6 phosphatase dehydrogenase in the blood, acid and alkaline phosphatase enzymes activities were increased in serum of toads treated with DMBA and corn oil than animals treated with DMBA alone.
Relationship Between 13-cis-retinoic Acid or Retinol Acetate and Ratio of Spermatogenesis, Diameter of Semniferous Tubules and Number of Leydig Cells in Gerbillus cheesemani
I.A. Sadek,A.A. Abou-Gabal,M.H. Abdul-Mohsen
Pakistan Journal of Biological Sciences , 1999,
Abstract: The results of the present study showed that administration of 13-cis-retinoic acid or retinol acetate for 6 weeks reduced the diameter of the seminiferous tubules in the testes of Gerbillus chessemani. Also, a decrease in the Leydig cell count was observed. However, the ratio of spermatogenesis was decreased only by 13-cis-retinoic acid administration. On the other hand the ratio of spermatogenesis, diameter of seminiferous tubules and number of Leydig cells were nearly normal in the experimental animals after 12 week of withdrawal treatment of drugs.
Meteorological Indices Approach for Prediction of Thunderstorm Probability at Two Coastal Sites in Egypt  [PDF]
O. S. Ahmed, M. A. Sadek
Atmospheric and Climate Sciences (ACS) , 2015, DOI: 10.4236/acs.2015.53016
Abstract: Siting of hazardous facilities such as Nuclear power plants requires the investigation of the meteorological and climatologically of the site region to derive extreme values of the meteorological variables to be considered in the design for safety purposes. Not only normally occurring meteorological conditions but also extremely rare events are considered. The present work is devoted to predict the likelihood of the Thunderstorm which is one of the rare events of concern for plant safety. Four atmospheric stability indices such as K-indices, the Showalter-indices, total totals-indices and the SWEAT-indices have been used for that. These function of meteorological parameters such as temperature, wind speed, wind direction and dew point at levels of pressure at 500, 700 and 850 hpa to predict the thunderstorm probability. Two Egyptian coastal sities have been chosen for the investigation, one on the Mediterranean Sea and the other on Red Sea; El Sallum and Sharm El Sheikh. The results show that the probability of thunderstorm occurred within the months January and February during 1989-2003, where the maximum value of SI, K, TT and SWEAT indices at January & February months equals 29.31 & 28.20, 18.4 & 20.3 & 48.1 & 49 and 238.01 & 350.6 for Sallum city respectively, and equals 26.05 & 24.53, 24.6 & 23.9, 50.6 & 51.5 and 253.4 & 265.4 for Sharm El Sheikh city respectively, and this agrees with the pattern reviewed based on world geographic and climatic condition.
Baher A.M. Effat,Ahmed M.M. Mabrouk,Zainab I. Sadek,Gehan A.M. Hussein
Journal of Microbiology, Biotechnology and Food Sciences , 2012, DOI: 13385178
Abstract: The increasing side effects and the cost of allopathic medicines make the consumer incline towards alternative therapeutic agents. As dietary supplements are the most consumers acceptable therapeutic agents the present study was carried out to develop a symbiotic soft cheese with new Lactobacillus strains. Synbiotic white soft cheese was manufactured using starter cultures containing Str. thermophilus as a main strain mixed (1:1) with one of the selected Lactobacillus strains (Lb. delbrueckii ssp. bulgaricus, Lb. johnsonii NRRL B-2178, Lb. hilgardii NRRL B-1843 and Lb. curvatus NBIMCC-3452) with adding one of the selected prebiotics (dextrin and litesse) at the rate of 3 %. The moisture content, the pH values, titratable acidity, total nitrogen content % and soluble nitrogen %. as well as the bacteriological and organoleptic properties during storage at 7 C for 30 days of symbiotic white soft cheeses were evaluated. The results revealed that, there was significant difference (p<0.05) in all studied properties of white soft cheese .Moreover, symbiotic white soft cheese manufactured with synbiotic cultures containing probiotic Lb.curvatus NBIMCC-3452 and 3% of prebiotics (dextin or litesse) had the highest viability of these strains. The highest average sensory evaluation points were recorded in cheeses made with Str. thermophilus plus Lb. johnsonii NRRL B- 2178 (1:1) and 3 % dextrin; and Str. thermophilus plus Lb. curvatus NBIMC 3452 (1:1) and 3 % litesse at 20 days of refrigeration storage. Finally, it could be recommended that combination among dextrin or litesse as prebiotics with Lactobacillus strains (Lb. hilgardii NRRL B-1843, Lb johnsonii NRRL B-2178 ad Lb. curvatus NBIMCC-3452) as probiotics for manufacturing symbiotic white soft cheeses with high quality and healthy properties. This could be providing with an additional symbiotic dairy product.
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