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Search Results: 1 - 10 of 461683 matches for " A. Ganapathi "
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Synthesis, Spectral, Anti-Liver Cancer and Free Radical Scavenging Activity of New Azabicyclic Thienoyl Hydrazone Derivatives  [PDF]
M. Manimaran, A. Ganapathi, T. Balasankar
Open Journal of Medicinal Chemistry (OJMC) , 2015, DOI: 10.4236/ojmc.2015.53004
Abstract: To exploit the potential biological activities of azabicyclic based, seven 2r, 4c-diaryl-3-azabicyclo [3.3.1] nonan-9-one-2’-thienoyl hydrazone were synthesized. The structural elucidation and stereochemistry of these compound assigned by FT-IR, 1H, 13C and 2D NMR spectral data. The Structural Activity Relationship (SAR) of the target compounds were examined for their in vitro anti-proliferative, antioxidant and antimicrobial activities. The initial screen was treated against human liver cancer cell lines (HepG2) with IC50 values determined by MTT assay. Fluoro substitution at para position of phenyl ring compound 12 showed more antiproliferative activity against HepG2 at half maximum inhibitory concentration (IC50 = 3.76 μg/mL) than other target hydrazones. The mechanism of the antitumor action of active compound 12 was investigated through Hoechst stain 33342 analyses. It indicated that the compound inhibited HepG2 cancer cells proliferation by triggering apoptotic cell death. The Free radical scavenging activity of all synthesized compounds were evaluated with \"\", \"\" and \"\" radicals. The compounds 11 (IC50 rang 3.78 - 4.31 μg/mL) and 15 (IC50 rang 4.61 - 5.16 μg/mL) were exhibited higher free radical scavenging activity than standard BHT drug. Besides, all the target compounds were screened for their in vitro antibacterial and antifungal activity against a spectrum of microbial organisms by using twofold dilution method. These studies proved that halogen substituted compounds 12, 13 and 14 were showed excellent inhibitory potency at lowest minimum inhibitory concentration (MIC) range of 6.25 - 25.5 μg/mL. Nevertheless, multiple mechanisms regulating the antioxidant and anticancer effects of the hybrid molecules need to be further investigations.
Production of Biodiesel from Non-edible Plant Oils having High FFA Content
Mathiyazhagan M.,Mathiyazhagan M.,Ganapathi A.,Ganapathi A.
International Journal of Chemical and Environmental Engineering , 2011,
Abstract: Biodiesel is a more attractive alternative fuel to diesel engines. Because, it is a renewable and non-polluted fuel that can be producedfrom plant and animal fats. Biodiesel emits low pollutants (except NOx) than petroleum diesel. But the major problem arises for thecommercialization of biodiesel is its cost. Since most of the biodiesels were derived from edible oils like soy bean, sunflower,rapeseed, palm etc. These oils are essentially edible in India and other developing countries. On the other hand, diversion of edible oilsas feed stocks for biodiesel production leads to food crisis. Therefore this research mainly concentrates the non-edible oils as feedstocks for biodiesel production to reduce the cost of biodiesel. Normally alkali catalyzed method was followed for biodieselproduction process. However the non-edible oils having high FFA content which is not suitable for normal transesterification process.Hence a two-step catalyzed method was used to prepare the biodiesel. For this study the following non-edible oil samples such asJatropha, Pongamia, Madhuca and Azhadirachta were used to extract the biodiesel. For this study biodiesel yield from various nonedibleoils and its cost optimization were discussed.
Factors Affecting Biodiesel Production
Research in Plant Biology , 2011,
Abstract: Biodiesel is a renewable alternate fuel to diesel engines that could be partially orfully replace or reduce the use of petroleum diesel fuel. Biodiesel can be produced fromplant and animal fats through transesterification reaction. The transesterification reaction isaffected by molar ratio of alcohol, presence of water and Free Fatty Acid content, reactiontemperature, catalyst concentration and agitation speed. This review paper discuss aboutthe factors involved in transesterification reaction.
Removal of Grey BL from Dye Wastewater by Derris (Pongamia Glabra) Leaf Powder by Adsorption
T. Mugugan,A. Ganapathi,R. Valliappan
Journal of Chemistry , 2010, DOI: 10.1155/2010/938692
Removal of Dyes from Aqueous Solution by Adsorption on Biomass of Mango (Mangifera Indica) Leaves
T. Murugan,A. Ganapathi,R. Valliappan
Journal of Chemistry , 2010, DOI: 10.1155/2010/127020
Removal of Direct Yellow-12 Dye from Water by Adsorption on Activated Carbon Prepared from Ficus Racemosa L.
G. Revathi,S. Ramalingam,P. Subramaniam,A. Ganapathi
Journal of Chemistry , 2011, DOI: 10.1155/2011/902421
Panel flutter characteristics of sandwich plates with CNT reinforced face sheets using an accurate higher-order theory
A Sankar,S Natarajan,M Haboussi,K Ramajeyathilagam,M Ganapathi
Physics , 2014, DOI: 10.1016/j.jfluidstructs.2014.06.028
Abstract: In this paper, the flutter characteristics of sandwich panels with carbon nanotube (CNT) reinforced face sheets are investigated using QUAD-8 shear flexible element developed based on higher-order structural theory. The formulation accounts for the realistic variation of the displacements through the thickness, the possible discontinuity in the slope at the interface, and the thickness stretch affecting the transverse deflection. The in-plane and rotary inertia terms are also included in the formulation. The first-order high Mach number approximation to linear potential flow theory is employed for evaluating the aerodynamic pressure. The solutions of the complex eigenvalue problem, developed based on Lagrange's equation of motion are obtained using the standard method for finding the eigenvalues. The accuracy of the present formulation is demonstrated considering the problems for which solutions are available. A detailed numerical study is carried out to bring out the efficacy of the higher-order model over the first-order theory and also to examine the influence of the volume fraction of the CNT, core-to-face sheet thickness, the plate thickness and the aspect ratio, damping and the temperature on the flutter boundaries and the associated vibration modes.
An Overview of Cloud Computing Technology
Mythry Vuyyuru,Pulipati Annapurna,K.Ganapathi Babu,A.S.K Ratnam
International Journal of Soft Computing & Engineering , 2012,
Abstract: Cloud computing is a model for enabling convenient, on-demand network access to a shared pool of configurable computing resources (eg networks, servers, storage, applications, and services) that can be rapidly provisioned and released with minimal management effort or service provider interaction. It has become a significant technology trend, and many experts expect that cloud computing will reshape information technology (IT) processes and the IT marketplace. With the cloud computing technology, users use a variety of devices, including PCs, laptops, smart phones, and PDAs to access programs, storage, and application-development platforms over the Internet, via services offered by cloud computing providers. This paper presents an overview of cloud computing technology- deployment models, classes and characteristics.
Reference Point Group Mobility and Random Waypoint Models in Performance Evaluation of MANET Routing Protocols
Geetha Jayakumar,Gopinath Ganapathi
Journal of Computer Networks and Communications , 2008, DOI: 10.1155/2008/860364
Abstract: Ad hoc networks are characterized by multihop wireless connectivity, frequently changing network topology and the need for efficient dynamic routing protocols plays an important role. We compare the performance of two prominent on-demand routing protocols for mobile ad hoc networks: dynamic source routing (DSR), ad hoc on-demand distance vector routing (AODV). A detailed simulation model with medium access control (MAC) and physical layer models is used to study the interlayer interactions and their performance implications. We demonstrate that even though DSR and AODV share similar on-demand behavior, the differences in the protocol mechanisms can lead to significant performance differentials. In this paper, we examine both on-demand routing protocols AODV and DSR based on packet delivery ratio, normalized routing load, normalized MAC load, average end-to-end delay by varying the node density, network loading, and mobility variations for reference point group mobility and random waypoint models. This framework aims to evaluate the effect of mobility models on the performance of mobile ad hoc networks (MANETs) routing protocols. Our results show that the protocol performance may vary drastically across mobility models and performance rankings of protocols may vary with the mobility models used. This effect can be explained by the interaction of the mobility characteristics with the connectivity graph properties.
Muthu Ganapathi Subramanian Annasamy
Pakistan Journal of Statistics and Operation Research , 2010, DOI: 10.1234/pjsor.v6i2.154
Abstract: Consider a single server retrial queueing system with pre-emptive priority service and vacation interruptions in which customers arrive in a Poisson process with arrival rate λ1 for low priority customers and λ2 for high priority customers. Further it is assume that the service times follow an exponential distribution with parameters μ1 and μ2 for low and high priority customers respectively. The retrial is introduced for low priority customers only. The server goes for vacation after exhaustively completing the service to both types of customers. The vacation rate follows an exponential distribution with parameter α. The concept of vacation interruption is used in this paper that is the server comes from the vacation into normal working condition without completing his vacation period subject to some conditions. Let k be the maximum number of waiting spaces for high priority customers in front of the service station. The high priority customers will be governed by the pre-emptive priority service. We assume that the access from orbit to the service facility is governed by the classical retrial policy. This model is solved by using Matrix geometric Technique. Numerical study have been done for Analysis of Mean number of low priority customers in the orbit (MNCO), Mean number of high priority customers in the queue(MPQL),Truncation level (OCUT),Probability of server free and Probabilities of server busy with low and high priority customers and probability of server in vacation for various values of λ1 , λ2 , μ1 , μ2, α and σ in elaborate manner and also various particular cases of this model have been discussed.
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