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Search Results: 1 - 10 of 677215 matches for " A. C. B. "
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Pollution Tolerance of Smoke in the Distribution of Neurotransmitter Enzyme (Acetylcholine Esterase) and Total Cholesterol in Tissues of Wistar Rats  [PDF]
A. C. Achudume, F. Aina, B. Onibere
Journal of Environmental Protection (JEP) , 2010, DOI: 10.4236/jep.2010.14055
Abstract: This study was designed to assess total animal exposure to non-occupational but environmentally induced smoke through short-term landfill burning toxicity tests at the biochemical levels. Exposure to municipal land-fill burning using rat model focused primarily on inhalation exposure. The environmental monitoring consisted of 60 days exposure to refuse burning by evaluating the level of protein concentrations, neurotransmitter enzyme acetylcholine esterase (AcHE), and total cholesterol in different tissues of Wistar rats. Protein concentrations tended to decrease in the brain, liver and kidney and slightly increased in the plasma while acetylcholine esterase decreased in brain and liver and increased in the kidney. The non-depletion in total cholesterol levels in the tissues tended to be due to active mobilization towards tissue metabolism. The data were sufficient to support risk assessment for human.
Resveratrol Reverses the Impaired Vasodilation Observed in 2K-1C Hypertension through Endothelial Function Improvement  [PDF]
B. F. M. Pereira, A. C. Scalabrini, T. S. Marinho, C. R. K. Antonietto, C. B. A. Restini
Open Journal of Medicinal Chemistry (OJMC) , 2014, DOI: 10.4236/ojmc.2014.42004
Background: The production of endothelial-derived factors induces either vasoconstriction or vasodilation; nitric oxide (NO) is the most distinguished relaxing factor. Endothelial dysfunction is associated with hypertension. The partial loss in the NO-promoted vasodilation is due to its decreased bioavailability and/or to an activity reduction of endothelium NO synthase (eNOS). Reactive oxygen species (ROS), present in oxidative stress, seize NO and diminish its bioavailability. Transresveratrol (RESV) has been proved to increase NO and eNOS levels. Thus, RESV could be capable of improving NO dependent vascular relaxation on aortic rings isolated from treated 2K-1C animals through ROS damage reduction. Aim: Evaluate the effects of RESV treatment on the relaxation of aortic rings isolated from treated 2K-1C rats while focusing on the effects of the treatment on systolic blood pressure. Methods: Male Wistar rats (180 g) were grouped: two 2K-1C and two Sham groups, one of each was treated with RESV (20 mg/kg, gavage) dissolved in Tween 80 and one of each was treated with water plus Tween 80 (control) for six weeks. The rats had their systolic blood pressure (SBP) measured before and after the treatments. Vascular reactivity studies were conducted in order to observe and compare acetylcholine (ACh)-induced relaxations in the presence and absence of the NOS inhibitor L-NAME (10-4 mol/L). Results: SBP for 2K-1C was significantly reduced in the treated group (179.13 ± 4.90 mmHg, n = 23) when compared to the untreated group (196.66 ± 6.06 mmHg, n = 15, p < 0.01). The maximum relaxation of aortic rings isolated from the 2K-1C treated group showed a higher efficacy (116.63% ± 1.72%, n = 12) than that from the untreated group (85.97% ± 0.69%, n = 6, p < 0.001); L-NAME exposure was responsible for a significant decrease in each group’s maximum relaxation efficacy. Conclusions: SBP reduction observed after RESV treatment in rat renal hypertension could be due to the reestablishment of vascular relaxation depend of NO.
The Mixing Matrix for a 3+2 Model
Machado, A. C. B.
High Energy Physics - Phenomenology , 2008,
Abstract: In this work we present the characterization of the mixing matrix when the mass matrix is considered, without seesaw, for 3+2 models like.
Profitability Analysis of Pig Production under Intensive Management System in Nsukka Local Government Area of Enugu State, Nigeria
Ezeibe, A. B. C.
International Journal of Economic Development Research and Investment , 2010,
Abstract: The study examined the profitability of pig production under intensive management system in Nsukka Local Government Area in the year 2009. Data were obtained from five notable intensive pig farmers and their employees through well structured questionnaire and oral interviews. Data were analyzed using profitability tools like Gross Margin, Net Revenue and Cost Benefit Ratio. Findings showed that under one production year, the gross margin was N1,182,000 while Net Revenue was N1,004,750 and the Cost Benefit Ratio (CBR) was 1.30 which indicates that the enterprise is profitable since BCR is greater than 1. The result also revealed that feed cost was the most expensive resource. It was recommended that feed cost should be reduced through the process of substituting feed with locally available by products. Better marketing channels should be established for increased sales of pork.
Destination marketing organizations (DMO) established in mountain tourist resorts and regions – a solution for mountain tourism development
B?ltescu, C. A.
Bulletin of the Transilvania University of Brasov. Series V : Economic Sciences , 2011,
Abstract: When a tourist destination succeeds in presenting itself before the potential visitors and companies interested in operating different activities in the area, as single whole, as an integrated ensemble of providers and professionals with a common aim, that of developing in the long run the region, their joint demarches promoting the existent tourist potential, the expected success, for the benefit of all, is easier to achieve and much more reliable. This article aims to highlight the importance and decisive influences of destination marketing organizations, known in the literature as DMOs, as well as the demarches initiated in this respect within the Romanian mountain tourism, with reference to Poiana Bra ov mountain resort.
Challenges and Opportunities Facing Brand Management in the Lodging Industry
B?ltescu C. A.
Bulletin of the Transilvania University of Brasov. Series V : Economic Sciences , 2009,
Abstract: Brands are at the heart of marketing and business strategy. If a company’s offer is perceived to be the same as those of the competitors, then consumers will be indifferent and will choose the cheapest or most accessible. The purpose of marketing is to create a preference for the company’s brand. If customers perceive one brand as superior, they will prefer it and pay more for it. Successful brands create wealth by attracting and retaining customers. When a company creates this type of customer preference and loyalty, it can build a strong market share, maintain good price levels and generate strong cash flows. The notion that a hotel’s brand contributes significantly to the property’s market value is supported by an analysis of nearly eleven hundred hotel transactions over the past fifteen years.
The Behcet’s Disease: An Uncommon Cause of Venous Thrombosis in the Tropical Area: 10 Cases  [PDF]
B. C. Fall, A. C. Ndao, S. Sarr, M. Dieng, S. Ndongo, A. Leye, A. Pouye
Open Journal of Internal Medicine (OJIM) , 2017, DOI: 10.4236/ojim.2017.74020
Abstract: Introduction: The Behcet’s disease is deemed to be scarce in Black Africa where data are still scattered. The purpose of our study is to describe the epidemiological, clinical, paraclinic and evolutive particularities of the patients whose presenting symptoms of the Behcet’s diseases were a venous thrombosis. Patients and Methods: It was a descriptive, multicenter, and cross-sectional study lasting 15 months. We brought together all the cases of the Behcet’s disease revealed by venous thrombosis. The diagnosis was based on clinical criteria of the international group of study of the Behcet’s disease in 2007. Results: We have grouped 10 revealing thrombosis cases of the Behcet’s diseases during our study period. The average age was 34. The average wait period between the appearances of the early symptoms and the diagnosis of the very disease was 30 months. The admission motives were the abdominal pain (2 cases), a thrombophlebitis of the lower limb (2 cases), headaches (1 case), coma (1 case), a thrombophlebitis of the upper limb (3 cases). The thrombotic symptoms were exclusively venous-located. The seats of the thrombosis were the vena cava superior in 30% of the cases, the vena cava inferior in 20% of the cases, the veins of the lower limb in 20% of the cases, the cerebral vein in 20% of the cases, and the auxiliary vein in 10% of the cases. The treatment of the deep venous thrombosis consisted in all the cases of an effective anticoagulation associated with the colchicine. Primarily, the corticotherapy with a high dose was used in all the patients. One of them in the comatose stage, manifesting both cerebral thrombophlebitis and aseptic meningitis, had died. Conclusion: Behcet’s disease is a disease of the young adult, but it must be evoked even in old age, with a view to appropriate management, in order to avoid the complications of the disease. Although it is rare in our regions, it should be sought in the etiological assessment of venous thrombosis whatever the location.
Data Mining in Biomedicine: Current Applications and Further Directions for Research  [PDF]
Journal of Software Engineering and Applications (JSEA) , 2009, DOI: 10.4236/jsea.2009.23022
Abstract: Data mining is the process of finding the patterns, associations or relationships among data using different analytical techniques involving the creation of a model and the concluded result will become useful information or knowledge. The advancement of the new medical deceives and the database management systems create a huge number of data-bases in the biomedicine world. Establishing a methodology for knowledge discovery and management of the large amounts of heterogeneous data has become a major priority of research. This paper introduces some basic data mining techniques, unsupervised learning and supervising learning, and reviews the application of data mining in biomedicine. Applications of the multimedia mining, including text, image, video and web mining are discussed. The key issues faced by the computing professional, medical doctors and clinicians are highlighted. We also state some foreseeable future developments in the field. Although extracting useful information from raw biomedical data is a challenging task, data mining is still a good area of scientific study and remains a promising and rich field for research.
Application of Photo-Fenton Process for the Treatment of Kraft Pulp Mill Effluent  [PDF]
M. D. Rabelo, C. R. Bellato, C. M. Silva, R. B. Ruy, C. A. B. da Silva, W. G. Nunes
Advances in Chemical Engineering and Science (ACES) , 2014, DOI: 10.4236/aces.2014.44050
Abstract: The present work evaluated the use of photo-Fenton process for the treatment of kraft pulp mill effluent. The photo-Fenton best operating conditions, such as pH, concentration, and H2O2: Fe2+ ratio were evaluated. The efficiency of the treatment was measured by COD (chemical oxygen demand) removal. The results showed that the optimum pH for the photo-Fenton process was equal to 3. The increase in H2O2 application resulted in an efficiency increase of the photo-Fenton process, although this was not a directly proportional relation. For most cases, the H2O2: Fe2+ proportion of 100:1 yielded the best results for COD removal. Solar radiation was more efficient than artificial UV to the COD removal. During the treatment the organic matter of the effluent was more oxidized than mineralized, showing a higher removal of COD than BOD (biochemical oxygen demand) and TOC (total organic carbon), respectively. So, photo-Fenton process increased the BOD/ COD ration but decreased the BOD/TOC ratio.
Gastric Neoplasia during Anti-TNF Therapy for Crohn’s Disease: Casual Event?  [PDF]
F. M. L. Fortes, B. C. Silva, B. C. Silva, M. C. Lyra, A. M. Pimentel, G. O. Santana
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.68081
Abstract: The increase risk of cancer development in patients with inflammatory intestinal disease (IBD) has already studied for decades. The anti-TNF therapy has changed the treatment strategy of IBD. By using on a larger scale and for a longer time, the anti-TNF raised concern over its potential adverse events. A male Crohn’s disease (CD) patient, 55 years old, diagnosed for nine years, treated with infliximab for 6 years. In 2011, he underwent a nupper endoscopy (UE) which showed flat erosive gastritis with moderate intensity in antrum, gastric polyps and gastric erosion. Pathological examination revealed a chronic gastritis in erosive activity and search for Helicobacter pylori resulted positive. In May 2014, the patient was asymptomatic, when it held UE, which showed suggestive lesion of early gastric cancer, measuring 1.5 cm and search for Helicobacter pylori negative. Histopathological exams confirmed the adenocarcinoma. The patient underwent to a laparoscopic surgery (total gastrectomy with lymphadenectomy and reconstruction Roux-en-Y). Risk factors for the development of gastric cancer in general population are already well defined. However studying a possible association among CD and the different therapeutic modalities used in the treatment of this disease with gastric cancer appearance is important to set specific assessment strategies, prevention and follow-up. While there is no consensus on a proper monitoring for gastric cancer prevention in these patients, individualized conduct, taking into account individual characteristics, family record and other risk factors, should be adopted to avoid unfavorable outcomes in CD patients.
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