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Search Results: 1 - 10 of 461787 matches for " A. Bougouma "
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Hepatitis B Surface Antigen Should Not Be the Only Sought Marker to Distinguish Blood Donors towards Hepatitis B Virus Infection in High Prevalence Area  [PDF]
K. S. Somda, A. K. Sermé, A. Coulibaly, K. Cissé, A. Sawadogo, A. R. Sombié, A. Bougouma
Open Journal of Gastroenterology (OJGas) , 2016, DOI: 10.4236/ojgas.2016.611039
Abstract: Since its discovery by Blumberg in 1965, the hepatitis B surface antigen (HBsAg) is used as the fingerprint of hepatitis B infection. Occult hepatitis B infection (OBI) is defined by a viral replication (DNA detectable) in the absence of HBsAg. Burkina Faso is a high endemic area where the prevalence is higher than 14%. At the National Center for Blood Transfusion (NCBT) of Ouagadougou, HBsAg is the only sought marker used to distinguish donors towards Hepatitis B Virus (HBV). Acceptation of blood donation is based specifically on the absence of HBsAg, which exposes to the risk of HBV transmission during transfusion. The goal of this study is to evaluate this risk by determining the prevalence of OBI in blood donors. Patients and Methods: ?It was a five-month prospective study on blood donations collected from January to May 2016. The HBc antibody has been sought in the serums of negative HBsAg donors. The measure of B DNA by Real Time PCR (polymerase chain reaction) and that of antibodies anti-HBs have been proposed to anti-HBc positive donors. Abdominal ultrasound, the transaminases, prothrombin level, alphafeto-proteins, hepatic fibrosis have been proposed to donors who were detectable for the DNA. Sociodemographic parameters have been collected. The test costs were borne by donors who were recalled by phone to adhere to the study. Results: Among 1980 negative donors HBsAg, 872 (44%) were positive for anti-HBc. 160 on 872 donors were received for consultation, among which 76 (76/160) were able to realise DNA which was detectable in 25 donors on 76, thus a prevalence of 32.8%. The mean value of DNA was 953 IU/ml. Physical examination and hepatic ultrasounds were normal except a case where hepatic steatosis was found. The biologic standard hepatic results were in normal range. None of the patient was able to realise hepatic fibrosis evaluation. A case of co-infection HIV/OBI was noted. Conclusion: This study shows that in Burkina, almost half of blood bags transfused are anti-HBc positive and around one third (32.8%) probably have HBV DNA. This poses a potential risk of contamination for non-immunized recipient.
Peptic Ulcer Disease in CHUYO  [PDF]
A. Coulibaly, A. K. Sermé, H. Godonou, K. S. Somda, K. Cissé, Sia Romond, Kafando Roch, R. A. Sombié, A. Bougouma
Open Journal of Gastroenterology (OJGas) , 2016, DOI: 10.4236/ojgas.2016.611038
Abstract: Background: Prevalence of Peptic Ulcer Disease (PUD) is decreasing in developed countries since the use of the treatments for eradication of Helicobacter pylori. Objectives: To revalue the sociodemographic, clinical and evolutionary aspects of the PUD among hospitalized patients in CHUYO. Methodology: This prospective study is related to 65 files of patients hospitalized in hepato-gastroenterology and general surgical services of the CHUYO between March 1st and August 31st, 2015. Results: Hospital utilization rate was 6.59%. The average age of patients was 40.6 years with extremes of 17 and 80 years. The sex ratio was 9.8. The location of the ulcer was 69.23% in stomach. A notion of taking aggressive gastrointestinal products was found in 62 patients (95.4%). The clinical picture was represented by diffuse abdominal pain (76.92%), peritoneal irritation syndrome (64.61%) and epigastric pain (56.92%), anemia (23.07%). Gastric perforations (64.61%) and gastrointestinal bleeding (12.30%) were the main complications. Consumption of non-steroidal anti-inflammatory drugs (NSAIDs) was found in 81.5% of cases. The management was medical and/or surgical with an overall mortality rate of 7.7%. Conclusion: The PUD rate decreased from 10.12% to 6.59% in 5 years. The complications are dominated by stomach perforations. They are relative increase and seem related to NSAIDs. Better management of this disease requires awareness of the population to self-medication.
Epidémie de choléra au Burkina Faso en 2005: aspects épidémiologiques et diagnostiques
CG Kyelem, A Bougouma, RS Thiombiano, IA Salou-Kagoné, L Sangaré, R Ouédraogo
Pan African Medical Journal , 2011,
Abstract: Introduction : L’objectif de cette étude était de décrire les aspects épidémiologiques et diagnostiques de l’épidémie de choléra au Burkina Faso en 2005. Méthodes : Etude rétrospective, d’ao t à octobre 2005. Elle a concerné dix districts sanitaires du Burkina Faso. A été inclus dans l’étude, tout patient présentant un syndrome cholériforme, admis dans les différentes formations sanitaires dont la coproculture s’est révélée positive à Vibrio cholerae. Résultats : Au cours cette épidémie, 1050 cas de diarrhées cholériformes ont été notifiés par l’ensemble des structures sanitaires du pays. Vibrio cholerae a été identifié à l’examen bactériologique des selles de 121 patients (17,2%), constituant notre population d’étude. Les hommes étaient majoritaires (57%). La moyenne d’age était de 30 ans. Les femmes au foyer (24%) et les sujets non scolarisés (62,8%) représentaient les couches sociales les plus touchées. Les forages ont été la source de boisson de 39,7% des patients 72 heures avant le début de la maladie. Tous les patients ont présenté une diarrhée aqueuse. Vibrio cholerae, sérotype Ogawa, responsable de cette épidémie, était résistant au chloramphénicol et au cotrimoxazole dans respectivement 71,7% et 38,3% des cas. Ni le cas index, ni la source initiale de contamination n’ont pu être identifiés. La létalité de notre échantillon était de 3,5%. Conclusion : Cette épidémie a relancé la question de l’hygiène et mis à nu le problème de ces villes où la croissance démographique galopante est en inadéquation avec le degré d’urbanisation.
Prevention of Mother-to-Child Transmission of Hepatitis B in the Urban District Health Baskuy Burkina Faso  [PDF]
Alice Nanelin Guingané, Nicolas Meda, Roger Sombié, Christiane Béré/Somé, Lydie Sia, Rose Ido/Da, Issa Guiraud, Alain Bougouma
Open Journal of Gastroenterology (OJGas) , 2016, DOI: 10.4236/ojgas.2016.66023
Abstract: Few studies have been conducted on the epidemiology in pregnancy in sub-Saharan Africa. This study aimed to improve the care of pregnant women infected with hepatitis B virus (VHB) and their newborns in the urban district health. Method: This study was conducted from 01/09/2014 to 01/09/2015. Study involved three types of data collection: a collection of data from health facilities involved in the project; repeated cross-sectional survey among health personnel; a pros- pective study of pregnant women identified positive for HBsAg and followed at the University Hospital Yalgado Ouédraogo (CHU-YO). Knowledge assessment was made among health staff and pregnant women using a knowledge score. Construction of the score came after a factorial analysis of multiple correspondences on population health workers surveyed in the first round (N = 119) on one hand and all pregnant women (N = 266) on the other hand. This had identified among the 79/19 questions, those that discriminated best knowledge of paramedics and pregnant women. For pregnant women, this score was then dichotomized from the center and logistic regression was performed to determine the sociodemographic, medical and obstetric characteristics that influenced it (p value < 005). Results: Health staff had been surveyed twice (N = 119/100). In general, the level of knowledge was good on targeted knowledge, both before and after training. No health worker routinely offered screening for hepatitis B among pregnant women attending antenatal clinics. Altogether 266 pregnant women HBsAg-positive were referred and followed CHU-YO. Half of the patients had a score lower than 2/17. Univariate analysis showed that variables such as education level influenced significantly the level of knowledge. Women with higher levels of education had a higher level of knowledge about the disease, compared to those of primary level [OR = 1.63; [1.34 to 1.99], p value < 0,001]. Newborns during the study period numbered 128 and the vaccine was made in the first 24 hours of life for 83.6% of them. Conclusion: routine screening for infection with VHB during pregnancy and improved knowledge of mothers is strongly reco- mmended in Burkina Faso.
The structure of niobium-doped MoSe2 and WSe2
Moussa Bougouma,Boubié Guel,Tiriana Segato,Jean B. Legma
Bulletin of the Chemical Society of Ethiopia , 2008,
Abstract: Polycrystalline niobium-doped molybdenum and tungsten diselenides were synthesized in silicatubes sealed under secondary vacuum. They were characterized by scanning electron microscopy, electrondiffraction, X-ray diffraction, chemical composition and EDX analyses. The morphology of niobium-dopedmolybdenum solid solutions was shown to depend strongly on the conditions of synthesis, whereas the structuralcharacterization did not.
Treatment of HBeAg-Negative Chronic Hepatitis B Patients with Nucleos(t)ide Analogues in Burkina Faso  [PDF]
Kounpiélimé Sosthène Somda, Abdel Karim Sermé, Aboubacar Coulibaly, Steve Léonce Zoungrana, Inès Compaoré, Serges Kouamou, Damien Ouattara, Roger Sombié, Alain Bougouma
Open Journal of Gastroenterology (OJGas) , 2016, DOI: 10.4236/ojgas.2016.612041
Abstract: The treatment of chronic hepatitis B (CHB) has increased significantly in recent years. In patients affected by HBeAg-negative CHB, it is necessary to distinguish the inactive carriers (low viral DNA < 2000 IU/mL, normal ALT, histological lesions absent or minimal) who does not need treatment, and patients suffering from active CHB (DNA > 2000 IU/ml, high transaminases or fluctuating, significant fibrosis and/or necro-inflammatory activity > 1) who must be treated. The main purpose of treatment is to obtain a long-lasting viral suppression to improve the histological lesions and reduce the risk of evolution towards cirrhosis, liver failure and hepatocellular carcinoma (HCC). It about an indefinite treatment (unless HBsAg seroclearance) expensive and often inaccessible for the majority of our patients. Our study aimed to report the results of four years follow-up of HBeAg-negative patients treated by Nucleos(t)ide analogues (NAs) in Ouagadougou (Burkina Faso). It was a clinical observational study with 133 patients including 95 men; the average age was 41.2 years, completing the criteria of treatment. One hundred and twelve patients were treated by tenofovir (TDF), fourteen by lamivudine and seven co-infected HIV/HBV patients by Atripla® (combination TDF, Emtricitabine and Efavirenz). Virological and biochemical responses were respectively 100% and 94% after 4 years. The rate of HBsAg seroclearance was 1.5%. Twelve of fourteen patients (85.7%) had lamivudine resistance and no cases of resistance in the TDF and Atripla® groups. One co-infected patient developed HCC during treatment. Among patients treated by TDF, two cases of hypophosphatemia were noticed and no case of kidney failure. The treatment of CHB is certainly progressing; updated guidelines (EASL, AASLD) exist but should be adapted to the African context.
Symptomatic Extra-Dural Arachnoid Cyst  [PDF]
Habib Abdoul Karim Ouiminga, Magatte Gaye, Cheik Tidiane Hafiz Bougouma, Raphael Marie Kabore, Désiré Harouna Sankara, Oumar Salia, Souleymane Ouattara, Yannick Canton Kessely
World Journal of Neuroscience (WJNS) , 2018, DOI: 10.4236/wjns.2018.82017
Abstract: Objective: The aim of this study is to report a case of arachnoid cyst due to mass effect on the thoracic marrow. Observation: A 15-year-old patient was admitted to our institution and complaining of high back pain. Three months before he developed progressive and occasional back pain with thoracic irradiation in hemi-belt, increased by the dorsal decubitus. Neurological examination revealed a spasmodic paraplegia. The muscular strength was quoted as 2 to the left and 3 to the right on a scale of 5. Magnetic resonance imaging (MRI) revealed and extradural cyst located to the dorsal spinal cord. The ablation of a voluminous translucent cyst was achieved after a vast decompressive laminectomy from the sixth to the eighth thoracic vertebra. The dural communication with the cyst was stitched. After surgery, the pain has disappeared and the neurological recovery was progressive over a period of 21 days. The diagnosis of arachnoid cyst was confirmed by histological examination. Conclusion: The extradural thoracic arachnoid cyst is a rare affection of good forecast. In the symptomatic form, the surgery as soon as possible remains the solution. The MRI keeps all its interest for the diagnostic orientation and the therapeutic strategy.
Evaluation of Mass Drug Administration Impact on Transmission of Lymphatic Filariasis in 13 Sanitary Districts in Burkina Faso  [PDF]
Nomtondo Amina Ouedraogo, Sidnoma Muriel Ouedraogo, Gilbert Patrice Tapsoba, W. Roland Bougma, Mamadou Serme, Apollinaire Kima, Nadia Kaboret, Ibrahim Sangare, Clarisse Bougouma, Fran?ois Drabo
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2018, DOI: 10.4236/jcdsa.2018.84020
Abstract: Introduction: Lymphatic filariasis (LF) is one of the neglected tropical diseases targeted for elimination as a public health issue in the world by 2020. To achieve this goal, one of the strategies is interruption of transmission using chemotherapy (mass drug administration). Burkina Faso in west Africa, an endemic country, has endorsed this resolution. In 2000, all Sanitary Districts (SD) in the country were endemic, and then a national elimination program has made it possible to stop mass treatment in 45 out of 70 SD over 12 years. Sixteen years later, 13 other SD were reeligible for Transmission Assessment Surveys (TAS). This study aimed to determine the current level of the Mass drugs Administration (MDA) impact indicators in these 13 targeted SD in order to decide whether we need to continue MDA. Method: It was a descriptive study that took place from June to September 2017 in 13 SD regrouped into 7 Evaluation Units (EU). The population of the study was 6 to 7 years old children. The community-based cluster survey method was used. The diagnostic test used to detect Wuchereria bancroftis circulating antigen (W. bancrofti) is the
The structure of niobium-doped MoSe2 and WSe2
Moussa Bougouma, Boubié Guel, Tiriana Segato, Jean B. Legma, Marie-Paule Delplancke Ogletree
Bulletin of the Chemical Society of Ethiopia , 2008,
Abstract: Polycrystalline niobium-doped molybdenum and tungsten diselenides were synthesized in silica tubes sealed under secondary vacuum. They were characterized by scanning electron microscopy, electron diffraction, X-ray diffraction, chemical composition and EDX analyses. The morphology of niobium-doped molybdenum solid solutions was shown to depend strongly on the conditions of synthesis, whereas the structural characterization did not. KEY WORDS: Polycrystalline niobium-doped molybdenum and tungsten diselenide solid solutions, Doped powders diselenides, Mo1-xNbxSe2, W1-xNbxSe2, SEM, X-ray diffraction, Electron diffraction Bull. Chem. Soc. Ethiop. 2008, 22(2), 225-236.
Epidémie de choléra au Burkina Faso en 2005: aspects épidémiologiques et diagnostiques
Carole Gilberte Kyelem,Alain Bougouma,Rigobert Sankardia Thiombiano,Ida Adeline Salou-Kagoné
Pan African Medical Journal , 2011,
Abstract: INTRODUCTION: L’objectif de cette étude était de décrire les aspects épidémiologiques et diagnostiques de l’épidémie de choléra au Burkina Faso en 2005. METHODES: Etude rétrospective, d’ao t à octobre 2005. Elle a concerné dix districts sanitaires du Burkina Faso. A été inclus dans l’étude, tout patient présentant un syndrome cholériforme, admis dans les différentes formations sanitaires dont la coproculture s’est révélée positive à Vibrio cholerae. RESULTATS: Au cours cette épidémie, 1050 cas de diarrhées cholériformes ont été notifiés par l’ensemble des structures sanitaires du pays. Vibrio cholerae a été identifié à l’examen bactériologique des selles de 121 patients (17,2%), constituant notre population d’étude. Les hommes étaient majoritaires (57%). La moyenne d’age était de 30 ans. Les femmes au foyer (24%) et les sujets non scolarisés (62,8%) représentaient les couches sociales les plus touchées. Les forages ont été la source de boisson de 39,7% des patients 72 heures avant le début de la maladie. Tous les patients ont présenté une diarrhée aqueuse. Vibrio cholerae, sérotype Ogawa, responsable de cette épidémie, était résistant au chloramphénicol et au cotrimoxazole dans respectivement 71,7% et 38,3% des cas. Ni le cas index, ni la source initiale de contamination n’ont pu être identifiés. La létalité de notre échantillon était de 3,5%. CONCLUSION: Cette épidémie a relancé la question de l’hygiène et mis à nu le problème de ces villes ou la croissance démographique galopante est en inadéquation avec le degré d’urbanisation
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