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Search Results: 1 - 1 of 1 matches for " (-)-robidanol "
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Flavonoid from Intsia palembanica as Skin Whitening Agent
I. Batubara,L.K. Darusman,T. Mitsunaga,H. Aoki
Journal of Biological Sciences , 2011,
Abstract: This study aims to obtain active compounds from Intsia palembanica with skin whitening activity. I. palembanica methanol extracts were separated using chromatography techniques and yielded 3 flavanols. Isolated compounds along with 6 other flavonoid compounds were analyzed for tyrosinase inhibitory activity and inhibition of melanin cell growth in B16 cell. The results showed that (-)-robidanol is the most potent tyrosinase inhibitor (IC50 monophenolase 8.7 M; diphenolase 26.6 M) and inhibit melanin synthesis 46.2% compared to control (at 100 M). In conclusion, (-)-robidanol is the best compound as a whitening agent.
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