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Search Results: 1 - 10 of 2365 matches for " ?ükrü Kumsar "
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Changes in Electrocardiogram Findings during Treatment with Gonadotropin-Releasing Hormone Agonist and Surgical Castration for Prostate Carcinoma  [PDF]
Hasan Sa?lam, Akif ?akar, Osman K?se, ?ükrü Kumsar, Salih Budak, Serbülent G?khan Beyaz, ?ztu? Adsan
Open Journal of Urology (OJU) , 2012, DOI: 10.4236/oju.2012.223029
Abstract: Purpose: To investigate electrocardiogram (ECG) changes after complete androgen blockade (CAB) achieved by either surgical or medical castration and compare the outcomes of the groups. Methods: Sixty-three consecutive men (between 58 - 86 years of age) requiring CAB for prostate cancer were enrolled in the study. Patients with diabetes mellitus, an additional malignancy, coronary heart disease, atrial fibrillation, heart failure or a medical history of cardiac event in the last 12 months were excluded from the study. Additionally, those who were taking medicine affecting heart rate were excluded. The participants were divided into two groups according to their modality of castration. The first group consisted of 35 patients who received bilateral orchiectomy plus anti-androgen medication. The second group contained 28 patients who accepted gonadotropin-releasing hormone (GnRH) plus anti-androgen therapy. After complete examinations and biochemical tests, the ECG leads of the patients were obtained conveniently. This was then repeated at three- and six-month visits. ECG findings (including heart rate, PR, QRS, QT, corrected QT (QTc) intervals and QT dispersion (QTd)) were recorded and analysed statistically. The groups were then compared in terms of pre- and post-treatment ECG outcomes. Results: Both groups revealed similarly lower heart rate and prolonged PR, QRS, QT, corrected QTc and QTd by the end of six months. By the end of three months, all variables had changed significantly in the orchiectomy group, whereas in the GnRH group, they had not. Conclusion: CAB may result in lower heart rate and prolonged QT, a condition associated with fatal cardiac arrhythmia and sudden death. Therefore, patients receiving CAB should be monitored closely for cardiac adverse effects.
Youth consultation and health centers
?ükrü
Turk Pediatri Ar?ivi , 2011,
Abstract: In 2005, a youth consultation and health center has been established by cooperation of Turkish Ministry of Health, UNFPA and UN CEF. Two doctors, 2 psychologists and 1 dietician is serving in our center. In this center, we serve for diagnosis and treatment of adolescents and when needed reference to other institutions. Consultation on physical-sexual development, psycho-social development, personal hygiene, nutrition, physical exercise, smoking and alcohol use, secure behaviors, secure sexual life and psychological problems is also given. Adolescents generally apply to the center for reasons like conflict with parents, low academic performance, aggression, being overweight, computer addiction, conflict with siblings and being short. As a result of our experience, we think that in order to develop adolescent health services, all health centers should be organized as “youth friendly”. (Turk Arch Ped 2011; 46 Suppl: 135-7)
Accordion Manoeuvre with Ilizarov Frame over Nail in Situ in a Case of Infected Non-Union of Femur: Discussion on Strategies: A Case Report  [PDF]
Ranjit Kr. Baruah
Open Journal of Orthopedics (OJO) , 2014, DOI: 10.4236/ojo.2014.47030
Abstract: Quiescent Type of H. Rosen & Stage 2 of C.L. Romano et al. for Infected Non Union of Femur after K-nailing (Küntscher nailing) require no debridement & removal of nail and therefore can be treated by a single stage procedure. There are a few reports of treating aseptic non-union of femur by compression alone or compression distraction over nail by Ilizarov Technique. However, no case of Infected Non-Union femur being treated by Accordion Manoeuvre with Ilizarov over nail in situ (i.e. without exchange nailing) has been reported so far. Here, we are reporting a case of Infected Non-Union following K-nailing for a fracture shaft of femur in a 15-year-old female, who was treated by this technique as a single stage procedure. An Ilizarov frame was mounted on the femur with nail in situ followed by Accordion Manoeuvre. The fracture was healed in 5.6 months with two cycles of Accordion Manoeuvre followed by rhythmic compression. There was no recurrence of infection.
Constraining Forces Causing the Meissner Effect  [PDF]
Ekkehard Krüger
Journal of Modern Physics (JMP) , 2017, DOI: 10.4236/jmp.2017.88074
Abstract: As shown in former papers, the nonadiabatic Heisenberg model presents a novel mechanism of Cooper pair formation which is not the result of an attractive electron-electron interaction but can be described in terms of quantum mechanical constraining forces. This mechanism operates in narrow, roughly half-filled superconducting bands of special symmetry and is evidently responsible for the formation of Cooper pairs in all superconductors. Here we consider this new mechanism within an outer magnetic field. We show that in the magnetic field the constraining forces produce Cooper pairs of non-vanishing total momentum with the consequence that an electric current flows within the superconductor. This current satisfies the London equations and, consequently, leads to the Meissner effect. This theoretical result is confirmed by the experimental observation that all superconductors, whether conventional or unconventional, exhibit the Meissner effect.
An Analysis of Structural and Optical Properties Undoped ZnS and Doped (with Mn, Ni) ZnS Nano Particles  [PDF]
Apurba Kr. Das, Apurba Kr. Buzarbaruah, Santanu Bardaloi
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.47137
Abstract:

The behavior of nano-particles finds a wide application in opto-electronic and semi-conductor devices. ZnS nano-crystals were grown into poly-vinyl alcohol matrix by chemical route at different weight percentage. Optical properties of both un-doped and doped with ZnS nano-crystalline compounds were studied. The nano structure was characterized with the help of X-ray diffraction (XRD) and Hi-resolution Transmission Electron Microscopy (HRTEM). Surface morphology was studied with the help of Scanning Electron Microscopy (SEM). The average particle sizes of ZnS, ZnS-Ni and ZnS-Mn were found to be 6.51, 7.3 and 12 nm respectively in TEM and that obtained from Debye-Scherrer formula is about 2.3 and 2.5 nm for undoped and doped ZnS respectively. Peak of Photo-luminescence (PL) emission spectra was obtained at 375 nm at room temperature and another peak at 433 nm for Ni. Again the peak of Photo-luminescence (PL) emission spectra was obtained at 334 nm at room temperature for Mn, Mn dependant emission was found at 580 nm. These data showed successful doping. PL studies also confirmed presence of dopant in the nano crystallites. Optical absorption studies were carried out with UV-VIS Spectrophotometer and showed a strong absorbance at wavelength 400 nm with a tendency towards blue shift. Selected area electron diffraction (SAED) shows a set of four well defined rings corresponding to diffraction from different planes of the nano crystallites. HRTEM image showed a well crystalline ZnS doped with Ni and Mn. Both Raman spectra and XRD studies confirmed the well crystalline states of ZnS.

Optimization of Tribological Performance of Al-6061T6-15% SiCp-15% Al2O3 Hybrid Metal Matrix Composites Using Taguchi Method & Grey Relational Analysis  [PDF]
Ashok Kr. Mishra, Vinod Kumar, Rajesh Kr. Srivastava
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2014, DOI: 10.4236/jmmce.2014.24040
Abstract: In this investigation, optimization of tribological performance parameters of Al-6061T6 alloy reinforced with SiC (15% by weight) and Al2O3 (15% by weight) particulates having particle size of 37 μm each has been presented. The wear and frictional properties of the hybrid metal matrix composites have been studied by performing dry sliding wear test using pin-on-disc wear tester. A L27 orthogonal array is selected for the analysis of the data. From the test results it is observed that sliding distance has the significant contribution in controlling the friction and wear behaviour of hybrid composites. A confirmation test is also carried out to verify the accuracy of the results obtained through the optimization. In addition an optical micrograph test is also performed on the wear tracks to study the wear mechanism.
LDM (Layered Deployment Model): A Novel Framework to Deploy Sensors in an Irregular Terrain  [PDF]
Chandan Kr. Bhattacharyya, Swapan Bhattacharya
Wireless Sensor Network (WSN) , 2011, DOI: 10.4236/wsn.2011.36022
Abstract: Deployment of sensors in any irregular terrain with 100% coverage and connectivity is a challenging issue in the field of Wireless Sensor Networks. Traditional deployments often assume homogeneous environments, which ignore the effect of terrain profile as well as the in-network obstacles situated randomly like buildings, trees, roads and so on. Proper deployment of sensors in such irregular region and its corresponding routing is one of the most fundamental challenges of Wireless Sensor Networks. In this work, we have considered that the terrain is irregular in shape and there may be obstacles within the terrain in any random position with any random shape, which is the reality in real world. With this novel framework, we have shown that an opti-mum deployment can be achieved in such irregular terrain without compromising coverage as well as con-nectivity between the sensor nodes for effective routing.
Influence of Pre-Impregnation Treatment on Bamboo Reinforced Epoxy/UPE Resin Composites  [PDF]
Pradeep Kr. Kushwaha, Rakesh Kumar
Open Journal of Composite Materials (OJCM) , 2012, DOI: 10.4236/ojcm.2012.24017
Abstract: Bamboo based biocomposites were made with woven bamboo mats and epoxy/unsaturated polyester (UPE) resins. The effects of pre-impregnation on the mechanical and water resistant properties of composites were studied. An alkaline treatment was used to enhance the fiber wetting so as to achieve complete pre-impregnation with epoxy and unsaturated polyester resins. A combined treatment of alkali and dilute epoxy/polyester gives the best result. Bending strength, modulus of elasticity, tensile strength, tensile modulus, impact strength, water absorption were evaluated and compared for all composites. Scanning electron microscopy (SEM) studies of the composites tensile fracture surface also indicated that there is an improved adhesion between fiber and matrix. The mechanical as well as water resistant properties of the biocomposites improved after pre-impregnation treatment.
Stress and Strain Accumulation Due to a Long Dip-Slip Fault Movement in an Elastic-Layer over a Viscoelastic Half Space Model of the Lithosphere-Asthenosphere System  [PDF]
Sanjay Sen, Subrata Kr. Debnath
International Journal of Geosciences (IJG) , 2013, DOI: 10.4236/ijg.2013.43050
Abstract:

Most of the earthquake faults in North-East India, China, mid Atlantic-ridge, the Pacific seismic belt and Japan are found to be predominantly dip-slip in nature. In the present paper a dip-slip fault is taken situated in an elastic layer over a viscoelastic half space representing the lithosphere-asthenosphere system. A movement of the dip-slip nature across the fault occurs when the accumulated stress due to various tectonic reasons e.g. mantle convection etc., exceeds the local friction and cohesive forces across the fault. The movement is assumed to be slipping in nature, expressions for displacements, stresses and strains are obtained by solving associated boundary value problem with the help of integral transformation and Green’s function method and a suitable numerical methods is used for computation. A detailed study of these expressions may give some ideas about the nature of stress accumulation in the system, which in turn will be helpful in formulating an earthquake prediction programme.

A Liquid Chromatography Assay for the Simultaneous Quantification of Piperacillin and Ciprofloxacin in Human Plasma and Dialysate in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy  [PDF]
Florian Scheer, Irene Kr?mer
International Journal of Analytical Mass Spectrometry and Chromatography (IJAMSC) , 2014, DOI: 10.4236/ijamsc.2014.22005
Abstract:

Piperacillin/tazobactam and ciprofloxacin are often used in combination as initial empiric anti-biotic therapy in critical ill patients. Especially in patients undergoing continuous renal replacement therapy (CRRT) the pharmacokinetics of antimicrobial agents can be highly variable. In order to avoid under- or overdosage of antibiotics therapeutic drug monitoring (TDM) is highly re-commendable. Based on two known HPLC assays for piperacillin a new method in combination with solid phase extraction (SPE) for the simultaneous determination of piperacillin and ciprofloxacin was developed. Method validation was performed according to the EMA guideline on validation of bioanalytical methods. The HPLC column used was a Perfect Bond ODS-HD C18 analytical column (100 mm × 4.6 mm i.d., particle size 5 μm), equipped with a guard column (10 mm × 4.6 mm, particle size 5 μm) containing the same packing material. Detection wavelength was set at 228 nm for piperacillin and benzylpenicillin was used as internal standard (IS). Ciprofloxacin was determined at two wavelengths (280 nm, 315 nm). This newly developed HPLC method in combination with SPE-extraction allows an accurate, precise, specific and efficient determination of piperacillin and ciprofloxacin in biological matrices. Results allow the calculation of all relevant pharmacokinetic data for critically ill patients undergoing CRRT and the optimization of dosing and TDM.

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