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Childhood Accidental Poisoning in Tafila
Hussein A Bataineh,Ahmed M Bataineh
Iranian Journal of Pediatrics , 2007,
Abstract: Objective: To asses the frequency, causes and how to increase the awareness of childhood poisoning. Material & Methods: A retrospective study of childhood accidental poisoning was conducted in Tafila Prince Zeid Hospital (PZH) by reviewing the files of 134 children admitted with accidental poisoning in 2003-2005. Findings: This study showed that accidental poisoning was frequent but morbidity was low and there were no deaths. Analgesics and antihistamines were the most frequently ingested drugs. Conclusion: The frequency of accidental poisoning is common in Tafila. Household chemicals and medication were the predominant. So, that merits the introduction of a public awareness campaign and increased use of child-resistant containers is important preventive measures that deserve more attention.
The spectrum of accidental childhood poisoning in the Caribbean
Martin,Thomas C.; Brinkman,William;
Revista Panamericana de Salud Pública , 2002, DOI: 10.1590/S1020-49892002001100004
Abstract: objective. to assess accidental poisoning in children in the caribbean country of antigua and barbuda, including the incidence, the types of substances ingested, the age of the children involved, and the clinical outcomes. the results from antigua and barbuda were compared with the results of other reports from the english-speaking caribbean and from the united states of america. design and methods. we performed a retrospective review of the charts of all patients less than 13 years old admitted to the children's ward at holberton hospital in antigua for accidental poisoning between march 1989 and march 1999. those data were compared with data from earlier reports from barbados, guyana, jamaica, and the united states of america. results. in antigua and barbuda there were 255 hospital admissions for accidental poisoning among children below 13 years old over that 10-year period. of the 255 ingestions, 115 of them (45%) were in 1-year-old children, 69 (27%) were in 2-year-old children, and 26 (10%) were in 3-year-old children. these proportions in antigua and barbuda are similar to the age patterns seen in the other countries with which we made comparisons. in antigua and barbuda there was an annual average of 26 hospital admissions for poisoning for the roughly 20 000 children below 13 years of age, for a rate of 1.3 per 1 000. in comparing the patterns of childhood poisoning in all the countries we studied, we found that, as economic levels rose, there was a shift in the substances ingested, with hydrocarbon and plant ingestions decreasing and chemical and medication ingestions increasing. conclusions. there is an increasing variety and complexity of poisonous substances ingested as economic conditions improve. this trend would make the establishment of a poison control center for the english-speaking caribbean a logical step.
The spectrum of accidental childhood poisoning in the Caribbean  [cached]
Martin Thomas C.,Brinkman William
Revista Panamericana de Salud Pública , 2002,
Abstract: Objective. To assess accidental poisoning in children in the Caribbean country of Antigua and Barbuda, including the incidence, the types of substances ingested, the age of the children involved, and the clinical outcomes. The results from Antigua and Barbuda were compared with the results of other reports from the English-speaking Caribbean and from the United States of America. Design and Methods. We performed a retrospective review of the charts of all patients less than 13 years old admitted to the Children's Ward at Holberton Hospital in Antigua for accidental poisoning between March 1989 and March 1999. Those data were compared with data from earlier reports from Barbados, Guyana, Jamaica, and the United States of America. Results. In Antigua and Barbuda there were 255 hospital admissions for accidental poisoning among children below 13 years old over that 10-year period. Of the 255 ingestions, 115 of them (45%) were in 1-year-old children, 69 (27%) were in 2-year-old children, and 26 (10%) were in 3-year-old children. These proportions in Antigua and Barbuda are similar to the age patterns seen in the other countries with which we made comparisons. In Antigua and Barbuda there was an annual average of 26 hospital admissions for poisoning for the roughly 20 000 children below 13 years of age, for a rate of 1.3 per 1 000. In comparing the patterns of childhood poisoning in all the countries we studied, we found that, as economic levels rose, there was a shift in the substances ingested, with hydrocarbon and plant ingestions decreasing and chemical and medication ingestions increasing. Conclusions. There is an increasing variety and complexity of poisonous substances ingested as economic conditions improve. This trend would make the establishment of a poison control center for the English-speaking Caribbean a logical step.
Accidental and experimental salinomycin poisoning in rabbits
Peixoto, Paulo Vargas;Nogueira, Vivian Assun??o;Gonzaléz, Alexander Perez;Tokarnia, Carlos Hubinger;Fran?a, Ticiana Nascimento;
Pesquisa Veterinária Brasileira , 2009, DOI: 10.1590/S0100-736X2009000900002
Abstract: an outbreak of salinomycin poisoning in rabbits is described. at least 27 out of 2,000 rabbits reared on a farm died after the coccidiostatic drug sulfaquinoxaline was substituted by salinomycin in the feed. an average of 26.9ppm salinomycin was detected in the ration given to the rabbits. clinical signs included anorexia, apathy and bradykinesia, which progressed to incoordination and recumbency. gross lesions consisted of pale areas in the skeletal muscles. the histopathological findings showed severe necrotic degenerative myopathy in association with infiltration of neutrophils and macrophages. one rabbit exhibited similar alterations in the myocardium. mineralization was observed in the affected skeletal muscles in some cases. in order to verify if the poisoning was due to salinomycin, 20 rabbits were divided into five groups and a ration containing the drug at doses of 10, 25, 50, 75 and 100ppm was given. the administration of doses higher than 50ppm resulted in manifestation of the clinical signs seen in the outbreak of poisoning. it was concluded, that probably an error related to the mixture of salinomycin in the feed was the cause of deaths in the spontaneous outbreak of poisoning on the rabbit farm.
Accidental Potassium Bromate Poisoning Causing Acute Renal Failure  [cached]
Adeleke SI,Asani MO
Online Journal of Health & Allied Sciences , 2009,
Abstract: Accidental poisoning is common in children. Potassium bromate is commonly used additive and raising agent in many edibles especially bread which is a staple food in Nigeria. This communication is that of an unusual case of acute renal failure following accidental ingestion of potassium bromate tablets
An Intentional Poisoning by Lormetazepam in a Patient Treated with Nordiazepam  [PDF]
Phak-Rop Pos Pok, Emilie Berland, Michel Mauras, Magali Valès, Erika Kuhlmann
Forensic Medicine and Anatomy Research (FMAR) , 2014, DOI: 10.4236/fmar.2014.24018
Abstract: A case of suspected poisoning by benzodiazepines is presented in this paper. Toxicological analyses were applied on the blood collected 48 hours after the facts. GC-MS and HPLC-DAD have detected only nordiazepam which was prescribed in the treatment. Therefore, LC-MS/MS has detected lormetazepam and lorazepam (major metabolite of lormetazepam) in addition of nordiazepam. The concentrations of lormetazepam, lorazepam and nordiazepam measured in blood were 6.8, 6.3, and 16.2 ng/mL, respectively. The initial concentration of each drug at the relevant time, has been calculated from these residual concentrations, using an extrapolation approach. According to estimates, only lormetazepam (189 ng/mL) and lorazepam (68 ng/mL), were active at the target moment. A poisoning by lormetazepam was then considered. The more technology we have, the greater chance we have to get an outcome that is favorable to justice.
Accidental carbon monoxide poisoning in our homes  [cached]
Sharma Shruti,Gupta Rahul,Paul Barinder,Puri Sandeep
Indian Journal of Critical Care Medicine , 2009,
Abstract: Carbon monoxide (CO) is a colorless, odorless, tasteless, nonirritating, but significantly toxic gas. It is a product of combustion of organic matter in presence of insufficient oxygen supply. Symptoms of mild poisoning include headaches, vertigo and flu like effects, whereas larger exposures can lead to significant toxicity of the central nervous system (CNS), heart, and even death. We are reporting two cases that presented to us in the winter months of December to January with history, sign, symptoms, and radiological evidence of suspected CO poisoning.
Accidental childhood poisoning in Calabar at the turn of the 20th century
SO Ochigbo, JJ Udoh, OE Antia-Obong
Nigerian Journal of Paediatrics , 2004,
Abstract: Background: Accidental poisoning is a preventable cause of childhood morbidity and mortality. Therefore, knowledge of the common causative agents is necessary in order to create awareness among caregivers towards its prevention. Objectives: To document the pattern of accidental childhood poisoning in Calabar from 1996 to 2000, and to compare the findings with those of a previous study from the same centre. Methods: A retrospective study of cases of poisoning seen at the University of Calabar Teaching Hospital over five years was undertaken. The data extracted from the case files included age, sex, date of admission, poison ingested, home address, social class of parents, duration of admission and outcome. Results: There were 45 cases of accidental childhood poisoning out of 20,539 patients seen; an incidence rate of 2.2 per 1000. Twenty-seven (60 percent) of the cases occurred in subjects aged one to two years. Thirty-three (73.3 percent) were males while 12 (26.7 percent) were females. All the cases were children whose parents were from socio-economic classes IV and V. The commonest poison was kerosene in 26 (57.8 percent) cases, followed by alcohol in 10 (22.2 percent), caustic soda in five (11.1 percent), drugs in three (6.7 percent), and bleach in one (2.2 percent). There was an overall mortality of 20 percent; the mortality rates following caustic soda, kerosene, and alcohol were 100 percent, 11.5 percent and 5.5 percent, respectively. Conclusion: The most common agent of accidental childhood poisoning in Calabar was kerosene, followed by alcohol, while the agent with the highest mortality rate was caustic soda. The most vulnerable age group was the under two-year old. The findings of this study call for intensified health education aimed at creating awareness of the need to store these agents away from the reach of children. Nigerian Journal of Paediatrics Vol. 31(3) 2004: 67-70
Acute Renal Failure following Accidental Potassium Bromate Poisoning: A Case Report
JAO Okeniyi, TA Aladekomo, OA Oyelami
Nigerian Journal of Paediatrics , 2003,
Abstract: Accidental poisoning is common in children. Potassium bromate is a commonly used additive and raising agent in many edibles particularly bread, a staple food worldwide, yet its accidental poisoning has hitherto, not been documented in Nigeria. We report an unusual case of acute renal failure following accidental ingestion of potassium bromate tablets. Key Words: Acute renal failure, Poisoning, Potassium bromate Nigerian Journal of Paediatrics Vol.30(4) 2003: 150-153
Psychopharmacologic medications poisoning by type of incident and sex, Rosario, 1990-99  [PDF]
Piola JC,Prada DB,Cagna V,Evangelista M
RETEL : Revista de Toxicología en Línea , 2003,
Abstract: Objective: to improve the knowledge of the psychopharmacologic medications poisonings by type of incident and sex. We analysed 2358 consuls by psychopharmacologic medications poisonings assisted in the Sertox between January/1990-May/1999 . In the statistical processing of the data chi square of Pearson is used. The groups of psychopharmacologic medications are: a) Tranquillizers (57.8%), b) Mixtures of psychopharmacologic medications (16.3%), cs) Anticonvulsants (8.9%), d) Stimulants (6.8%), e) Hypnotics and sedatives nonbarbiturates (5.7%), f) Antidepressants (3.2%) and g) Barbiturates (1.2%). The 90,7% of 1316 identified tranquilizers, some by trade names, are benzodiazepines. The age and sex vary significantly (p<0.01) according to the type of incident: 67,6% are attempted suicides (80,2% women); the 19,1% accidents (57,4% men); the 6,1% addictions (76,6% men). These data permit us to improve the knowledge on psychopharmacologic medications poisoning in Rosario and know age and sex variations in each type of incident.
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