oalib
Search Results: 1 - 10 of 100 matches for " "
All listed articles are free for downloading (OA Articles)
Page 1 /100
Display every page Item
Effect of Phacoemulsification on Intraocular Pressure Control in Primary Open Angle Glaucoma Previously Treated by Trabeculectomy: A Case-Control Study  [PDF]
Samir Aziz, Nicky Spiers, Jeffrey Jay
Open Journal of Ophthalmology (OJOph) , 2012, DOI: 10.4236/ojoph.2012.22004
Abstract: Purpose: To analyse the effect of phacoemulsification on the control of intraocular pressure in primary open angle glaucoma in patients having phacoemulsification after previous trabeculectomy and compare them with a control group who had trabeculectomy alone. Patients and Methods: Twenty one patients (one eye from each) who had phacoemulsification subsequent to trabeculectomy were identified, and compared with 41 controls. Intraocular pressure, bleb appearance, glaucoma medications, iris manipulation and complications were recorded. Each patient was followed for full 12 months. Failure of control was defined as follows: 1) intraocular pressure >21 mm Hg on medication, or 2) a greater number of glaucoma medications than before phacoemulsification. Results: The post operative change in intraocular pressure in the case group at 12 months was much less than that in the control (p = 0.001). The mean intraocular pressure had changed from 15.3 mm Hg to 14.7 mm Hg. The control group showed an average intraocular pressure reduction of 6 mm Hg at the last visit (p > 0.001). In phacoemulsification group, 19% required 1 or 2 glaucoma medications at one year follow-up vs 19.5% in the control group. In phacoemulsification group, 9.5% showed flattening of a previously formed bleb at the last visit (P < 0.001), compared with 9.7% of controls. Conclusions: The stability of glaucoma control in the first year after phacoemulsification in previously filtered eyes with primary open angle glaucoma is comparable to that of the natural course after trabeculectomy. The study is limited by the small number of cases available.
Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure  [cached]
Lee JW,Lai JS,Yick DW,Yuen CY
Clinical Ophthalmology , 2013,
Abstract: Jacky WY Lee,1 Jimmy SM Lai,1 Doris WF Yick,2 Can YF Yuen21Department of Ophthalmology, University of Hong Kong, 2Department of Ophthalmology, The Caritas Medical Centre, Kowloon West Cluster, Hong Kong, People’s Republic of ChinaBackground: The purpose of this study was to compare the efficacy and safety of argon laser peripheral iridoplasty (ALPI) and systemic intraocular pressure (IOP)-lowering medications in the immediate management of acute phacomorphic angle closure.Methods: Consecutive cases of acute phacomorphic angle closure were randomized to receive ALPI and an intravenous or oral carbonic anhydrase inhibitor as initial treatment. Intravenous mannitol was administered for presenting IOP > 60 mmHg or IOP > 40 mmHg 2 hours posttreatment in both arms.Results: Of 10 consecutive cases, six received medical therapy and four received ALPI. Fifty percent in the medical group and none in the ALPI group required intravenous mannitol. The ALPI group took less time to achieve IOP < 25 mmHg (18.8 ± 7.5 minutes versus 115.0 ± 97.0 minutes, P = 0.001, F test); had a greater IOP reduction within 30 minutes (69.8% ± 7.7% versus 40.9 ± 23.9%, P = 0.03, t-test); and had a consistently smaller post-attack cup to disc ratio (0.50 ± 0.02 versus 0.60 ± 0.20, P = 0.002, F test).Conclusion: ALPI offers greater safety, consistency, and efficacy than systemic IOP-lowering medications as initial treatment for phacomorphic angle closure.Keywords: phacomorphic, glaucoma, argon laser peripheral iridoplasty, medical, intraocular pressure
The Effect of Intraocular Pressure Lowering Medications on the Pressure Spike Associated with Intravitreal Injection  [PDF]
Olya Pokrovskaya, Ian Dooley, Salma Babiker, Catherine Croghan, Claire Hartnett, Anthony Cullinane
Open Journal of Ophthalmology (OJOph) , 2015, DOI: 10.4236/ojoph.2015.54023
Abstract: Aim: This study investigates whether the post intravitreal injection intraocular pressure (IOP) spike is modifiable with the use of prophylactic apraclonidine and dorzolomide. Methods: The study design was a prospective, randomised controlled trial. 80 eyes undergoing intravitreal injection of anti-VEGF agent were studied. A control group (n = 42) received no IOP lowering drops, and a study group (n = 38) received guttae apraclonidine and dorzolamide 30 to 40 minutes before the intravitreal injection. IOP measurements were taken in both groups using the Perkins tonometer at baseline, immediately before and after the injection, 5 minutes post-injection, and 15 minutes post-injection. Results: Mean IOP immediately post injection in the study group was 26.71 mmHg, and in the control group was 32.73. The main outcome measure was the area under the curve (AUC)—reflecting the trend of IOP post injection. The AUC was lower in the study group compared to the control group (Mann-Whitney U test, p = 0.046). Conclusions: The use of prophylactic apraclonidine and dorzolamide is effective in modifying the post-injection IOP spike. IOP lowering prophylaxis may be considered in patients with a high baseline IOP.
Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure
Lee JW, Lai JS, Yick DW, Yuen CY
Clinical Ophthalmology , 2013, DOI: http://dx.doi.org/10.2147/OPTH.S39503
Abstract: rgon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure Original Research (915) Total Article Views Authors: Lee JW, Lai JS, Yick DW, Yuen CY Published Date January 2013 Volume 2013:7 Pages 63 - 69 DOI: http://dx.doi.org/10.2147/OPTH.S39503 Received: 24 October 2012 Accepted: 12 November 2012 Published: 09 January 2013 Jacky WY Lee,1 Jimmy SM Lai,1 Doris WF Yick,2 Can YF Yuen2 1Department of Ophthalmology, University of Hong Kong, 2Department of Ophthalmology, The Caritas Medical Centre, Kowloon West Cluster, Hong Kong, People’s Republic of China Background: The purpose of this study was to compare the efficacy and safety of argon laser peripheral iridoplasty (ALPI) and systemic intraocular pressure (IOP)-lowering medications in the immediate management of acute phacomorphic angle closure. Methods: Consecutive cases of acute phacomorphic angle closure were randomized to receive ALPI and an intravenous or oral carbonic anhydrase inhibitor as initial treatment. Intravenous mannitol was administered for presenting IOP > 60 mmHg or IOP > 40 mmHg 2 hours posttreatment in both arms. Results: Of 10 consecutive cases, six received medical therapy and four received ALPI. Fifty percent in the medical group and none in the ALPI group required intravenous mannitol. The ALPI group took less time to achieve IOP < 25 mmHg (18.8 ± 7.5 minutes versus 115.0 ± 97.0 minutes, P = 0.001, F test); had a greater IOP reduction within 30 minutes (69.8% ± 7.7% versus 40.9 ± 23.9%, P = 0.03, t-test); and had a consistently smaller post-attack cup to disc ratio (0.50 ± 0.02 versus 0.60 ± 0.20, P = 0.002, F test). Conclusion: ALPI offers greater safety, consistency, and efficacy than systemic IOP-lowering medications as initial treatment for phacomorphic angle closure.
God's eyes and the schizophrenic hands: listening to a psychiatric patient
Jardim, Luciane Loss;Dantas, Clarissa R.;Miranda, Fabricio Z.;Banzato, Claudio E.M.;
Revista Latinoamericana de Psicopatologia Fundamental , 2010, DOI: 10.1590/S1415-47142010000400003
Abstract: this article describes the intriguing case of a young female patient first seen in the emergency room and then followed up at the psychiatric outpatient facility of the general hospital at unicamp, brazil. the cooperation that ensued between psychiatrists and a psychoanalyst to reach a psychopathological diagnosis is also presented here. the differential diagnosis is discussed within a psychiatric framework and then contributions from listening to the patient's free associations related to the clarification of her psychopathology are described. the clinical collaboration between psychiatry and psychoanalysis proved effective in this case as a clinical method for approaching the patient.
Relationship between Cognitive Deficits and Self-care Instrumental Activities Daily Living in Schizophrenic Patients in Qom's Psychiatric Ward, 2010  [cached]
V Akbari
Qom University of Medical Sciences Journal , 2012,
Abstract: Background and Objectives: Although schizophrenia disorder is not a cognitive dysfunction, it often results in cognitive deficit. Self-care is a life skill which weakens in neuro-cognitive disorders. Since relationship between cognitive deficits and self-care in schizophrenic patients is not yet known, the survey was done to clarify the relationship between cognitive deficits and self-care instrumental activities daily living in schizophrenic patients. Methods: The present study is of descriptive type, wherein 58 schizophrenic patients of psychiatric ward at Nekoo'ee hospital, Qom, were selected by population sampling. Data collection tools were PASS (for measuring the instrumental skills in daily living activities), and LOTCA-II (for measuring cognitive status). The analysis of the data was done by means of Spearman and Pearson correlation test, showing the significant level of p>0.05. Results: The results showed that between the seven cognitive domains(Orientation, Visual Perception, Spatial perception, Motor praxis, Visuomotor organization, Thinking operations, Attention and Concentration) and the aspects of self-care (independence, safety, quality and process of the task) there exists a significant relationship in schizophrenic patients, p=0.000 Conclusion: The present study displays a significant relationship between cognitive deficits and self-care instrumental activities in schizophrenic patients. Thus, by fortifying and improving the cognitive skills, we can effectively increase proper function in treatment planning of schizophrenic patients.
Hypomania in a Schizophrenic Patient Treated with Modafinil for Clozapine-Induced Sedation
Suzan ?ZER,Ba?aran DEM?R
N?ropsikiyatri Ar?ivi , 2010,
Abstract: Modafinil is used in the treatment of excessive daytime sleepiness associated with several conditions. Modafinil has also been suggested to improve antipsychotic-associated sedation in patients with schizophrenia. Although a small risk of psychosis exacerbation has been reported due to modafinil adjunct treatment, modafinil-induced mania or hypomania has not been described in schizophrenia up to now. Herein, we present a 31-year-old patient diagnosed as having schizophrenia according to DSM-IV-TR, who developed a hypomanic episode with irritability, motor activation and uninterruptible speech soon after adding modafinil to clozapine. In this context, the risks and benefits of adjunct therapy with modafinil in treatment- resistant schizophrenic patients who have been prescribed clozapine will be discussed. (Archives of Neuropsychiatry 2010; 47: 171-3)
Psychoeducational intervention and prevention of relapse among schizophrenic disorders in the Italian community psychiatric network  [cached]
Aguglia Eugenio,Pascolo-Fabrici Elisabetta,Bertossi Francesca,Bassi Mariano
Clinical Practice and Epidemiology in Mental Health , 2007, DOI: 10.1186/1745-0179-3-7
Abstract: Background The lack of compliance is associated with an increased risk of hospitalization and switching or augmentation of therapy when compared with being compliant. A synergy of drug therapy and psychosocial interventions can give more benefits in treatment. Methods A perspective study was conducted on 150 patients with schizophrenia over 15 centers in Italy. The experimental group was treated with drug therapy, traditional psychosocial and psychoeducation for the patients and their families, while the control group received traditional psychosocial and drug intervention over 1 year. Results The experimental group showed a significant statistical improvement (p < 0,05) in almost all the scales that have been assessed (BPRS, SAPS, SANS, SIMPSON-ANGUS SCALE, LANCASHIRE QL SCALE). Significant was the reduction of the number of hospitalizations and of days of hospital stay. Conclusion As it is shown in international literature, psychoeducational intervention with schizophrenic patients and their families can reduce the occurrence of relapse.
Adherence to antihypertensive medications and health outcomes among newly treated hypertensive patients
Luca Degli Esposti, Stefania Saragoni, Silvia Benemei, et al
ClinicoEconomics and Outcomes Research , 2011, DOI: http://dx.doi.org/10.2147/CEOR.S15619
Abstract: dherence to antihypertensive medications and health outcomes among newly treated hypertensive patients Review (4461) Total Article Views Authors: Luca Degli Esposti, Stefania Saragoni, Silvia Benemei, et al Published Date March 2011 Volume 2011:3 Pages 47 - 54 DOI: http://dx.doi.org/10.2147/CEOR.S15619 Luca Degli Esposti1, Stefania Saragoni1, Silvia Benemei3, Paolo Batacchi2, Pierangelo Geppetti3, Mauro Di Bari3, Niccolò Marchionni3, Alessandra Sturani4, Stefano Buda1, Ezio Degli Esposti4 1CliCon S.r.l. Health, Economics and Outcomes Research, Ravenna, Italy; 2Pharmaceutical Policy Department, Local Health Unit of Florence, Florence, Italy; 3CIRFF, University of Florence, Florence, Italy; 4Outcome Research Unit. Policlinics Umberto I, Rome, Italy Objective: To evaluate adherence to antihypertensive therapy (AHT) and the association between adherence to AHT, all-cause mortality, and cardiovascular (CV) morbidity in a large cohort of patients newly treated with antihypertensives in a clinical practice setting. Methods: An administrative database kept by the Local Health Unit of Florence (Italy) listing patient baseline characteristics, drug prescription, and hospital admission information was used to perform a population-based retrospective study including patients newly treated with antihypertensives, ≥18 years of age, with a first prescription between January 1, 2004 and December 31, 2006. Patients using antihypertensives for secondary prevention of CV disease, occasional spot users, and patients with early CV events, were excluded from the study cohort. Adherence to AHT was calculated and classified as poor, moderate, good, and excellent. A Cox regression model was conducted to determine the association among adherence to AHT and risk of all-cause mortality, stroke, or acute myocardial infarction. Results: A total of 31,306 patients, 15,031 men (48.0%), and 16,275 women (52.0%), with a mean age of 60.2 ± 14.5 years was included in the study. Adherence to AHT was poor in 8038 patients (25.7% of included patients), moderate in 4640 (14.8%), good in 5651 (18.1%), and excellent in 12,977 (41.5%). Compared with patients with poor adherence (hazard ratio [HR] = 1), the risk of all-cause death, stroke, or acute myocardial infarction was significantly lower in patients with good (HR = 0.69, P < 0.001) and excellent adherence (HR = 0.53, P< 0.001). Conclusions: These findings indicate that suboptimal adherence to AHT occurs in a substantial proportion of patients and is associated with poor health outcomes already in primary prevention of CV diseases. For health authorities, this preliminary evidence underlines the need for monitoring and improving medication adherence in clinical practice.
A new measure of patient satisfaction with ocular hypotensive medications: The Treatment Satisfaction Survey for Intraocular Pressure (TSS-IOP)
Mark J Atkinson, William C Stewart, Joel M Fain, Jeanette A Stewart, Ravinder Dhawan, Essy Mozaffari, Jan Lohs
Health and Quality of Life Outcomes , 2003, DOI: 10.1186/1477-7525-1-67
Abstract: Item content was developed by 4 heterogeneous patient focus groups (n = 32). Instrument validation involved 250 patients on ocular hypotensive medications recruited from ophthalmology practices in the Southern USA. Participants responded to demographic and test questions during a clinic visit. Standard psychometric analyses were performed on the resulting data.Of the 412 patients screened, 253 consented to participate, and 250 provided complete datasets. The sample included 44% male (n = 109), 44% Black (n = 109) and 57% brown eyed (n = 142) participants, with a mean age of 64.6 years (SD 13.1) and a history of elevated IOP for an average of 8.4 yrs (SD 7.8). A majority was receiving monotherapy (60%, n = 151).A PC Factor analysis (w/ varimax rotation) of the 31 items yielded 5 factors (Eigenvalues > 1.0) explaining 70% of the total variance. Weaker and conceptually redundant items were removed and the remaining 15 items reanalyzed. The satisfaction factors were; Eye Irritation (EI; 4 items), Convenience of Use (CofU; 3 items), Ease of Use (EofU; 3 items), Hyperemia (HYP; 3 items), and Medication Effectiveness (EFF; 2 items). Chronbach's Alphas ranged from .80 to .86. Greater distributional skew was found for less common experiences (i.e., HYP & EI with 65% & 48.4% ceilings) than for more common experiences (i.e., EofU, CofU, EFF with 10.8%, 20.8% & 15.9% ceilings). TSS-IOP scales converged with conceptually related scales on a previously validated measure of treatment satisfaction, the TSQM (r = .36 to .77). Evidence of concurrent criterion-related validity was found. Patients' symptomatic ratings of eye irritation, hyperemia and difficulties using the medication correlated with satisfaction on these dimensions (r = .30-.56, all p < .001). Clinicians' ratings of IOP control, severity of side effects and problematic medication use correlated with patients' satisfaction scores on these dimensions (r = .13-.26, all p < .01).This study provides initial evidence that th
Page 1 /100
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.