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无线颅内压监护仪  [PDF]
北京理工大学学报 , 2000,
Abstract: 研制无线颅内压监护仪。采用硅压力传感器为敏感元件,用双桥法实现温度补偿,通过电压/频率变换将压力信号转换为音频频率信号并利用无线调频发射/接收进行传输,由单片机控制进行定时采样、数字滤波、标度变换、报警判断、显示、打印以及串行数据发送等处理。该仪器克服了现有光纤颅内压监护仪的缺点,操作方便,探头寿命长。
高压氧对麻醉兔颅内压的影响
崔人镜
科学通报 , 1984,
Abstract: 高分压氧和高压氧对机体的作用和影响问题在实际潜水作业中和临床高压氧治疗中都经常涉及,因而对此问题的研究具有重要实际意义。颅腔是一个容积相对固定的腔隙,颅内脑组织、脑脊液和血液三者的相对恒定,维持正常颅内压力。颅内血液是唯一能很快起变化的成份,脑血流的变化直接影响颅内压力,同样,颅内压力的变化也可影响脑血流。已有实验证明,脑血流变化与颅内压力变化呈正相关。
高压氧对麻醉兔颅内压的影响  [PDF]
崔人镜
科学通报 , 1984,
Abstract: 高分压氧和高压氧对机体的作用和影响问题在实际潜水作业中和临床高压氧治疗中都经常涉及,因而对此问题的研究具有重要实际意义。颅腔是一个容积相对固定的腔隙,颅内脑组织、脑脊液和血液三者的相对恒定,维持正常颅内压力。颅内血液是唯一能很快起变化的成份,脑血流的变化直接影响颅内压力,同样,颅内压力的变化也可影响脑血流。已有实验证明,脑血流变化与颅内压力变化呈正相关。
颅内巨大动脉瘤的手术治疗  [PDF]
黄理金,冯文峰,漆松涛
南方医科大学学报 , 2012,
Abstract: 目的探讨颅内巨大动脉瘤的手术时机、手术方法及疗效。方法回顾性分析2001年1月~2010年1月南方医院神经外科治疗的15例颅内巨大动脉瘤。动脉瘤夹夹闭8例;动脉瘤孤立并颅内-颅外血管架桥术1例;大隐静脉移植颅内-颅外血管架桥并载瘤动脉闭塞3例;瘤体切除,瘤壁缝合1例;单纯孤立2例。结果死亡2例(13%)。其余13例经半年的随访,好12例(80%),差1例(7%)。结论巨大动脉瘤手术设计应个体化,术者应是具备血管重建能力的有经验的显微神经外科医师。
颅内静脉窦血栓治疗进展  [PDF]
李晓腾,张晓敏,董艳,侯立军
- , 2018, DOI: 10.16781/j.0258-879x.2018.02.0188
Abstract: 颅内静脉窦血栓是一种病因复杂、临床表现多样、相对少见的脑血管疾病。以往较难做出临床诊断,也缺乏有效的治疗方法。磁共振成像和脑血管造影等神经影像学检查技术的不断进步,为该病的诊断提供了重要帮助。在治疗方面,绝大多数患者经抗凝治疗获得了满意的结果,病情较重的患者可能需要接受血管内局部溶栓和机械碎栓、取栓等治疗。本文就颅内静脉窦血栓的几种治疗方法进行综述。
Cerebral venous sinus thrombosis (CVST) is a relatively rare disease with complex etiology and varied clinical characteristics. It is often difficult to make an accurate diagnosis of CVST and there is no effective treatment method. Neuroimaging techniques, including magnetic resonance imaging and cerebral angiography, have been continuously progressing and contribute to the diagnosis of CVST. Most patients respond well to systemic anticoagulation. The patients who are in a serious condition may require endovascular therapy such as local intravenous thrombolysis, mechanical thrombectomy and mechanical fragmentation. This article reviewed the therapeutic management progress of CVST
三维颅内血肿动态成像  [PDF]
徐管鑫,何为
重庆大学学报 , 2004,
Abstract: 基于电流场"异物扰动"成像方法,在三维球模型上对颅内血肿动态成像进行了仿真研究.研究了颅内血肿体积大小的改变对头颅表面电位改变的规律,还研究了导电性能差的颅骨的存在对头颅表面电位改变规律的影响.研究结果表明:从头颅表面两个不同的位置注入电流后,从头颅表面电位的变化规律可以反映出颅内血肿体积大小的改变情况,而且电流可以穿透颅骨.这将有助于医务人员根据头颅表面边界电位的变化情况来推测颅内血肿的变化情况.
颅内神经内分泌癌1例报告  [PDF]
彭林,程江鹏,黄理金,黄传平
南方医科大学学报 , 2005,
Abstract: 神经内分泌癌是由神经内分泌肿瘤恶变而来,多见于肺和腹腔器官,作者近期治疗1例极其罕见的颅内神经内分泌癌,报告如下。
经颅多普勒超声在颅内压增高监测中的临床价值  [PDF]
刘南平,陈景云,林树敏,马永盛
宁夏医科大学学报 , 2007,
Abstract: 目的探讨颅内压增高时床旁经颅多普勒超声(TCD)监测的应用价值。方法采用EMECOMPANIONⅢ型经颅多普勒超声诊断仪,对32例ICU重症监护患者均于床旁行TCD脑血流动力学检测。结果32例患者首次TCD检测26例(81.3%)分别为尖锐波、振荡波、钉子波、无血流信号及高流速改变;10例动态观察TCD改变,除2例高流速改变转归为正常外,余8例最终为无血流信号。结论TCD特征性的频谱改变与颅内压增高关系密切,可为临床提供早期脑死亡的判定依据,对重症患者的预后评价具有较高临床实用价值。
呼气末正压通气对犬脑内血肿高颅压的影响  [PDF]
闫润民,卢亦成,于明琨,楼美清,张光霁,朱诚
第三军医大学学报 , 2007,
Abstract: 目的观察不同水平呼气末正压通气(positiveend-expiratorypressure,PEEP)对犬额叶脑内血肿颅内高压的影响。方法18只犬随机分为正常颅压组(Ⅰ组,颅内压<18mmHg)、颅压中度增高组(Ⅱ组,颅内压25~40mmHg)和颅压高度增高组(Ⅲ组,颅内压>40mmHg)3组(每组各6只),全麻,气管切开插管,应用肌松剂,机械通气,右额叶脑内注入自体血制成颅内高压模型,PEEP从0开始每次增加3cmH2O,直到18cmH2O,每个水平持续20min,在对侧用光纤颅内压探头监测脑内颅内压(ICP)的变化,记录平均动脉压(MAP)和中心静脉压(CVP)并计算出脑灌注压(CPP)。?结果随着PEEP的递增,Ⅰ组颅内压上升,脑灌注压下降;Ⅱ、Ⅲ组颅内压略有下降,但Ⅱ组MAP、CPP上升,而Ⅲ组MAP下降,CPP下降;3组CVP都随PEEP增加而升高,但Ⅲ组上升幅度明显大于另两组(P<0.01)。结论应用PEEP通气时由于中心静脉压升高、脑静脉回流受阻和血流动力学改变,进而影响ICP和CPP。在正常颅内压状态下,PEEP使颅内压上升,在已有颅内高压存在时,PEEP对颅内压影响不明显,但在重度高颅压情况下,PEEP使CPP明显下降,提示在重度颅内高压需要应用PEEP通气时必须维持MAP,以保证足够的CPP。
颅内动脉狭窄伴未破裂颅内动脉瘤的临床特点及危险因素分析  [PDF]
赵海燕,韩金涛,樊东升
- , 2017,
Abstract: 目的 分析未破裂颅内动脉瘤在颅内动脉狭窄患者的发生率、临床特点,并探讨发生未破裂颅内动脉瘤的危险因素。 方法 收集自2012年1月至2015年12月在北京大学第三医院住院,数字减影血管成像(digital subtraction angiography,DSA)检查证实颅内动脉存在≥50%狭窄,并同时存在未破裂颅内动脉瘤患者的资料,并对患者临床、DSA影像资料进行回顾分析。结果 在273例≥50%颅内动脉狭窄的患者中,有17例(6.23%)存在未破裂颅内动脉瘤,患者年龄45~78岁,其中8例女性,9例男性。男性颅内动脉狭窄患者动脉瘤发病率为4.17%(9/216),女性颅内动脉狭窄患者动脉瘤发病率为14.4%(8/57),男、女性动脉瘤发病率差异有统计学意义( P<0.05)。16例(94.12%)动脉瘤位于颈内动脉系统,仅1例(5.88%)动脉瘤位于基底动脉尖;11例(64.71%)动脉瘤位于狭窄血管的远端,2例(11.76%)位于狭窄血管的近端,另有4例(23.53%)动脉瘤与狭窄不在同一血管;Logistic多因素分析显示,性别是颅内动脉狭窄患者发生未破裂颅内动脉瘤的独立危险因素。结论 颅内动脉狭窄患者发生动脉瘤的可能性远高于普通人群,女性较男性颅内动脉狭窄患者更易发生未破裂颅内动脉瘤。
【Abstract】 Objective To analyze the incidence of intracranial unruptured aneurysms in patients with intracranial artery stenosis, clinical features, and investigate the risk factors for unruptured intracranial aneurysms. Methods Medical records from all patients performed with digital subtraction angiography (DSA) who had been treated at Peking University Third Hospital, China, from January 2012 to December 2015 were retrospectively reviewed to identify cases coexistence with cerebral artery stenosis and unruptured intracranial aneurysm. Results Of 273 patients with cerebral artery stenosis (≥50%), intracranial unruptured aneurysms was observed in 17 cases (6.23%) from age of 45 to 78, among them 8 (47.06%) were female and 9 (52.94%) were male. The incidence of unruptured intracranial aneurysm in male patients was 4.17% (9/216), and that of female was 14.4% (8/57). There was statistically significant difference between the male and female incidence of intracranial aneurysm ( P<0.05). Of these 17 patients, 16 (94.12%) aneurysms were located in the internal carotid artery (ICA) system, 1 (5.88%) aneurysm was located at the tip of the basilar artery. In 11 cases (64.71%), aneurysms were located at the distal of the stenotic vessels, 2 (11.76%) were located at the proximal of the stenotic vessels, and 4 cases (23.53%) of which the aneurysm and stenosis were not in the same artery. Logistic multivariate analysis showed that gender was an independent risk factor for aneurysms in patients with cerebral arterial stenosis. Conclusion In the intracranial artery stenosis atients, the possibility of the occurrence of the aneurysm is much higher than the general population, and women were more prominent than man. Sex is an independent risk factor for aneurysms in patients with cerebral arterial stenosis.
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