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Comparing Artemisia sieberi Besser and Artemisia scoparia Waldst and Kit. Elemental Content Grown on Crusted and Uncrusted Soils  [PDF]
A. Tavili,M. Jafari
Pakistan Journal of Nutrition , 2006,
Abstract: Biological soil crusts occur as assemblage of lichens, mosses, liverworts, and cyanobacteria. Lichens and mosses are the two important components of biological soil crusts, especially in arid and semiarid rangeland environments, where vascular plants vegetation is poor. Biological soil crusts contribute to a variety of ecological functions. The current study was carried out to compare two native shrubs elemental content. For this purpose, aerial parts of two native annual and perennial shrubs, Artemisia scoparia and A. sieberi, were collected from crusted and uncrusted soils in Qara Qir rangelands, next to Iran - Turkmenistan border line. N, P, K, Zn and Fe of the samples were measured. Factorial experiment based on Completely Randomized Design (CRD) was used for data analysis. Results showed that N, Fe and Zn content of samples collected from crusted and uncrusted sites were significantly different. Different treatments showed different behavior for each of mentioned elements. A. scoparia related to crusted and uncrusted soils contained the highest and lowest nitrogen percent, respectively. Zinc of A. sieberi and A. scoparia both collected from crusted site showed the greatest and lowest amount, respectively. This status was true for Fe changes in understudy treatments, too.
Artemisia scoparia – A new source of artemisinin  [cached]
Aditi Singh,Renu Sarin
Bangladesh Journal of Pharmacology , 2010,
Abstract: Artemisinin is considered as the most active and potent antimalarial drug. Till date Artemisia annua Linn. plant is the only source for its production The present investigation was carried out with an objective to search a new plant for artemisinin. An attempt was made on a perennial faintly odoratus herb, Artemisia scoparia Waldst et Kit. to find out an alternative of A. annua for the production of artemisinin. The yield of artemisinin was higher in aerial plant parts (0.015%) in comparison to callus culture (0.001%). The present study concluded that Artemisia scoparia contains an antimalarial drug artemisinin.
Scientific Annals of Alexandru Ioan Cuza University of Iasi. New Series, Section 2. Vegetal Biology , 2011,
Abstract: The species subjected to the study belong to Asteraceae family, Artemisia genus found in Romania’s spontaneous flora. This work presents an anatomic study of petiole from Artemisia santonica and Artemisia scoparia plants. The petiole secretory structures are represented by hairs and ducts.
Evaluation of antimalarial, free-radical-scavenging and insecticidal activities of Artemisia scoparia and A. Spicigera, Asteraceae
Afshar, Fariba H.;Delazar, Abbas;Janneh, Omar;Nazemiyeh, Hossein;Pasdaran, Ardalan;Nahar, Lutfun;Sarker, Satyajit D.;
Revista Brasileira de Farmacognosia , 2011, DOI: 10.1590/S0102-695X2011005000144
Abstract: artemisia species (asteraceae), widespread throughout the world, are a group of important medicinal plants. the extracts of two medicinal plants of this genus, artemisia scoparia waldst. & kit. and a. spicigera c. koch, were evaluated for potential antimalarial, free-radical-scavenging and insecticidal properties, using the heme biocrystallisation and inhibition assay, the dpph assay and the contact toxicity bioassay using the pest tribolium castaneum, respectively. the methanol extracts of both species showed strong free-radical-scavenging activity and the rc50 values were 0.0317 and 0.0458 mg/ml, respectively, for a. scoparia and a. spicigera. the dichloromethane extracts of both species displayed a moderate level of potential antimalarial activity providing ic50 at 0.778 and 0.999 mg/ml for a. scoparia and a. spicigera, respectively. both species of artemisia showed insecticidal properties. however, a. spicigera was more effective than a. scoparia.
Evaluation of antimalarial, free-radical-scavenging and insecticidal activities of Artemisia scoparia and A. Spicigera, Asteraceae  [cached]
Fariba H. Afshar,Abbas Delazar,Omar Janneh,Hossein Nazemiyeh
Revista Brasileira de Farmacognosia , 2011,
Abstract: Artemisia species (Asteraceae), widespread throughout the world, are a group of important medicinal plants. The extracts of two medicinal plants of this genus, Artemisia scoparia Waldst. & Kit. and A. spicigera C. Koch, were evaluated for potential antimalarial, free-radical-scavenging and insecticidal properties, using the heme biocrystallisation and inhibition assay, the DPPH assay and the contact toxicity bioassay using the pest Tribolium castaneum, respectively. The methanol extracts of both species showed strong free-radical-scavenging activity and the RC50 values were 0.0317 and 0.0458 mg/mL, respectively, for A. scoparia and A. spicigera. The dichloromethane extracts of both species displayed a moderate level of potential antimalarial activity providing IC50 at 0.778 and 0.999 mg/mL for A. scoparia and A. spicigera, respectively. Both species of Artemisia showed insecticidal properties. However, A. spicigera was more effective than A. scoparia.
Callogenesis and Direct Organogenesis of Artemisia scoparia  [PDF]
Nasir Aslam,Muhammad Zia,M. Fayyaz Chaudhary
Pakistan Journal of Biological Sciences , 2006,
Abstract: The present study was initiated to develop a protocol for the effective propagation of Artemisia scoparia. Shoot tip, leaf and petiole explants were used for callus production and shoot tips were used for direct organogenesis. Murashige and skoog medium supplemented with different concentrations and combinations were used through entire study. MS medium supplemented with 2,4-D and NAA in combination at different concentrations proved best for callus induction from all types of explants. Multiple shoots from shoot tip explants were produced at NAA in combination with BA or Kin. Best root initiation was observed at NAA supplemented in MS medium.
Urease Inhibitory Activity of Aerial Parts of Artemisia scoparia: Exploration in an In Vitro Study  [PDF]
Murad Ali Khan,Haroon Khan,Shafiq Ahmad Tariq,Samreen Pervez
Ulcers , 2014, DOI: 10.1155/2014/184736
Abstract: Artimisia scoparia has been used in the treatment of different disorders including ulcers. The current study was therefore designed to investigate the aerial parts of??Artemisia scoparia (crude extract, total sterol and flavonoidal contents, and aqueous fraction) for its urease inhibitory potential. The crude of the plant evoked marked attenuation on urease activity, when tested in various concentrations with IC50 values of 4.06?mg/ml. The inhibitory potential was further augmented in the aqueous fraction (IC50: 2.30?mg/ml) of the plant. When the total sterol and flavonoidal contents were challenged against urease, both showed concentration dependent activity; the latter showed maximum potency with IC50 values of 8.04 and 2.10?mg/ml, respectively. In short, the aerial parts of the plant demonstrated marked antagonism on urease and thus our study validated the traditional use of Artemisia scoparia in the treatment of ulcer. 1. Introduction Urease (urea amidohydrolase) is usually found in different bacteria, fungi, algae, and plants, an enzyme that catalyzes the hydrolysis of urea to ammonia and carbamate, which is the final step of nitrogen metabolism in living organisms [1]. Carbamate rapidly and spontaneously decomposes, yielding a second molecule of ammonia. These reactions may cause significant increase in pH and are responsible for negative effects of urease activity in human health and agriculture [2, 3]. From the medical viewpoint, infections produced by these bacteria such as Helicobacter pylori and Proteus mirabilis usually have a high urease activity. Urease is central to H. pylori metabolism and virulence, is necessary for its colonization of the gastric mucosa, and is a potent immunogen that elicits a vigorous immune response. This enzyme is used for taxonomic identification and for diagnosis and followup after treatment and is a vaccine candidate. Urease represents an interesting model for metalloenzyme studies. Before the discovery of H. pylori, humans were thought to produce “gastric urease.” It is now known that the source of this notable protein is this bacterium, which colonizes the gastric mucosa of humans. It contributes in urinary tract and gastrointestinal infections, probably augmenting the severity of several pathological conditions like peptic ulcers and stomach cancer as in the case of H. pylori. Ureases are also involved in the development of different human and animal pathogenicity of urolithiasis, pyelonephritis, hepatic encephalopathy, hepatic coma, and urinary catheter encrustation [4–6]. Being involved in the
Artemisia scoparia Enhances Adipocyte Development and Endocrine Function In Vitro and Enhances Insulin Action In Vivo  [PDF]
Allison J. Richard, Scott Fuller, Veaceslav Fedorcenco, Robbie Beyl, Thomas P. Burris, Randall Mynatt, David M. Ribnicky, Jacqueline M. Stephens
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0098897
Abstract: Background Failure of adipocytes to expand during periods of energy excess can result in undesirable metabolic consequences such as ectopic fat accumulation and insulin resistance. Blinded screening studies have indicated that Artemisia scoparia (SCO) extracts can enhance adipocyte differentiation and lipid accumulation in cultured adipocytes. The present study tested the hypothesis that SCO treatment modulates fat cell development and function in vitro and insulin sensitivity in adipose tissue in vivo. Methods In vitro experiments utilized a Gal4-PPARγ ligand binding domain (LBD) fusion protein-luciferase reporter assay to examine PPARγ activation. To investigate the ability of SCO to modulate adipogenesis and mature fat cell function in 3T3-L1 cells, neutral lipid accumulation, gene expression, and protein secretion were measured by Oil Red O staining, qRT-PCR, and immunoblotting, respectively. For the in vivo experiments, diet-induced obese (DIO) C57BL/6J mice were fed a high-fat diet (HFD) or HFD containing 1% w/w SCO for four weeks. Body weight and composition, food intake, and fasting glucose and insulin levels were measured. Phospho-activation and expression of insulin-sensitizing proteins in epididymal adipose tissue (eWAT) were measured by immunoblotting. Results Ethanolic extracts of A. scoparia significantly activated the PPARγ LBD and enhanced lipid accumulation in differentiating 3T3-L1 cells. SCO increased the transcription of several PPARγ target genes in differentiating 3T3-L1 cells and rescued the negative effects of tumor necrosis factor α on production and secretion of adiponectin and monocyte chemoattractant protein-1 in fully differentiated fat cells. DIO mice treated with SCO had elevated adiponectin levels and increased phosphorylation of AMPKα in eWAT when compared to control mice. In SCO-treated mice, these changes were also associated with decreased fasting insulin and glucose levels. Conclusion SCO has metabolically beneficial effects on adipocytes in vitro and adipose tissue in vivo, highlighting its potential as a metabolically favorable botanical supplement.
Chemical components of Artemisia scoparia volatile oil and its poison activity to mosquito

ZHOU Tian,GUO Jixun,HAN Defu,XING Fu,TIAN Shangyi,

应用生态学报 , 2006,
Abstract: The study showed that Artemisia scoparia contained 0.38% of volatile oil, in which, a total of 38 chemical components were identified, accounting for 87.53% of the substances detected,and 12 kinds of terpenoids compounds were the main components, accounting for 45.04% of the total. The oil had a high and rapid poison activity on Culex pipiens pallens larva and adult. The LC50 value for the larva was 12.5 mg x L(-1) within 2 days, and the mortality of the adult in 24 hours was 70% and 100% when the dosage was 1 and 10 microg x cm(-2).

DU Feng,LIANG Zong-Suo,SHAN Lun,CHEN Xiao-Yan,

植物生态学报 , 2006,
Abstract: Background and Aims In hilly Loess region, Artemisia scoparia is always the dominator in the early abandoned field communities. It may be replaced by Agropyron cristatum or Heteropappus altaicus or Stipa bungeana in next succession stage when no disturbance occurs. In order to study the direction of Artemisia scoparia community succession under different standing conditions, we conducted transplant experiments to test the intraspecfic and interspecfic competition of Artemisia scoparia in river terrace and northern mound land and, at the same time, its morphological traits were investigated. Methods In the experiments, nine species (three coexisting species, five later sere species and Artemisia scoparia itself) were chosen and transplanted as test species, but due to the low survival of two species, only seven species were analyzed to test the relative competition ability to phytometer Artemisia scoparia under different standing conditions. Key Results The results show that the individuals tend to be miniaturized, i.e., its communities are composed mainly of small-sized individuals and competition can change the morphological traits. The unit biomass competition intensity is better than total competition intensity in explaining plants' relative competitive ability when local conditions and plant size are considered. Under the northern mound land and the lowest river terrace, late-successional and perennials species have higher competitative ability than early-successional and annual plants, suggesting that the competition of late- against early-successional species is one of the driving force to succession. Comparison of the competition between the seven test species and the unit biomass of Artemisia scoparia, the northern mound land ranks the first, lower river terrace the second and the lowest terrace the third, suggesting that intensive competition occurs more severely in poor growing conditions. There is significant difference in the ability of competition between the test species and Artemisia scoparia from the lowest river terrace to the northern mound land, suggesting that the ranks of the competition ability may vary depending on standing conditions. Conclusions As competition is one of the decisive factors in constructing plant community, the shift or variation of competition ability between coexisting species and sere species may result in different community structure and dynamics, so it changes the direction and pathway of succession under different standing conditions.
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