oalib
Search Results: 1 - 10 of 100 matches for " "
All listed articles are free for downloading (OA Articles)
Page 1 /100
Display every page Item
《文选》陆善经注引书研究  [PDF]
尹曙光?
天府新论 , 2012,
Abstract: 本文分析了保存在《文选集注》中的陆善经注所征引92种书籍的情况.其中大部分所引内容与现存版本相差无几,也有个别内容大相径庭,还有一些则仅保留在陆注中.对于陆善经习引一些书籍的原因,也作了初步探赜.
从颜师古注和李善注的比较看唐代典籍注释特点
 [PDF]

黄方方
- , 2016,
Abstract: 摘要 在唐代注释学中,颜师古和李善堪称代表性人物,各自代表了“汉书学”和“文选学”注释发 展的最高水平。《汉书》与《文选》由于年代相去未远,故其中所收录的作品有重合之处。通过对颜师古注和 李善注的比较,发现唐代典籍的注释特点主要有:内容方面以训诂词义、疏通文意为主,属语文学注释;原则 方面以求实为宗旨,注而有征,实事求是,重考辨征引;方法方面充分吸取和利用前人的研究成果,并从理论 上进行总结和扩展。
注蒸汽条件下供氢催化改质稠油及其沥青质热分解性质  [PDF]
赵法军,刘永建,赵国,胡绍彬
化工进展 , 2010,
Abstract: 利用CWYF-Ⅰ型高压反应釜模拟热采条件下,以甲酸作为供氢体、以自制的油溶性有机镍盐为催化剂进行的稠油水热裂解反应。考察了供氢体的加入对催化水热裂解反应前后稠油黏度、族组成及硫含量的影响,并采用TG-DTA分析法对供氢催化改质反应前后稠油中沥青质的热转化行为进行了分析。结果表明,随着加入供氢体质量分数增加,供氢催化水热裂解后稠油降黏率增大,饱和烃、芳香烃含量增加,胶质、沥青质含量降低,同时硫含量下降。供氢催化水热裂解反应后的稠油中沥青质TG-DTA曲线分析表明,供氢催化水热裂解反应后稠油中沥青质失重量高于催化水热裂解反应前稠油中含有的沥青质的失重量。经过供氢催化水热裂解反应,稠油中沥青质的稳定性下降。
Kupffer cells and alcoholic liver disease
Cubero,F. J.; Nieto,N.;
Revista Espa?ola de Enfermedades Digestivas , 2006, DOI: 10.4321/S1130-01082006000600007
Abstract: liver disease is a major cause of illness and death worldwide. a central component in the complex network leading to the development of alcoholic liver disease is the activation of kupffer cells by endotoxin and other soluble mediators. alcohol consumption induces a state of ‘leaky gut' increasing plasma and liver endotoxin levels. when kupffer cells become activated, they interact with a complex of proteins located on the extracellular membrane signaling to produce a wide array of soluble factors, including cytokines, chemokines, growth factors, cyclooxygenase and lipoxygenase metabolites, and reactive oxygen species such as superoxide anion, hydrogen peroxide, and nitric oxide, all of which provide physiologically diverse and pivotal paracrine effects on all other liver cell types and, ultimately, liver injury. kupffer cells are also central to the liver homeostatic response to injury as upon cellular degenerative changes, they immediately respond to the insult and release mediators to orchestrate inflammatory and reparative responses. thus, the homeostatic responses are initiated by kupffer cell-derived mediators at the cellular level and underlie the liver's defense and reparative mechanisms against injury. in order to understand better the role of kupffer cells in the onset of liver injury, animal models in which kupffer cells are inactivated, and cell culture settings (e.g. co-cultures) are being used with promising results that advance our understanding of alcoholic liver disease.
?横轴改?  [PDF]
程滋民
地质与勘探 , 1957,
Abstract: 103?利用500m?机?横?改?成300m??用横?,解决了备件缺乏??。其方法是将500m?横轴的键槽用雷焊填补,再车成300m转机横轴的设计尺寸,即可使用.
Kupffer cells and alcoholic liver disease Células de Kupffer y hepatopatía alcohólica  [cached]
F. J. Cubero,N. Nieto
Revista Espa?ola de Enfermedades Digestivas , 2006,
Abstract: Liver disease is a major cause of illness and death worldwide. A central component in the complex network leading to the development of alcoholic liver disease is the activation of Kupffer cells by endotoxin and other soluble mediators. Alcohol consumption induces a state of ‘leaky gut' increasing plasma and liver endotoxin levels. When Kupffer cells become activated, they interact with a complex of proteins located on the extracellular membrane signaling to produce a wide array of soluble factors, including cytokines, chemokines, growth factors, cyclooxygenase and lipoxygenase metabolites, and reactive oxygen species such as superoxide anion, hydrogen peroxide, and nitric oxide, all of which provide physiologically diverse and pivotal paracrine effects on all other liver cell types and, ultimately, liver injury. Kupffer cells are also central to the liver homeostatic response to injury as upon cellular degenerative changes, they immediately respond to the insult and release mediators to orchestrate inflammatory and reparative responses. Thus, the homeostatic responses are initiated by Kupffer cell-derived mediators at the cellular level and underlie the liver's defense and reparative mechanisms against injury. In order to understand better the role of Kupffer cells in the onset of liver injury, animal models in which Kupffer cells are inactivated, and cell culture settings (e.g. co-cultures) are being used with promising results that advance our understanding of alcoholic liver disease.
Characterization of Kupffer cells in livers of developing mice
Bryan G Lopez, Monica S Tsai, Janie L Baratta, Kenneth J Longmuir, Richard T Robertson
Comparative Hepatology , 2011, DOI: 10.1186/1476-5926-10-2
Abstract: Sections of liver tissue from early postnatal mice were prepared using immunocytochemical techniques. The Kupffer cells were identified by their immunoreactivity to the F4/80 antibody, whereas endothelial cells were labelled with the CD-34 antibody. In addition, Kupffer cells and endothelial cells were labelled by systemically injected fluorescently labelled latex microspheres. Tissue slices were examined by fluorescence microscopy.Intravenous or intraperitonal injections of microspheres yielded similar patterns of liver cell labelling. The F4/80 positive Kupffer cells were labelled with both large (0.2 μm) and small (0.02 μm) diameter microspheres, while endothelial cells were labelled only with the smaller diameter microspheres. Microsphere labelling of Kupffer cells appeared stable for at least 6 weeks. Cells immunoreactive for F4/80 were identified as early as postnatal day 0, and these cells also displayed uptake of microspheres. Numbers of F4/80 Kupffer cells, relative to numbers of albumin positive hepatocytes, did not show a significant trend over the first 2 postnatal weeks.Kupffer cells of the developing mouse liver appear quite similar to those of other mammalian species, confirming that the mouse presents a useful animal model for studies of liver macrophage developmental structure and function.The important roles performed by the liver in the storage and release of nutrients and in the neutralization and elimination of a variety of toxic substances have prompted investigations of its cellular constituents and organization. Some of these studies have been carried out in human liver, but the importance of having an experimental model system has prompted several investigations of liver organization in laboratory mammals, primarily rats [1-7]. In species studied thus far, investigations have demonstrated that the liver is comprised of parenchymal cells, the hepatocytes [8-10], and a variety of non-parenchymal resident cells including a population of macroph
基本的环境善物与罗尔斯的“基本善”  [PDF]
王韬洋
华东师范大学学报(哲学社会科学版) , 2012,
Abstract: 基本的环境善物是否能够以及如何能够被纳入社会基本善的清单,从而成为罗尔斯正义理论的分配对象?对于这一问题的讨论可以沿两种思路展开。第一种思路是以发掘基本善概念中罗尔斯本人忽视的环境维度为出发点,尝试以直接扩展基本善的清单的方式将基本的环境善物纳入罗尔斯的分配正义理论;第二种思路则是以罗尔斯后期思想中对“医疗保健中的正义问题”的讨论为媒介,通过显示基本环境善物在保持公民“最低必要能力”方面的重要性,来论证将基本的环境善物纳入社会基本善清单的合理性。
Effects of glycine on phagocytosis and secretion by Kupffer cells in vitro  [cached]
Hui-Wen Wu,Ke-Ming Yun,De-Wu Han,Rui-Ling Xu
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i20.2576
Abstract: AIM: To investigate the effects and mechanisms of action of glycine on phagocytosis and tumor necrosis factor (TNF)-α secretion by Kupffer cells in vitro. METHODS: Kupffer cells were isolated from normal rats by collagenase digestion and Percoll density gradient differential centrifugation. After culture for 24 h, Kupffer cells were incubated in fresh Dulbecco's Modification of Eagle’s Medium containing glycine (G1: 1 mmol/L, G2: 10 mmol/L, G3: 100 mmol/L and G4: 300 mmol/L) for 3 h, then used to measure phagocytosis by a bead test, TNF-α secretion after lipopolysaccharide stimulation by radioactive immunoassay, and microfilament and microtubule expression by staining with phalloidin-fluorescein isothiocyanate (FITC) or a monoclonal anti-α tubulin-FITC antibody, respectively, and evaluated under a ultraviolet fluorescence microscope. RESULTS: Glycine decreased the phagocytosis of Kupffer cells at both 30 min and 60 min (P < 0.01, P < 0.05). The numbers of beads phagocytosed by Kupffer cells in 30 min were 16.9 ± 4.0 (control), 9.6 ± 4.1 (G1), 12.1 ± 5.7 (G2), 8.1 ± 3.2 (G3) and 7.5 ± 2.0 (G4), and were 22.5 ± 7.9 (control), 20.1 ± 5.8 (G1), 19.3 ± 4.8 (G2), 13.5 ± 4.7 (G3) and 9.2 ± 3.1 (G4) after 60 min. TNF-α secretion by Kupffer cells in G1 (0.19 ± 0.03), G2 (0.16 ± 0.04), G3 (0.14 ± 0.03) and G4 (0.13 ± 0.05) was significantly less than that in controls (0.26 ± 0.03, P < 0.01), and the decrease in secretion was dose-dependent (P < 0.05). Microfilaments of Kupffer cells in G2, G3 and G4 groups were arranged in a disorderly manner. The fluorescence densities of microtubules in G1 (53.4 ± 10.5), G2 (54.1 ± 14.6), G3 (64.9 ± 12.1) and G4 (52.1 ± 14.2) were all lower than those in the controls (102.2 ± 23.7, P < 0.01), but the decrease in microtubule fluorescence density was not dose-dependant. CONCLUSION: Glycine can decrease the phagocytosis and secretion by Kupffer cells in vitro, which may be related to the changes in the expression of microfilaments and microtubules induced by Kupffer cells.
管钳子改??活  [PDF]
直爽
地质与勘探 , 1957,
Abstract: ?探??常用的工具――管?子,在工作中损坏是?多的,特?是?子?和?子箍更易?坏,而?子把损坏的?少。因此利用?子把再加工改??活成管?子是一?有效的节?措施。105勘探?已??用?一方法,解?了管?子改??活?题。他们的改??程是:???的???加?剁?,每????可?成????。剁?后,再加?至可??度(?1150°~200℃左右),?行?加工成?子?形?,再???工加工即成成品。其次再利用??粒??(如?之1)改??子箍,首先作成如?之2及3所示的???模,其中3?芯模,4??模。具?作法是???粒??按改?管?子箍所需的?度在?床上切好,放在?中加?,
Page 1 /100
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.