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Causes of uveitis in a tertiary center in Western Saudi Arabia
Shaik HM. Nizamuddin,Ahmed M. Bawazeer
Saudi Medical Journal , 2013,
Abstract: Objectives: To analyze the causes of uveitis and compare our results with national and international published studies. Methods: This is a retrospective review of medical records of patients who attend the uveitic clinic of Magrabi Eye & Ear Hospital in Jeddah, Kingdom of Saudi Arabia from January 1999 to December 2011. Results: We encountered 823 eyes of 587 uveitis patients (male: 319 [54%] and female: 268 [46%]). Native Saudi patients constituted 52% of our total population, expatriate Arabs 23%, and Afro-Asians 23%. Average age at presentation was 34.8±12.83 (range 5-70) years. Unilateral presentation was noted in 351 (60%) and bilateral in 236 (40%) patients. Idiopathic anterior uveitis was the most common diagnosis (n=268, 45.7%). Anterior uveitis was the most common anatomical diagnosis (n=335, 57.1%) followed by panuveitis (n=151, 25.7%), posterior uveitis (n=51, 8.7%) and intermediate uveitis (n=50, 8.5%). There were 50 patients (8.5%) of Behcet’s disease, 48 patients (8.2%) of Vogt-Koyanagi-Harada disease (VKH) and 35 cases (6%) of toxoplasmosis. Conclusion: The most common cause of anatomic diagnosis was anterior uveitis. Behcet’s disease was the most common identifiable cause of uveitis followed by VKH. The most common cause of infectious uveitis was toxoplasmosis. Idiopathic anterior uveitis was the most common uveitic entity.
Renal Abnormalities in Patients with Sickle Cell Disease: A Single Center Report from Saudi Arabia  [cached]
Aleem Aamer
Saudi Journal of Kidney Diseases and Transplantation , 2008,
Abstract: Patients with sickle cell disease (SCD) are at increased risk of serious morbidity and mortality. Renal abnormalities in SCD are well known but renal involvement in Saudi patients with SCD has not been studied. We sought to identify renal abnormalities in adolescent and adult Saudi patients with SCD. We prospectively studied 73 patients with SCD followed up at King Khalid University Hospital, Riyadh, Saudi Arabia from July 2005 to November 2006,. All patients underwent evaluation of kidney function and urine examination to detect proteinuria and other urinary abnormalities. In addition, 53 patients from the cohort had 24-hour urine collection to measure creatinine clearance and to quantitate proteinuria. The patient population consisted of 34 males (46.5%) and 39 females (53.5%) with a median age of 23 years (range 14-40). Proteinuria was present in 30 patients (41%). Creatinine clearance was low in 12 patients (22.5%) and seven of these patients had low or low-normal serum creatinine despite reduced creatinine clearance. Low serum creatinine was common and present in 28 patients (38%). Two patients had chronic renal failure and one of them is on regular dialysis. Other abnormalities detected include hematuria in seven patients (8.5%) and hemoglobinuria in 12 patients (14.5%). In conclusion, renal abnormalities are present in a significant number of Saudi patients with SCD and proteinuria is the most common abnormality. Serum creatinine may remain low or within low-normal range in SCD patients despite reduced creatinine clearance. As proteinuria is a risk factor for developing renal failure in future, routine screening of SCD patients is recommended for timely intervention in order to prevent or delay renal damage.
Pattern of childhood blindness at a referral center in Saudi Arabia.  [cached]
Tabbara Khalid,El-Sheikh Hisham,Shawaf Shucri
Annals of Saudi Medicine , 2005,
Abstract: BACKGROUND : An understanding of the causes of blindness and the magnitude of the problem is crucial in designing effective intervention and prevention programs. We undertook this retrospective review to determine the causes of childhood blindness at an eye referral center. PATIENTS AND METHODS : We reviewed charts of children who presented between August 1997 and August 2003. All children had a complete ophthalmologic examination. Blindness was defined as a visual acuity < 20/400, visual impairment as visual acuity between 20/400 and 20/60, and visual loss as a visual acuity < 20/60. RESULTS : A total of 5217 children included 220 (59%) males and 152 (41%) females (age range 2 to 18 years, mean age, 10 years). One hundred twelve (2%) were blind and 260 (5%) had visual impairment. The most common causes of bilateral blindness included optic nerve diseases, retinal disorders, and cataract. The most common causes of unilateral blindness included trauma, retinal diseases, refractive errors, and optic nerve diseases. The most common causes of bilateral visual impairment included refractive errors, corneal diseases, retinal disorders, cataract, and congenital nystagmus. Genetically determined disorders were observed in 37 (70%) of 53 patients with bilateral blindness, and in 52 (56%) of 93 patients with bilateral visual impairment. The incidence of consanguinity among parents of children with acquired causes was 2 (3%) of 59 patients compared to 34 (38%) of 89 among genetically determined causes ( P < 0.001). CONCLUSION : Genetically determined disorders continue to play an important role in the causation of childhood blindness among patients attending our referral center in Saudi Arabia. Genetic counseling, early eye screening of children and public education may help in the prevention of visual disorders in children.
Celiac disease in children and adolescents at a singe center in Saudi Arabia  [cached]
Saadah Omar
Annals of Saudi Medicine , 2011,
Abstract: Background and Objectives : Celiac disease (CD) is an immune-mediated enteropathy, induced by gluten in genetically susceptible individuals. The objective of this study was to describe the clinical pattern of CD in children from the western region of Saudi Arabia. Design and Setting : Retrospective, hospital-based. Patients and Methods : This study included children with a biopsy-proven diagnosis of CD made between September 2002 and July 2007. Children were admitted to the endoscopy unit for a small-bowel biopsy if they had gastrointestinal symptoms suggestive of CD or if they were positive for a CD-antibody screen performed for the high-risk groups. Results : Eighty children were identified with a diagnosis of CD. Their mean (SD) age was 9.6 (4.9) years (range, 0.5-18 years). There were 44 (55%) female patients. Forty-one (51%) patients were detected during screening of high-risk groups, while 39 (49%) patients had classical symptoms of malabsorption. The screening also detected asymptomatic patients. Of 65 patients tested, 11 (17%) had elevated liver function tests, which reverted to normal after introduction of a gluten-free diet (GFD) except in one case. Seventy-three (91%) patients were positive for anti-tissue transglutaminase antibodies, 18 (23%), for IgG anti-gliadin antibodies; and 46 (58%), for IgA anti-gliadin antibodies. Forty-one (56%) patients showed good adherence to GFD as assessed by dietary history and the decline in anti-tTG level. Conclusion : CD may present with classical symptoms or be identified through screening programs. Growth and laboratory abnormalities usually improve after introduction of a GFD. Adherence to a GFD remains a problem; therefore, thorough assessment and counseling at the time of diagnosis and ongoing care are crucial.
Proptosis as a manifestation of neuroblastoma
ST Hlongwane, M Pienaar, G Dekker, A Brandt, D van der Merwe, BH Louw, S Dajee
South African Journal of Radiology , 2006,
Abstract: Neuroblastoma occurs mainly in childhood and approximately 20% of cases have orbital metastases. Proptosis can be the only manifestation of metastatic neuroblastoma. Early investigation is important, as metastatic disease requires aggressive management. We present a case of a 7-yearold girl initially presenting with proptosis. South African Journal of Radiology Vol. 10 (4) 2006: pp. 31-32
Unconventional therapy use among asthma patients in a tertiary care center in Riyadh, Saudi Arabia  [cached]
Al Moamary Mohamed
Annals of Thoracic Medicine , 2008,
Abstract: Objectives: Unconventional therapy (UT) is a therapeutic practice of alternative and complementary medicine that is not currently considered an integral part of modern medical practice. The aim of this article is to investigate the experience of Saudi patients with UT modalities in the treatment of asthma. Materials and Methods: We carried out a cross-sectional study of asthma patients referred to King Abdulaziz Medical City, Riyadh, Saudi Arabia, during the year 2004. Information was collected using a pre-designed questionnaire administered through interviews. Results: Two hundred consecutive patients with a mean age of 52.3 years (±18.7) were included in this study. Sixty-nine (34.5%) of those patients used some form of UT in the previous year. There was a tendency to use UT among the older age group ( P = 0.029) and among those with longer duration of disease ( P = 0.009). However, there was no significant correlation observed between the use of UT and gender, FEV 1 , or disease control. The most commonly used form of UT was recitation of Holy Quran (9%), honey (24.5%), herbs (23.5%), cautery (12%), and blackseed (10%). There was no significant correlation between disease control and the use of modalities. Conclusion: Unconventional therapy is frequently practiced by asthma patients in Saudi Arabia, who commonly believe that UT will lead to improvement. The lack of evidence necessitates the fostering of a national project to address the practice of UT.
Trends of Summertime Ground-Level Peroxyacyl Nitrates Concentrations in Beijing, China from 2006 to 2014

- , 2016, DOI: 10.13209/j.0479-8023.2016.033
Abstract: 摘要 2006—2014年夏季, 使用PANs在线监测仪对北京大气中PANs浓度进行监测, 期间NOx浓度以每年1.7 nL/L (约4%/a)的速率下降, PAN浓度以每年0.03 nL/L (约3%/a)的速率下降, O3浓度却以每年1.5 nL/L(约4%/a)的速率上升, 表明这些年采取的NOx治理措施对控制PAN浓度有效, 治理O3需要在控制NOx的同时加强对VOCs排放的控制。
Abstract Ambient concentrations of PANs and other related air pollutants were monitored at an urban site in Beijing each August from 2006 to 2014. The NOx concentration decreased at a rate of 1.7 nL/(L/yr) (about 4%/yr), and the PAN concentration decreased at a rate of 0.03 nL/(L/yr) (about 3%/yr), while the O3 concentration increased at a rate of 1.5 nL/(L/yr) (about 4%/yr), indicating that the measures taken to cut NOx were effective for controlling PAN concentration. Beijing needs to strengthen the control of VOCs with reducing NOx emissions for reducing O3 concentration.
2006 - 2014年天津地区医院德国小蠊监测分析
Surveillance of Blattella gemanica in hospitals of Tianjin, 2006-2014

- , 2017,
Abstract: 目的 了解天津地区医院病媒生物监测点德国小蠊侵害和种群密度及季节消长,为医院的德国小蠊防治提供依据。方法 2006 - 2014年在天津地区医院病媒生物监测点用粘捕法对病房的德国小蠊进行监测,并对监测结果进行统计分析。结果 2006 - 2014年天津地区医院病媒生物监测点德国小蠊总体平均侵害率5.18 %,平均密度0.25只/张。在16个监测区县中,经济欠发达的郊县地区(老五县)和新兴工业区(环城四区)的医院德国小蠊侵害率和密度相对较高,市内六区和滨海新区较低。德国小蠊侵害率及密度的季节消长呈单峰型,高峰为5 - 8月的夏季。德国小蠊侵害率和密度有年度波动现象,侵害率2007 年最高,2013年最低;密度2008年最高,2013年最低。结论 初步掌握了天津地区医院德国小蠊的侵害特征、种群密度、区域差异、季节消长和年度变化规律,为医院德国小蠊监测、风险评估、预测预警及控制提供基础数据。
A Topic Diathesis In Hereditary Ichthyosis Patients Attending A Tertiary Health Care Center In Saudi Arabia
Al-Akloby Omar M Al-Amro
Indian Journal of Dermatology , 2004,
Abstract: The occurrence of atopic diathesis in hereditary ichthyosis (HI) has not been documented in Saudi patients. The atopic manifestations in histopathologically confirmed HI patients attending the dermatology clinic of king Fahad Hospital of the University at Al-Khobar city, Saudi Arabia is discussed in this study. From the dermatology OPD logbook, all Saudi patients with confirmed HI seen between January 1990 to December 1995 were included in the study. The findings regarding atopic manifestations were extracted into data collection forms and analyzed. During the 5 year study period, 10,455 new cases were seen in our dermatology OPD. Of these, 61 had hereditary icthyosis, with 37 males and 24 females with a male to female ratio of 1.5:1. Thus, the frequency of HI among Saudi hospital attendees was 6 per 1000 new cases. The type of HI was ichthyosis vulgaris in 25 (41%) patients, X-linked recessive ichthyosis in 11 (18%), lamellar ichthyosis in 4(7%), bullous ichthyosiform erythroderma in 2 (3%) and nonbullous ichthyosiform erythroderma was seen in 19 (31%). Generalized pruritus was present in 49 (80%) cases, atopic dermatitis in , elevated serum IgE level was noted in 27 and bronchial asthma in 3 cases. Dandruff was reported in 24 cases, keratosis pilaris in15, recurrent skin infection in 7. Combination of hereditary ichthyosis, generalized pruritus and high serum IGE level was reported in 27 (44.3%) patient.
Factors affecting the progression of diabetic nephropathy and its complications: A single-center experience in Saudi Arabia
Alwakeel Jamal,Isnani Arthur,Alsuwaida Abdulkareem,AlHarbi Ali
Annals of Saudi Medicine , 2011,
Abstract: Background and Objectives: One out of five Saudi diabetics develops end-stage renal disease (ESRD). Factors associated with progressive loss of renal function have not been extensively studied and reported in our community. We sought to evaluate the pattern and progression in glomerular filtration rate (GFR) and investigate the potential risk factors associated with progression to diabetic nephropathy (DN) among Saudi patients. Design and Setting: Hospital-based retrospective analysis of type 2 diabetic patients seen between January 1989 and January 2004 at Security Forces Hospital and King Saud University in Riyadh, Saudi Arabia. Patients and Methods: DN was defined as persistent proteinuria assessed by urine dipstick [at least twice for at least two consecutive years and/or serum creatinine >130 μmol/L; and/or GFR <60 mL/min/1.73m 2 ]. Results: Of 1952 files reviewed, 621 (31.8%) met the criteria for DN, and 294 (47%) were males. The mean (SD) age of the patients at baseline was 66.9 (11.4) years, and mean duration of diabetes was 15.4 (7.5) years. GFR deteriorated from a baseline value of 78.3 (30.3) mL/min/1.73m 2 to 45.1 (24.1) mL/min/1.73m 2 at the last visit, with a mean rate of decline in GFR of 3.3 mL/min/year. Progression of nephropathy was observed in 455 (73.3%) patients, with 250 (40.3%) patients doubling their first-hospital-visit serum creatinine level in a mean of 10.0 (6.0) years. At the end of the study, 16.5% of the cohort developed ESRD and were dialyzed. GFR >90 mL/min/1.73m 2 at the first hospital visit; duration of diabetes >10 years; persistent proteinuria; systolic blood pressure >130 mm Hg; and presence of retinopathy were significant markers associated with progression of nephropathy. Conclusion: Diabetic nephropathy tends to be progressive among Saudis, with GFR deteriorating at a rate of 3.3 mL/year and with a doubling of serum creatinine level in 40.3% of patients in 9.9 years.
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