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A rare cutaneous tumor of the axilla: Apocrine adenocarcinoma  [cached]
Karaca Semsettin,Kulac Mustafa,Sahin Onder,Esme Hidir
Indian Journal of Dermatology , 2007,
Abstract: Sweat gland neoplasms are rare with approximately 200 cases of eccrine sweat gland and less than 50 cases of apocrine gland carcinoma being reported in the worldwide literature. More than half of the reported cases with apocrine adenocarcinoma had lymph node metastases at the time of diagnosis. We report a case of a 56-year-old man, presented with a left axillary slow-growing seven year old painless nodule. Histopathological examination revealed an invasive apocrine adenocarcinoma with lymph node metastases. The patient successfully treated with total excision and radiotherapy. Apocrine adenocarcinoma is a rare malignancy with high metastatic potential that occurs mostly in the axilla. Physicians should be aware of this entity while differentiating cutaneous tumor located on the axillary region.
Calcifying Tumor of Malherbe  [cached]
Dr.Bharti Padmakar Baviskar,Dr. Ravindra Karle,Dr. Shubhangi Prashant Nigwekar,DR. SOMEN MISRA
International Journal of Biomedical and Advance Research , 2013, DOI: 10.7439/ijbar.v4i3.321
Abstract: ABSTRACT Tumours of the eyelid are not very common. Frequently we come across squamous cell carcinoma. We are reporting a rare case of calcifying epithelioma of eye. The usual presenting region is the hair bearing areas of body and upper extremity. A 15 years old male presented with swelling over upper lid. Clinically diagnosed as molluscum contagiosum. Surgical excision was carried out. Histopathology confirmed it as calcifying epithelioma of the eye. Epithelioma situated over the eyelid is very rare.
Ameloblastomatous calcifying odontogenic cyst; a case report
M Seyed-majidi,K Nosrati,S Haghanifar
Journal of Isfahan Dental School , 2009,
Abstract: Introduction: Calcifying odontogenic cyst (COC) is an uncommon developmental odontogenic cyst first described by Gorlin in 1962. It is considered as extremely rare and accounts for only 1% of jaw cysts reported. Because of its diverse histopathology, there has always been confusion about its nature as a cyst, neoplasm or hamartoma.Case Report: In this report, we present a rare case of calcifying odontogenic cyst with ameloblastic proliferation, an extremely rare histologic variant, in a 15 year old female in the left mandibular molar region. The lesion was surgically removed. After enucleation and curettage, no recurrence recorded in next two years.Conclusion: Ameloblastomatous calcifying odontogenic cyst, microscopically resembles unicystic ameloblastoma except for the ghost cells and dystrophic calcifications within the proliferative epithelium. There has always been confusion about its nature as a cyst, neoplasm or hamartoma. Microscopically, this cyst shows ameloblastic proliferation in the connective tissue but no characteristics of basal cell hyperchromatism, vacuolization and nuclear polarization which is often seen in ameloblastoma, are present here. Ameloblastoma ex COC and ameloblastomatous COC are morphologically and clinically entirely different and easily distinguishable.Key words: Calcifying odontogenic cyst, Ghost cell, Gorlin Cyst, Ameloblastic proliferation
Peripheral calcifying cystic odontogenic tumour of the maxillary gingiva
Ana Lima, Dárcio Kitakawa, Janete Almeida, Adriana Aigotti Brand?o, Ana Anbinder
BMC Research Notes , 2012, DOI: 10.1186/1756-0500-5-455
Abstract: Authors report a rare case of a peripheral calcifying cystic odontogenic tumor of the maxillary gingiva. A 39-year-old male patient presented with a fibrous mass on the attached buccal gingiva of the upper left cuspid teeth. It was 0.7-cm-diameter, painless and it was clinically diagnosed as a peripheral ossifying fibroma. After an excisional biopsy, the diagnosis was peripheric calcifying cystic odontogenic tumor. The patient was monitored for five years following the excision, and no recurrence was detected.All biopsy material must be sent for histological examination. If the histological examination of gingival lesions with innocuous appearance is not performed, the frequency of peripheral calcifying cystic odontogenic tumor and other peripheral odontogenic tumors may be underestimated.A calcifying cystic odontogenic tumor (CCOT) is an extremely rare benign cystic neoplasm that is characterized by an ameloblastoma-like epithelium and ghost cells that have the potential to undergo calcification [1]. Originally, CCOTs were referred to as calcifying odontogenic cysts (COC). The structure was first described by Gorlin in 1962 as a distinct entity and was therefore called Gorlin cyst [2]. COC was considered as a developmental odontogenic cyst in the jaw. In their first report, Gorlin et al. [2] considered this lesion to be a possible analogue of the cutaneous calcifying epithelioma of Malherbe (the pilomatrixoma). COC accounted for approximately 1% of jaw cysts. In 1981, Praetorius et al. [3] studied and reevaluated 16 cases of COC and proposed that the group actually contained two entities, a cyst and a neoplasm. Since then, neoplastic potential has been investigated.In 2005, the World Health Organization (WHO) designated Gorlin’s cyst as a tumor and described it as belonging to a group of related neoplasms, including the benign cystic-type (CCOT), the benign solid-type dentinogenic ghost cell tumor, and the malignant ghost cell odontogenic carcinoma [1]. The dentino
Anatomy of the Thoracic Wall, Axilla and Breast
Macéa,José Rafael; Fregnani,José Humberto Tavares Guerreiro;
International Journal of Morphology , 2006, DOI: 10.4067/S0717-95022006000500030
Abstract: for adequate treatment of patients with breast cancer, mastologists should have a complete understanding of the anatomy of the thoracic wall, axilla and breast. however, the classical anatomical descriptions in textbooks make it difficult to gain full mastery of this subject, because the books usually deal with its elements separately. in an endeavor to resolve this difficulty, the present authors have conducted an extensive review, to describe the muscles, blood vessels and nerves of the thoracic wall and in the axilla that are of interest to mastologists. the axilla was described in detail, with emphasis on its limits, walls and contents, and highlighting the lymph nodes in this region. finally, the anatomy of the breast and its topography, innervation, vascularization and lymph drainage were described, making correlations between the anatomy and the lymph node group classification routinely used by mastologists
Calcifying Epithelial Odontogenic Tumor  [PDF]
Olavo Hoston Gon?alves Pereira,Laura Priscila Barboza de Carvalho,Vilson Lacerda Brasileiro Junior,Cláudia Roberta Leite Vieira de Figueiredo
Case Reports in Pathology , 2013, DOI: 10.1155/2013/725380
Abstract: The calcifying epithelial odontogenic tumor (CEOT) is a rare benign epithelial odontogenic neoplasm of slow growth that is locally aggressive and tends to invade bone and adjacent soft tissue. Here is reported the case of a 21-year-old female patient with a CEOT in the left mandibular posterior region. The computerized tomography in coronal plane revealed a hypodense lesion in the posterior region of the left mandibular body with hyperdense areas inside and was associated with element 37. An incisional biopsy of the lesion was performed and the histopathological analysis revealed the presence of layers of epithelial odontogenic cells that formed prominent intercellular bridges. A large quantity of extracellular, eosinophilic, and amyloid-like material and an occasional formation of concentric calcifications (Liesegang rings) were also found. The histopathological diagnosis was a Pindborg tumor. Resection of the tumor with a safety margin was performed and after 6 months of follow-up there has been no sign of recurrence of the lesion. 1. Introduction The calcifying epithelial odontogenic tumor (CEOT) or Pindborg tumor is a rare benign epithelial odontogenic neoplasm [1, 2], with approximately 200 reported cases in the literature [3]. In general it occurs as a slow-growing tumor [4], associated with an impacted tooth in the posterior mandibular region [5, 6]. This occurs predominantly between the fourth and fifth decades of life, with no preference of gender [2–4]. Radiographically, CEOT is characterized by a uni- or multilocular lesion that often shows a mixed radiolucent-radiopaque pattern [6]. Treatment consists in the surgical removal of the lesion, with recurrence in 14% of cases [5]. The prognosis is considered good [6]. 2. Case Report A 21-year-old black female patient sought treatment at the Oral and Maxillofacial Trauma Surgery Unit, with swelling in the mandibular left posterior region. While performing the intraoral physical exam an asymptomatic hardened exophytic nodule was found in region 37 (Figure 1). Figure 1: Intraoral aspect of the lesion, characterized by a hardened nodular and exophytic mass in the mandibular body, on the left side. The patient reported a clinical evolution of only five months of the lesion. A radiographic exam revealed a diffuse radiolucent, unilocular lesion, associated with region 37, yet including the distal root of region 36 up to the crown of region 38 (Figure 2). Using a computerized tomography in coronal section, it was possible to observe that it was a question of a local hypodense lesion in the mandibular
Absence of musculocutaneous nerve in the left axilla
Virupaxi RD,Shirol VS,Desai SP,Ravishankar MV
International Journal of Anatomical Variations , 2009,
Abstract: Variations of the arrangement and distribution of the lateral cord and its branches in the infraclavicular part of the brachial plexus are common in one or both axillae. These variations are important to the surgeons, neurologists, anesthetists and anatomists during surgery and dissection in the region of axilla. The present case report describes the absence of musculocutaneous nerve in the infraclavicular part of left brachial plexus, observed during routine dissection of a 40-year-old male Indian cadaver. On the right side usual origin and course of musculocutaneous nerve was seen. The clinical importances of these variations are discussed.
Calcifying nanoparticles associated encrusted urinary bladder cystitis  [cached]
Tomislav M Jelic,Rod Roque,Uzay Yasar,Shayna B Tomchin
International Journal of Nanomedicine , 2008,
Abstract: Tomislav M Jelic1, Rod Roque1, Uzay Yasar2, Shayna B Tomchin1, Jose M Serrato2, Samuel G Deem3, James P Tierney3, Ho-Huang Chang11Department of Pathology Charleston Area Medical Center, Charleston WV, USA; 2Urology Center of Charleston, Charleston WV, USA; 3Urologic-Surgical Assoc. of Charleston, Charleston WV, USAAbstract: Encrusted cystitis is a subtype of chronic cystitis characterized by multiple calcifications in the form of plaques located in the interstitium of the urinary bladder mucosa and frequently associated with mucosal ulcers. It is a very rare disease of controversial etiology. Our transmission electron microscopy of the calcified plaques of encrusted cystitis has revealed that the smallest formed particles (elementary units) of these calcifications are electron-dense shells surrounding an electron lucent core, diagnostic of calcifying nanoparticles (previously called nanobacteria). We pioneer the notion that calcifying nanoparticles are the causative agents of encrusted urinary bladder cystitis.Keywords: calcifying nanoparticles, nanobacteria, encrusted cystitis
Calcifying epithelial odontogenic tumor: Report of two cases  [cached]
Mandal Shramana,Varma Kachnar,Khurana Nita,Mandal A
Indian Journal of Pathology and Microbiology , 2008,
Abstract: Calcifying epithelial odontogenic tumor (CEOT) is a rare, benign odontogenic tumor. It constitutes 0.4-3% of all odontogenic tumors. There is only a single case, which has been reported in the Indian literature that too in cytology. Microscopically, these are composed of large sheets of epithelial cells, amorphous amyloid-like material and calcification. Although these lesions are benign, they can be locally aggressive, but malignant transformation and metastasis is rare. Considering its locally aggressive nature, appropriate management and long-term follow-up is recommended. We describe two cases of CEOT involving the hard palate and leading to facial alterations.
Calcifying Ghost Cell Odontogenic Cyst: Report of a Case and Review of Literature
Archana Sonone,V. S. Sabane,Rajeev Desai
Case Reports in Dentistry , 2011, DOI: 10.1155/2011/328743
Abstract: The calcifying ghost cell odontogenic cyst (CGCOC) was first described by Gorlin et al. in 1962. Calcifying ghost cell odontogenic cyst is comparatively rare in occurrence, constituting about 0.37% to 2.1% of all odontogenic tumors. The most notable features of this pathologic entity are histopathological features which include a cystic lining demonstrating characteristic “Ghost” epithelial cells with a propensity to calcify. In addition, the CGCOC may be associated with other recognized odontogenic tumors, most commonly odontomas. There are variants of CGCOC according to clinical, histopathological, and radiological characteristics. Therefore a proper categorization of the cases is needed for better understanding of the pathogenesis of each variant. Here, we report a classical case of calcifying odontogenic cyst along with a brief review of literature.
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