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Constituintes químicos de Arrabidaea samydoides (Bignoniaceae)
Pauletti, Patrícia Mendon?a;Bolzani, Vanderlan da Silva;Young, Maria Claudia Marx;
Química Nova , 2003, DOI: 10.1590/S0100-40422003000500003
Abstract: chemical investigation of arrabidaea samydoides resulted in the isolation of the flavone chrysin; five triterpenes: lupeol, ursolic acid, 3b,16a-dihydroxy-urs-12-ene, uvaol, and erythrodiol; and two sterols: sitosterol and stigmasterol. the structures of these compounds were established by spectroscopic analysis. this paper deal with the first phytochemical study of arrabidaea samydoides.
Constituintes químicos de Arrabidaea samydoides (Bignoniaceae)  [cached]
Pauletti Patrícia Mendon?a,Bolzani Vanderlan da Silva,Young Maria Claudia Marx
Química Nova , 2003,
Abstract: Chemical investigation of Arrabidaea samydoides resulted in the isolation of the flavone chrysin; five triterpenes: lupeol, ursolic acid, 3b,16a-dihydroxy-urs-12-ene, uvaol, and erythrodiol; and two sterols: sitosterol and stigmasterol. The structures of these compounds were established by spectroscopic analysis. This paper deal with the first phytochemical study of Arrabidaea samydoides.
Antiviral activities of plants occurring in the state of Minas Gerais, Brazil: Part 2. Screening Bignoniaceae species
Brand?o, Geraldo Célio;Kroon, Erna G.;Santos, Jo?o Rodrigues dos;Stehmann, Jo?o Renato;Lombardi, Júlio A.;Oliveira, Alaíde Braga de;
Revista Brasileira de Farmacognosia , 2010, DOI: 10.1590/S0102-695X2010005000035
Abstract: ethanol extracts of eighteen bignoniaceae species have been evaluated by the mtt assay for cytotoxicity in vero cells and for antiviral activity against human herpes virus type 1, vaccinia virus and murine encephalomyocarditis virus. among such species, seven are reported to be of traditional medicinal use no cytotoxicity was observed for most of the extracts up to the concentration of 500 μg/ml. fourteen (50%) of the 28 extracts assayed have disclosed antiviral activity with ec50 values in the range of 4.6+0.3 to 377.2+17.7 μg/ml. only two species, arrabidaea samydoides and callichlamys latifolia, have shown activity against all the three viruses. the extracts were chemically characterized by their tlc and hplc-dad profiles. mangiferin is the major constituent of a. samydoides but the isolated compound has been less active than the crude extract. this is the first report on the antiviral evaluation of the eighteen bignoniaceae species assayed.
Antiviral activities of plants occurring in the state of Minas Gerais, Brazil: Part 2. Screening Bignoniaceae species Atividade antiviral de extratos de plantas coletadas no estado de Minas Gerais: Parte 2. Triagem de Bignoniaceae  [cached]
Geraldo Célio Brand?o,Erna G. Kroon,Jo?o Rodrigues dos Santos,Jo?o Renato Stehmann
Revista Brasileira de Farmacognosia , 2010,
Abstract: Ethanol extracts of eighteen Bignoniaceae species have been evaluated by the MTT assay for cytotoxicity in Vero cells and for antiviral activity against Human herpes virus type 1, Vaccinia virus and murine Encephalomyocarditis virus. Among such species, seven are reported to be of traditional medicinal use No cytotoxicity was observed for most of the extracts up to the concentration of 500 μg/mL. Fourteen (50%) of the 28 extracts assayed have disclosed antiviral activity with EC50 values in the range of 4.6+0.3 to 377.2+17.7 μg/mL. Only two species, Arrabidaea samydoides and Callichlamys latifolia, have shown activity against all the three viruses. The extracts were chemically characterized by their TLC and HPLC-DAD profiles. Mangiferin is the major constituent of A. samydoides but the isolated compound has been less active than the crude extract. This is the first report on the antiviral evaluation of the eighteen Bignoniaceae species assayed. Extratos etanólicos de dezoito espécies vegetais pertencentes à família Bignoniaceae, das quais sete s o descritas como de uso medicinal, foram avaliados, pelo ensaio colorimétrico do MTT, para atividades citotóxica, em células Vero, e antiviral, frente aos vírus herpes simplex-tipo 1, vaccinia e encefalomiocardite murina. A maior parte dos extratos n o apresentou citotoxicidade até a concentra o de 500 μg/mL. Dos 28 extratos testados quatorze (50%) apresentaram atividade antiviral com valores de CE50 na faixa de 4,6+03 a 377,2+17,7 μg/mL. Somente duas espécies, Arrabidaea samydoides e Callichlamys latifolia, foram ativas frente aos três vírus. Os extratos foram caracterizados pelos seus perfís cromatográficos em CCD e CLAE-FR. Análises por CLAE-FR mostraram que a mangiferina é o constituinte majoritário em A. samydoides mas a substancia isolada foi menos ativa do que o extrato bruto. Esta é a primeira vez que se relata a atividade antiviral de extratos das dezoito espécies avaliadas.
Diarreia em caprinos associada ao consumo de Arrabidaea corallina (Bignoniaceae)
Pessoa, Clarice R.M.;Medeiros, Rosane M.T.;Pess?a, André F. A.;Araújo, José A. de;Dantas, Ant?nio F.M.;Silva-Castro, Milene M.;Correa, Franklin Riet;
Pesquisa Veterinária Brasileira , 2010, DOI: 10.1590/S0100-736X2010000700006
Abstract: an outbreak of poisoning by arrabidaea corallina (jacq.) sandw. (fam. bignoniaceae) in goats is reported, which occurred in the municipality of boqueir?o, semiarid of paraíba, during the dry season. in a flock of 550 goats, older than one year of age, 56 (10%) were affected and 6 (1%) died. clinical signs were diarrhea, increased ruminal movements and depression. the goats recovered after being moved to another paddock. the pasture had low forage availability and large amounts of a. corallina was the only other green plant observed. one goat was necropsied. the gut had liquid, fetid and blackish content, and showed catarrhal enteritis. histology revealed acute, diffuse and moderate enteritis. eimeria sp. was also observed. non significant macroscopic or histological lesions were seen in other tissues. the disease was experimentally reproduced in four goats after the administration of fresh leaves of a. corallina, at 3-6 daily doses of 15g per kg of body weight. the animals showed diarrhea 3-4 days after the beginning of administration and recovered 5-6 days afterwards. it is concluded that the plant is responsible for the outbreak of diarrhea in goats, but parasitic disease or malnutrition can be contributing factors to the animal death. goats should be withdrawn from paddocks with a. corallina if during the dry seasons no other forage is available.
Varia??o da toxidez de Arrabidaea bilabiata (Bignoniaceae) em coelhos
Jabour, Flávia F.;Seixas, Josilene N.;Tokarnia, Carlos H.;Brito, Marilene F.;
Pesquisa Veterinária Brasileira , 2006, DOI: 10.1590/S0100-736X2006000300008
Abstract: the dried and powdered mature leaves and sprouts of arrabidaea bilabiata (fam. bignoniaceae), a liana or scandent shrub, were administered by stomach tube to 15 rabbits at doses of 0.25-6.0g/kg. the lowest dose of the sprouts collected in october (end of the dry season) causing death was 0.5g/kg, whilst the lowest lethal dose of sprouts collected in may (end of the rainy season) was 1.0g/kg. with the mature leaves collected in october the lowest lethal dose was of 4.0g/kg, and the lowest lethal dose of the mature leaves collected in may was 6.0g/kg. the clinical course of the poisoning was peracute. the rabbits all of a sudden fell down with struggling movements, difficult and spaced breathing, and died. at necropsy, significant alterations were not observed and histopatological examination showed, as the more important changes, vacuolar hydropic degeneration of epithelial cells of the distal convoluted renal tubules, diffuse vacuolation of the cytoplasm and necrosis of hepatocytes, presence of eosinophilic sphaerules in the sinusoids, groups of heart muscle fibers with increased eosinophilia, besides congestion in the kidneys, liver, heart and lungs. it was concluded that the toxicity of a. bilabiata varies according to the season of the year and the growth stage of the plant. the plant was most toxic in october and the sprouts were more toxic than the mature leaves, confirming the data previously obtained in experiments with cattle and buffalos.
Antimicrobial activity of a mixture of two isomeric phenylpropanoid glycosides from Arrabidaea harleyi A.H. Gentry (Bignoniaceae)
Lima, Cláudia Sampaio de Andrade;Amorim, Elba Lúcia Cavalcanti de;Sena, Kêsia Xisto da Fonseca Ribeiro de;Chiappeta, Alda de Andrade;Nunes, Xirley Pereira;Agra, Maria de Fátima;, Emidio Vasconcelos Leit?o da-Cunha;Silva, Marcelo Sobral da;Barbosa-Filho, José Maria;
Revista Brasileira de Ciências Farmacêuticas , 2003, DOI: 10.1590/S1516-93322003000100008
Abstract: arrabidaea harleyi a.h. gentry (bignoniaceae) is an ornamental plant found in some regions of the atlantic forest in brazil. from its bark a mixture of verbascoside and isoverbascoside was isolated. this mixture was shown to be active againststaphylococcus aureus, micrococcus luteus, bacillus subtilis, bacillus mycoides, enterecoccus faecalis, escherichia coli, serratia marcensisand candida albicans. the minimal inhibitory concentration (mic) was established by diffusion method.
Varia o da toxidez de Arrabidaea bilabiata (Bignoniaceae) em coelhos
Jabour Flávia F.,Seixas Josilene N.,Tokarnia Carlos H.,Brito Marilene F.
Pesquisa Veterinária Brasileira , 2006,
Abstract: A brota o e as folhas maduras dessecadas e trituradas de Arrabidaea bilabiata, um cipó ou arbusto escandente da família Bignoniaceae, foram administradas em suspens o aquosa por via intragástrica a 15 coelhos adultos nas doses que variaram de 0,25-6,0g/kg. Nos experimentos com a brota o coletada em outubro (fim da época de seca), a menor dose que causou a morte dos coelhos foi de 0,5g/kg e em maio (fim da época de cheia), a menor dose que causou a morte foi de 1,0g/kg. Já com as folhas maduras coletadas em outubro a menor dose que causou a morte dos coelhos foi de 4,0g/kg e em maio, a menor dose que causou a morte foi de 6,0g/kg. A evolu o em todos os casos letais foi superaguda. Clinicamente os coelhos de súbito debatiam-se com for a na gaiola, caiam em decúbito lateral ou esternal, faziam movimentos de pedalagem, apresentavam acentuada dispnéia e morriam. à necropsia n o foram observadas altera es significativas e ao exame histopatológico as les es mais importantes caracterizaram-se, nos rins, por degenera o hidrópico-vacuolar das células epiteliais dos túbulos contornados distais, no fígado por vacuoliza o difusa do citoplasma e necrose de hepatócitos, predominantemente centro-lobular e paracentral e presen a de esférulas eosinofílicas nos sinusóides hepáticos, no cora o, por grupos de fibras cardíacas com eosinofilia aumentada, além de congest o nos rins, fígado, cora o e pulm o. Neste estudo ficou estabelecido que a toxidez de A. bilabiata varia de acordo com a época do ano e o estado de matura o, pois essa planta foi mais tóxica em outubro e quando em brota o, confirmando, assim, os dados obtidos previamente em bovinos e búfalos.
EL GéNERO ARRABIDAEA (BIGNONIACEAE) EN ARGENTINA: NUEVOS REGISTROS, DISTRIBUCIóN Y FENOLOGíA
María Mercedes Arbo
Bonplandia , 2010,
Abstract: Las Bignoniaceae argentinas incluyen 23 géneros y 56 especies. Entre las lianas, Arrabidaea DC. es el género con mayor número de especies nativas. A.samydoides (Cham.) Sandwith, no conocida para Argentina, y A.triplinervia (DC.) Baill. ex Bureau, la cual fue citada, pero no documentada, ahora son descriptas e ilustradas. Se presenta una clave para identificar las nueve especies nativas. Se realiza un análisis comparativo de su distribución en Argentina y la fenología.
Análise farmacognóstica das folhas de Arrabidaea chica (Humb. & Bonpl.) B. Verlt., Bignoniaceae
Alves, Mauro Sérgio Marques;Mendes, Patrizia Cardoso;Vieira, Janaína Gell de Pontes;Ozela, Eliana Ferreira;Barbosa, Wagner Luiz Ramos;Silva Júnior, José Otávio Carréra;
Revista Brasileira de Farmacognosia , 2010, DOI: 10.1590/S0102-695X2010000200013
Abstract: arrabidaea chica (humb. & bonpl.) b. verlt. is a bignoniaceae widely used in the popular medicine as anti-inflammatory and astringent agent, and for some illnesses as intestinal colic, diarrhoeas, anaemia and diseases of the skin. its biological properties and dye biosynthesis lead the species to be used in the cosmetic industry. the use of natural products of vegetal origin implies in pharmacognostic quality control and purity assays that compose the technical specifications of the material. therefore, the anatomical description of mature and young leaves of a. chica was carried through the use of optic microscopy on histological preparations. the leaves are hipostomatic and dorsiventral with heterogeneous mesophile. in petiole, the epidermis is unistratified, it contains trachoma and it is endowed with thin cuticle. the pharmacopoeia assays included the determination of the grain size distribution of the plant drug, the determination of humidity and the total ashes, beyond the phytochemistry approach of tincture, to establish parameters for its quality control.
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