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Foundations for almost ring theory -- Release 6.9  [PDF]
Ofer Gabber,Lorenzo Ramero
Mathematics , 2004,
Abstract: This is release 6.9 of our project, aiming to provide a complete treatment of the foundations of almost ring theory, following and extending Faltings's method of "almost etale extensions". The central result is the "almost purity theorem". We are currently replacing Faltings's proof of the almost purity theorem by the new approach invented by Scholze, based on his perfectoid spaces. This is a transitional release : it provides the foundations for our generalization of Scholze's perfectoid spaces, and reduces the proof of the almost purity theorem to a general assertion concerning the \'etale topology of adic spaces, which will be proved in the next release. As usual, this new release is a mix of corrections and various improvements; almost all of the new material concerns the foundations of the theory of stacks and the accompanying 2-categorical preliminaries.
New developments in the treatment of primary insomnia in elderly patients: focus on prolonged-release melatonin [Corrigendum]
Cardinali DP, Vidal MF, Vigo DE
ChronoPhysiology and Therapy , 2013, DOI: http://dx.doi.org/10.2147/CPT.S42570
Abstract: New developments in the treatment of primary insomnia in elderly patients: focus on prolonged-release melatonin [Corrigendum] Corrigendum (319) Total Article Views Authors: Cardinali DP, Vidal MF, Vigo DE Published Date February 2013 Volume 2013:3 Pages 9 - 13 DOI: http://dx.doi.org/10.2147/CPT.S42570 Received: 09 January 2013 Accepted: Published: 11 February 2013 Cardinali DP, Vidal MF, Vigo DE. ChronoPhysiology and Therapy 2012, 2:67–79. Some of the references listed in Table 1 are incorrect. Read the original article Post to: Cannotea Citeulike Del.icio.us Facebook LinkedIn Twitter Other articles by Dr Daniel Cardinali New developments in the treatment of primary insomnia in elderly patients: focus on prolonged-release melatonin Readers of this article also read: Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor Radio electric asymmetric brain stimulation in the treatment of behavioral and psychiatric symptoms in Alzheimer disease Eye malformations in Cameroonian children: a clinical survey New developments in the treatment of primary insomnia in elderly patients: focus on prolonged-release melatonin Clinical applications of the Model for End-Stage Liver Disease (MELD) in hepatic medicine Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflammation and immune response mediators in tears from patients with dry eye disorders The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection The feasibility of a fiber optic laser approach to relieving lymphedematous syndrome: a case report Acute bilateral angle closure glaucoma induced by methazolamide Cubic phase nanoparticles for sustained release of ibuprofen formulation characterization and enhanced bioavailability study
New developments in the treatment of primary insomnia in elderly patients: focus on prolonged-release melatonin
Cardinali DP,Vidal MF,Vigo DE
ChronoPhysiology and Therapy , 2012,
Abstract: Daniel P Cardinali, María F Vidal, Daniel E VigoDepartment of Teaching and Research, Faculty of Medical Sciences, Pontificia Universidad Católica Argentina, Buenos Aires, ArgentinaAbstract: A temporal relationship between the nocturnal rise in melatonin secretion and the increase in sleep propensity at the beginning of the night, coupled with the sleep-promoting effects of exogenous melatonin, indicate that melatonin is involved in the regulation of sleep. This action is attributed to the MT1 and MT2 melatonin receptors present in the hypothalamic suprachiasmatic nucleus and other brain areas. The sleep-promoting actions of melatonin, which are demonstrable in healthy humans, have been found to be useful in subjects suffering from circadian rhythm sleep disorders and in elderly patients, who had low nocturnal melatonin production and secretion. The effectiveness of melatonin in treating sleep disturbances in these patients is relevant because the sleep-promoting compounds that are usually prescribed, such as benzodiazepines and related drugs, have many adverse effects, such as next-day hangover, dependence, and impairment of memory. Melatonin has been used for improving sleep in patients with insomnia mainly because it does not cause any hangover or show any addictive potential. However, there is a lack of consistency concerning its therapeutic value (partly because of its short half-life and the small quantities of melatonin used). Thus, attention has been focused either on the development of more potent melatonin analogs with prolonged effects or on the design of slow-release melatonin preparations. A prolonged-release preparation of melatonin 2 mg (Circadin ) has been approved for the treatment of primary insomnia in patients aged ≥55 years in the European Union. This prolonged-release preparation of melatonin had no effect on psychomotor functions, memory recall, or driving skills during the night or the next morning relative to placebo, and was associated with significantly less impairment on many of these tasks relative to zolpidem alone or in combination with prolonged-release melatonin. In 3-week and 6-month randomized, double-blind, clinical trials in patients with primary insomnia aged ≥55 years, prolonged-release melatonin was associated with improvements relative to placebo in many sleep and daytime parameters, including sleep quality and latency, morning alertness, and quality of life. Prolonged-release melatonin was very well tolerated in clinical trials in older patients, with a tolerability profile similar to that of placebo. Short-term
New developments in the treatment of primary insomnia in elderly patients: focus on prolonged-release melatonin
Cardinali DP, Vidal MF, Vigo DE
ChronoPhysiology and Therapy , 2012, DOI: http://dx.doi.org/10.2147/CPT.S15514
Abstract: evelopments in the treatment of primary insomnia in elderly patients: focus on prolonged-release melatonin Review (1143) Total Article Views Authors: Cardinali DP, Vidal MF, Vigo DE Published Date October 2012 Volume 2012:2 Pages 67 - 79 DOI: http://dx.doi.org/10.2147/CPT.S15514 Received: 07 August 2012 Accepted: 08 September 2012 Published: 12 October 2012 Daniel P Cardinali, María F Vidal, Daniel E Vigo Department of Teaching and Research, Faculty of Medical Sciences, Pontificia Universidad Católica Argentina, Buenos Aires, Argentina Abstract: A temporal relationship between the nocturnal rise in melatonin secretion and the increase in sleep propensity at the beginning of the night, coupled with the sleep-promoting effects of exogenous melatonin, indicate that melatonin is involved in the regulation of sleep. This action is attributed to the MT1 and MT2 melatonin receptors present in the hypothalamic suprachiasmatic nucleus and other brain areas. The sleep-promoting actions of melatonin, which are demonstrable in healthy humans, have been found to be useful in subjects suffering from circadian rhythm sleep disorders and in elderly patients, who had low nocturnal melatonin production and secretion. The effectiveness of melatonin in treating sleep disturbances in these patients is relevant because the sleep-promoting compounds that are usually prescribed, such as benzodiazepines and related drugs, have many adverse effects, such as next-day hangover, dependence, and impairment of memory. Melatonin has been used for improving sleep in patients with insomnia mainly because it does not cause any hangover or show any addictive potential. However, there is a lack of consistency concerning its therapeutic value (partly because of its short half-life and the small quantities of melatonin used). Thus, attention has been focused either on the development of more potent melatonin analogs with prolonged effects or on the design of slow-release melatonin preparations. A prolonged-release preparation of melatonin 2 mg (Circadin ) has been approved for the treatment of primary insomnia in patients aged ≥55 years in the European Union. This prolonged-release preparation of melatonin had no effect on psychomotor functions, memory recall, or driving skills during the night or the next morning relative to placebo, and was associated with significantly less impairment on many of these tasks relative to zolpidem alone or in combination with prolonged-release melatonin. In 3-week and 6-month randomized, double-blind, clinical trials in patients with primary insomnia aged ≥55 years, prolonged-release melatonin was associated with improvements relative to placebo in many sleep and daytime parameters, including sleep quality and latency, morning alertness, and quality of life. Prolonged-release melatonin was very well tolerated in clinical trials in older patients, with a tolerability profile similar to that of placebo. Short-term or longer-term treatment with prolonged
X-ray imaging of chemically active valence electrons during a pericyclic reaction  [PDF]
Timm Bredtmann,Misha Ivanov,Gopal Dixit
Physics , 2014, DOI: 10.1038/ncomms6589
Abstract: Time-resolved imaging of chemically active valence electron densities is a long sought goal, as these electrons dictate the course of chemical reactions. However, x-ray scattering is always dominated by the core and inert valence electrons, making time-resolved x-ray imaging of chemically active valence electron densities extremely challenging. To image such electron densities, we demonstrate an effective and robust method, which emphasizes the information encoded in weakly scattered photons. The degenerate Cope rearrangement of semibullvalene, a pericyclic reaction, is used as an example to visually illustrate our approach. Our work also provides experimental access to the long-standing problem of synchronous versus asynchronous bond formation and breaking during pericyclic reactions.
Silicone ring tourniquet versus pneumatic cuff tourniquet in carpal tunnel release: a randomized comparative study
G. I. Drosos,A. Ververidis,N. I. Stavropoulos,R. Mavropoulos,G. Tripsianis,K. Kazakos
Journal of Orthopaedics and Traumatology , 2013, DOI: 10.1007/s10195-012-0223-x
Abstract: According to the findings of this study, in patients who underwent carpal tunnel release under local anesthesia, the pain levels at the end of the operation and those just before the removal of the tourniquet were higher in the PT group than in the SRT group of patients.
Recent Developments with the licas System  [PDF]
Kieran Greer
Computer Science , 2014,
Abstract: This paper describes recent developments with the licas (lightweight Internet-based communication for autonomic services) software package. In particular, it describes how the architecture and functionality have changed from the first version release. The autonomous nature of the system is focused on, which requires independent behaviour and metadata descriptions of each service. The system has now also been ported to the Java mobile environment. Then some open questions or problems will be discussed in the areas of metadata consistency, security and trust. Finally, some solutions to these problems will also be suggested.
FAILURE ANALYSIS OF QUICK-RELEASE RING IN ENGINE AFTERBURNER DIFFUSER
发动机加力扩散器快卸环失效分析

XU Zhi-gang,LV Feng-jun,LI Quan Beijing Aeronautical Technology Research Center,Beijing,
徐志刚
,吕凤军,李权

腐蚀科学与防护技术 , 2009,
Abstract: During a routine inspection of an engine for troubleshooting,damages of crack and spall off are observed on an quick-release ring in an afterburner diffuser.In order to investigate the damage mechanism and failure causes,macroscopic and microscopic observations of the fractured surfaces and microstructure investigation have been performed.The results show that the crack of the quick-release ring is due to stress corrosion induced by intergranular corrosion,and the spall off from the surface of quick-release...
Almost ring theory - sixth release  [PDF]
Ofer Gabber,Lorenzo Ramero
Mathematics , 2002,
Abstract: We develop almost ring theory, which is a domain of mathematics somewhere halfway between ring theory and category theory (whence the difficulty of finding appropriate MSC-class numbers). We apply this theory to valuation theory and to p-adic analytic geometry. You should really have a look at the introductions (each chapter has one).
Apoptosis in Retinal Degeneration—Recent Developments  [PDF]
Magdalene J. Seiler
Open Journal of Apoptosis (OJApo) , 2014, DOI: 10.4236/ojapo.2014.31001
Abstract: Apoptosis in Retinal Degeneration—Recent Developments
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