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Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology  [PDF]
Zih-Rou Huang,Yin-Ku Lin,Jia-You Fang
Molecules , 2009, DOI: 10.3390/molecules14010540
Abstract: Squalene is a triterpene that is an intermediate in the cholesterol biosynthesis pathway. It was so named because of its occurrence in shark liver oil, which contains large quantities and is considered its richest source. However, it is widely distributed in nature, with reasonable amounts found in olive oil, palm oil, wheat-germ oil, amaranth oil, and rice bran oil. Squalene, the main component of skin surface polyunsaturated lipids, shows some advantages for the skin as an emollient and antioxidant, and for hydration and its antitumor activities. It is also used as a material in topically applied vehicles such as lipid emulsions and nanostructured lipid carriers (NLCs). Substances related to squalene, including β-carotene, coenzyme Q10 (ubiquinone) and vitamins A, E, and K, are also included in this review article to introduce their benefits to skin physiology. We summarize investigations performed in previous reports from both in vitro and in vivo models.
Ticks and Dermatology
Emine Dervi?
Turkderm , 2009,
Abstract: In 2002, cases with Crimean-Congo Haemorrhagic Fever (CCHF ) were diagnosed in Turkey and increasing numbers of those similar cases in following years have caused a big concern around the whole country. Because of the increasing numbers of patients referred to the dermatology clinics with tick related skin conditions or just with the need for a tick extraction, we found it necessary to review the recent information about ticks and tick-related skin diseases.
Book Review: Handbook of Paediatrics
RJ Green, I van Biljon
South African Journal of Child Health , 2011,
Abstract: Handbook of Paediatrics. 7th ed. Ed. by Cassim Motala. Section editors Alan Davidson, Anthony Figaji and Michael Levin. Soft cover. Pp xxv + 586. Illustrated. R449.95. Cape Town: Oxford University Press Southern Africa, 2010. ISBN 978-0-19-5991-17-8.
A-Z of Practical Paediatrics  [PDF]
Hemang Dixit
Kathmandu University Medical Journal , 2010, DOI: 10.3126/kumj.v8i2.3577
Abstract: A-Z of Practical Paediatrics Second Edition By Prof. Dr. Manindra R Baral Publisher: Educational Publishing House Jamal, Kathmandu Price: Rs. 600/-
Immunofluorescence In Dermatology  [cached]
Srinivas C.R,Alfred Sandra
Indian Journal of Dermatology , 1996,
Abstract: Immunofluorescence methods are commonly used in dermatology to demonstrate the presence of antibodies and immunoreactants in skin and serum. The various techniques, modifications, utility value and equipment require are briefly discussed.
Immunomodulators in Dermatology  [PDF]
Eda Kumbasar,Gonca G?kdemir,Adem K??lü
Turkderm , 2008,
Abstract: Immunomodulators include both immunostimulatory and immunosuppressive agents. The introduction of this new class of drugs marked the beginning of the post-cortisone era in clinical dermatology. Topical immunotherapy with both immunostimulatory and immunosuppressive agents show potential for effective treatment of inflammatory, infectious and neoplastic skin diseases. These agents have few side effects and have clinical effects similar to corticosteroids. The purpose of this review is to introduce to our collagues potentially useful immunomodulators in clinical dermatology. (Turkderm 2008; 42: 3-8)
Biologics in Dermatology  [PDF]
David Chandler,Anthony Bewley
Pharmaceuticals , 2013, DOI: 10.3390/ph6040557
Abstract: Skin and subcutaneous diseases affect millions of people worldwide, causing significant morbidity. Biologics are becoming increasingly useful for the treatment of many skin diseases, particularly as alternatives for patients who have failed to tolerate or respond to conventional systemic therapies. Biological therapies provide a targeted approach to treatment through interaction with specific components of the underlying immune and inflammatory disease processes. This review article examines the increasing evidence base for biologics in dermatology, including well-established treatments and novel agents.
Phenomena in dermatology  [cached]
Madke Bhushan,Doshi Bhavana,Pande Sushil,Khopkar Uday
Indian Journal of Dermatology, Venereology and Leprology , 2011,
Abstract: For a better understanding of various dermatoses, it is imperative for any physician practising dermatology to have a good theoretical knowledge of the underlying pathophysiologic processes involved in various systemic diseases involving the skin. For an easy grasp over this topic, we have discussed the various phenomena under three broad categories, like (a) clinical - Meyerson, Meirowsky, pathergy, Renbok, (b) laboratory - LE cell, prozone and (c) histopathology - Splendore-Hoeppli.
DermaMan: Scoring dermatology in your palm  [cached]
Eapen Bell
Indian Journal of Dermatology, Venereology and Leprology , 2008,
Abstract: Personal Digital Assistants (PDAs) have become a part of everyday life. DermaMan is a freely available, Java-based, dermatology-specific calculator for handheld devices. It includes modules to compute PASI, MASI, SCORAD, and for calculations related to topical PUVA and Botox administration.
Misoprostol in obstetrics and gynaecology — benefits and risks
G Essilfie-Appiah, GJ Hofmeyr, J Moodley
South African Journal of Obstetrics and Gynaecology , 2005,
Abstract: Misoprostol is currently being used for induction of labour at or near term and also for termination of pregnancy. Its use without proven dosage regimens is possibly associated with an increase in the incidence of uterine hyperstimulation, preterm labour, induced abortion above 20 weeks' gestation, meconium-stained liquor in the latent phase of labour, fetal distress and cases of uterine rupture as demonstrated by these case reports and literature review. Its use for these purposes must be under controlled circumstances, using minimum doses. South African Journal of Obstetrics and Gynaecology Vol.11(1) 2005: 9-10
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