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Short Communication - Mortality associated with cardiovascular diseases in three hospitals of Lomé-city
F Damorou, K Yayehd, S Pessinaba, T Tcherou, J Amonu
Pan African Medical Journal , 2011,
Abstract: The aims of present study were; to determine the mortality rate related to cardiovascular diseases and the causes of those deaths in local hospitals. We conducted a cross sectional study carried out from January 2005 to June 2006, in three hospitals of Lomé. All deaths registered in the departments of cardiology and neurology from cardiovascular diseases were taken into account. The number of patients who died from cardiovascular diseases was 200 on 2386 admitted patients (11.86%). The average age was 54.4 ± 15.6 years (range: 18-102). Cerebrovascular stroke was the most represented disease (56.9%), followed by heart failure (35.7%), and cardiac arrhythmias (15.9%). Hospital mortality due to cardiovascular afflictions was high in Lome-city due to the deficient organization of the cardiovascular resuscitation units. Better organization, more equipment for cardiovascular care units and better public health efforts surrounding control of cardiovascular risk factors could go a long way towards the reduction of this high mortality rate of cardiovascular diseases in our hospitals.
CARDIOVASCULAR BENEFITS AND POTENTIAL HAZARDS OF PHYSICAL EXERCISE IN ELDERLY PEOPLE
Mauri Kallinen
Journal of Sports Science and Medicine , 2005,
Abstract: Large and consistent beneficial effects with few adverse effects have been found in relation to physical exercise in selected samples of elderly subjects. However, thus far, it has not been confirmed to what extent the effects of physical exercise among elderly people are beneficial or even harmful in population-based studies. Additionally, the role of exercise testing among elderly people remains unclear. Firstly, the effects of prolonged physical training on cardiovascular fitness in 66-85-year-old women were examined in a cross-sectional study. Secondly, the predictive value of exercise-test status and results, including exercise capacity for survival, were studied in 75-year-old men and women. Thirdly, the effects of an endurance and strength training programme were examined in women aged 76 to 78 years in a population-based randomized controlled trial. Finally, the cardiac-adverse effects of acute exercise in the form of a cycle ergometer test were clarified in 75-year-old men and women. In the maximal exercise tests the mean peak oxygen uptake was respectively 26.2 and 18.7 ml·kg-1·min-1 among the physically active and less active control women. High cycling power (Watts per kg body weight) in the completed ergometer test was associated with decreased risk for death (multivariate HR 0.20; CI 0.08 - 0.50). The 18-week strength training resulted in a 9.4% increase in peak oxygen uptake while the endurance training improved peak oxygen uptake by 6.8%. A significant increase in cycling power in W/kg was found in the strength and endurance training groups compared to controls. Five cases of cardio- or cerebrovascular health problems emerged in the exercise training groups. These health problems were not directly related to physical exertion. In the final study 23 and 7% of the exercise tests in men and women, respectively, were prematurely terminated because of cardiac arrhythmia or ST segment depressions. Using various study designs and methods the effects of physical training on cardiovascular fitness were found to be beneficial among the four different samples of elderly people. High exercise capacity was found to be strongly and independently associated with decreased mortality among elderly men and women. Exercise testing provides information on the risk of death that is incremental to clinical data and traditional risk factors for death. Cardiovascular monitoring during exercise testing is recommended as a safety precaution. Cardio- or cerebrovascular health problems can occur during exercise training programmes involving elderly people, although
The Ideal Cardiovascular Health Metrics Associated Inversely with Mortality from All Causes and from Cardiovascular Diseases among Adults in a Northern Chinese Industrial City  [PDF]
Yan Liu, Hong-jie Chi, Liu-fu Cui, Xin-chun Yang, Yun-tao Wu, Zhe Huang, Hai-yan Zhao, Jing-sheng Gao, Shou-ling Wu, Jun Cai
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0089161
Abstract: Background and Aims The American Heart Association has recently established seven ideal cardiovascular health metrics for cardiovascular health promotion and disease reduction (i.e., non-smoking, normal body mass index, physically active, healthy diet, and normal levels of cholesterol, blood pressure and fasting blood glucose). The present study seeks to evaluate how well these metrics predict mortality from all causes and cardiovascular diseases in adult Chinese living in a northern industrial city. Methods and Results Data of 95,429 adults who participated in the Kailuan cohort study from June 2006 to October 2007 was analyzed. All participants underwent questionnaire assessment, clinical examination, laboratory assessments and were followed up biannually. During a median follow-up of 4.02 years, 1,843 deaths occurred, with 597 deaths resulting from cardiovascular diseases. Lower mortality rates from all causes and cardiovascular diseases were observed among the subjects who met a higher number of the ideal health metrics. Compared to the participants who met none or one ideal health metric, those meeting ≥5 ideal health metrics had a lower risk of all-cause mortality by 30% (adjusted hazard ratio, 0.70; 95% confidence interval, 0.56–0.88) and a lower risk of mortality from cardiovascular diseases by 39% (adjusted hazard ratio, 0.61; 95% confidence interval, 0.41–0.89) . Four metrics (smoking status, physical activity, blood pressure and fasting blood glucose) were significantly associated with all-cause mortality. Three metrics (physical activity, blood pressure and fasting blood glucose) were significantly associated with mortality from cardiovascular diseases. Conclusion The number of ideal health metrics is negatively associated with mortality rates from all causes and cardiovascular diseases among adults in a Northern Chinese industrial city. The data supports the AHA recommendation of ideal health metrics for adults from Northern China.
Cardiovascular diseases mortality in the population of Belgrade aged 30-69 years for 1990-2002 period  [PDF]
?ipeti? Sandra B.,Vlajinac Hristina D.,Stefanovi? Vesna,Stanisavljevi? Dejana
Vojnosanitetski Pregled , 2005, DOI: 10.2298/vsp0505343s
Abstract: During the period between 1990 and 2002 in Belgrade population, almost every second person aged 30-69 years, died of some cardiovascular disease (CVD). Men, as compared to women, had higher standardized mortality rates from CVD (1.7 times), ischemic heart diseases (2.5 times), other heart diseases (1.6 times), and cerebrovascular diseases (1.3 times). During that period, the mortality from CVD increased by 18.6% in men, and by 10.0% in women. The increase in cerebrovascular disease mortality was 32.6% for men and 17.2% for women. Mortality from ischemic heart disease decreased twice as much in men (17.0%) than in woman (8.5%). In both sexes, the average age-specific mortality rates from CVD creased with the age. In women, the average age-specific mortality rates were 5 years behind those in men. In both sexes aged 30-34 years, the average mortality rate from CVD increased by 22.2% in men and by 14.1% in women, respectively.
Trends in the risk of mortality due to cardiovascular diseases in five Brazilian geographic regions from 1979 to 1996
Souza, Maria de Fátima Marinho de;Timerman, Ari;Serrano Jr, Carlos Vicente;Santos, Raul D.;Mansur, Antonio de Pádua;
Arquivos Brasileiros de Cardiologia , 2001, DOI: 10.1590/S0066-782X2001001200007
Abstract: objective - to analyze the trends in risk of death due to cardiovascular diseases in the northern, northeastern, southern, southeastern, and central western brazilian geographic regions from 1979 to 1996. methods - data on mortality due to cardiovascular, cardiac ischemic, and cerebrovascular diseases in 5 brazilian geographic regions were obtained from the ministry of health. population estimates for the time period from 1978 to 1996 in the 5 brazilian geographic regions were calculated by interpolation with the lagrange method, based on the census data from 1970, 1980, 1991, and the population count of 1996, for each age bracket and sex. trends were analyzed with the multiple linear regression model. results - cardiovascular diseases showed a declining trend in the southern, southeastern, and northern brazilian geographic regions in all age brackets and for both sexes. in the northeastern and central western regions, an increasing trend in the risk of death due to cardiovascular diseases occurred, except for the age bracket from 30 to 39 years, which showed a slight reduction. this resulted from the trends of cardiac ischemic and cerebrovascular diseases. the analysis of the trend in the northeastern and northern regions was impaired by the great proportion of poorly defined causes of death. conclusion - the risk of death due to cardiovascular, cerebrovascular, and cardiac ischemic diseases decreased in the southern and southeastern regions, which are the most developed regions in the country, and increased in the least developed regions, mainly in the central western region.
Trends in the risk of mortality due to cardiovascular diseases in five Brazilian geographic regions from 1979 to 1996  [cached]
Souza Maria de Fátima Marinho de,Timerman Ari,Serrano Jr Carlos Vicente,Santos Raul D.
Arquivos Brasileiros de Cardiologia , 2001,
Abstract: OBJECTIVE - To analyze the trends in risk of death due to cardiovascular diseases in the northern, northeastern, southern, southeastern, and central western Brazilian geographic regions from 1979 to 1996. METHODS - Data on mortality due to cardiovascular, cardiac ischemic, and cerebrovascular diseases in 5 Brazilian geographic regions were obtained from the Ministry of Health. Population estimates for the time period from 1978 to 1996 in the 5 Brazilian geographic regions were calculated by interpolation with the Lagrange method, based on the census data from 1970, 1980, 1991, and the population count of 1996, for each age bracket and sex. Trends were analyzed with the multiple linear regression model. RESULTS - Cardiovascular diseases showed a declining trend in the southern, southeastern, and northern Brazilian geographic regions in all age brackets and for both sexes. In the northeastern and central western regions, an increasing trend in the risk of death due to cardiovascular diseases occurred, except for the age bracket from 30 to 39 years, which showed a slight reduction. This resulted from the trends of cardiac ischemic and cerebrovascular diseases. The analysis of the trend in the northeastern and northern regions was impaired by the great proportion of poorly defined causes of death. CONCLUSION - The risk of death due to cardiovascular, cerebrovascular, and cardiac ischemic diseases decreased in the southern and southeastern regions, which are the most developed regions in the country, and increased in the least developed regions, mainly in the central western region.
Asociación de la neuropatía autonómica cardiovascular y el intervalo QT prolongado con la morbimortalidad cardiovascular en pacientes con diabetes mellitus tipo 2 Association of cardiovascular autonomic neuropathy and prolonged QT interval with cardiovascular morbidity and mortality in patients with type 2 diabetes mellitus  [cached]
Ray Ticse Aguirre,Jaime E. Villena
Revista Peruana de Medicina Experimental y Salud Pública , 2011,
Abstract: Con el objetivo de evaluar la relación entre la neuropatía autonómica cardiovascular (NACV) y el intervalo QT corregido (QTc) con la morbimortalidad cardiovascular en pacientes con diabetes mellitus tipo 2, se realizó el seguimiento a 5 a os de 67 pacientes que acudieron a consulta externa del Servicio de Endocrinología. Se presentaron eventos cardiovasculares en 16 pacientes; el 82% completó el seguimiento y se encontró que el intervalo QTc prolongado fue la única variable que se asoció de forma significativa a morbimortalidad cardiovascular en el análisis de regresión logística múltiple (RR: 13,56; IC 95%: 2,01-91,36) (p=0,0074). In order to evaluate the relationship between cardiovascular autonomic neuropathy and corrected QT interval (QTc) with cardiovascular morbidity and mortality in patients with type 2 diabetes mellitus, we followed up for 5 years 67 patients attending the outpatient Endocrinology Service. 82% completed follow-up and cardiovascular events occurred in 16 patients. We found that long QTc interval was the only variable significantly associated with cardiovascular morbidity and mortality in the multiple logistic regression analysis (RR: 13.56, 95% CI: 2.01-91.36) (p = 0.0074).
Metabolic syndrome in Russian adults: associated factors and mortality from cardiovascular diseases and all causes
Oleg Sidorenkov, Odd Nilssen, Andrej M Grjibovski
BMC Public Health , 2010, DOI: 10.1186/1471-2458-10-582
Abstract: Data on 3555 adults aged 18-90 years were collected in a cross-sectional study in 2000. MetS was defined by the International Diabetes Federation (IDF) and National Cholesterol Education Program (NCEP) criteria. Sex-specific associations between the IDF-defined MetS, its components, and life-style, socio-economic factors and laboratory indicators, were analysed using multivariable Poisson regression. Vital status of the study participants was identified by July 2009. Sex-specific associations between MetS and stroke, Coronary Heart Disease (CHD), CVD and all-cause death, were studied by Poisson regression adjusted for age, smoking, alcohol and history of CVDs.After adjustment for all studied factors except BMI, age, serum GGT, C-reactive protein and AST-to-ALT ratio were associated with MetS in both genders. Additionally, MetS was associated with sedentary lifestyle in women and with smoking in men. In the same regression model drinking alcohol 2-4 times a month and consumption of five or more alcohol units at one occasion in men, and drinking alcohol 5 times or more a month in women were inversely associated with MetS. After a 9-year follow-up, MetS was associated with higher risk of death from stroke (RR = 3.76, 95% CI:1.35-10.46) and from either stroke or myocardial infarction (MI, RR = 2.87, 95% CI:1.32-6.23) in men. No associations between MetS and any of the studied causes of death were observed in women.Factors associated with MetS in both genders were age, GGT, C-reactive protein, and AST-to-ALT ratio. Moderate frequency of alcohol consumption and binge drinking in men and higher leisure time physical activity in women, were inversely associated with MetS.Positive associations between MetS and mortality were only observed for deaths from stroke and either stroke or MI in men.The metabolic syndrome (MetS) is a cluster of four major cardiovascular disease (CVD) risk factors; obesity, insulin resistance (hyperglycemia), arterial hypertension and dyslipidemia wh
Mortality pattern of cardiovascular diseases in the medical wards of a tertiary health centre in a rural area of Ekiti State, Southwest Nigeria.  [PDF]
Olarinde J Ogunmola, Antony O Akintomide
Asian Journal of Medical Sciences , 2013, DOI: 10.3126/ajms.v4i3.8030
Abstract: Objective : To determine the basic demographic patterns of cardiovascular diseases, deaths, and the frequency of clinical causes of deaths in medical wards of a tertiary health centre in a rural area, south west Nigeria. Materials and methods : Retrospective analysis of patients’ records admitted into the medical wards of Federal Medical Centre IdoEkiti, Ekiti State, South west Nigeria were conducted. The study subjects were patients of 16 years and above who died of cardiovascular diseases from January 2009 to December 2012. Data analysis was done using SPSS Version 16. Results: A total of 681 patients with cardiovascular diseases were admitted in medical wards within the study period, of which 70 died with crude mortality rate of 10.3%. Male mortality were 30 (42.9%) and females 40 (57.1%) ratio 1 : 1.3. The age range was 25 – 100 years with mean of 66.4 + 16.3 years, with more deaths occurring in the elderly (72%). The most frequent cause of deaths was stroke (68.6%). Conclusion : Females contributed the highest number of cardiovascular disease admission and crude mortality. Stroke was responsible for over half of cardiovascular deaths, and hypertension was the commonest aetiological factors of cardiovascular disease deaths. DOI: http://dx.doi.org/10.3126/ajms.v4i3.8030 Asian Journal of Medical Sciences 4(2013) 52-57
Estimated Glomerular Filtration Rate, All-Cause Mortality and Cardiovascular Diseases Incidence in a Low Risk Population: The MATISS Study  [PDF]
Chiara Donfrancesco, Simonetta Palleschi, Luigi Palmieri, Barbara Rossi, Cinzia Lo Noce, Fabio Pannozzo, Belinda Spoto, Giovanni Tripepi, Carmine Zoccali, Simona Giampaoli
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0078475
Abstract: Background Chronic kidney disease (CKD) independently increases the risk of death and cardiovascular disease (CVD) in the general population. However, the relationship between estimated glomerular filtration rate (eGFR) and CVD/death risk in a general population at low risk of CVD has not been explored so far. Design Baseline and longitudinal data of 1465 men and 1459 women aged 35-74 years participating to the MATISS study, an Italian general population cohort, were used to evaluate the role of eGFR in the prediction of all-cause mortality and incident CVD. Methods Bio-bank stored sera were used to evaluate eGFR at baseline. Serum creatinine was measured on thawed samples by means of an IDMS-calibrated enzymatic method. eGFR was calculated by the CKD-EPI formula. Results At baseline, less than 2% of enrolled persons had eGFR < 60 mL/min/1.73m2 and more than 70% had a 10-year cardiovascular risk score < 10%. In people 60 or more years old, the first and the last eGFR quintiles (<90 and ≥109 mL/min/1.73m2, respectively) were associated to an increased risk for both all-cause mortality (hazard ratio 1.6, 95% confidence interval 1.2-2.1 and 4.3, 1.6-11.7, respectively) and incident CVD (1.6, 1.0-2.4 and 7.0, 2.2-22.9, respectively), even if adjusted for classical risk factors. Conclusions These findings strongly suggest that in an elderly, general population at low risk of CVD and low prevalence of reduced renal filtration, even a modest eGFR reduction is related to all-cause mortality and CVD incidence, underlying the potential benefit to this population of considering eGFR for their risk prediction.
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