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Preventing intraperitoneal adhesions with vitamin E and sodium hyaluronate/carboxymethylcellulose: a comparative study in rats
Corrales, Fredy;Corrales, Marcelo;Schirmer, Carlos Cauduro;
Acta Cirurgica Brasileira , 2008, DOI: 10.1590/S0102-86502008000100007
Abstract: purpose: to compare the effectiveness of intraperitoneally administered vitamin e with the sodium hyaluronate/carboxymethylcellulose membrane (ha/cbmc) in preventing postoperative intraperitoneal adhesion formation. methods: sixty wistar rats underwent a laparotomy and adhesions were induced (ia). the animals were divided into four groups: group 1, control (ia); group 2 (ia + vitamin e): group 3 (ia+ha/cbmc) and group 4 (ia+ vitamin e + ha/cbmc). the vitamin e (groups 2 and 4) and ha/cbmc (groups 3 and 4) were administered intraperitoneally before the abdominal wall was closed. after 30 days, adhesions were classified by an independent surgeon. results: three animals died; one from group 3 and two from group 4. all control animals had substantial adhesions compared with unsubstantial adhesions observed in 11/15 in group 2 (p = 0.000), 11/14 in group 3 (p = 0.001), and 10/13 in group 4 (p = 0.000). conclusion: vitamin e, administered intraperitoneally, is as effective as ha/cbmc in preventing postoperative adhesions.
Effects of sodium hyaluronate and carboxymethylcellulose membrane on collagen and fibroblast formation in bowel suture healing: experimental study in rats
Perez, Ant?nio Carlos;Matos, Delcio;Montero, Edna Frasson de Souza;Souza, Heitor Soares de;Barbosa, Fábio Colagrossi Paes;Saad, Fabio;Dip, Nelson;
Acta Cirurgica Brasileira , 2005, DOI: 10.1590/S0102-86502005000100004
Abstract: purpose: to analyze the effects of sodium hyaluronate and carboxymethylcellulose membrane on collagen and fibroblast formation in bowel suture healing in rats. methods: 48 male wistar rats, weighing 250 to 343g, were randomized into two groups: group i - bowel suture without applying a biologically absorbable membrane and group ii - bowel suture with application of an absorbable membrane. the two groups were divided into subgroups of 3, 14 and 30 days of observation, with 8 rats in each subgroup. all were sacrificed after the end of the observation period. results: no morbidity or mortality was observed during the experiment. the amounts of collagen in group i were 23.4%, 72.1% and 67.6% and in group ii were 22.5%, 52.5% and 51.6%, for the subgroups of 3, 14 and 30 days, respectively. comparison between groups showed that the 14-day (p=0.0013) and 30-day (p=0.0587) subgroups had significant variance, with larger collagen zones in animals in which the membrane was not applied. however, with regard to fibroblasts, group i had 2%, 13% and 8% and group ii had 2%, 10% and 8%, for the 3-day (p=1.0), 14-day (p=0.3184) and 30-day (p=0.5995) subgroups, respectively, showing no significant variance. conclusion: the use of the biologically absorbable membrane cause a decrease in collagen formation, while not altering the number of fibroblasts, in bowel suture healing in rats, without increased morbidity and mortality.
Bloody tears (haemolacria)  [cached]
Ahluwalia B,Khurana A,Sood S
Indian Journal of Ophthalmology , 1987,
Abstract: A case of bloody tears in a young hysterical female is described and rarity of the condition is stressed.
Meniscal tears
Nicola Maffulli, Umile Giuseppe Longo, Stefano Campi, et al
Open Access Journal of Sports Medicine , 2010, DOI: http://dx.doi.org/10.2147/OAJSM.S7753
Abstract: iscal tears Mini-review (8405) Total Article Views Authors: Nicola Maffulli, Umile Giuseppe Longo, Stefano Campi, et al Published Date April 2010 Volume 2010:1 Pages 45 - 54 DOI: http://dx.doi.org/10.2147/OAJSM.S7753 Nicola Maffulli1, Umile Giuseppe Longo2, Stefano Campi2, Vincenzo Denaro2 1Centre for Sports and Exercise Medicine, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Mile End Hospital, London, England; 2Department of Orthopedic and Trauma Surgery, Campus Biomedico University, Via Alvaro del Portillo, Rome, Italy Abstract: The menisci are two semilunar-shaped fibrocartilagenous structures, which are interposed between the femoral condyles and tibial plateaux. They have an important role in knee function. Long-term follow-up studies showed that virtually all meniscectomized knees develop arthritic changes with time. The meniscus has functions in load bearing, load transmission, shock absorption, joint stability, joint lubrication, and joint congruity. Because of these functions, meniscal tissue should be preserved whenever possible. A well-trained surgeon can safely rely on clinical examination for diagnosing meniscal injuries. History and clinical examination are at least as accurate as magnetic resonance imaging in the skilled orthopedic surgeon’s hand. When meniscal repair is not possible, partial resection of the meniscus is indicated. Meniscal repair has evolved from open to arthroscopic techniques, which include the inside-out and outside-in suture repairs and the all-inside techniques. Meniscal transplantation is generally accepted as a management alternative option for selected symptomatic patients with previous complete or near-complete meniscectomy.
Glycerin as alternative solvent for the synthesis of Thiazoles  [PDF]
A. Venkat Narsaiah,Ramesh S. Ghogare,Dhanraj O. Biradar
Organic Communications , 2011,
Abstract: A variety of α-bromoketones undergoes smooth condensation with thiourea/ thioamide compounds to afford the corresponding substituted thiazole derivatives in excellent yields. The condensation reactions were carried out in a recyclable reaction medium glycerin without using any catalyst. All the reactions were completed within 2 hours of reaction time at room temperature.
Glycerin-A New Energy Source for Poultry  [PDF]
Y.N. Min,F. Yan,F.Z. Liu,C. Coto
International Journal of Poultry Science , 2010,
Abstract: Glycerin, known as glycerol or glycerine, is the principal co-product of biodiesel production, produced through a NaOH- or KOH-catalyzed transesterification of the triacylglycerols in oils or fats with an alcohol. Glycerin is known to be a valuable ingredient for producing food, soaps, cosmetics and pharmaceuticals. Currently, with plenty of glycerin available to the world market, more uses are expected to develop, especially as a potential energy source for poultry diets, with approximately 4,100 kcal/kg of gross energy. Moreover, glycerin also plays a critical role in body cellular metabolism. Results from different laboratories on the use of glycerin as feed energy source for poultry are discussed in this article. Positive responses are obtained with glycerol content up to 10% in poultry diets. The AMEn also has been measured in several experiments. However, more indices such as carcass performance and blood parameters need to be determined in further studies.
Optimization of Reaction Conditions for Preparing Carboxymethylcellulose  [PDF]
N.M. Ismail,A. Bono,A.C.R. Valintinus,S. Nilus
Journal of Applied Sciences , 2010,
Abstract: The cellulose powder was converted to carboxymethylcellulose (CMC) by etherification process using sodium monochloroacetate and sodium hydroxide. There are two reaction occur simultaneously during carboxymethylation that are the primary reaction which produces pure CMC and side reaction that produces undesired sodium glycolate. The carboxymethylation reaction was optimized against the reaction temperature, reaction time, SMCA concentration, NaOH concentration and the ratio solvent of ethanol:isopropanol. The Degree of Substitution (DS), viscosity and yield were analyzed with respect to the reaction conditions using response surface methodology. The method of analyzing the degree of substitution of CMC is back titration method. The produced CMC was identified by using Fourier Transform Infrared spectra (FTIR). The maximum DS obtained is 0.94, maximum yield is 22.0730 g and maximum viscosity 15.2 cP. After optimization of reaction conditions is carried out, the optimized DS obtained is 0.9424 and the optimized viscosity is 10.1 cP with yield is 22.1024 g.
The experience of using glycerin during processing of larval cyst cavity
Jamshed Shamsiev
Medical and Health Science Journal , 2010,
Abstract: The paper intends to determine what effect the hot glycerol has on the structure of the germinal cells and chitin shell as a whole; define how hot glycerin impacts the fibrous capsule and adjoining tissue. We made morphological study of excretory capsules and protoscoleces under influence of glycerin, which both had a room temperature and heated to a temperature of 600. Processing of larval cyst cavity by hot glycerin provides full destruction of chitin membrane: it shows how deep glycerin penetrates structures of fibrous capsule and delivers antiparasitic effect. Even using glycerin having room temperature leads to significant changes in structure of excretory capsules of protoscoleces. Morphological investigations showed that glycerin
Comparison of intraperitoneal honey and sodium hyaluronate-carboxymethylcellulose (SeprafilmTM) for the prevention of postoperative intra-abdominal adhesions
Emre, Arif;Akin, Murat;Isikgonul, Ipek;Yuksel, Osman;Anadol, Ahmet Ziya;Cifter, Cagatay;
Clinics , 2009, DOI: 10.1590/S1807-59322009000400016
Abstract: background: abdominal surgery can lead to postoperative intra-abdominal adhesions (piaas) with significant morbidity and mortality. this study compares the use of honey with a standard bioresorbable membrane (seprafilmtm) to prevent the formation of piaas in rats. methods: thirty rats underwent laparotomy, and piaas were induced by scraping the cecum. the animals were divided into three groups, each containing ten rats. group 1 (control) represented the cecal abrasion group, with no intraperitoneal administration of any substance. group 2 (honey group) underwent cecal abrasion and intraperitoneal administration of honey. group 3 (seprafilmtm group) underwent cecal abrasion and intraperitoneal seprafilmtm application. results: group 1 exhibited higher adhesion scores for adhesions between the abdominal wall and the organs. groups 2 and 3 had decreased adhesive attachments to the intra-abdominal structures. compared to group 1, the incidence of adhesion formation was lower in both group 2 (p=0.001) and group 3 (p=0.001). the incidence of fibrosis was also lower in group 2 (p=0.016) and group 3 (p=0.063) compared to group 1. there was no significant difference between the histopathological fibrosis scores for the rats in group 2 and those in group 3 (p= 0.688). conclusion: this study suggests that both honey and seprafilmtm decrease the incidence of piaas in the rat cecal abrasion model. although the mechanism of action is not clear, intraperitoneal administration of honey reduced piaas. the outcome of this study demonstrates that honey is as effective as seprafilmtm in preventing piaas.
Effect of Carboxymethylcellulose and Starch as Thickening Agents on the Quality of Tomato Ketchup  [PDF]
Md. Khayrul Alam,Maruf Ahmed,Mst. Sorifa Akter,Nurul Islam
Pakistan Journal of Nutrition , 2009,
Abstract: The objective of this study was to evaluate the effect of thickening agents such as carboxymethylcellulose and starch on the quality parameter of tomato ketchup during storage at 30°C. The carboxymethylcellulose was used at the rate of 0.75-1.25% while, starch was 3-4% in the formulation of tomato ketchup. The moisture content of ketchup was increased by the addition of both the thickening agents. The protein, fibre, ash, acidity and total soluble solid of tomato ketchup were decreased gradually when higher percentage of starch and carboxymethylcellulose were added. Amounts of lycopene, vitamin C and reducing sugar content were higher in the ketchup where starch was used. Starch and carboxymethylcellulose had <10 cfu/g of molds and total viable bacteria throughout storage at 30°C for 60 days. Carboxymethylcellulose treated ketchup was found more suitable than the starch treated through sensory evaluation.
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