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Primary Extranodal, Extralymphatic Hodgkin Lymphoma of the Mandible
Guido Ricardo Gonzalez-Fontal,Joaquin D. Rosales,Roberto Jaramillo,Andres F. Henao-Martinez
Case Reports in Medicine , 2011, DOI: 10.1155/2011/387570
Abstract: Primary extranodal, extralymphatic Hodgkin lymphomas (PEEHLs) are a rare occurrence. When they are encountered, they become diagnostic challenges. We are describing the uniqueness of a case of PEEHL affecting the mandible with his early response to the available chemotherapy.
Isolated involvement of the mandible by non-Hodgkin′s lymphoma.  [cached]
Sarda A,Kannan R,Gupta A,Mahajan V
Journal of Postgraduate Medicine , 1995,
Abstract: A case report of isolated involvement of the mandible by non-Hodgkin lymphoma is presented. The patient presented with a non-healing ulcer following a tooth extraction. Biopsy revealed an undifferentiated cancer. Investigations failed to reveal any involvement of the organs. A hemimandibulectomy was performed followed by radiotherapy on receipt of the histopathological diagnosis of non-Hodgkin lymphoma. The patient is asymptomatic two and a half years after treatment.
Primary Non-Hodgkin Lymphoma of The Cervix
Nasim Valizadeh,Haleh Ayatollahi,Siamak Naji
International Journal of Hematology-Oncology and Stem Cell Research , 2011,
Abstract: Background: There are only a few reports that exist regarding primary non-Hodgkin lymphoma of the genital tract. In this article, one case of primary B-cell type non-Hodgkin lymphoma (NHL) of the cervix is presented. Case history: A 45 year-old woman presented bloody vaginal discharge. Upon vaginal examination, the cervix was found to be enlarged. Cervical biopsy revealed B-cell type non-Hodgkin lymphoma. The patient was treated with CHOP chemotherapy. Conclusion: Systemic chemotherapy and radiation are recommended and effective treatments for genital tract B-cell type non-Hodgkin lymphoma.
Primary Thyroid Non-Hodgkin’s Lymphoma  [PDF]
Madiha Mahfoudhi, Khaled Khammassi, Imen Gorsane, Mounira El Euch, Sami Turki, Mamia Ben Salah, Taieb Ben Abdallah
Open Journal of Pathology (OJPathology) , 2015, DOI: 10.4236/ojpathology.2015.54015
Abstract: Primary non-Hodgkin’s lymphoma of the thyroid gland was rarely described. We report the case of a 44-year-old man admitted for an anterior neck swelling, hoarseness and dyspnea. The chest radiograph showed a trachea deviation. He had no clinical, biological or radiological sign of other lymphoma locations. Ultrasound examination of the neck revealed a bilateral heterogeneous thyroid lesion. Cytology revealed lymphoid cells having high nuclear-cytoplasmic ratio with multiple and irregular nucleoli. An urgent thyroid surgery consisting of total thyroidectomy had been performed since the presence of compressive signs due to the tumor. The histopathological examination of a biopsy from the thyroid tissue confirmed a high-grade non-Hodgkin’s lymphoma. Then, L-thyroxin substitution therapy, chemotherapy and radiotherapy were initiated. A prolonged remission was noted.
Primary Extranodal Non-Hodgkin’s Lymphoma Mimicking a Painful Gingival Swelling: A Case Report
Ayhan Tetik, Cem Peskersoy, Banu Ozveri Koyuncu, Murat Cihan Solmaz, Guray Saydam
Open Access Library Journal (OALib Journal) , 2016, DOI: 10.4236/oalib.1102363
Abstract: Diffuse large B cell lymphoma (DLBCL), the most common subtype of non-Hodgkin’s lymphoma (NHL), is an aggressive, rapidly growing neoplasm which is the most common lymphoid neoplasm affecting adults. Jaw involvement of NHL is rare, but among jaw lesions, the maxilla is more frequently involved than the mandible. Primary lymphoma of the mandible is often misdiagnosed clinically. A 43-year-old man admitted to the Ege University, Department of Oral and Maxillofacial Surgery at the Faculty of Dentistry with one month complaint of gingival pain and swelling in the left side of mandibular premolar area. Biopsy was planned and was done to send for histopathological examination. Histopathology by using immunohistochemistry techniques confirmed a diagnosis of a diffuse large B-cell lymphoma. In conclusion, dentists and oral maxillofacial surgeons who encounter patients with a suspicious oral lesion inconsistent with the presenting head/neck/face complaint, must include malignancy as part of their differential diagnosis.
Primary Extradural Non-Hodgkin's Lymphoma  [PDF]
Rakesh Kapoor, Vinay Kumar, S.C. Sharma
JK Science : Journal of Medical Education & Research , 2006,
Abstract: A 28 years old male presented to our institute with 3 months history of paraparesis with decreased sensationover left foot and loss of bladder and bowel control .The diagnostic work up revealed an extradural massat spinal level L3 L4.Had laminectomy and the tumour was sub totally resected. Histological examinationrevealed non hodgkin's lymphoma. The patient was worked up for disease anywhere else and was confirmedto have primary extra-dural non-hodgkin's lympoma(PENHL). Patient was treated with corticosteroides,adjuvant radiotherapy and chemotherapy. The residual tumour completely disappeared and patient isliving normal healthy life and is walking without support after 9 years of follow-up.
Primary non-Hodgkin’s lymphoma of the breast: a case report
Mangal Pandure, Ravindra Karle, Suryakant Dongre, Bharti Baviskar
Internet Journal of Medical Update - EJOURNAL , 2013,
Abstract: ABSTRACT: The breast is rarely a primary site for extranodal lymphoma. Majority of primary Non-Hodgkin’s lymphoma of breast occurring in younger age group are bilateral and those in older age group are unilateral. They are of B cell phenotype. We report a rare case of Primary Non-Hodgkin’s lymphoma of Breast-B cell phenotype diagnosed on fine needle aspiration cytology and confirmed by histopathological examination and immunohistochemical markers.
Primary non-Hodgkin’s lymphoma of the breast: a case report  [PDF]
Mangal Pandure,Ravindra Karle,Suryakant Dongre,Bharti Baviskar
Internet Journal of Medical Update - EJOURNAL , 2013,
Abstract: The breast is rarely a primary site for extranodal lymphoma. Majority of primary Non-Hodgkin’s lymphoma of breast occurring in younger age group are bilateral and those in older age group are unilateral. They are of B cell phenotype. We report a rare case of Primary Non-Hodgkin’s lymphoma of Breast-B cell phenotype diagnosed on fine needle aspiration cytology and confirmed by histopathological examination and immunohistochemical markers.
Primary non-hodgkin′s lymphoma of bone: Experience of a decade  [cached]
Qureshi Asim,Ali Anum,Riaz Nashmia,Pervez Shahid
Indian Journal of Pathology and Microbiology , 2010,
Abstract: Objective: To study the prevalence and characterization of primary non Hodgkin′s lymphoma of bone in a major referral center of Pakistan. Methodology: All cases of primary non Hodgkin′s lymphoma of bone, diagnosed at a referral center in Pakistan from January 1998 to July 2008 have been included. Patients with diagnosis of lymphoma at some other site prior to diagnosis in bone biopsy were excluded from the study. Results: Sixty cases of primary non Hodgkin′s lymphoma of bone were received, with a male to female ratio of 7: 3 (42 males and 18 females). Overall, 52/60 (86.6 %) patients were diagnosed with Diffuse large B-cell non-Hodgkin′s lymphoma. The largest fraction of patients was found in the pediatric group i.e. 33/60(55%) followed by elderly group i.e.15/60 (15%) and adults i.e. 12/60 (20%). The commonest sites of involvement were femur (28.3 %), hip bone (16.6%) and humerus (10%). Conclusion: Diffuse large B-cell lymphoma is the commonest type of primary non Hodgkin′s lymphoma of bone in the Pakistani population. It is common in all ages. The sites most often involved are femur followed by hip bone. Primary non Hodgkin′s lymphoma of bone appears to be more common in males. Our results are comparable to international data with various studies also showing that diffuse large B cell non Hodgkin lymphoma is the commonest primary bone lymphoma. However, primary Bone Lymphoma is more common in children and young adults.
Primary testicular non-Hodgkin's lymphoma: a review article
Bhatia, Komal;Vaid, Ashok Kumar;Gupta, Sachin;Doval, Dinesh Chandra;Talwar, Vineet;
Sao Paulo Medical Journal , 2007, DOI: 10.1590/S1516-31802007000500007
Abstract: primary testicular non-hodgkin's lymphoma was first described as a clinical entity in 1866. it is a rare disease and accounts for 1% of all non-hodgkin's lymphoma, 2% of all extranodal lymphomas and 5% of all testicular neoplasms. it is the most common testicular tumor in males between sixty and eighty years of age. testicular non-hodgkin's lymphoma is unique in its high incidence of bilateral involvement (8-38%), and it is also the most common bilateral testicular tumor. testicular non-hodgkin's lymphoma has a predilection for spreading to non-contiguous extranodal sites, especially the central nervous system. advanced-stage disease is usually managed with doxorubicin-based chemotherapy. for early-stage disease, opinion is divided regarding systemic chemotherapy following orchidectomy. the high incidence of spreading, especially to the central nervous system, leads to advocacy of the use of central nervous system prophylaxis with intrathecal chemotherapy. prospective multicenter trials incorporating a large number of patients may lead to better guidelines for optimal management of this subtype of non-hodgkin's lymphoma.
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