oalib
Search Results: 1 - 10 of 100 matches for " "
All listed articles are free for downloading (OA Articles)
Page 1 /100
Display every page Item
Syzygium jambolanum treatment improves survival in lethal sepsis induced in mice
Márcia CG Maciel, Jardel C Farias, Michele J Maluf, Eliane A Gomes, Paulo VS Pereira, Walmir C Arag?o-Filho, Josias B Fraz?o, Graciomar C Costa, Sanara M Sousa, Lucilene A Silva, Flávia MM Amaral, Momtchilo Russo, Rosane NM Guerra, Flávia RF Nascimento
BMC Complementary and Alternative Medicine , 2008, DOI: 10.1186/1472-6882-8-57
Abstract: C57Bl/6 mice were treated by the subcutaneous route with a hydroalcoholic extract from fresh leaves of S. jambolanum (HCE). After 6 h, a bacterial infection was induced in the peritoneum using the lethal CLP model. The mice were killed 12 h after the CLP induction to evaluate the cellular influx and local and systemic inflammatory mediators' production. Some animals were maintained alive to evaluate the survival rate.The prophylactic HCE treatment increased the mice survival, the neutrophil migration to infectious site, the spreading ability and the hydrogen peroxide release, but decreased the serum TNF and nitrite. Despite the increased migration and activation of peritoneal cells the HCE treatment did not decrease the number of CFU. The HCE treatment induced a significant decrease on the bone marrow cells number but did not alter the cell number of the spleen and lymph node.We conclude that the treatment with S. jambolanum has a potent prophylactic anti-septic effect that is not associated to a direct microbicidal effect but it is associated to a recruitment of activated neutrophils to the infectious site and to a diminished systemic inflammatory response.Many species have been used in the folk medicine to treat infectious diseases, and some of their anti-microbial activities have been proved. In fact, the anti-microbial activity has been recognized in different species of vegetal families, and this activity is usually due to the presence of secondary metabolites.Syzygium jambolanum DC. (syn:Syzygium cumini Skeels, Eugenia jambolana Lam.) is commonly known in Brazil as 'jambol?o', in India as Naval pazham and in English-speaking countries as jambolan, sweet olive or java plum. This species, from the myrtle family (Myrtaceae), has been used to treat illnesses caused by bacterial, fungal and viral pathogens [1], ulcers in genitourinary tract caused by Candida albicans, as well as cold, cough, fever and skin problems such as rashes and the mouth, throat and intestine
Crescimento inicial, níveis críticos de fósforo e fra??es fosfatadas em espécies florestais
FERNANDES, LUIZ ARNALDO;FURTINI NETO, ANTONIO EDUARDO;FONSECA, FERNANDO CAVICCHIOLI;DO VALE, FABIANO RIBEIRO;
Pesquisa Agropecuária Brasileira , 2000, DOI: 10.1590/S0100-204X2000000600016
Abstract: an experiment under greenhouse conditions was carried out at universidade federal de lavras, minas gerais state, brazil, to evaluate the growth of seedlings, phosphorus critical levels and phosphate fractions, in forest species growing under four phosphorus levels. seedlings of schinus terenbinthifolius raddi (aroeirinha), chorisia speciosa st. hill. (paineira) and syzygium jambolanum lam. (jambol?o) were cultivated on an oxisol fertilized with 0, 150, 300 and 600 mg dm-3 of p. the seedlings were harvested 180 days after germination and analysed for p forms. in all levels of phosphorus addition, the paineira produced higher aerial and root biomass than aroeirinha and jambol?o, and presented higher contents of organic phosphorus and higher relative participation of organic phosphorus in the total acid soluble phosphorus under all phosphorus levels. the improved growth rate of paineira was attributed to a greater efficiency in the metabolic adjustments of this species in relation to phosphorus nutrition, indicating that this species can grow in soils of variable p levels.
Evaluation of Syzygium jambolanum Methanolic Leaf Extract for Insulin-Like Properties
S.L. Lim,J.W. Chai,U.R. Kuppusamy
Research Journal of Biological Sciences , 2012,
Abstract: Traditionally, the fruits and seeds of Syzygium jambolanum (Lam.) DC [Family: Myrtaceae] have been used to treat diabetes mellitus. Insulin is known to inhibit lipolysis induced by epinephrine as well as promote lipogenesis and glucose uptake adipocytes. The present study evaluates the insulin-like properties of S. jambolanum leaf methanolic extract through lipogenic, anti-lipolytic and glucose uptake activities. Methanolic leaf extract of S. jambolanum induced significant lipogenesis in the dose range of 0.1-10 g mL 1 with the highest activity (114%) at 10 g mL 1. This extract (1 g mL 1 inhibited 29% of epinephrine (1 M) induced lipolysis and enhanced the inhibitory effect of insulin against epinephrine induced lipolysis. This extract also inhibited (64% inhibition) of isoproterenol (1 M) ( -adrenergic agonist) induced lipolysis. However, the extract did not enhance the antilipolytic action of propanolol ( -adrenergic antagonist). Thus, it is possible to speculate that the mode of action of this extract may involve competitive binding at -adrenergic receptor binding sites. S. jambolanum (0.1-10 g mL 1) exerted a dose-dependant glucose uptake activity and further enhanced insulin mediated glucose uptake in primary rat adipocytes. These results confirm that S. jambolanum methanolic leaf extract has insulin-like properties and may be useful as potential therapeutic agent in the management of hyperglycemia.
Evaluation of Syzygium jambolanum Methanolic Leaf Extract for Insulin-Like Properties
S.L. Lim,J.W. Chai,U.R. Kuppusamy
Research Journal of Biological Sciences , 2008,
Abstract: Traditionally, the fruits and seeds of Syzygium jambolanum (Lam.) DC [Family: Myrtaceae] have been used to treat diabetes mellitus. Insulin is known to inhibit lipolysis induced by epinephrine as well as promote lipogenesis and glucose uptake adipocytes. The present study evaluates the insulin-like properties of S. jambolanum leaf methanolic extract through lipogenic, anti-lipolytic and glucose uptake activities. Methanolic leaf extract of S. jambolanum induced significant lipogenesis in the dose range of 0.1-10 μg mL-1 with the highest activity (114%) at 10 μg mL-1. This extract (1 μg mL-1 inhibited 29% of epinephrine (1 μM) induced lipolysis and enhanced the inhibitory effect of insulin against epinephrine induced lipolysis. This extract also inhibited (64% inhibition) of isoproterenol (1 μM) ( -adrenergic agonist) induced lipolysis. However, the extract did not enhance the antilipolytic action of propanolol ( -adrenergic antagonist). Thus, it is possible to speculate that the mode of action of this extract may involve competitive binding at -adrenergic receptor binding sites. S. jambolanum (0.1-10 μg mL-1) exerted a dose-dependant glucose uptake activity and further enhanced insulin mediated glucose uptake in primary rat adipocytes. These results confirm that S. jambolanum methanolic leaf extract has insulin-like properties and may be useful as potential therapeutic agent in the management of hyperglycemia.
Ameliorative potentials of Syzygium jambolanum extract against arsenic-induced stress in L6 cells in vitro  [cached]
Asmita Samadder
Zhong Xi Yi Jie He Xue Bao , 2012,
Abstract: OBJECTIVE: To determine the ameliorative potentials of Syzygium jambolanum (SJ) extract in L6 skeletal muscle cells in regard to arsenic-induced impairment of optimum glucose homeostasis and improper functioning of mitochondria.METHODS: Several study parameters like glucose level and mitochondrial functioning through indexes of pyruvate kinase, glucokinase and mitochondrial membrane potential were assessed. The expression of the relevant marker proteins and mRNAs like glucose transporter 4 (GLUT4), insulin receptor substrate 1 (IRS1), IRS2 and glucokinase for tracking down the signalling cascade were critically analyzed.RESULTS: Introduction of SJ extract could bring about positive modulation of various markers, by acting on GLUT4, thereby bringing about an attenuation of the arsenite-induced toxic conditions in L6 cells.CONCLUSION: Syzygium jambolanum extract has considerable ameliorating potentials against arsenic-induced glucose imbalance and stress and has possibility of therapeutic use in the management of arsenic-induced toxicity including hyperglycemia.
Comparison between the effects of Syzygium jambolanum leaf and fruit extracts on estrogen positive and estrogen negative breast cancer cell lines.
U.M. Thliamplam,U.R.Kuppusamy,M.S. Kanthimathi,C. Wiart
International Journal of Molecular Medicine and Advance Sciences , 2011,
Abstract: Medicinal plants have widely been used to treat different kinds of ailments including cancer. Syzygium jambolanum, Linn (Myrtaceae) is a tropical plant used traditionally in the treatment of diabetes. However the effect of this plant on cancer has not been reported. Breast cancer is the most prevalent type of cancer among women and the incidence of this cancer has increased significantly around the world. In the present study, aqueous extract of S. jambolanum leaves and methanolic extract of its fruits were tested on breast cancer (MCF-7 and MDA-MB-231) cell lines for anti-proliferative effect. The MTT (3-[4,5-Dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay was used to quantitate the viable cells. The aqueous extract of S. jambolanum leaves and the methanolic extract of the fruits exerted dose-dependent inhibition (dose range of 100-500 μg/ml) on both cell lines. The leaf extract exerted more potent inhibitory effect on the MDA-MB-231 (estrogen negative) cell line as well as the MCF-7 (estrogen positive) compared with the methanolic extract of the fruit. The concentration of leaf extract that caused 50% inhibition (IC50) of MDA-MB-231 was 270 μg/ml. The IC50 for the rest of the incubations could not be determined.
Crescimento inicial, níveis críticos de fósforo e fra es fosfatadas em espécies florestais
FERNANDES LUIZ ARNALDO,FURTINI NETO ANTONIO EDUARDO,FONSECA FERNANDO CAVICCHIOLI,DO VALE FABIANO RIBEIRO
Pesquisa Agropecuária Brasileira , 2000,
Abstract: Foi conduzido um experimento em casa de vegeta o, com o objetivo de avaliar o crescimento de plantulas, os níveis críticos de P e algumas fra es fosfatadas, em três espécies florestais submetidas a quatro doses de P. Mudas de aroeirinha (Schinus terenbinthifolius Raddi), paineira (Chorisia speciosa St. Hill.) e jambol o (Syzygium jambolanum Lam.) foram cultivadas em um Latossolo Varia o Una, onde foram aplicados 0, 150, 300 e 600 mg dm-3 de P. Aos 180 dias após a germina o, as plantas foram colhidas e submetidas às análises químicas. Sob todas as doses de P, a paineira produziu maior biomassa da parte aérea e das raízes em compara o à aroeirinha e jambol o, além de apresentar maiores teores de P organico (Po) e maior participa o relativa do P organico (Po) em rela o ao P total solúvel em ácido em todos os níveis de fertiliza o fosfatada. O melhor crescimento da paineira foi atribuído a uma maior eficiência nos ajustes metabólicos desta espécie em rela o à nutri o fosfatada, o que indica que esta espécie pode ser plantada em solos com diferentes níveis de P.
Atividade antibacteriana de extrato hidro-alcoólico de folhas de jambol o (Syzygium cumini (L.) Skells)  [cached]
Loguercio Andrea Pinto,Battistin Alice,Vargas Agueda Castagna de,Henzel Andréia
Ciência Rural , 2005,
Abstract: A atividade antimicrobiana de plantas medicinais tem sido pesquisada em diversas espécies, tanto no Brasil quanto em outros países. O objetivo deste trabalho foi o de avaliar a existência de efeito antibacteriano de extrato hidro-alcoólico a 10% (m/v) de folhas de jambol o. Utilizaram-se 17 isolados bacterianos, Gram positivos e Gram negativos. A a o antibacteriana foi avaliada através da inocula o de placas de ágar Mueller Hinton, com um inóculo bacteriano de 1x10(6) ufc mL-1, onde se colocaram quatro discos de papel; o primeiro de antimicrobiano comercial e os demais embebidos em 25mL do extrato, de solu o salina ou de etanol. As placas foram incubadas a 37degreesC por 24 horas, sendo posteriormente realizada a leitura do diametro dos halos de inibi o. O extrato inibiu o crescimento de 100% das bactérias testadas e os isolados Gram positivos apresentaram um halo médio de 19,5mm, enquanto o dos Gram negativos foi de 18,8mm. N o houve inibi o significativa de crescimento nos tratamentos com salina e etanol. Conforme os resultados deste estudo, o extrato testado apresenta atividade antibacteriana frente às amostras testadas, sem diferen a de sensibilidade entre microrganismos Gram positivos e Gram negativos.
Níveis glicêmicos e de colesterol em ratos com Diabetes Mellitus aloxano induzido, tratados com infus?o de Bauhinia candicans ou Syzygium Jambolanum
Soares, Julio Cesar Mendes;Costa, Silvio Teixeira da;Cecim, Marcelo;
Ciência Rural , 2000, DOI: 10.1590/S0103-84782000000100018
Abstract: the present study verified the efficiency of two plants used in folk medicine for the reduction of hyperglycemia in diabetic people. sixty adult male wistar rats, with body weights ranging from 220 to 240g were treated with alloxan to induce insulin-dependent diabetes mellitus (iddm). two experiments were performed. in the first, 15 rats were treated with a single dose of alloxan (40mg/kg, i.p.); while in the second experiment animals received 60mg/kg, daily for three days. three days after the last injection, hyperglycemia was confirmed. positive animals were allocated into 3 groups of 5 and 15 rats for experiments i and ii, respectively. group 1 (c) was the control group, receiving standard rodent feed and water ad libitum. group 2 (ti) received rodent feed and an infusion of syzygium jambolanum ad libitum. group 3 (tii) received the feed and an infusion of bauhinia candicans. animals were treated for a period of 21 and 40 days for experiments i and ii respectively. blood was collected by retro orbital sinus puncture with animals under ether anesthesia on days 3, 9, 16, and 23 for experiment i; and days 3, 12, 24, and 40 for experiment ii. at the end of both experiments, all animals were euthanized and liver and pancreas samples were collected for light microscopy. all animals, in both experiments, had blood glucose levels above 170mg% on the third day after last alloxan injection. in the first experiment, plasma glucose was lower (p < 0.001) in ti as compared to c on day 23. in experiment ii, plasma glucose was lower in ti when compared to c on days 16 (p < 0.004) and 40 (p < 0.0001). moreover, clinical signs of iddm like polyfagya, polydpsya were attenuated in this group. plasma cholesterol showed a slight increase in all animals in experiment ii but no differences were observed between control and treated groups. histopathological analysis of pancreas and liver samples in the first experiment did not show marked differences between c and treated groups. however
Antimicrobial activity of Syzygium cumini (Myrtaceae) leaves extract
Oliveira, Guilherme Ferreira de;Furtado, Niege Ara?ari Jacometti Cardoso;Silva Filho, Ademar Alves da;Martins, Carlos Henrique Gomes;Bastos, Jairo Kenupp;Cunha, Wilson Roberto;Silva, Márcio Luís de Andrade e;
Brazilian Journal of Microbiology , 2007, DOI: 10.1590/S1517-83822007000200035
Abstract: the antimicrobial activity of syzygium cumini leaves extract, known as "jambol?o", was evaluated. the crude hydroalcoholic extract was active against candida krusei (inhibition zone of 14.7 ± 0.3 mm and mic = 70 μg/ml), and against multi-resistant strains of pseudomonas aeruginosa, klebsiella pneumoniae and staphylococcus aureus.
Page 1 /100
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.