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A PHARMACEUTICAL COMPARISON OF GUDUCHI GHRITA PREPARED FROM MALE AND FEMALE PLANTS OF TINOSPORA CORDIFOLIA (WILLD.) MIERS.  [PDF]
BK Ashok,Bhat Savitha D,PK Prajapati,B Ravishankar
International Journal of Research in Ayurveda and Pharmacy , 2011,
Abstract: Pharmaceutical study appreciates the importance of formulation preparation which ultimately determines the nature and magnitude of pharmacological activity expressed. Guduchi is one among the most important medicinal plants of India and various formulations of Guduchi ghrita are mentioned in different Ayurvedic classical texts. In the present study, a simple formulation of Guduchi ghrita which is used for treatment of chronic fever wherein no other ingredient except Guduchi was selected and a comparative pharmaceutical study of Guduchi ghrita prepared from male and female plants was carried out. The preparation of Guduchi ghrita formulations were carried out by adopting standard operative procedure. The result of this study shows that ghrita prepared from male plant yielded more quantity of finished product than that of female plant.
FORMULATION AND EVALUATION OF COMPOUND AYURVEDIC FORMULATION KRISHNADI CHURNA  [cached]
Saurabh Sharma,Satish Nayak,Sushil Mhaske
International Journal of Biomedical and Advance Research , 2012, DOI: 10.7439/ijbar.v2i12.211
Abstract: Quality assurance is an integral part and basic requirement for all the systems of medicines to ensure their quality of the formulation. Krishnadi Churna is one of the ancient Ayurvedic formulation consisting of five simple and valuable herbs. It consists of fine powder of dried fruits of Pippal, Ajwain, Bilva and rhizomes of Sonth and Nagarmotha in equal quantities. It is used in managing of GIT disturbances, nausea, vomiting and fever. In Ayurvedic formulation the main problem is lack of quality standards, there are batch-to-batch variation in the formulation. In present communication attempts have been formulation was prepared in laboratory according to procedure given in Ayurvedic Formulary of India. The ingredients were procured locally, identified and authentication was done. Formulation was subjected to physiochemical analysis, TLC profile and botanical characterization and compared using authentic ingredients as the references. Macroscopy, Microscopy and TLC profiling complement each other for the finding of the crude drugs are present in the formulation. The data is obtained from the analysis is adopted for detection, identification of Krishnadi Churna from other powdered drug formulations.
PHARMACOLOGICAL SCREENING OF AYURVEDIC ANTIHYPERLIPIDEMIC FORMULATION: AN AYURVEDIC APPROACH  [PDF]
Dadhania Sagar,Jani Dilip K.,Nirzarini N Shah
Journal of Pharmaceutical and Scientific Innovation , 2012,
Abstract: Doctrines of Ayurveda have momentous value even in the life of present day human life. These principles are based on the extraordinary observations and experimentations at various levels. Hence one cannot easily deny the observations put forward by the philosophers. According to one of its great preceptors Charaka- the dictum of Ayurveda is to maintain health of healthy people and to alleviate disorders in the diseased persons. The references of medicinal uses of herbs are recorded in Rgveda and Atharvaveda. Nighantus, the well-known compilations- are the very rich sources of herbal drug data ranging from identification, collection to therapeutics uses of the drugs.Since previous two decades there has been an increasing status emphasized on screening of herbs for hypolipidemic actions in order to reduce the risk of heart and other related disease. The high expenses and side effects of hyperlipidemia medications have led many populaces to search for alternate treatments. Only a few studies have been conducted to evaluate the effect of herbs mentioned in Ayurvedic texts on hyperlipidemia. Capparis Deciduas F., Ricinus Communis L., and Zizyphus Jujuba L. are traditionally used as antihyperlipidemic drugs as per Ayurvedic literature. Hence the present study was undertaken to investigate the antihyperlipidemic effect of a polyherbal formulation, prepared using the above three medicinal plants against Triton WR-1339 and High fat diet induced hyperlipidemia in rats. The probable mechanism of action of the extract may be inhibition of HMG-CoA reductase enzyme pathway.
STANDARDIZATION OF AYURVEDIC FORMULATION, PANCHSAKAR CHURNA  [cached]
Priyanka Soni,Vishal Soni,Shyam Shivhare,Arun Jha
Journal of Global Pharma Technology , 2010, DOI: 10.1234/jgpt.v2i2.123
Abstract: Ayurvedic medicine Panchsakar Churna is a combination of simple and routine use herbs even then their combined effect is great in managing constipation, haemorrhoids and pain in abdomen, flatulence, assimilatory disorder and rheumatic conditions. Through the Ayurvedic powder formulation enjoys great reputation, its standardization and quality control parameters are not well defined. The efforts have been initiated to develop certain methods and parameters for standardization and quality control. In house preparations (thee batches) of churna were prepared as per Siddhayog sangrah and the preparations are standardized according to guidelines of World Health Organization. viz extractive value, ash value, phytoconstituents, micromeritic parameter, volatile oil content etc. The results were found in close proximity of three batches. This study on Panchsakar churna was reproducible, precise and may be considered as a method for its quality control.
Standardisation of an Ayurvedic formulation "Sanjivani Vati"  [cached]
Parameswaran Sandhya,Mandar Nandan
International Journal of Green Pharmacy , 2010,
Abstract: Sanjivani vati is official in Ayurvedic formulary of India and is prescribed for the treatment of cough and fever. It is a polyherbal preparation containing ten ingredients. In this research paper, an attempt has been made to develop standardisation methods for some of the ingredients of Sanjivani vati. Quantitative estimation of tannins was done by Folin Denis method using gallic acid as standard. Embelin and Piperine were estimated by reverse phase HPLC. A standard laboratory reference sample of Sanjivani vati and two marketed samples were evaluated as per the developed method. The methods developed were validated in terms of linearity, accuracy, precision and recovery. Results indicated that only one marketed sample complied with all the standards prescribed and its content of tannin, piperine and embelin were equivalent to standard reference values.
Evaluation of an Ayurvedic Compound Formulation Laghusutasekhara Rasa  [PDF]
Om Prakash Rout,Rabinarayan Acharya,Rakshapal Gupta,Sagar Kumar Mishra
International Journal of Pharmaceutical and Phytopharmacological Research , 2013,
Abstract: ndia has vast heritage of traditional system of medicines, but due to lack of scientific evaluation, the people are unable to utilizethe benefits of it, particularly those people who cannot afford the modern medicine. The utmost efficacy of medicines as specifiedin Ayurvedic system can be achieved if each and every formulation mentioned inthesystem would be scientifically evaluated andtheir desired efficacy could be maintained. Therefore, an attempt has been made to evaluate Laghusutasekhara Rasa, anAyurvedic compound formulation used in various diseases. One sample from manufacture was procured and subjected tomacroscopic,microscopic, physico-chemical and TLC/HPTLC finger printing analysis using authentic ingredient as control.Microscopic and TLC/HPTLC finger printing analysis of the sample was found to complement each otherand are sufficient forestablishing the identityof raw materials in the compound formulation.
PHARMACOGNOSTIC AND ANALYTICAL STUDY OF DASHANGA KWATHA: AN AYURVEDIC FORMULATION
Baragi Umapati C.,Vyas Mahesh,Harisha CR,Baragi Pramod C.
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: This present study deals with pharmacognostic and analytical study of Dashanga Kwatha (A known Ayurvedic formulation used in Non Ulcer Dyspepsia). Here attempt was made to find out the authenticity of the drugs used in the formulation. This forms the first step in the standardization of a formulation. Herbal drugs, singularly or in combinations, contain numerous compounds in complex matrices in which no single active constituent is responsible for the overall efficacy. The pharmacognostic investigations were carried out in terms of organoleptic, microscopic, macroscopic examinations and the analytical study was carried in terms of physicochemical, phytochemical analysis and HPTLC examination by optimizing the solvent systems. Microbial load of dried powder material was determined to avoid the contamination and for safety of crude drug. The present work will provide referential information for the correct identification and standardization of the crude drug and will ensure the use of only genuine and uniform material in preparation of Dashanga Kwatha in future. These findings will be useful in establishing quality control standards and standardization of Dashanga Kwatha in future.
STANDARDIZATION OF AYURVEDIC POLYHERBAL FORMULATION: ANTIDIABETIC CHURNA  [PDF]
Nikam Shreya Pradeep,Alai Manoj H.,Meher Deepali Avinash
International Journal of Research in Ayurveda and Pharmacy , 2011,
Abstract: Ayurvedic medicine Anti-diabetic churna known to be effective in all types of madhumeha (Diabetes Mellitus) including polyuria, has been standardized by following modern scientific quality control procedures both for the raw material and the finished product. The obtained values of physical and chemical parameters can be adopted to lay down new pharmacopoeial standards to be followed for traditional preparation of Anti-diabetic churna with batch-to-batch consistency. The phytochemical constituents found to be present in the raw material used for the preparation of Anti-diabetic churna possibly facilitate the desirable therapeutic efficacy of the medicinal formulation, and also could help in knowing the underlying mechanisms of pharmacological action.
STANDARDIZATION OF A POLYHERBAL AYURVEDIC FORMULATION, SULAHARAN YOGA
Sahoo Rashmibala,Swain Pramod Kumar,Acharya Rabinarayana
International Journal of Research in Ayurveda and Pharmacy , 2011,
Abstract: The recent global resurgence of interest in traditional systems of medicines has led to an increase in the demand for them. These medicines are effective but commercialization of the manufacture of these medicines to meet this increasing demand has resulted in a decline in their quality, primarily due to lack of adequate regulations pertaining to this sector of medicine. The need of the hour is to evolve a systematic approach and to develop well-designed methodologies for the standardization of herbal formulations. In the paper, attempt has been made to evaluate Sulaharana Yoga, a Ayurvedic formulation. One sample was procured from manufactures and subjected to macroscopic, microscopic characterization, physico-chemical screening, thin layer chromatography (TLC) studies and was compared using in-house preparation formulation. It was observed that the commercial samples matched exactly with that of in-house preparation after performing the standardization.
STANDARDIZATION OF POLYHERBAL AYURVEDIC FORMULATION: CHANDANASAVA
Katekhaye Shankar,Singh Amritpal
International Journal of Research in Ayurveda and Pharmacy , 2011,
Abstract: The present paper deals with standardization of chandanasava, known to be effective in karsya (malnutrition), sukrameha (presence of semen in urine), mutrakrcchra (painful micturation), hrdroga (heart diseases), balaksaya (astringent), agnimandya (loss of appetite). Formulation has been standardized by following modern scientific quality control procedures for the finished product. Standardization of chandanasava was achieved by organoleptic study, physic-chemical analysis, thin layer chromatography, high performance thin layer chromatography (HPTLC). The obtained values of physical and chemical parameters can be adopted to lay down new pharmacopoeial standards to be followed for analysis of chandanasava to check batch to batch variation. Quantitative evaluation of gallic acid and apigenin in chandanasava by HPTLC had shown 25.12 μg/ml and 0.4 μg/ml respectively.
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