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Antioxidant and antibacterial activities of polyphenols from ethnomedicinal plants of Burkina Faso
Damintoti Karou, Mamoudou H Dicko, Jacques Simpore, Alfred S Traore
African Journal of Biotechnology , 2005,
Abstract: Polyphenols from four medicinal plants of Burkina Faso, Combretum micranthum, Khaya senegalensis, Pterocarpus erinaceus and Sida acuta, were screened for their antioxidant and antimicrobial activities against pathogenic bacteria. The medicinal plants displayed different polyphenols contents and antioxidant activities. The bark of P. erinaceus had the highest antioxidant activity. Some microorganisms were susceptible to polyphenol extracts with minimal bactericidal concentration values between 20 and 2000 mg/ml while other microorganisms appeared to be resistant to the extracts. Microbicide and microbiostatic activities of the extracts were dependent on the type of strains. Results suggest that these plants are not only interesting sources for antimicrobial activities but also potential sources of phenolic antioxidants.
Polyphenol Content and Antioxidant Activity of Fourteen Wild Edible Fruits from Burkina Faso  [PDF]
Aline Lamien-Meda,Charles Euloge Lamien,Moussa M.Y. Compaoré,Roland N.T. Meda,Martin Kiendrebeogo,Boukare Zeba,Jeanne F. Millogo,Odile G. Nacoulma
Molecules , 2008, DOI: 10.3390/molecules13030581
Abstract: A total of fourteen (14) species of wild edible fruits from Burkina Faso wereanalyzed for their phenolic and flavonoid contents, and their antioxidant activities usingthe DPPH, FRAP and ABTS methods. The data obtained show that the total phenolic andtotal flavonoid levels were significantly higher in the acetone than in the methanol extracts.Detarium microcarpum fruit had the highest phenolic and the highest flavonoid content,followed by that of Adansonia digitata, Ziziphus mauritiana, Ximenia americana andLannea microcarpa. Significant amounts of total phenolics were also detected in the otherfruit species in the following order of decreasing levels: Tamarindus indica > Sclerocaryabirrea > Dialium guineense > Gardenia erubescens > Diospyros mespiliformis > Parkiabiglobosa > Ficus sycomorus > Vitellaria paradoxa. Detarium microcarpum fruit alsoshowed the highest antioxidant activity using the three antioxidant assays. Fruits with highantioxidant activities were also found to possess high phenolic and flavonoid contents.There was a strong correlation between total phenolic and flavonoid levels and antioxidantactivities.
Antiacetylcholinesterase and antioxidant activity of essential oils from six medicinal plants from Burkina Faso
Kiendrebeogo, Martin;Coulibaly, Ahmed Y.;Nebie, Roger C. H.;Zeba, Boukaré;Lamien, Charles E.;Lamien-Meda, Aline;Nacoulma, Odile G.;
Revista Brasileira de Farmacognosia , 2011, DOI: 10.1590/S0102-695X2011005000008
Abstract: in this investigation, we evaluated essential oils from six medicinal plants from burkina faso for their antiacetylcholinesterase and antioxidant abilities. the chemotype of most active were also determined. the best antiacetylcholinesterase activities were recorded for the essential oils of eucalyptus camaldulensis (ic50 18.98 μ g/ml) and ocimum canum (ic50 36.16 μ g/ml). their chemotype have been related to the 1,8-cineole one. both essential oils demonstrated a linear mixed non competitive inhibition. the essential oil of ocimum basilicum which belong to the linalool-eugenol chemotype exhibited the best radical scavenging activity (ic50 3.82 μ g/ml) and reducing power (531.75 mg aae/g). in comparison with gallic and ascorbic acids, o. basilicum essential oil evidenced interesting antioxidant activities. the antiacetylcholinesterase and antioxidant activities of essential oils were discussed in regard with their chemical composition.
Antiacetylcholinesterase and antioxidant activity of essential oils from six medicinal plants from Burkina Faso  [cached]
Martin Kiendrebeogo,Ahmed Y. Coulibaly,Roger C. H. Nebie,Boukaré Zeba
Revista Brasileira de Farmacognosia , 2011,
Abstract: In this investigation, we evaluated essential oils from six medicinal plants from Burkina Faso for their antiacetylcholinesterase and antioxidant abilities. The chemotype of most active were also determined. The best antiacetylcholinesterase activities were recorded for the essential oils of Eucalyptus camaldulensis (IC50 18.98 μ g/mL) and Ocimum canum (IC50 36.16 μ g/mL). Their chemotype have been related to the 1,8-cineole one. Both essential oils demonstrated a linear mixed non competitive inhibition. The essential oil of Ocimum basilicum which belong to the linalool-eugenol chemotype exhibited the best radical scavenging activity (IC50 3.82 μ g/mL) and reducing power (531.75 mg AAE/g). In comparison with gallic and ascorbic acids, O. basilicum essential oil evidenced interesting antioxidant activities. The antiacetylcholinesterase and antioxidant activities of essential oils were discussed in regard with their chemical composition.
Antioxidant and Antibacterial Activities of Three Species of Lannea from Burkina Faso  [PDF]
L. Ouattara,J. Koudou,C. Zongo,N. Barro
Journal of Applied Sciences , 2011,
Abstract: The main goal of this study was to determine the phenol content, the antibacterial and the antioxidant activities of the three species of Lannea largely use in traditional medicine in Burkina Faso. The total phenolic and flavonoid contents of hydro alcoholic extract (70%V/V ethanol/distilled water) from the barks of Lannea acida, Lannea microcarpa and Lannea velutina (Anacardiaceae) were determined by the method of Folin Ciocalteu and AlCl3 by spectrophotometry. These extracts were tested for their antioxidant and antibacterial activities. Antioxidant activity was determined by the method of DPPH and compared with quercetin. Antibacterial activity was performed by disk diffusion and broth microdilution essays against nine reference bacterial strains including gram-positive and gram-negative bacteria. L.acida exhibited the highest total phenolic contents (40.55±0.26 g GAE/100 g) which correlated with better antioxidant activity (IC50 = 345.72±7.76 ?g mL-1). Furthermore the highest content of total flavonoids (11.02±0.04 g QE/100 g) and the largest anti bacterial spectrum (7.82 ?g mL-1?MIC? 62.5 ?g mL-1) were recorded with L.velutina. These results show that the barks of L. acida and L.velutina could be used respectively as a potential natural antioxidant and antibacterial agent.
Polyphenol Contents and Antioxidant Activities of Five Indigofera Species (Fabaceae) from Burkina Faso
S. Bakasso,A. Lamien-Meda,C.E. Lamien,M. Kiendrebeogo
Pakistan Journal of Biological Sciences , 2008,
Abstract: Aqueous acetone extracts prepared from five Indigofera species of Burkina Faso, namely Indigofera colutea (Burm.) Murril., I. macrocalyx Guilld et Perr., I. nigritana Hook f., I. pulchra willd. and I. tinctoria L., were investigated for their phytochemical composition and their antioxidant activities. Standard methods and TLC were used to screen the phytochemical composition. The total phenolic and flavonoid content of extracts were assessed by Folin-Ciocalteu and AlCl3 methods, respectively. These extracts were also evaluated for their antioxidant potentials using ferric reducing antioxidant power (FRAP), 2,2-diphenyl-l-picrylhydrazyl (DPPH) and 2,2`-azinobis(3-ethylbenzothiazoline-6-sulphonate) (ABTS) assays. Flavonoids, saponins, quinones, sterols/triterpenes and tannins were present in all these species except for I. pulchra where quinones were not found. Gallic acid, caffeic acid, rutin and myricetin in I. colutea; gallic acid, quercitrin, myricetin in I. tinctoria; galangin and myricetin in I. macrocalyx were identified by thin layer chromatography. Among these, I. colutea, I. tinctoria, I. nigritana and I. macrocalyx, which had the highest phenolic content, were also found to possess the best antioxidant activities. The results indicated a good correlation between antioxidant activities and total phenolic content (p<0.05 for FRAP/DPPH and DPPH/ABTS and p<0.01 for FRAP/ABTS). These plants represent promising sources of natural antioxidants and these findings give scientific bases to their ethnopharmacological uses.
Abortion in the North of Burkina Faso
Karl Lorenz Dehane
African Journal of Reproductive Health , 1999,
Abstract: Knowledge and use of abortifacients were investigated in a remote ethnically heterogeneous area in the north of Burkina Faso. A questionnaire survey was carried out among 320 married women in 21 villages and supplemented with key informants' interviews, clinical observations at the provincial hospital, and observations in one of the villages. Almost half of the sampled women of all ethnic groups admitted to the existence of abortion carried out by their peers. Response rates and knowledge of abortions were lower among younger women and among those belonging to the Islamic Hamallist and Wahabiya sects. Abortions were commonly induced by drinking a watery solution of the roots and leaves of a commonly found bush –– Securidaca longepedunculata. The plant contains uterine contraction stimulating ergot-alkaloids, but also strychnine-like toxic substances. It is reportedly effective in provoking abortions within one day of treatment, but its side-effects are severe and include heavy vaginal bleeding, abdominal pain, diarrhoea and vomiting, and death. There is a need for the rapid introduction of safer birth control methods in the region. (Afr J Reprod Health 1999; 3[2]: 40-50) Key Words: Burkina Faso, Fulbe, Gurmance, abortion, abortifacients, ergot-alkaloids
The rise of the “artist” in Burkina Faso
R Rousseau
Tydskrif vir letterkunde , 2007,
Abstract: It is only during the last twenty years that contemporary art has found actors in Burkina Faso. Thomas Sankara's revolutionary regime was the first to offer artists a frame to promote and perfect their technique. During the 1980s, the Semaine National de la Culture (National Week of Culture), the Pan-African Film Festival of Ouagadougou (Fespaco), and the Salon International de l'Artisanat de Ouagadougou (Ouagadougou International Handicraft Show) were the only major projects that allowed artists to learn new techniques and to be known. However, because Thomas Sankara's government expected the creators to participate in the revolutionary project, this left them little space for innovation and the expression of their artistic freedom. The early 1990s saw the rise of new events, which at last offered artists a space to practice their art, based on personal inspiration and competence in artistic technique. The Laongo symposium of granite sculpture, PIAMET (an event started by two well-known Burkinabè artists), and Ouaga'Art (organised by the French Cultural Centre of Ouagadougou) thus offered young artists the possibility of discovering the techniques of their colleagues from Africa and elsewhere in the world. However, except the Olorun Foundation, there is no permanent space dedicated to training and artistic exhibition. This lack is a source of obvious problems for the creator who, as a result, may find himself entrenched in a circuit where commercialism seems to dominate artistic research.
Nutraceutical Assessment of Four Amaranthus Species from Burkina Faso  [cached]
Ouedraogo Ibrahim,Hilou Adama,Sombie Pierre Alexandre Eric Djifaby,Compaore Moussa
Current Research Journal of Biological Sciences , 2011,
Abstract: The use of the amaranths as vegetables is developed in Burkina Faso. Most known are Amaranthus dubius Mart. Ex. Thell, Amaranthus graecizans L., Amaranthus hybridus L. and Amaranthus viridis L. A. hybridus is most used and abundantly cultivated, however the others are more or less wild. Theaim of the present study was to investigate the nutraceutical potentialities of four Amaranthus species from Burkina Faso. The aqueous decoction extract of the four species contains the highest ofpolyphenols, flavonoids,flavonols and proteins contents. The aqueous decoction extracts were used for the evaluation of the antioxidant activity and xanthine oxidase inhibitory potentiality. The A. dubius showed the most potent antioxidant activity with a CE50 of 1.26±0.46, mgm2 the β-carotene bleaching method. A. hybridus showed the most potent antioxidant activity (66.99±1.65 μmolAEAC/g) in the DPPH radical scavengingmethod. The aqueous extracts of the four speciesshowed weak inhibition of the xanthine oxidaseat the concentration of 200 μg/mL.The four Amaranthus species are rich in microelements (Na, K, Ca, Mg, P, Fe, Mn, Zn and Cu) and carotenoids compounds. The antinutritionals factors were also quantified. The oxalate amount in these species is fairly high. The highest minerals contents and the antioxidant activity of the amaranths could explain theirlarge use by all the socioeconomic strata of the population.These plants would constitute a source of dietetic antioxidants.
Prostate cancer outcome in Burkina Faso  [PDF]
Kabore Fasnéwindé A,Zango Barnabé,Sanou Adama,Yameogo Clotaire
Infectious Agents and Cancer , 2011, DOI: 10.1186/1750-9378-6-s2-s6
Abstract: Introduction African-American black men race is one of non-modifiable risk factors confirmed for prostate cancer. Many studies have been done in USA among African- American population to evaluate prostate cancer disparities. Compared to the USA very few data are available for prostate cancer in Sub-Saharan African countries. The objective of this study was to describe incident prostate cancer (PC) diagnosis characteristics in Burkina Faso (West Africa). Methods We performed a prospective non randomized patient’s cohort study of new prostate cancer cases diagnosed by histological analysis of transrectal prostate biopsies in Burkina Faso. Study participants included 166 patients recruited at the urology division of the university hospital of Ouagadougou. Age of the patients, clinical symptoms, digital rectal examination (DRE) result, serum prostate-specific antigen (PSA) level, histological characteristics and TNM classification were taking in account in this study. Results 166 transrectal prostate biopsies (TRPB) were performed based on high PSA level or abnormal DRE. The prostate cancer rate on those TRPB was 63, 8 % (n=106). The mean age of the patients was 71, 5 years (52 to 86). Urinary retention was the first clinical patterns of reference in our institution (55, 7 %, n = 59). Most patients, 56, 6 % (n = 60) had a serum PSA level over than 100 ng/ml. All the patients had adenocarcinoma on histological study of prostate biopsy cores. The majority of cases (54, 7 % n = 58) had Gleason score equal or higher than 7. Conclusion Prostate cancer is diagnosed at later stages in our country. Very high serum PSA level and poorly differentiated tumors are the two major characteristics of PC at the time of diagnosis.
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