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New bioactive metabolites produced by Phomopsis cassiae, an endophytic fungus in Cassia spectabilis
Silva, Geraldo H.;Teles, Helder L.;Trevisan, Henrique C.;Bolzani, Vanderlan da S.;Young, Maria C. M.;Pfenning, Ludwig H.;Eberlin, Marcos N.;Haddad, Renato;Costa-Neto, Claudio M.;Araújo, ?ngela R.;
Journal of the Brazilian Chemical Society , 2005, DOI: 10.1590/S0103-50532005000800029
Abstract: two new metabolites, ethyl 2,4-dihydroxy-5,6-dimethylbenzoate (1) and phomopsilactone (2) were isolated from phomopsis cassiae, an endophytic fungus in cassia spectabilis. their structures were elucidated by 1d and 2d nmr, ms and ir spectral data. compounds 1 and 2 displayed strong antifungal activity against the phytopatogenic fungi cladosporium cladosporioides and c. sphaerospermum, as well as cytotoxicity against human cervical tumor cell line (hela), in in vitro assays.
Effect of palm bunch ash on the seed germination, seedling growth and biochemical parameter of soybean
J Onwugbuta-Enyi, US Offor
Journal of Agriculture and Social Research (JASR) , 2010,
Abstract: The work was carried out to study the effects of Palm Bunch Ash (PBA) on seed germination, seedling growth and biochemical parameters of Soybean. Soybean seeds were raised in petri-dishes and irrigated with different concentrations of PBA (0-control, 10, 25,40,65,80 and 100%). At lower concentrations, PBA had promotory effects on all the parameters studied while 100% concentration had inhibitory effects.
Subramanian Deepika Priyadharshini,Venugopal Sujatha
International Research Journal of Pharmacy , 2011,
Abstract: Medicinal plants are source of important therapeutic aids for alleviating human ailments. The history of drug is intricately interowen with natural products for centuties. In tune with this effort, the objective set for the present investigation is to estimate the phenolic and flavonoid contents in flower extracts of Cassia auriculata and Cassia siamea. The preliminary qualitative screening revealed the presence of important secondary metabolites in both the species responsible for the antioxidant potential. Invitro assays to assess the antioxidant activities: DPPH- radical scavenging activity, reducing power, inhibition of lipid peroxidation gave fruitful results. Methanol extract of Cassia auriculata showed its superfluous scale comparatively higher with extracts of Cassia siamea. SC50/ EC50/ IC50 values calculated were also found to be significant for methanolic extract of Cassia auriculata, thus being in agreement with contents. Thus, the results of this study would certainly help to ascertain the potency of those extracts as potential source of natural antioxidants.
Polyarteritis nodosa  [cached]
Yelda Bilginer,Seza ?zen
Turk Pediatri Ar?ivi , 2008,
Abstract: Polyarteritis nodosa (PAN) is a necrotizing vasculitis affecting small and medium sized arteries. PAN occurs rarely during childhood. The clinical presentation is variable but symptoms and signs usually reflect the location of the inflamed vessels. PAN should always be in mind when a child presents with constitutional symptoms and multi-organ involvement. Although steroids and cyclophosphamide are the mainstays of therapy, randomized, multicenter, conrolled trials should allow clinicaians an evidence based approach to the treatment of these patients. (Turk Arch Ped 2008; 43 Suppl: 17-20)
Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus
Daisy P, Saipriya K
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S26650
Abstract: iochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus Original Research (3660) Total Article Views Authors: Daisy P, Saipriya K Published Date March 2012 Volume 2012:7 Pages 1189 - 1202 DOI: http://dx.doi.org/10.2147/IJN.S26650 Received: 30 September 2011 Accepted: 15 December 2011 Published: 07 March 2012 P Daisy, K Saipriya Postgraduate and Research Department of Biotechnology and Bioinformatics, Holy Cross College, Teppakulam, Trichy, Tamil Nadu, India Abstract: Cassia fistula stem bark was used for the preparation of aqueous extract and synthesis of gold nanoparticles to evaluate the hypoglycemic effects of the plant. The synthesized gold nanoparticles were characterized by ultraviolet-visible spectroscopy for their absorbance pattern, Fourier transform infrared spectroscopy to identify possible functional groups, and scanning electron microscopy to determine the size of the nanoparticles. The present investigation reports the efficacy of the gold nanoparticles as promising in the treatment of hyperglycemia. Body weight, serum glucose concentrations, liver function tests, kidney function tests, and lipid profile were analyzed. A significantly larger decrease in serum biochemistry parameters and an increase in body weight, total protein levels, and high-density lipoprotein were observed in rats with streptozotocin-induced diabetes treated with gold nanoparticles than in the ones treated with the aqueous extract. The results of this study confirm that C. fistula gold nanoparticles have promising antidiabetic properties.
Polyarteritis Nodosa
Z Nowroozi
Iranian Journal of Pediatrics , 1990,
Abstract: In this article 2 cases of polyarteritis Nodosa (PAN) are reported. The disease is a multisystem necrotizing vasculitis of small and medium-sized muscular arteries in which involvement of the renal and visceral arteries is characteristics. The etiology is unknown but HB antigenemia is found in 30% of patients. Drug exposures and hypersensitivity reactions are other possible causes. Microscopically the changes in the vessel may be divided into acute, healing and healed stages within the same case of classic PAN. One usually sees all 3 stages together. Clinical manifestations are variable because of different organ involvement but usually they Are nonspecific like fever, weight loss and pain. Excellent therapeutic results have been reported in classic PAN with the combination of corticosteroids and cytotoxic agents.
Cassia renigera Wall.: novo hospedeiro de Ceratocystis fimbriata Ell. & Halst.
Ribeiro, Ivan José Antunes;Ito, Margarida Fumiko;Rossetto, Carlos Jorge;
Bragantia , 1987, DOI: 10.1590/S0006-87051987000200021
Abstract: ceratocystis fimbriata ell. & halst. is described for the first time in 1984 on cassia renigera, in campinas, state of s?o paulo, brazil. in cross inoculation, the isolates of c. fimbriata obtained from cassia renigera and from mangifera indica showed pathogenicity to the following plants: acacia decurrens, theobroma cacao, crotalaria juncea, cajanus cajan, ficus carica, gmelina arborea, mangifera indica, hevea brasiliensis, cassia sp., c. carnaval, c. ferruginea, c. grandis, c. moschata, c. multijuga, c. nodosa, c. renigera, c. siamea and c. speciosa. the isolates of c. fimbriata were pathogenic to all tested plants, except for theobroma cacao, gmelina arborea and c. grandis.
Effects of Rumen Protected and Unprotected Choline on Energy-Related Biochemical Metabolites of Lactating Dairy Cows
A. Toghdory,T. Ghoorchi,A. Naserian,Y.J. Ahangari,S. Hassani
Journal of Animal and Veterinary Advances , 2012,
Abstract: Eight multiparous Holstein cows with an average milk production of 34.6±2.8 kg day-1 and body weight of 676±79 kg were used to evaluate the effect of rumen protected and unprotected choline on energy-related biochemical metabolites of lactating dairy cows. The experimental design was a balanced change over design with 4 treatments and 4 periods of 21 days. Experimental treatments were: No Choline (NC), Unprotected Choline (UC) fed at 50 g day-1, Rumen Protected Choline (RPC 25) fed at 25 g day-1 and Rumen Protected Choline (RPC 50) fed at 50 g day-1. Rumen protected choline was blended with 0.25 kg of ground corn and fed once per day as a top dress. Blood samples from coccygeal vessels were collected on last day of each period and analyzed for glucose, triglyceride, cholesterol, blood urea nitrogen, very low density lipoprotein, low density lipoprotein and high density lipoprotein. The result shows that blood metabolites such as glucose, triglyceride, cholesterol, blood urea nitrogen, very low density lipoprotein and low density lipoprotein not affected by treatments (p>0.05). Blood glucose concentration tendency increased by rumen protected and unprotected choline, but wasn t statistically significant. Unprotected choline decreased concentration of high density lipoprotein than control group (p<0.05). Rumen protected choline had no significant effect on high density lipoprotein levels. High density lipoprotein decreased by using unprotected choline, but other blood metabolites not changed by treatments.
Correlation between Body Condition Score, Blood Biochemical Metabolites, Milk Yield and Quality in Algerian Montbéliarde Cattle
Charef-Eddine Mouffok1,2,*, Toufik Madani1,2, Lounis Semara1, Nadhira Ayache1 and Amina Rahal1
Pakistan Veterinary Journal , 2013,
Abstract: This study aimed to investigate the correlation between body condition score (BCS), blood biochemical metabolites, milk yield (MY) and quality (Mfat) in Montbéliarde cattle (31 cows) reared in 5 farms of Algerian semi arid area. The BCS was measured in dry and peak of lactation (6 weeks after calving). Blood samples were taken at the time of body condition (BC) measurement for determination of energy (Glucose, cholesterol, triglycerides and B-Hydroxybutyrate), nitrogen (urea and albumin) and mineral (calcium) metabolites. Milk yield was recorded in the 6th week of lactation (peak). A sample of milk for each cow was used to determinate milk fat, density and acidity. The results showed a significant decrease in postpartum BCS accompanied by an increase in cholesterol and B-Hydroxybutyrate (BHB) concentration. The correlation analysis showed that BHB concentration in pre calving was negatively correlated with BCS (r=-0.321; P<0.05) and cholesterol (r=-0.308; P<0.05). In postpartum, BCS was negatively correlated with cholesterol (r=-0.416; P<0.05), urea (r=-0.366; P<0.05) and BHB (r=-0.487; P<0.05). However, the level of milk production decreased significantly with high glucose (r=-0.449; P<0.05) and BHB (r=-0.514; P<0.05). The fat content increased significantly with blood triglycerides (r=0.681; P<0.05) and BHB (r=0.522; P<0.05) concentration, indicating a high mobilization of body reserves used for the synthesis of milk fat. In conclusion, it can be assumed that the rate of BHB seems to be the best indicator of the nutritional status of dairy cows that determines their production level and quality.
Chauhan Neelam,Bairwa Ranjan,Sharma Komal,Chauhan Nootan
International Journal of Research in Ayurveda and Pharmacy , 2011,
Abstract: Cassia fistula Linn. commonly known as the Golden Shower, Indian Laburnum. It is native to India, the Amazon and Sri Lanka and diffused in various countries including Mexico, China, Mauritius, South Africa, East Africa, and West Indies. Medicinally it has been various pharmacological activities like antifungal, antioxidant, antimicrobial, anti inflammatory, anti-tumor, hepatoprotective, hypoglycemic activities. Further, studies reveal the presence of various phytochemical constituents mainly carbohydrates, proteins, fats, secondary metabolites. In traditional medicine, it is used in the treatment of hematemesis, pruritis, intestinal disorders, leucoderma, diabetes, & as antipyretic, analgesic & laxative. Its medicinal properties are recognized in Ayurvedic system of medicine. The herb Aragvadha is first mentioned in Charaka Samhita, and the action of Aragvadha as Kandughna and is Kusthaghna also firstly mentioned in the same classic.
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