oalib
Search Results: 1 - 10 of 100 matches for " "
All listed articles are free for downloading (OA Articles)
Page 1 /100
Display every page Item
Sarcoidosis infantil. Una rara enfermedad pediátrica: Caso clínico Childhood Sarcoidosis. A rare pediatric disease: Case report  [cached]
Israel Didier Cruz A,Sara Baron L,Claudia Garrido G,Jose Roberto Velazquez S
Revista chilena de pediatría , 2011,
Abstract: La sarcoidosis es un padecimiento multisistémico, de etiología desconocida. Afecta diversos órganos, entre los que se encuentran la piel, ojos, articulaciones, hígado, corazón, bazo y ganglios linfáticos. Los pulmones son el órgano más afectado en esta enfermedad, y aunque la sintomatología puede variar en cada etapa de la vida, lo común es que pase desapercibida en la mayoría de los casos. En algunos países como Inglaterra, Estado Unidos y Japón es endémica, en México y Latinoamérica su incidencia es baja. Existe una predisposición genética en la cual el complejo mayor de histocompatibilidad (HLA) tiene un papel predominante. El diagnóstico histopatológico requiere de la presencia en los tejidos de lesiones granulomatosas no caseificantes, células epiteloides e inclusiones citoplasmáticas llamadas células de Schaumann. La complicación más severa es la fibrosis pulmonar, por lo que el tratamiento con esteroides es de suma importancia. Presentamos el caso de un escolar al que se le realizo el diagnóstico de sarcoidosis pulmonar por biopsia pulmonar a cielo abierto. Al cual se le inicio tratamiento con esteroide sistémico y actualmente se encuentra bajo vigilancia, asintomático y sin complicaciones secundarias al tratamiento. Sarcoidosis is a systemic disease of unknown etiology. It affects various organs, including skin, eyes, joints, liver, heart, spleen and lymph nodes. Lungs are the organs most affected by this disorder and while symptomatology may vary thoughout life, most likely it is never diagnosed. It appears to be endemic in countries like England, US and Japan. The incidence is low in Mexico and Latin America. There is a genetic predisposition, where histocompatibility has a significant role. Histopathological diagnosis requires the presence of non-caseificating granulomatous lesions, with epiteloid cells with cytoplasmatic inclusions called Schaumann cells; these are diagnostic. The most severe complication is pulmonary fibrosis, which responds to steroids. We present the case of a schoolage child who was diagnosed as suffering from sarcoidosis after an open lung biopsy. Treatment with systemic steroids was initiated and is currenty asymptomatic, under observation and without complications secondary to treatment.
Childhood Sarcoidosis
Balameena S, Santh Ledge G, Panchapakesa Rajendran C, Porkodi R, Parthiban M
JK Science : Journal of Medical Education & Research , 2004,
Abstract: A case report of a young child who had presented with erythema nodosum, arthritis, uveitis, segmentallung lesion and was diagnosed as sarcoidosis has been projected, in which the role of fine needleaspiration biopsy has been highlighted.
Hydrocephalus, a rare manifestation of sarcoidosis  [cached]
Johan M. van Rooijen,Gerritje S. Mijnhout,Tom T.A. Aalders,R.B.J. de Bondt
Clinics and Practice , 2011, DOI: 10.4081/cp.2011.e66
Abstract: A 36-week-pregnant woman developed a symptomatic hydrocephalus. Chest imaging showed bihilar lymphadenopathy and histological examination of a mediastinal lymph node revealed non-caseating granulomas. After delivery, her neurologic complaints progressed. Placement of a ventriculoperitoneal drain (VPD) did not reduce the symptoms. However, steroids resulted in rapid disappearance of the hydrocephalus. Hydrocephalus is a very rare manifestation of sarcoidosis. The diagnosis relies on the ability of clinicians to recognize this disorder. This case shows how a difference in opinion of the several specialists involved can lead to a delay in diagnosis and treatment.
Hydrocephalus, a rare manifestation of sarcoidosis  [cached]
Johan M. van Rooijen,Gerritje S. Mijnhout,Tom T.A. Aalders,R.B.J. de Bondt
Clinics and Practice , 2011, DOI: 10.4081/cp.2011.e66
Abstract: A 36-week-pregnant woman developed a symptomatic hydrocephalus. Chest imaging showed bihilar lymphadenopathy and histological examination of a mediastinal lymph node revealed non-caseating granulomas. After delivery, her neurologic complaints progressed. Placement of a ventriculoperitoneal drain (VPD) did not reduce the symptoms. However, steroids resulted in rapid disappearance of the hydrocephalus. Hydrocephalus is a very rare manifestation of sarcoidosis. The diagnosis relies on the ability of clinicians to recognize this disorder. This case shows how a difference in opinion of the several specialists involved can lead to a delay in diagnosis and treatment.
Uterine Sarcoidosis: A Rare Extrapulmonary Site of Sarcoidosis  [PDF]
Creticus P. Marak,Narendrakumar Alappan,Amit Chopra,Olena Dorokhova,Sumita Sinha,Achuta K. Guddati
Case Reports in Rheumatology , 2013, DOI: 10.1155/2013/706738
Abstract: Sarcoidosis is a multisystem disease which is most commonly manifested in the pulmonary system. However, extrapulmonary manifestations have also been frequently reported. Isolated occurrence of sarcoidosis in the genital system is rare and poses a diagnostic and therapeutic dilemma. Uterine sarcoidosis can present with cervical erosions, endometrial polypoid lesions, and recurrent serometra. In majority of cases, it is diagnosed by endometrial curettage, but it has also been detected by examination of hysterectomy, polypectomy, and autopsy specimens. Nonnecrotizing granulomas are the characteristic pathologic finding of sarcoidosis. However, many infectious and noninfectious etiologies including certain neoplasms can produce similar granulomatous reactions in the female genital tract. These conditions affect the female genital tract more commonly than sarcoidosis, and therefore it is important to rule out these conditions first before making a diagnosis of sarcoidosis. Treatment of sarcoidosis is different from treating these other conditions and the most commonly used systemic or local corticosteroids can be hazardous if the underlying cause is infection. In this case report, the clinical presentation, histopathology, clinical course, and treatment of a patient with isolated uterine sarcoidosis are described, and a brief literature review of sarcoidosis of the female genital tract is provided. 1. Introduction Sarcoidosis is a multisystem disease of unclear etiology. Any organ system in the body can be affected by sarcoidosis, and the classic pathologic finding is the presence of noncaseating granulomas in the involved organs. Pulmonary sarcoidosis is the most common manifestation of the disease, accounting for 90 percent of the cases [1]. Extra pulmonary sarcoidosis is also common, with skin, eyes, liver, and reticuloendothelial manifestations accounting for the majority of the cases (10–25%). The involvement of other organ systems such as cardiovascular, nervous system, upper respiratory tract, renal, spleen, thyroid, gastrointestinal tract, musculoskeletal, and exocrine glands accounts for only a minority of cases (0.4–5%) [1–4]. Most of the cases with extra pulmonary sarcoidosis have coexisting pulmonary disease. This was shown by ACCESS research group where 368/736 (52%) of their patients had concomitant pulmonary involvement and only 14/736 (1.9%) of their patients had isolated extra pulmonary sarcoidosis [5]. Involvement of the female reproductive system by sarcoidosis is very rare. Unlike other extra pulmonary manifestations, there is not much
Sarcoidosis, Celiac Disease and Deep Venous Thrombosis: a Rare Association  [cached]
G?khan ?elik,Ayd?n ?ileda?,Onur Keskin,Arzu Ensari
Balkan Medical Journal , 2011,
Abstract: Sarcoidosis is a multisystem granulomatous disorder of unknown etiology and it may rarely be associated with a second disorder. Celiac disease is an immune-mediated enteropathy characterized with malabsorption caused by gluten intolerance, and several reports indicate an association between celiac disease and sarcoidosis. In addition, although celiac disease is associated with several extraintestinal pathologies, venous thrombosis has been rarely reported. Herein we present a rare case report of a patient with a diagnosis of sarcoidosis, celiac disease and deep venous thrombosis because of the rare association of these disorders. The patient was admitted with abdominal pain, weight loss, chronic diarrhea and a 5-day history of swelling in her right leg. A diagnosis of deep venous thrombosis was achieved by doppler ultrasonographic examination. The diagnosis of celiac disease was made by biopsy of duodenal mucosa and supported with elevated serum level of anti-gliadin IgA and IgG, and a diagnosis of sarcoidosis was achieved by transbronchial needle aspiration from the subcarinal lymph node during flexible bronchoscopy.
Sarcoidosis and IgA Nephropathy: a Rare Association
Canturk Tasci,Alper Gündo?an,Nesrin ?and?r,?lker Y?lmaz
Respiratory Case Reports , 2013, DOI: 10.5505/respircase.2013.35229
Abstract: Sarcoidosis a systemic chronic granulomatous disease characterized by noncaseating granulomas in the involvement organs. The etiology of the disease has yet to be precisely defined. The prevalence of sarcoidosis is 0.1-640 per one hundred thousand. In addition to the lungs, the other commonly involved organs are the skin, eyes, and joints. In previous investigations renal disorders were reported as 0.9% of sarcoidosis cases. In 50% of these cases, calcium metabolism disorders were found. However, proteinuria and hematuria are not common complications of sarcoidosis. This case report aims to argue for the rare association of sarcoidosis and IgA nephropathy, by presenting a case with proteinuria and IgA nephropathy in the renal biopsy.
Sarcoidosis of the spleen – rare indications for splenectomy. Own experience  [cached]
Marcin Bednarek,Piotr Budzyński,Andrzej Budzyński,Sergiusz Demczuk
Videosurgery and Other Miniinvasive Techniques , 2010,
Abstract: The article presents two patients who underwent laparoscopic splenectomy because of splenic sarcoidosis. In onepatient sarcoidosis was diagnosed based on the chest X-ray and computed tomography (CT) scans. Further imagingallowed for the diagnosis of systemic spread of the disease with bone marrow and splenic involvement. The latterlocation was confirmed by pathological examination after the operation. The indication for splenectomy was hypersplenismwith concurrent thrombocytopenia. In the second patient, an abdominal ultrasound scan (US) showed suspiciousfocal lesions in the spleen. Histological examination proved it to be a rare isolated splenic form of sarcoidosis.
Gastric Sarcoidosis: A Rare Clinical Presentation  [PDF]
Hemasri Tokala,Karthik Polsani,Jagadeesh K. Kalavakunta
Case Reports in Gastrointestinal Medicine , 2013, DOI: 10.1155/2013/260704
Abstract: Gastrointestinal (GI) sarcoidosis is a very rare disease, which clinically presents along with systemic disease or as an isolated finding. Gastric sarcoidosis is the most common form of GI sarcoidosis. Symptomatic gastric sarcoidosis is rare and only few case reports have been described in the literature with well-documented histological evidence of noncaseating granulomas. We present an interesting case of gastric sarcoidosis in a 39-year-old Caucasian man with symptoms of epigastric pain and profound weight loss. His endoscopic gastric mucosal biopsies revealed noncaseating granulomas consistent with gastric sarcoidosis. Treatment with oral steroids alleviated his symptoms with no recurrence in 2 years. Gastric sarcoidosis should be considered in patients with history of sarcoidosis and GI symptoms. 1. Introduction Sarcoidosis is a chronic noncaseating granulomatous systemic inflammatory disease. Even though it was first described by Sir Jonathan Hutchinson 140 years ago, to date the etiology is unclear [1]. It can involve any organ, with pulmonary involvement being the most common. Gastrointestinal (GI) involvement is very rare and may present along with systemic disease or as an isolated finding. Gastric sarcoidosis, first described by Schaumann in 1936, is the most common form of GI tract sarcoidosis [2]. Symptomatic GI involvement occurs only in 0.1 to 0.9% of patients with systemic disease [3]. In the literature there are only 26 reported cases of symptomatic gastric sarcoidosis with well-documented histological evidence of noncaseating granulomas consistent with sarcoidosis [4]. 2. Case Presentation A 39-year-old Caucasian man who is a race car driver by profession presented to the emergency department with a six-month history of nausea, vomiting, and profound weight loss along with one-month history of progressively increasing epigastric pain. His past history included incidental diagnosis of sarcoidosis in spleen and gall bladder one year ago when he met with a motor vehicle accident and underwent elective cholecystectomy and splenectomy. Physical examination was remarkable for mild tenderness in the epigastric region. Rest of the examination was unremarkable. Complete blood counts, comprehensive metabolic panel, and chest X-ray were normal. Computed tomography scan of the abdomen and pelvis revealed extensive adenopathy in the mesentery and retroperitoneum (Figure 1(b)). Esophagogastroduodenoscopy done during the hospital stay was significant for poor gastric insufflation and the wall of the stomach looked very rigid with diffuse erythema
Ichthyosiform sarcoidosis  [cached]
Gangopadhyay Asok
Indian Journal of Dermatology, Venereology and Leprology , 2001,
Abstract: A rare case of ichthyosiforn sarcoidosis is being reported.
Page 1 /100
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.