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Coriorretinopatía serosa central como manifestación extradigestiva de infección gástrica por helicobacter pylori
Asensio-Sánchez,V.M.; Rodríguez-Delgado,B.; García-Herrero,E.; Cabo-Vaquera,V.; García-Loygorri,C.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2008, DOI: 10.4321/S0365-66912008000300009
Abstract: objective: helicobacter pylori (hp) gastric infection has been implicated as an important factor in occlusive arterial pathology. nowadays, it is suspected that central serous chorioretinopathy (csc) is due to a multifocal vascular occlusive disease of the choriocapillaris. the aim of this study was to determine the relation between gastric hp infection and csc. materials and methods: we evaluated a group of 16 patients with csc and 20 controls. hp infection was assessed by the 13c-urea breath test (ubt). clinical csc diagnosis was confirmed by fundus biomicroscopy and fluorescein angiography. results: out of 16 patients with csc, 11 (68.75%) were males and 5 (31.25%) females, with a mean age of 46.3 years. hp infection was positive in 11 patients (68.75%) and negative in 5 (31.25%). men were hp-positive (hp+) in 72.7% of cases, compared to women who were hp+ in 60% of cases. the difference in prevalence of hp between the csc-group (68.75%) and the control-group (30%) was found to be statistically significant (p< 0.05). hp+ patients had more gastric pain than hp negative (hp-) patients (72.73% vs 20%). conclusions: these results indicate a possible statistical association between helicobacter pylori gastric infection and csc. hp should thus be considered a risk factor in csc patients.
Incidence of Helicobacter pylori in central serous chorioretinopathy: a case control study  [PDF]
Mostafa Feghhi,Eskandar Hajiani,Gholamreza Khataminia
Jundishapur Journal of Microbiology , 2008,
Abstract: Helicobacter pylori infection is one of the most common infections worldwide. Central serous chorioretinopathy (CSCR) is a serous macular detachment that usually affects young people. The aetiopathogenesis of the disease is still not completely understood. Recently, an interesting association has been observed between this disease and the H. pylori infection. This study was conducted to investigate a possible association between H. pylori infection and CSCR. A prospective study was performed and we evaluated a total of 54 CSCR patients (48 males and 6 females, median age 35.7 years), and a control group of 59 patients (25 women, 34 males; mean age 42.6±11 years) who referred to gastroenterology department of Imam Hospital, Ahvaz Jundishapur University of Medical Sciences, were studied. Central serous chorioretinopathy was diagnosed on the basis of findings in ophthalmic examinations and confirmed by fluorescein angiogram. All patients underwent a 13C-urea breath test (UBT) and serum IgG anti-bodies to H. pylori by enzyme-linked immunosorbent assay technique to detect H. pylori infection. Patients were defined as H. pylori infected if both tests were positive. The mean duration of symptoms before diagnosis was 10.5±4.5 days. Overall no statistically significant difference was found between left and right eyes, bilaterally was in 5 patients (9.2%). The incidence of H. pylori infection was 68.5% in CSCR patients and 65% in control subjects (p=0.64). These results indicate that the prevalence of H. pylori infection is not higher in patients with CSCR than in controls. Further large studies will be required to determine the role of H. pylori infection in patients with CSCR.
Helicobacter pylori infection is identified as a cardiovascular risk factor in Central Africans
Longo-Mbenza B, Nsenga JN, Mokondjimobe E, Gombet T, Assori IN, Ibara JR, Ellenga-Mbolla B, Vangu DN, Fuele SM
Vascular Health and Risk Management , 2012, DOI: http://dx.doi.org/10.2147/VHRM.S28680
Abstract: obacter pylori infection is identified as a cardiovascular risk factor in Central Africans Original Research (1368) Total Article Views Authors: Longo-Mbenza B, Nsenga JN, Mokondjimobe E, Gombet T, Assori IN, Ibara JR, Ellenga-Mbolla B, Vangu DN, Fuele SM Published Date August 2012 Volume 2012:8 Pages 455 - 461 DOI: http://dx.doi.org/10.2147/VHRM.S28680 Received: 29 November 2011 Accepted: 25 January 2012 Published: 15 August 2012 Benjamin Longo-Mbenza,1 Jacqueline Nkondi Nsenga,2 Etienne Mokondjimobe,3 Thierry Gombet,3 Itoua Ngaporo Assori,3 Jean Rosaire Ibara,3 Bertrand Ellenga-Mbolla,3 Dieudonné Ngoma Vangu,4 Simon Mbungu Fuele4 1Faculty of Health Sciences, Walter Sisulu University, Mthatha, South Africa; 2Division of Gastroenterology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo; 3Faculty of Health Sciences, University of Marien Ngouabi, Brazzaville, Democratic Republic of the Congo; 4Biostatistics Unit, Lomo Medical Center, Limete, Kinshasa, Democratic Republic of the Congo Background: Helicobacter pylori is now incriminated in the pathogenesis of atherosclerosis. Objective: To examine the importance of H. pylori infection as a cardiovascular disease (CVD) risk factor. Methods: Two hundred five patients (128 with H. pylori infection [HP-seropositive] and 77 without) had a baseline assessment for other potential CVD risk factors and were followed prospectively for 10 years (1999–2008). They were assessed on a monthly basis for the outcomes of carotid plaque, angina pectoris, myocardial infarction, and stroke. In the HP-seropositive group, male sex and quartile 4 for IgG anti-H. pylori antibodies (anti-HP Ab) were correlated with traditional CVD risk factors, stroke, myocardial infarction, and angina pectoris. Results: At the baseline assessment, the levels of carotid intima-media thickness, blood fibrinogen, total cholesterol, fasting plasma glucose, and uric acid were higher in H. pylori-infected patients than in the uninfected group. Serum HDL-cholesterol was significantly lower in the HP-seropositive group. Men had higher levels of IgG anti-HP Ab, waist circumference, blood pressure, uric acid, and total cholesterol than women. Within the HP-seropositive group, individuals in quartile 4 for IgG anti-HP Ab had higher rates of elevated fibrinogen, diabetes mellitus, low high-density lipoprotein cholesterol, arterial hypertension, and high total cholesterol than those in quartile 1. After adjusting for traditional CVD risk factors, H. pylori infection was the only independent predictor of incident carotid plaque (multivariate odds ratio [OR] = 2.3, 95% confidence interval [CI]: 1.2–7.2; P < 0.0001) and incident acute stroke (multivariate OR = 3.6, 95% CI: 1.4–8.2; P < 0.0001). Within the HP-seropositive group and after adjusting for traditional CVD risk factors, male sex was the only independent predictor of incident angina pectoris (multivariate OR = 3.5, 95% CI: 1.6–16; P < 0.0001), incident acute stroke (multivariate
Helicobacter pylori infection is identified as a cardiovascular risk factor in Central Africans  [cached]
Longo-Mbenza B,Nsenga JN,Mokondjimobe E,Gombet T
Vascular Health and Risk Management , 2012,
Abstract: Benjamin Longo-Mbenza,1 Jacqueline Nkondi Nsenga,2 Etienne Mokondjimobe,3 Thierry Gombet,3 Itoua Ngaporo Assori,3 Jean Rosaire Ibara,3 Bertrand Ellenga-Mbolla,3 Dieudonné Ngoma Vangu,4 Simon Mbungu Fuele41Faculty of Health Sciences, Walter Sisulu University, Mthatha, South Africa; 2Division of Gastroenterology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo; 3Faculty of Health Sciences, University of Marien Ngouabi, Brazzaville, Democratic Republic of the Congo; 4Biostatistics Unit, Lomo Medical Center, Limete, Kinshasa, Democratic Republic of the CongoBackground: Helicobacter pylori is now incriminated in the pathogenesis of atherosclerosis.Objective: To examine the importance of H. pylori infection as a cardiovascular disease (CVD) risk factor.Methods: Two hundred five patients (128 with H. pylori infection [HP-seropositive] and 77 without) had a baseline assessment for other potential CVD risk factors and were followed prospectively for 10 years (1999–2008). They were assessed on a monthly basis for the outcomes of carotid plaque, angina pectoris, myocardial infarction, and stroke. In the HP-seropositive group, male sex and quartile 4 for IgG anti-H. pylori antibodies (anti-HP Ab) were correlated with traditional CVD risk factors, stroke, myocardial infarction, and angina pectoris.Results: At the baseline assessment, the levels of carotid intima-media thickness, blood fibrinogen, total cholesterol, fasting plasma glucose, and uric acid were higher in H. pylori-infected patients than in the uninfected group. Serum HDL-cholesterol was significantly lower in the HP-seropositive group. Men had higher levels of IgG anti-HP Ab, waist circumference, blood pressure, uric acid, and total cholesterol than women. Within the HP-seropositive group, individuals in quartile 4 for IgG anti-HP Ab had higher rates of elevated fibrinogen, diabetes mellitus, low high-density lipoprotein cholesterol, arterial hypertension, and high total cholesterol than those in quartile 1. After adjusting for traditional CVD risk factors, H. pylori infection was the only independent predictor of incident carotid plaque (multivariate odds ratio [OR] = 2.3, 95% confidence interval [CI]: 1.2–7.2; P < 0.0001) and incident acute stroke (multivariate OR = 3.6, 95% CI: 1.4–8.2; P < 0.0001). Within the HP-seropositive group and after adjusting for traditional CVD risk factors, male sex was the only independent predictor of incident angina pectoris (multivariate OR = 3.5, 95% CI: 1.6–16; P < 0.0001), incident acute stroke (multivariate OR = 3.2, 95% CI: 1.4–28; P < 0.0001),
Frecuencia de Helicobacter pylori en diabéticos tipo 2
Hernández Ortega,Ania; Sánchez Cruz,Julio César; Umpierrez García (2),Ibis;
Revista M??dica Electr?3nica , 2010,
Abstract: helicobacter pylori is a bacteria related with the peptic ulcerous disease, the adenocarcinoma, the gastric malt lymphoma and other extradigestive diseases, diabetic mellitus type 2 among them, where the lack of infection possibly implies a higher concentration of the ghrelin hormone which would stimulate appetite in persons who would develop overweight, metabolic syndrome and diabetes. with the objective of determining the influence of this infection in diabetic people type 2, we carried out a descriptive study in the gastroenterology service of the territorial teaching hospital dr. mario mu?oz monroy, municipality of colon, during the period 2006-2008. we analysed variables like age, genre, and presence of the bacteria, among others, by mean of histological study and fast urease test, on samples of gastric mucosa obtained by endoscopy of the upper digestive tract. the results showed that 70 % of diabetic patients were not infected, and most of the patients with histological diagnosis of chronic gastritis were negative to helicobacter pylori (67,9 %). we concluded that the infection by helicobacter pylori, is less frequent in diabetic patients type 2.
Immunity and Helicobacter pylori  [cached]
Paul Harris
Medwave , 2011,
Abstract: The bacteria called Helicobacter pylori arrived to the American continent 12,000 years ago (1), reaching South America roughly 5,400-4,600 years AC according to research by Pelayo Correa, a Colombian pathologist who found Helicobacter in stool next to Chinchorro mummies in the North of Arica close to the Pacific Ocean. In 2005, Barry Marshall was awarded the Nobel Prize for his studies on Helicobacter pylori together with Robin Warren.
Frecuencia de Helicobacter pylori en diabéticos tipo 2 Frequency of Helicobacter pylori in diabetics Type 2  [cached]
Ania Hernández Ortega,Julio César Sánchez Cruz,Ibis Umpierrez García (2)
Revista M??dica Electr?3nica , 2010,
Abstract: El Helicobacter pylori es una bacteria relacionada con la enfermedad ulcerosa péptica, el adenocarcinoma, el linfoma MALT gástrico y otras afecciones extradigestivas, entre las que se encuentra la diabetes mellitus tipo 2, donde es posible que la ausencia de la infección conlleve a mayor concentración de la hormona grelina, quien estimularía el apetito en personas que desarrollarían sobre peso, síndrome metabólico y diabetes. Con el objetivo de determinar la frecuencia de esta infección en diabéticos tipo 2, se realizó un estudio descriptivo en el servicio de Gastroenterología, del Hospital Territorial Docente Dr. Mario Mu oz Monroy, del municipio de Colón, en el período 2006-2008. Se analizó edad, sexo, presencia de la bacteria, entre otras variables, por medio del estudio histológico y test de Ureasa rápido, a partir de muestras de mucosa gástrica obtenidas durante endoscopía del tracto digestivo superior. Resultó que el 70 % de los diabéticos no estaban infectados, y la mayoría de los pacientes con diagnóstico histológico de gastritis crónica resultaron Helicobacter pylori negativos (67,9 %), concluyéndose que la infección por Helicobacter pylori, en sentido general, es poco frecuente en los diabéticos tipo 2. Helicobacter pylori is a bacteria related with the peptic ulcerous disease, the adenocarcinoma, the gastric MALT lymphoma and other extradigestive diseases, diabetic mellitus Type 2 among them, where the lack of infection possibly implies a higher concentration of the ghrelin hormone which would stimulate appetite in persons who would develop overweight, metabolic syndrome and diabetes. With the objective of determining the influence of this infection in diabetic people type 2, we carried out a descriptive study in the Gastroenterology Service of the Territorial Teaching Hospital Dr. Mario Mu oz Monroy, municipality of Colon, during the period 2006-2008. We analysed variables like age, genre, and presence of the bacteria, among others, by mean of histological study and Fast Urease Test, on samples of gastric mucosa obtained by endoscopy of the Upper Digestive Tract. The results showed that 70 % of diabetic patients were not infected, and most of the patients with histological diagnosis of chronic gastritis were negative to Helicobacter pylori (67,9 %). We concluded that the infection by Helicobacter pylori, is less frequent in diabetic patients Type 2.
Behcet’s Disease and Helicobacter Pylori  [PDF]
Ramazan Dan??,Kadim Bayan,?erif Y?lmaz,Abdullah Alt?nta?
Dicle Medical Journal , 2004,
Abstract: The aim of this study is to investigate the relation between Beh et’s disease (BD) and Helicobacter pylori infection. The patients fulfilled the criteria of the International Study Group for Beh et’s disease. Helicobacter pylori infection was diagnosed by the rapid urease test and esophagogastroduodenoscopic examination performed to BD patients. Fourteen of the 22 patients with BD were Helicobacter pylori positive with rapid urease test. All patients with ophthalmic involvement were Helicobacter pylori positive with rapid urease test.
DIAGNOSIS OF HELICOBACTER PYLORI INFECTION  [cached]
Vladan N. Petrovi?
Acta Facultatis Medicae Naissensis , 2003,
Abstract: Helicobacter pylori is the most widen infection on the World. It is importrant factor in the genesis of ulcer disease, gastric carcinoma, gastric lymphoma, as a numerous extragastric disease. Diagnosis is made by invasive and non-invasive tests. Maastricht Consensus Report (2000) and First Consensus of Yugoslav Gastroenterologic Association recommend group of patients and methods for detection of Helicobacter pylori infection.
HISTORY OF HELICOBACTER PYLORI INFECTION  [cached]
Tomica Milosavljevi?,Aleksandar Nagorni
Acta Facultatis Medicae Naissensis , 2003,
Abstract: Helicobacter pylori was identified in 1979, but cultivated in Australia in 1982. Warren and Marshall were responsible for discovery. But, in the previous one hundred years, a lot of scientists tried to prove hipothesis about possible association between peptic ulcer disease and spiral microorganism. Numerous authors were objectivated H. pylori on some way. Consensus Conferences in Maastricht in 1996 and 2000 and First Consensus of Yugoslav Gastroenterologic Association gave us recommendation and guideline for diagnostics and treatment of H. pylori infection.
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