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Epitelioma calcificado de Malherbe  [cached]
Revista chilena de pediatría , 1952,
Epithelioma of Malherbe: new ultrasound patterns
Francesco M Solivetti, Fulvia Elia, Alessandra Drusco, Chiara Panetta, Ada Amantea, Aldo Di Carlo
Journal of Experimental & Clinical Cancer Research , 2010, DOI: 10.1186/1756-9966-29-42
Abstract: We retrieved 124 histologically Pilomatricoma cases: 28 patients with 32 lesions were preoperatively evaluated with ultrasound.22/32 have shown a solid formation, hypoechoic, with a sharp outline. Of these 22, 10 lesions were completely calcifying and 12 partially calcified. In 3/32 lesions with uncertain diagnosis, ultrasounds showed a complex/mixed pattern with pseudo-fluid areas and microspots. 7/32 lesions with US different diagnosis included 3 complex lesions, 2 cystic lesions and 2 solid nodular lesions.In addition to well-known ultrasound patterns (completely calcified and partially calcified) we identified three new, not yet described, patterns that constitute the 31% of the cases: complex, pseudocistyc and pseudotumoral.Calcifying Epithelioma of Malherbe - or Trichomatricoma, Pilomatricoma, Pilomatrixoma (PM) - is an uncommon tumour [1], with an incidence of 1/800-1000 cutaneous tumours and about 20 new reports per year [2,3], affecting predominantly women. It is more common at a young age, especially in the first two decades of life, with an onset below 10 years in 40% of cases [4,5]. Although multiple localizations have been described in literature [6,7], PM occurs as a solitary lesion on the face (47% of cases), neck [8] and upper trunk and can be associated to other diseases, e.g. Steinert's Myotonic Dystrophy and Gardner Syndrome [4,7,9,10].Recent studies have shown that recurrent activating mutations in the ss-catenina gene (CTNNB1), induce PM tumourigenesis through activation of the WNT signalling pathway [11,12]. Despite the benign biological behaviour of the majority of cases, the treatment is still surgical. However, in recent years, aggressive cases with local post-surgery recurrences or metastasis have been described [2,3,13,14], accounting for variable percentage rates in literature, with 6 cases out of 228 in the Forbis series [6]. According to some authors [13], local recurrences are related to tumour aggressiveness, while for others, these c
A Case Report of Calcifying Epithelioma of Malherbe (Pilomatrixoma) Mimicking Breast Carcinoma in Male Patient  [PDF]
Maria Marta Martins, Adrienne Pratti Lucarelli, José Mendes Aldrighi, Aline Forattini
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.35063

Pilomatricoma or calcifying epithelioma of Malherbe is a rare benign tumor of the skin and/or the subcutaneous tissue originating from the hair matrix. It is usually seen in children and adolescents, however a smaller second peak of onset is seen in the elderly. The head, neck, or upper extremities are the most common anatomical sites of pilomatricomas, being less frequently seen on the trunk and lower extremities, and very rarely have they been diagnosed in the breast. Its malignant counterpart, pilomatrix carcinoma, is rare and found more often in men. Due to its incapacity of regression, treatment consists of surgical excision. We present the case of a man with a pilomatrixoma of the breast, presenting as ACR BI-RADS 4, and we review the literature regarding pilomatrixomas.

Pilomatricoma: A dermal analog of calcifying odontogenic cyst  [cached]
Kaveri H,Punnya A
Indian Journal of Dental Research , 2008,
Abstract: Pilomatricoma, also known as "Calcifying Epithelioma of Malherbe" is an uncommon, benign, cutaneous tumor originating from the hair matrix. Most often, its precise preoperative diagnosis is not possible. Rarity of this lesion and its histological resemblance to the calcifying odontogenic cyst (the Gorlin′s cyst) make it relevant, both to the maxillofacial surgeons and the pathologists. Here, we describe a case of pilomatricoma of the periorbital region in a young Indian female patient. We believe that its inclusion is essential in the differential diagnosis of hard masses of the maxillofacial and paraoral regions.
Calcifying Epithelioma of Malherbe-A Diagnostic Challenge on FNAC  [PDF]
Kuldeep Singh, Satish Sharma,M.Barbotra,V.K Dubey
JK Science : Journal of Medical Education & Research , 2002,
Abstract: Pilomatrixoma or calcifYing epithelioma ofMalherbe is one ofbenign adenexal tumors ofthe skin.!toccurs in all the age groups with common locations in the head and neck region. Fine needle aspirationcytolog) has a challenge in the diagnosis of these tumors.We report a similar case of calcifyingepithelioma.
Malignant pilomatricoma
Kapadia R,Chatura K
Indian Journal of Dermatology, Venereology and Leprology , 1990,
Abstract: A 26 year old man developed a locally recurrent tumour on the back. The lesion showed histopathological features of pilomatricoma but differed from that lesion by presence of cytological atypia, squamous differentiation, numerous mitoses and infiltration into underlying structures.
Basal Cell Epithelioma Eroding Into The Eye
Somasundaram V,Jayaraaman A M
Indian Journal of Dermatology , 2004,
Abstract: A case of basal cell epitelioma involving and eroding into the right eye with classical clinical and histopathological features has been reported.
Calcifying Tumor of Malherbe  [cached]
Dr.Bharti Padmakar Baviskar,Dr. Ravindra Karle,Dr. Shubhangi Prashant Nigwekar,DR. SOMEN MISRA
International Journal of Biomedical and Advance Research , 2013, DOI: 10.7439/ijbar.v4i3.321
Abstract: ABSTRACT Tumours of the eyelid are not very common. Frequently we come across squamous cell carcinoma. We are reporting a rare case of calcifying epithelioma of eye. The usual presenting region is the hair bearing areas of body and upper extremity. A 15 years old male presented with swelling over upper lid. Clinically diagnosed as molluscum contagiosum. Surgical excision was carried out. Histopathology confirmed it as calcifying epithelioma of the eye. Epithelioma situated over the eyelid is very rare.
Multiple Calcifying Epitheliomas of Malherbe’s of Axilla: A Case Report of Rare Variety  [PDF]
Mushtaq Chalkoo, Shahnawaz Ahangar, Naseer Awan, Mujahid Ahmad Mir, Aarif Bashir, Nida Shafiq
Surgical Science (SS) , 2014, DOI: 10.4236/ss.2014.56042

Pilomatrixoma, a rare benign tumour of sebaceous gland is commonly known as calcifying epithelioma of Malherbe or Tricholemmal cyst. We came across even the rarest form of this benign tumour of skin. Our case report was interestingly detected at a higher age group, unusual site of the body, multiple in nature following postoperative incision drainage of abscess in left axilla.

Cutaneous ameobiasis masquerading as epithelioma  [cached]
Chandrasekhar H,Shashikala P,Kumar Prakash,Basavaraj P
Indian Journal of Dermatology, Venereology and Leprology , 1993,
Abstract: A case of cutaneous amoebiasis, clinically diagnosed as epithelioma, presenting as an ulcer in the perianal region, in a 30-year old male is reported. The patient was successfully treated with metronidazole.
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