oalib
Search Results: 1 - 10 of 100 matches for " "
All listed articles are free for downloading (OA Articles)
Page 1 /100
Display every page Item
A Comparative Evaluation of Phytochemical Fingerprints of Asteracantha longifolia Nees. Using HPTLC  [PDF]
S. Sunita,S. Abhishek
Asian Journal of Plant Sciences , 2008,
Abstract: Chromatographic techniques can be used to document phytochemical fingerprints and quantitate chemical markers to identify morphological and geographical variations in the herbal raw material. In this context, phytochemical profile of Asteracantha longifolia Nees. (syn. Hygrophila spinosa T. Anders.; Hygrophila auriculata [K. Schum.] Heine), an important medicinal herb, was developed using HPTLC technique and was successfully used for evaluating regional and morphological variations. The HPTLC fingerprints were also used for the quantitation of two bioactive markers β-sitosterol and Lupeol in the plant powder. These phytochemical markers were also evaluated from different parts of the plant and from the whole plant collected from different geographical regions. Maximum content of Lupeol was found to be in roots (0.25%), while maximum content of β-sitosterol was found to be in the leaves (0.069%) of Asteracantha longifolia Nees.
Asteracantha longifolia (L.) Nees, Acanthaceae: chemistry, traditional, medicinal uses and its pharmacological activities - a review
Chauhan, Nagendra Singh;Dixit, V. K.;
Revista Brasileira de Farmacognosia , 2010, DOI: 10.1590/S0102-695X2010005000022
Abstract: asteracantha longifolia (l.) nees, acanthaceae, is a source of the ayurvedic drug, 'kokilaaksha' and the unani drug, talimakhana. the seeds are acrid, bitter, aphrodisiac, tonic, sedative, used for diseases of the blood. the plant is known to possess antitumor, hypoglycemic, aphrodisiac, antibacterial, free radical scavenging and lipid peroxidation, hepatoprotective and haematopoietic activity. it contains lupeol, stigmasterol, butelin, fatty acids, and alkaloids. the present review article is focused on phytochemical, pharmacological and other important aspects of talimakhana.
Asteracantha longifolia (L.) Nees, Acanthaceae: chemistry, traditional, medicinal uses and its pharmacological activities - a review Asteracantha longifolia (L.) Nees, Acanthaceae: química, usos tradicionais e medicinais e suas atividades farmacológicas - uma revis o  [cached]
Nagendra Singh Chauhan,V. K. Dixit
Revista Brasileira de Farmacognosia , 2010,
Abstract: Asteracantha longifolia (L.) Nees, Acanthaceae, is a source of the ayurvedic drug, 'Kokilaaksha' and the Unani drug, Talimakhana. The seeds are acrid, bitter, aphrodisiac, tonic, sedative, used for diseases of the blood. The plant is known to possess antitumor, hypoglycemic, aphrodisiac, antibacterial, free radical scavenging and lipid peroxidation, hepatoprotective and haematopoietic activity. It contains lupeol, stigmasterol, butelin, fatty acids, and alkaloids. The present review article is focused on phytochemical, pharmacological and other important aspects of Talimakhana. Asteracantha longifolia (L.) Nees, Acanthaceae, é a fonte do medicamento ayurvédico "Kokilaaksha", e da droga Unani, Talimakhana. As sementes têm de sabor acre e amargas, s o afrodisíacas, t nicas, calmantes, e usadas para doen as do sangue. A planta é conhecida por possuir propriedades antitumorais, hipoglicêmica, afrodisíaca, anti-bacteriana, na elimina o de radicais livres e peroxida o lipídica, atividade hepatoprotetora e hematopoiéticas. Ele contém lupeol, estigmasterol, butelina, ácidos graxos e alcaloides. Este trabalho apresenta estudos químicos, farmacológicos e outros aspectos importantes da Talimakhana.
1. Antidiabetic efficacy of leaf extracts of Asteracantha longifolia (Linn.) Nees. on alloxan induced diabetics in male albino wistar rats
M. Muthulingam
International Journal of Pharmaceutical and Biomedical Research (IJPBR) , 2010,
Abstract: The present study was undertaken to investigate the effect of aqueous extract of Asteracantha longifolia on alloxan induced diabetics in male albino Wistar rats. Alloxan induced diabetic rats were treated with aqueous extract of Asteracantha longifolia at the doses of 100, 200 and 400 mg/kg, p.o. and its influence on glucose level, insulin, hemoglobin, glycosylated hemoglobin, alanine transaminase, aspartate transaminase, serum total cholesterol, levels of pancreas enzymatic and non-enzymatic antioxidant enzymes (superoxide dismutase, catalase and reduced glutathione) were observed. Histological observation of pancreas also studied. Oral administration of aqueous extract of Asteracantha longifolia at the dose of 100, 200 and 400 mg/kg, p.o. to alloxan treated rats showed significantly decrease in plasma glucose, glycosylated hemoglobin, alanine transaminase, aspartate transaminase, serum total cholesterol, where as plasma insulin, hemoglobin, levels of pancreas enzymatic and non-enzymatic antioxidant enzymes (superoxide dismutase, catalase and reduced glutathione) were significantly increased. Histopathological observation of pancreas reverses the trends towards normalcy. Hence, it can be concluded that Asteracantha longifolia leaf extracts may be prove to be effective in the treatment of diabetes mellitus owing to its ability to increase insulin secretion and enhance the antioxidant activity.
Haematopoietic activity of Asteracantha longifolia on cyclophosphamide-induced bone marrow suppression  [cached]
Pawar R,Jain A,Kashaw S,Singhai A
Indian Journal of Pharmaceutical Sciences , 2006,
Abstract: Chloroform extract of the leaves of Asteracantha longifolia at different doses (250 and 500 mg/kg body weight) was examined on anaemic albino rat for certain haematological parameters like erythrocyte count, leukocyte count, and haemoglobin count. Chloroform extract was found to significantly (b,b1,b2,b3P < 0.05) improve erythrocyte and haemoglobin count on the 22nd day (d) after 7 d of continuous cyclophosphamide (3 mg/kg body weight) treatment. Treatment with chloroform extract along with cyclophosphamide was found to significantly ( P < 0.001) increase the bone marrow cellularity (11.5x106) as compared to cyclophosphamide alone treated group (6.2x106). Administration of extract increased the number of a-esterase positive cells (1062/4000) in the bone marrow of cyclophosphamide-treated animals, compared to the cyclophosphamide alone treated group (650/4000). The major activity of A. longifolia may be stimulation of stem cell proliferation. The observations that A. longifolia could reduce the cyclophosphamide-induced toxicity may indicate its usefulness in cancer therapy.
Toxicity evaluation of Ethanolic Extract of Astercantha longifolia Seeds
Rajina PV,Shini Dominic
Hygeia : Journal for Drugs and Medicines , 2013,
Abstract: Plan: To verify the toxiceffects of the ethanolic extract of Asteracanthalongifolia seeds after single and repeated administrationPrologue: Usually traditional medicines arenot subjected to routine toxicological studies. As a result many adverseeffects caused by the chronic use of herbal medicines may be wrongly attributedto certain acute or chronic diseases Though Asteracantha longifolia seeds aretraditionally used for the treatment of sexual debility, premature ejaculationand oligospermia, there is no evidenceabout its toxicity.Methodology: Acutetoxicity of the plant extract was carried out as per the OECD guideline 425. Sub acutetoxicity study of 28 day duration was carried out in three different doses of 100 mg/kg, 250 mg/kg and500 mg/kg.orally.Outcome: No significant variation in hematologic andbiochemical parameters and in relative organ weight with doses of 100, 250 and500mg/kg body weight. Histopathology showed the presence of slight necrosis inseminiferous tubules at dose of 500mg/kg. It may be concluded that thealcoholic extract of Asteracantha longifoliaseeds is safe for oral administration at low and moderate doses while high dose(500mg/kg) is not absolutely free from toxic effects.Key words: Asteracanthalongifolia, acute toxicity, Sub acutetoxicity.
A STUDY OF ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACTS AND AQUEOUS EXTRACTS OF Leucas longifolia (Doron) LEAVES AGAINST Eschreiashia coli
Amar Jyoti Das
International Research Journal of Pharmacy , 2012,
Abstract: Leucas longifolia Benth also known as Doron (Assam) is an important herb frequently used in various folk remedies of Assam. The present study was designed to evaluate the antibacterial activity of aqueous extract and ethanol leaf extract of Leucas longifolia against disease causing Eschreiashia coli. Aqueous extract showed strong and superior antibacterial activity against Eschreiashia coli as compared to ethanol extract. These results were compared with standard antibiotic Norfloxacin. But the aqueous extract showed higher activity than the given standard antibiotic. These findings support the traditional use of the plant in the treatment of different infections in the area of medical science.
AN OVERVIEW ON ANDROGRAPHIS PANICULATA (BURM. F.) NEES
Ghosh Kumar Benoy,Datta Kumar Animesh,Mandal Aninda,Dubey Kumari Priyanka
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: Andrographis paniculata (Burm. F.) Nees (Family: Acanthaceae) commonly known as Kalmegh (King of Bitters) is an important plant species in Ayurvedic medicine (prominent in 26 Ayurvedic formulations). An overview is conducted in the species considering all essential aspects namely, therapeutic uses, synonyms, common names, distribution, habitat, soil condition, cultivation, harvest, post harvest and storage, plant description, reproductive biology, cytological aspects, cytogenetical study, molecular genetics, extraction and detection of phytochemicals, assay, phytochemistry, insecticidal activity, clinical trials, contraindications and drug interactions, clinical implications, regulatory mechanism, in vitro studies and mutational studies to provide unabridged repository of references to researchers for its effective biological utilization.
Phytochemical Study of Swertia Longifolia
H Hajimehdipoor,M.G Dijoux-Franca,A.M Mariotte,Y Amanzadeh
DARU : Journal of Pharmaceutical Sciences , 2008,
Abstract: Background: Swertia spp. (Gentianaceae) grow widely in eastern and southern Asian countries such as Japan, China and India and are used as traditional remedy for gastrointestinal complains because of their bitter principles. Several studies have been carried out on hypoglycemic, hepatoprotective, mono amino oxidase inhibitory and antidepressant effects of these plants and it has been shown that xanthones and iridoids are responsible for their activities. Purpose of the study: In order to gain better knowledge of endemic plants of Flora Iranica, Swertia longifolia Boiss. growing in the northern parts of Iran, was subjected to phytochemical studies. Methods: Dried and milled aerial parts of the plant were extracted with petroleum ether and ethanol of which results of petroleum ether extract has been reported previously. For purification of ethanol extract, it was acidified with acetic acid and subsequently extracted with chloroform and then with n-butanol. The n-butanol extract was analyzed using different chromatographic methods and the structures of the isolated components were established by means of spectroscopic techniques. Results: Four components including an iridoid glycoside (loganic acid), a secoiridoid glycoside (gentiopicroside), a secoiridoid dilactone (gentiolactone) and a nucleoside (uridine) were isolated from n-butanol extract of the plant. Major conclusion: Similar to other species of Swertia, iridoid and secoiridoid glycosides could be considered as major constituents of Swertia longifolia Boiss.
Constituents of Encyclia longifolia Schltr. (Orchidaceae)
Bhattacharyya, Jnanabrata;Nishonov, Abdumalik A.;Felix, Leonardo Pessoa;Pires, Maria F.O.;Majetich, George M.;
Revista Brasileira de Farmacognosia , 2006, DOI: 10.1590/S0102-695X2006000100006
Abstract: a detailed chemical analysis of the non-volatile secondary metabolites of encyclia longifolia schltr. syn. epidendrum longifolium barb. rodr. was carried out in an attempt to lend a chemotaxonomic support for the recent separation of the genus encyclia into encyclia hook and prosthechea knowles & westc.
Page 1 /100
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.