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Two Legionnaires' disease cases associated with industrial waste water treatment plants: a case report
Jaana Kusnetsov, Liisa-Kaarina Neuvonen, Timo Korpio, S?ren A Uldum, Silja Mentula, Tuula Putus, Nhu Nguyen Tran Minh, Kari-Pekka Martimo
BMC Infectious Diseases , 2010, DOI: 10.1186/1471-2334-10-343
Abstract: We report two cases of severe pneumonia in employees working at two separate mills in Finland in 2006. Legionella serological and urinary antigen tests were used to diagnose Legionnaires' disease in the symptomatic employees, who had worked at, or close to, waste water treatment plants. Since the findings indicated a Legionella infection, the waste water and home water systems were studied in more detail. The antibody response and Legionella urinary antigen finding of Case A indicated that the infection had been caused by Legionella pneumophila serogroup 1. Case A had been exposed to legionellae while installing a pump into a post-clarification basin at the waste water treatment plant of mill A. Both the water and sludge in the basin contained high concentrations of Legionella pneumophila serogroup 1, in addition to serogroups 3 and 13. Case B was working 200 meters downwind from a waste water treatment plant, which had an active sludge basin and cooling towers. The antibody response indicated that his disease was due to Legionella pneumophila serogroup 2. The cooling tower was the only site at the waste water treatment plant yielding that serogroup, though water in the active sludge basin yielded abundant growth of Legionella pneumophila serogroup 5 and Legionella rubrilucens. Both workers recovered from the disease.These are the first reported cases of Legionnaires' disease in Finland associated with industrial waste water systems.From 1995 until 2007, the number of reported Legionnaires' disease (LD) cases in Finland has varied from 10 up to 31 per year, with an annual incidence of 2-6 cases per million [1]. The reporting of LD and Legionella-positive laboratory results has been mandatory for both clinicians and clinical laboratories since 1995. The incidence rate in Finland is much lower compared to the mean incidence rate of LD in European countries, which has been 11 cases per million in 2007 and 2008 [2].Previous Finnish Legionella survey studies revealed tha
Reflections on the value concept in accounting  [cached]
P. Buys
Koers : Bulletin for Christian Scholarship , 2009, DOI: 10.4102/koers.v74i3.135
Abstract: The recent meltdown in global finances and the reasons for it may make people doubtful about the stewardship function of accounting. In the global financial markets, there is a great fascination with the reality that accounting values intend to reflect. However, what many people considered valuable is now suddenly of no value. The question can therefore be asked what is meant by the value concept as a foundation to modern-day accountancy. “Value” is a concept that is open to different interpretations, based on the needs, perspectives and personal values of the interpreter. This article aims to reflect on the value concept from an accounting perspective in analysing the fundamental quali-tative perspectives and how these perspectives might affect the quantitative value measurements, as reported in the financial statements. From a quantitative perspective, accounttancy aims to measure and report the monetary values of items. However, there is a move towards a mixed valuation model with many financial statements, including both historical cost and value-based accounting information. The article concludes that this questionable development opens up many additional and subjective interpretations of accounting value measurement and reporting. Both valuation measurement methods have merit when considered in the overall purpose of accounting information. However, subjective value-based mea-surements may cast a shadow of doubt on the reliability and comparability requirements of accounting value information.
Screening of Natural Antioxidants from Traditional Chinese Medicinal Plants Associated with Treatment of Rheumatic Disease  [PDF]
Ren-You Gan,Lei Kuang,Xiang-Rong Xu,Yuan Zhang,En-Qin Xia,Feng-Lin Song,Hua-Bin Li
Molecules , 2010, DOI: 10.3390/molecules15095988
Abstract: In order to find new sources of natural antioxidants, the antioxidant capacities of 50 medicinal plants associated with treatment of rheumatic diseases were systemically evaluated using the ferric-reducing antioxidant power (FRAP) and Trolox equivalent antioxidant capacity (TEAC) assays, and their total phenolic contents were measured by the Folin–Ciocalteu method. Their antioxidant activities of some of these plants were analyzed for the first time. The FRAP and TEAC assay results suggested that the antioxidant compounds in these plants possessed free radicals scavenging activity and oxidant reducing power. A positive linear correlation between antioxidant capacities and total phenolic contents implied that phenolic compounds in these plants could be the main components contributing to the observed activities. The results showed that Geranium wilfordii, Loranthus parasiticus, Polygonum aviculare, Pyrrosia sheaeri, Sinomenium acutum and Tripterygium wilfordii possessed the highest antioxidant capacities and total phenolic content among 50 plants tested, and could be rich potential sources of natural antioxidants.
Induction of Systematic Resistance in Soybean Plants against Fusarium Wilt Disease by Seed Treatment with Benzothiadiazole and Humic Acid  [cached]
Montaser Fawzy ABDEL-MONAIM,Mamdoh Ewis ISMAIL,Kadry Mohamed MORSY
Notulae Scientia Biologicae , 2011,
Abstract: The ability of benzothiadiazole (BTH), humic acid (HA) and their combination when used as seed soaking to induce systemic resistance against a pathogenic strain of Fusarium oxysporum was examined in four soybean cultivars under greenhouse conditions. Both inducers and their combination were able to protect soybean plants against damping-off and wilt diseases compared with check treatment. These results were confirmed under field conditions in two different locations i. e Minia and New Valley governorates. The tested treatments significantly reduced damping-off and wilt diseases and increased growth parameters, except number of branches plant-1, and seed yield. Application of BTH (0.25) + HA (4 g/l) was the most potent in this respect treatment. Soybean seed soaking in BTH+ HA recorded the highest activities of the testes of oxidative enzymes followed by BTH in the four soybean cultivars. Whereas, HA treatment was recorded the lowest increased of these oxidative enzymes. Also, similar results were obtained in case of total phenol but HA increased the total phenol more than BTH in all tested cultivars.
Reflexiones en torno a los problemas éticos y bioéticos en el tratamiento del paciente en fase terminal Reflections about the ethical and bioethical problems in treatment presenting with a terminal disease
Marilyn Sánchez Mu?iz,Camilo González Pérez
Revista Cubana de Medicina General Integral , 2009,
Abstract: Se realizó una revisión bibliográfica sobre aspectos éticos y bioéticos en el tratamiento del paciente en estado terminal. Es un derecho de todos los ciudadanos que se les atienda y proteja su salud, teniendo como referencia el marco legal y el concepto actual de salud, en el que cobran vigencia los 3 principios fundamentales que forman el triángulo bioético: autonomía, justicia y beneficencia. La actuación ética con estos pacientes que reciben cuidados paliativos no difiere de los principios rectores de cualquier otro acto relacionado con la atención médica,ya que toda acción debe estar dirigida al beneficio del ser humano sin provocar da os. Existe considerable confusión y controversia en cuanto a la ética del cuidado terminal, particularmente en las áreas más polémicas de resucitación, en el inicio y cese de tratamientos, la alimentación y la eutanasia. El enfermo terminal tiene derecho a vivir hasta su máximo potencial físico, emocional, espiritual, vocacional y social, compatible con el estado resultante de la progresión de la enfermedad. Estos son los aspectos que se tratan en este trabajo. A bibliographic review was conducted about ethical and bioethical features in treatment of patient presenting a terminal disease. It is a right of all citizens the care and protection of his health within the legal framework and the current concept of health, with validity of the three fundamental principles included in bioethical triangle: autonomy, justice and charity. Ethical conduct with these patients receiving palliative cares not differs of the governing principles of any act related to medical care, since all action must to be directed to benefit of human being without cause damages. There is much confusion and controversy as regards the terminal care ethics, particularly in the more controversial areas of resuscitation, at onset and end of treatments, feeding and euthanasia. Patient presenting with a terminal disease has the right of live until its maximal physical emotional, spiritual, vocational and social potential compatible with the resulting state of disease progression. These are the features approached in present paper.
Genetic Engineering for Viral Disease Management in Plants  [cached]
Shabir Hussain WANI,Gulzar S. SANGHERA
Notulae Scientia Biologicae , 2010,
Abstract: Viral diseases are a major threat to world agriculture and breeding resistant varieties against these viruses is one of the major challenge faced by plant virologists and biotechnologists. The development of the concept of pathogen derived resistance gave rise to strategies ranging from coat protein based interference of virus propagation to RNA mediated virus gene silencing. Much progress has been achieved in protecting plants against these RNA and DNA viruses. In this review, the most recent transgene based approaches for viral disease management in plants will be discussed.
Competence and teaching skills: reflections on the concept and assessment  [PDF]
Isabel Guzmán Ibarra,Rigoberto Marín Uribe
Revista Electronica Interuniversitaria de Formación del Profesorado , 2011,
Abstract: This article discusses some concepts of competence, to identify their common elements that can be transferred to educational practices on competition. The intention is to establish levels of consistency among the components of the concept with educational practices and competitions. On this basis, we discuss some strategies for teaching skills to identify and propose strategies and tools that focus on authentic assessment to evaluate teaching skills.
Gaucher Disease and Cancer: Concept and Controversy  [PDF]
Francis Y. M. Choy,Tessa N. Campbell
International Journal of Cell Biology , 2011, DOI: 10.1155/2011/150450
Abstract: Gaucher disease is an inherited disorder caused by a deficiency in the lysosomal hydrolase glucocerebrosidase. There is a wide spectrum of clinical presentations, with the most common features being hepatosplenomegaly, skeletal disease, and cytopenia. Gaucher disease has been classified into three broad phenotypes based upon the presence or absence of neurological involvement: Type 1 (nonneuronopathic), Type 2 (acute neuronopathic), and Type 3 (subacute neuronopathic). The two main treatment options include enzyme replacement therapy and substrate reduction therapy. Recently, discussion has escalated around the association of Gaucher disease and cancer, with conflicting reports as to whether Gaucher patients have an increased risk of malignancy. In this review, we present both the concept and controversy surrounding the association of Gaucher disease with cancer. 1. Introduction Gaucher disease is a panethnic autosomal recessive disorder characterized by a heterogeneous set of signs and symptoms caused by the defective hydrolysis of glucocerebroside. A deficiency in the enzyme glucocerebrosidase (glucosylceramidase, acid β-glucosidase) leads to the accumulation of glucocerebroside in the spleen, liver, and bone marrow. The resultant hepatosplenomegaly, haematological changes, and orthopaedic complications are the predominant symptoms [1]. Gaucher disease has been classified into three broad phenotypes. Type 1, the most common form, has no central nervous system involvement. Conversely, patients with Type 2 (acute neuronopathic disease) suffer from an aggressive form that leads to death perinatally or within the first few years of life. In Type 3 (subacute neuronopathic disease), patients show neurodegenerative symptoms but are able to survive through childhood to adulthood [2, 3]. The glucocerebrosidase gene is found on chromosome 1q21-22, consisting of 11 exons encoding a 497-amino-acid protein. A highly homologous pseudogene, located 16?kb downstream, complicates mutation analysis in this region. To date, nearly 300 mutations have been identified in Gaucher’s patients, including point mutations, deletions, insertions, splice site mutations, frame-shift mutations, and recombinant alleles [4–6]. Gaucher disease is the most common lysosomal storage disorder and the first to be successfully treated by enzyme replacement therapy [7]. In 1991, alglucerase (Ceredase, Genzyme Inc.), the placental derivative of glucocerebrosidase was FDA-approved. In 1994, the human recombinant-form imiglucerase (Cerezyme, Genzyme Inc.) received FDA approval. Alglucerase is
Deconstructing the Therapeutic Alliance: Reflections on the Underlying Dimensions of the Concept
Krause,Mariane; Altimir,Carolina; Horvath,Adam;
Clínica y Salud , 2011,
Abstract: the concept of the alliance has received increasing attention from both clinicians and researchers over the past thirty years. yet it remains only vaguely defined, and its role and effect in therapy continues to be controversial. the goal of this paper is to clarify the meaning of the concept as it is perceived by clients and therapists, and to compare and contrast these perceptions to the notion of the alliance as it is de-facto implemented in research through the most frequently used alliance measures. our results indicate that clients and therapists pay attention to different aspects of the relationship when they assess the quality of the alliance. the most frequently used measures share some important features but also exhibit significant differences. some alliance measures attempt to accommodate the differences in the clients′ and therapists′ points of view but others ignore them. in general, these popular measures do not appear to be closely matched to the unique client/therapist perspectives. the impact of the substantial variations between measures and the absence of a clear distinction between the differing perspectives of clients and therapists is discussed.
Youth Mobilisation as Social Navigation. Reflections on the concept of dubriagem  [cached]
Henrik Vigh
Cadernos de Estudos Africanos , 2011, DOI: 10.4000/cea.110
Abstract: This article sheds light on the mobilisation of young people into conflict. It argues that warfare constitutes a terrain of possibility for urban youth in Guinea-Bissau, and shows how they navigate war as an event by tactically manoeuvring within the social ties and options that arise in such situations. Building on the Guinean Creole term of dubriagem, the article proposes the concept of social navigation as an analytical optic able to shed light on praxis in unstable environments. The concept of social navigation makes it possible to focus on the way we move within changing social environments. It is processuality squared, illuminating motion within motion. The article thus advocates an analysis of praxis that takes its point of departure in a Batesonian and intermorphological understanding of action in order to further our understanding of the acts of youth in conflict. Este artigo foca a mobiliza o para o conflito dos jovens, alegando que a guerra constitui um terreno de possibilidades para a juventude urbana na Guiné-Bissau e mostrando como estes mesmos jovens navegam através da guerra através de op es tácticas e manobrando os seus la os sociais. Baseando-se no termo crioulo guineense dubriagem, o artigo prop e o conceito de navega o social enquanto uma perspectiva de análise esclarecedora da práxis em ambientes instáveis. Este conceito foca as formas de actua o em ambientes de mudan a social, enquadrando o processo de movimento. O artigo defende uma análise da práxis partindo de uma interpreta o Batesoniana e intermorfológica da ac o para aprofundar a compreens o dos actos dos jovens em situa es de conflito.
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