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Nasal Septum Perforation due to Methamphetamine abuse
Mehdi Bakhshaee,Ehsan Khadivi,Masoud Naseri Sadr,Fereshteh Esmatinia
Iranian Journal of Otorhinolaryngology , 2012,
Abstract: Introduction: Spontaneous Perforation of the nasal septum is an uncommon condition. Nasal inhalation of substances such as cocaine has long been linked to this Perforation. Case Report: This report describes the case of a 46-year-old woman who was addicted to methamphetamine and who presented with perforation of the nasal septum.This is the first reported case of nasal septal necrosis linked to nasal inhalation of methamphetamine. Conclusions: Patient history and assurance regardingillegal drug consumption and abuse is a key point for fast and accurate diagnosis. The pathophysiology of drug-induced sinunasal disease and a review of the literature are also presented.
Septum nasal perforation: treatments and literature' review  [cached]
Martinez Neto, Eulógio Emílio,Dolci, Luiz Eduardo Lutaif,Murta, Alexandre Antonio,Zanini, Fábio Duro
International Archives of Otorhinolaryngology , 2010,
Abstract: Introduction: The present study consists in a bibliographical' review concerning the articles related to the different manifestations and forms of the septum nasal perforation, with a main emphasis in the description of its techniques of surgical correction. As the etiology, that is fundamentally iatrogenic, accordingly surgical trauma. Other causes include exhibition to chemical industrial reagents, cocaine use, intranasal steroidal therapeutic, neoplasia and, infectious conditions. There is a few data concerning the prevalence of septum perforation in the general population. The decision making about surgical correction or medical treatment depend on the anatomic characteristics and of the pathogenesis of the septal perforation.
Nasal septum perforation in patient with pyoderma gangrenosum  [cached]
Maia, Camilla Bezerra da Cruz,Felix, Felippe,Paes, Vania,Azevedo, Julia Alves de
International Archives of Otorhinolaryngology , 2012,
Abstract: Introduction: The cocaine is obtained from the leaves of the coca (Erythroxylon coca). It can be used in many ways, but the most common is the drug inhalation. The Cocaine also causes vasoconstriction at nasal mucous membrane and its chronic use can cause necrosis and nasal septum perforation. Pyoderma gangrenosum is an uncommon idiopathic disease characterized by ulcerations, usually observed on the legs. Its diagnosis is most common an exclusion of others diseases. So far, there is no specific treatment based on evidence by randomized controlled trials. Objective: Describe the rare association between Pyoderma gangrenosum and cocaine. Case Report: E. A., 27-year-old woman with destruction of nasal septum and palate who has been using a big amount of cocaine, been necessary note the difference from which disease cause de damage. Final Comments: Also there are only three cases of Pyoderma gangrenosum complicated with nasal septum perforation in cocaine users.
Eosinophilic Angiocentric Fibrosis of the Nasal Septum  [PDF]
Yunchuan Li,Honggang Liu,Demin Han,Hongrui Zang,Tong Wang,Bin Hu
Case Reports in Otolaryngology , 2013, DOI: 10.1155/2013/267285
Abstract: Background. Eosinophilic angiocentric fibrosis (EAF) is a rare benign condition of unknown aetiology that causes stenosis of the upper respiratory tract. It is most commonly found at the nasal septum and sinus mucosa causing mucosal thickening and nasal obstructive symptoms. The diagnosis is mainly based on characteristic histologic findings. Case Report. A 27-year-old young woman presented with a slow growing mass at her anterior nasal septum for over eight years. She complained of persistent nasal obstruction, epistaxis, sometimes diffused facial pain, and chronic headache. 3 years ago, the tumor was partially resected for ventilation and a nasal septum perforation was left. Imaging findings indicated soft-tissue thickening of the anterior part of septum and adjacent lateral nasal walls. Pathological examination showed numerous inflammatory cells infiltrates containing eosinophils, fibroinflammatory lesion with a whorled appearance fibrosis which typically surrounded vessels. A diagnosis of eosinophilic angiocentric fibrosis was made. All laboratory tests were unremarkable. Skin prick test was positive. The tumor-like lesion was totally resected. Conclusions. EAF is a rare benign and progressive disorder causing destruction. Combined with radiological imaging of EAF historical findings contribute to the diagnosis. It is important to prevent tumor from recurrence by total resection of the lesion. 1. Introduction Eosinophilic angiocentric fibrosis (EAF) is a rare, benign condition of unknown aetiology which may cause local tissue progressive destruction [1]. It mainly involves the sinonasal tract and is especially common at the nasal septum. EAF typically presents in young to middle-aged females. Most of the patients complain of progressive sinonasal obstructive with a tumor-like lesion. The etiology of EAF is unknown, and the diagnosis is mainly based on histologic findings. The histologic features include perivascular inflammatory cell infiltration (mainly eosinophils). The eosinophils infiltration is gradually replaced by the progressive fibrosis lesion with “onion-skin” pattern around small blood vessels [1–6]. It was first described by Holmes and Panje in 1983 who reported a case of so-called ‘‘intranasal granuloma faciale” [7]. After two years, Roberts and McCann reported two female patients with an unusual stenosing lesion involving the upper respiratory. They gave a descriptive diagnosis according to the histologic findings: eosinophilic angiocentric fibrosis [8]. Until now, 51 patients diagnosed with EAF have been reported in the English
Perforation of the Nasal Septum and Nasal Ulcers  [PDF]
Maria Pilar Martín-Fortea, Isabel Sanjoaquín-Conde, Santiago Letona-Carbajo, Maria José Crusells-Canales, Julián Cuesta-Mu?oz, Juan Antonio Amiguet-García
World Journal of AIDS (WJA) , 2011, DOI: 10.4236/wja.2011.12005
Abstract: A case about a HIV woman with nasal ulcers is described in this paper. In every inmunodepressed patient who has mu-cosal or cutaneous ulcers, infection by leishmanial parasites needs to be ruled out, especially when ulcers have not re-gression with usual treatments. The Leishmanial nasal disease usually shows swelling and mucosal ulcers, that may progress to necrosis. Delaying in appropriate therapy might cause irreversible damage.
Nasal septal perforation 1981–2005: Changes in etiology, gender and size
Liv D?sen, Rolf Haye
BMC Ear, Nose and Throat Disorders , 2007, DOI: 10.1186/1472-6815-7-1
Abstract: This is an open, prospective clinical study of patients seen at our hospital from 1981 to 2005. The clinical data of size, gender and etiology have been recorded consecutively.One hundred and ninety seven patients (100 male, 97 female) were evaluated. Between 1981 and 1995 nasal septal perforation was caused by surgery in 40 of 102 (39.2 %). In the period 1995 to and inclusive of 2005 this percentage decreased as septal resection has been replaced by septo/septorhinoplasty. The latter was the cause for septal perforation in 14.7% in the last period. Nasal steroid and decongestive sprays have emerged as an important cause (28.4 %) during the last ten years particularly in females. In the first period 44 (43.1 %) and in the last 53 (55.7 %) patients were females. There was a noticeable reduction in the number of septal perforations 15 mm or larger in the last period.Nasal steroid and decongestive sprays are now important causes for septal perforation. Information about this complication should be given with an advice to immediately report increasing and bothersome crusting and bleeding. Warning of the simultaneous use of nasal steroid and decongestive sprays should be addressed particularly to females. All patients with symptoms of septal perforation should promptly be referred to otolaryngologists for treatment.The treatment of nasal septal perforation (SP) is symptomatic (local application of ointments), prosthetic, or surgical. Surgery may be curative but the results are not always satisfactory as evidenced by the many different operative procedures that have been proposed [1-7]. Prevention of SP should be an important goal. The purpose of this study was to examine our clinical data to look for possible changes in the pattern of etiology in order to identify causes that may be suitable for preventive measures. We have also registered the size of the SP in order to establish whether the size would indicate that the patients should have been referred sooner.We have r
The Coexistence of Pulmonary Artery Aneurysm and Nasal Septal Perforation
Trakya Universitesi Tip Fakultesi Dergisi , 2007,
Abstract: A 45-year-old male patient presented with a one week history of pleuritic chest pain, cough, and breathlessness. He had a diagnosis of chronic obstructive pulmonary disease for eight years. His initial chest radiograph revealed left lower zone infiltration. A cavitary lesion developed despite treatment with two antibiotics. Thorax computerized tomography scan revealed bilateral cavitary lesions and aneurysms in the main pulmonary arteries. Later, the patient reported recurrent oral ulcers, but rhinoscopy demonstrated nasal septal perforation. A definitive diagnosis could not be established despite biopsies from the nasal septum and buccal mucosa.
Etiologia e tratamento de desvios de septo nasal em recém-nascidos: revis o da literatura = Etiology and treatment of nasal septum deviation in newborn infants: Literature review  [cached]
Carpes, Luthiana Frick,Fiori, Humberto Holmer
Scientia Medica , 2008,
Abstract: Objetivos: descrever e discutir as hipóteses etiológicas e a terapêutica do desvio septal neonatal. Fonte de dados: revis o de artigos especializados no assunto e indexados ao PubMed. Síntese dos dados: a obstru o nasal no recém-nascido é situa o de risco em virtude de este ser respirador nasal exclusivo. O desvio septal nasal neonatal é causa descrita de obstru o nessa popula o e pode estar relacionado ao trauma intrauterino ou ocorrido durante o parto. Sua incidência n o pode ser determinada com os estudos vigentes, pois há muita discrepancia nos achados. Apesar de haver resolu o espontanea em alguns casos, a interven o precoce no momento do diagnóstico é defendida por muitos autores, embasada na melhora dos sintomas e na preven o de complica es. Conclus es: como a respira o oral é inviável ao recém-nascido, nos casos de desvio de septo nasal obstrutivo os sintomas surgir o nas primeiras horas de vida. Nesses casos, o exame criterioso do nariz deve ser realizado rapidamente, se possível com endoscopia nasal. Se presente e sintomática, a deformidade deve ser corrigida o mais precocemente possível. Aims: To describe and discuss the etiology and treatment of neonatal septum deviation. Source of data: Review of articles specialized in the issue, found in PubMed. Summary of the findings: Nasal obstruction in newborn infants is a risk situation because they are obligatory nasal breathers. The nasal septum deviation is described in this population and can be related to intrauterine or delivery trauma. Its incidence cannot be determinated through the available studies, because the results are too diverse. Although there are some cases of spontaneous resolution, early intervention is defended by the majority of authors. Conclusions: Since oral respiration is not possible in newborn infants, in cases of obstructed nasal septum deviation symptoms will begin during the first hours of life. In these cases, a careful examination of the nose should be done promptly, preferably with an endoscope. If the deformity is found, and it is symptomatic, it should be repaired as soon as possible.
Perfura??o de septo nasal em paciente com pioderma gangrenoso
Maia, Camilla Bezerra da Cruz;Felix, Felippe;Paes, Vania;Azevedo, Julia Alves de;Grangeiro, Eliza Raquel Negr?o;Riccio, Jonatah Lucas N.;Rito, Helen Cruz;
International Archives of Otorhinolaryngology , 2012, DOI: 10.7162/S1809-97772012000200018
Abstract: introduction: the cocaine is obtained from the leaves of the coca (erythroxylon coca). it can be used in many ways, but the most common is the drug inhalation. the cocaine also causes vasoconstriction at nasal mucous membrane and its chronic use can cause necrosis and nasal septum perforation. pyoderma gangrenosum is an uncommon idiopathic disease characterized by ulcerations, usually observed on the legs. its diagnosis is most common an exclusion of others diseases. so far, there is no specific treatment based on evidence by randomized controlled trials. objective: describe the rare association between pyoderma gangrenosum and cocaine. case report: e. a., 27-year-old woman with destruction of nasal septum and palate who has been using a big amount of cocaine, been necessary note the difference from which disease cause de damage. final comments: also there are only three cases of pyoderma gangrenosum complicated with nasal septum perforation in cocaine users.
Absceso del septum nasal
Barril,María F; Ferolla,Fausto M; José,Pablo; Echave,Cecilia; Tomezzoli,Silvana; Fiorini,Sandra; López,Eduardo Luis;
Archivos argentinos de pediatr?-a , 2008,
Abstract: a nasal septal abscess (na) is defined as a collection of pus between the cartilage or bony septum and its normally applied mucoperichondrium or mucoperiostium. it is an uncommon disease wich should be suspected in a patient with acute onset of nasal obstruction and recent history of nasal trauma, periodontal infection or an inflammatory process of the rhinosinusal region. we report a case of an 8-year-old boy with bilateral na caused by community-acquired methicillin-resistant staphylococcus aureus(mr-co) in order to emphasize the importance of prompt diagnosis and adequate treatment to prevent the potentially dangerous spread of infection and the development of severe functional and cosmetic sequelae.
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