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Post Mortem System - Playback of the RHIC Collider  [PDF]
J. S. Laster,T. Clifford,T. D'Ottavio,A. Marusic,J. F. Skelly
Physics , 2001,
Abstract: A Post Mortem System was developed for the Relativistic Heavy Ion Collider at Brookhaven National Laboratory to provide a playback of the collider state at the time of a beam abort, quench, or other failure event. Post Mortem data is used to provide diagnostics about the failure and to improve future stores. This data is read from hardware buffers and is written directly to the main file system by Accelerator Device Objects in the front-end computers. The Post Mortem System has facilitated analysis of loss monitor and power supply data, such as beam loss during magnet quenches, dump kicker misfires and power supply malfunctions. System details and recent operating experience will be discussed.
REVIVIENDO LA CONSULTA POST-MORTEM
Armando Cortés
Colombia Médica , 2005,
Abstract: Por estos días se inaugura el “Centro de consulta post-mortem del Hospital Universitario del Valle”, una denominación más apropiada para la autopsia ver por sí mismo o cualquiera de sus sinónimos necropsia, examen post-mortem, necroscopia, o tanatopsia; todos ellos no aceptados y condicionados por factores culturales, sociales o religiosos. Estos términos han alcanzado una connotación claramente negativa en el ambiente médico y en el público general. Quizás, el mejor término sea consulta post-mortem , porque representa en verdad un examen médico después de la vida, cuyos objetivos son la búsqueda de las causas de la muerte, el análisis de la enfermedad básica, sus efectos y complicaciones y las consecuencias de la intervención médica. Nadie puede dudar de los aportes a la medicina de la consulta post-mortem. Su carácter riguroso transformó la medicina animista en el presente científico. Así aprendimos las lesiones producidas en los órganos, las anomalías asociadas con los defectos congénitos, las infecciones silenciosas o la cardiopatía en el hipotiroidismo; nos ha permitido identificar nuevas enfermedades, nuevas formas o patrones de presentación de viejas enfermedades, reconocer a ciertos agentes patógenos, conocer cómo la terapéutica cambia la historia natural de ciertas enfermedades, etc., y, en consecuencia, cómo debemos replantear los enfoques terapéuticos y de manejo; y ha dado origen a ideas para tratamientos médicos y quirúrgicos y el control de la efectividad de los tratamientos médicos. Aunque hoy casi ninguna zona de nuestro organismo es inaccesible o escapa a la exploración con los avances de la tecnología y nos permite realizar diagnósticos más precisos. Aún las nuevas técnicas de diagnóstico tienen una carga variable de subjetividad que depende de la habilidad, experiencia y conocimientos de quien los emplea, realiza o interpreta. Por tanto, es necesario utilizar esos recursos en forma racional, y con base en los datos clínicos, obtener el diagnóstico, sin deslumbrarse o confundir. El médico debe desarrollar la destreza para indagar y utilizar como herramientas de trabajo el acervo científico y el apoyo racional de la tecnología y entender qué pasa en el paciente. Nada más lejos de la realidad la creencia de que los métodos diagnósticos modernos son tan precisos que la consulta post-mortem nada puede mostrar que no haya sido identificado en vida del paciente. Los patólogos hemos demostrado que la discordancia diagnóstica entre la causa de muerte y la enfermedad de base y los hallazgos de la consulta post-mortem es significativa y ha per
The Post-Mortem Pink Teeth Phenomenon
C. Stavrianos,L. Vasiliadis,C. Papadopoulos,O. Pantelidou,K. Tolidis,P. Dagkalis
Research Journal of Biological Sciences , 2012, DOI: 10.3923/rjbsci.2011.124.127
Abstract: In certain circumstances, teeth may appear with a discoloration in post-mortem examinations. This phenomenon is called pink teeth. Pink teeth are caused by release of hemosiderin due to the breakdown of haemoglobin of red cells inside the pulp. The hemosiderin then is released inside the dentine tubules and discolour the teeth. Nevertheless, this situation can be reported in living humans, in endondontically treated teeth and in other conditions in primary teeth, etc. There are many reports of pink teeth in the literature, thus the usage of proof in Forensic odontology for a positive identification of a body remains under controversy.
Density of integral points on algebraic varieties  [PDF]
Brendan Hassett,Yuri Tschinkel
Mathematics , 2000,
Abstract: We study the distribution of integral points on log varieties.
Effects of post mortem temperature on rigor tension, shortening and pH in ostrich muscle
S StC. Botha, LC Hoffman, TJ Britz
South African Journal of Animal Science , 2008,
Abstract: Fully developed rigor mortis in muscle is characterised by maximum loss of extensibility. The course of post mortem changes in ostrich muscle was studied by following isometric tension, shortening and change in pH during the first 24 h post mortem within muscle strips from the muscularis gastrocnemius, pars interna at constant temperatures of 7 °C and 37 °C. Maximum shortening was significantly higher at 37 °C (33.4 ± 3.57%) than at 7 °C (10.7 ± 2.63%). The rate of rigor development was temperature dependent, reaching a maximum tension at 4.08 ± 3.89 h post mortem in muscle strips at 37 °C; while at 7 °C maximum tension was reached at 10.5 ± 6.47 h post mortem. It was concluded that the completion of rigor occurred at the point of minimum pH.
In Vivo and post-mortem performances of Marchigiana and Romagnola Breeds
M. F. Trombetta,S. Mattii,A. Falaschini,F. Sbarra
Italian Journal of Animal Science , 2010, DOI: 10.4081/ijas.2007.1s.484
Abstract: The aim of these studies was to evaluate the in vivo and post-mortem performances of Marchigiana and Romagnola cattle. The results provide updated information that suggest that the selection index of some parameters should be revised to improve the dressing, which is one of the limitations of these breeds.
Comparison of Magnetic Resonance Imaging in Live vs. Post Mortem Rat Brains  [PDF]
Ipek Oguz, Richard Yaxley, Francois Budin, Marion Hoogstoel, Joohwi Lee, Eric Maltbie, Wen Liu, Fulton T. Crews
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0071027
Abstract: Magnetic Resonance Imaging (MRI) is an increasingly popular technique for examining neurobiology in rodents because it is both noninvasive and nondestructive. MRI scans can be acquired from either live or post mortem specimens. In vivo scans have a key advantage in that subjects can be scanned at multiple time-points in longitudinal studies. However, repeated exposure to anesthesia and stress may confound studies. In contrast, post mortem scans offer improved image quality and increased signal-to-noise ratio (SNR) due to several key advantages: First, the images are not disrupted by motion and pulsation artifacts. Second, they allow the brain tissue to be perfused with contrast agents, enhancing tissue contrast. Third, they allow longer image acquisition times, yielding higher resolution and/or improved SNR. Fourth, they allow assessment of groups of animals at the same age without scheduling complications. Despite these advantages, researchers are often skeptical of post mortem MRI scans because of uncertainty about whether the fixation process alters the MRI measurements. To address these concerns, we present a thorough comparative study of in vivo and post mortem MRI scans in healthy male Wistar rats at three age points throughout adolescence (postnatal days 28 through 80). For each subject, an in vivo scan was acquired, followed by perfusion and two post mortem scans at two different MRI facilities. The goal was to assess robustness of measurements, to detect any changes in volumetric measurements after fixation, and to investigate any differential bias that may exist between image acquisition techniques. We present this volumetric analysis for comparison of 22 anatomical structures between in vivo and post mortem scans. No significant changes in volumetric measurements were detected; however, as hypothesized, the image quality is dramatically improved in post mortem scans. These findings illustrate the validity and utility of using post mortem scans in volumetric neurobiological studies.
Partitioning the Proteome: Phase Separation for Targeted Analysis of Membrane Proteins in Human Post-Mortem Brain  [PDF]
Jane A. English, Bruno Manadas, Caitriona Scaife, David R. Cotter, Michael J. Dunn
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0039509
Abstract: Neuroproteomics is a powerful platform for targeted and hypothesis driven research, providing comprehensive insights into cellular and sub-cellular disease states, Gene × Environmental effects, and cellular response to medication effects in human, animal, and cell culture models. Analysis of sub-proteomes is becoming increasingly important in clinical proteomics, enriching for otherwise undetectable proteins that are possible markers for disease. Membrane proteins are one such sub-proteome class that merit in-depth targeted analysis, particularly in psychiatric disorders. As membrane proteins are notoriously difficult to analyse using traditional proteomics methods, we evaluate a paradigm to enrich for and study membrane proteins from human post-mortem brain tissue. This is the first study to extensively characterise the integral trans-membrane spanning proteins present in human brain. Using Triton X-114 phase separation and LC-MS/MS analysis, we enriched for and identified 494 membrane proteins, with 194 trans-membrane helices present, ranging from 1 to 21 helices per protein. Isolated proteins included glutamate receptors, G proteins, voltage gated and calcium channels, synaptic proteins, and myelin proteins, all of which warrant quantitative proteomic investigation in psychiatric and neurological disorders. Overall, our sub-proteome analysis reduced sample complexity and enriched for integral membrane proteins by 2.3 fold, thus allowing for more manageable, reproducible, and targeted proteomics in case vs. control biomarker studies. This study provides a valuable reference for future neuroproteomic investigations of membrane proteins, and validates the use Triton X-114 detergent phase extraction on human post mortem brain.
Post-Mortem Projections: Medieval Mystical Resurrection and the Return of Tupac Shakur  [cached]
Alicia Spencer-Hall
Opticon1826 , 2012, DOI: 10.5334/opt.af
Abstract: Medieval hagiographies abound with tales of post-mortem visits and miracles by saints. The saint was a powerful religious individual both in life and in death, a conduit of divine grace and lightning rod for Christian fervour. With her post-mortem presence, the presumptive boundary between living and dead, spirit and flesh, is rent apart: showing the reality of the hereafter and shattering the fantasies of the mortal world. The phenomenon of a glorified individual returning to a worshipful community after their apparent mortal expiration is not just medieval. In April 2012, the rapper Tupac Shakur “performed” on stage at the Coachella music festival. Tupac was murdered in 1996; his ghostly presence was the result of a hologram. His holographic form, the “Pac-O-Gram”, took to the stage to a breathless crowd of fans. The holographic performance is a product of technological advances. Yet reports of the holographic performance were filled with references to Tupac’s “resurrection”, a significant word choice, and one which links the rapper’s return with medieval hagiography more than the advance of technology. What can an examination of the modern example of the Pac-O-Gram and examples drawn from medieval hagiography of the dead returning to life add to each other?
Comparison of different methods for delayed post-mortem diagnosis of falciparum malaria
Nicole Berens-Riha, Inga Sinicina, Erna Fleischmann, Thomas L?scher
Malaria Journal , 2009, DOI: 10.1186/1475-2875-8-244
Abstract: In order to evaluate different methods for the post-mortem diagnosis of Plasmodium falciparum malaria in non-immunes, a study was performed on the basis of forensic autopsies of corpses examined at variable intervals after death in five cases of fatal malaria (with an interval of four hours to five days), and in 20 cases of deaths unrelated to malaria. Detection of parasite DNA by PCR and an immunochromatographic test (ICT) based upon the detection of P. falciparum histidine-rich protein 2 (PfHRP2) were compared with the results of microscopic examination of smears from cadaveric blood, histopathological findings, and autopsy results.In all cases of fatal malaria, post-mortem findings were unsuspicious for the final diagnosis, and autoptic investigations, including histopathology, were only performed because of additional information by police officers and neighbours. Macroscopic findings during autopsy were unspecific. Histopathology confirmed sequestration of erythrocytes and pigment in macrophages in most organs in four patients (not evaluable in one patient due to autolysis). Microscopy of cadaveric blood smears revealed remnants of intraerythrocytic parasites, and was compromised or impossible due to autolysis in two cases. PCR and ICT performed with cadaveric blood were positive in all malaria patients and negative in all controls.In non-immune fatalities with unclear anamnesis, ICT can be recommended as a sensitive and specific tool for post-mortem malaria diagnosis, which is easier and faster than microscopy, and also applicable when microscopic examination is impossible due to autolysis. PCR is more expensive and time-consuming, but may be used as confirmatory test. In highly endemic areas where asymptomatic parasitaemia is common, confirmation of the diagnosis of malaria as the cause of death has to rely on histopathological findings.Malaria is endemic in 109 countries with a disease burden of approximately 250 million clinical cases and 1 million fataliti
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