oalib
Search Results: 1 - 10 of 100 matches for " "
All listed articles are free for downloading (OA Articles)
Page 1 /100
Display every page Item
Neumonitis por hipersensibilidad Pneumonitis related to hypersensitivity  [cached]
Beatriz González Freijanes,Emilio Buchaca Faxas,Francisco Fernández Valdés,Lays Rodríguez Amador
Revista Cubana de Medicina , 2009,
Abstract: Se presentó una paciente con antecedentes patológicos personales de asma bronquial leve persistente y de dermatitis atópica. Acudió por tener fiebre de 60 d de evolución, tos, disnea, anorexia y pérdida de peso, con empeoramiento progresivo. Se diagnosticó neumonitis por hipersensibilidad después de realizar estudios de imágenes e histológicos. Se describió la evolución clínica y radiológica. Authors present the case of a woman with personal pathologic backgrounds of persistent light bronchial asthma and of an atopic dermatitis. She came to our service by fever of 60 days of evolution, cough, dyspnea, anorexia, and weight loss with a progressive worsening. A hypersensitivity pneumonitis was diagnosed after imaging and histological studies. Clinical and radiological course was described.
Pegylated interferon induced interstitial pneumonitis in a patient with hepatitis C infection
Torres Macho,J.; Jara Chinarro,B.; Suárez Aliaga,B.; Gámez Díez,S.; García de Casasola,G.; Cuenca Morón,B. de;
Revista Espa?ola de Enfermedades Digestivas , 2010, DOI: 10.4321/S1130-01082010001000009
Abstract: pegylated interferon and ribavirin is the treatment of choice in patients with chronic hepatitis c infection. the most common side effects of interferon therapy are flu-like symptoms and psychiatric disorders. pneumonitis is a less frequent complication associated with non-negligible mortality. we herein report a case of interferon associated pneumonitis in a patient with non-severe clinical symptoms and a normal chest radiography. physicians should be aware of this entity during the differential diagnosis of respiratory symptoms in patients receiving treatment with interferon due to its high morbimortality and good resolution and outcome after drug withdrawal.
Neumonitis por hipersensibilidad (alveolitis alérgica extrínseca) Hypersensitivity Pneumonitis (extrinsic allergic alveolitis)  [cached]
P. Cebollero,S. Echechipía,A. Echegoyen,M. P. Lorente
Anales del Sistema Sanitario de Navarra , 2005,
Abstract: El pulmón del granjero se describió por primera vez en 1932. Podemos definir la neumonitis por hipersensibilidad como una enfermedad pulmonar y sistémica que cursa con disnea y tos, y que se produce por la inflamación de tipo inmunológico de las paredes alveolares y vías aéreas terminales y que es secundaria a la inhalación repetida de una variedad de antígenos por un huésped susceptible. Puede decirse que es una enfermedad infradiagnosticada y sólo un alto grado de sospecha clínica y una historia detallada de la exposición pueden llevar a un diagnóstico precoz y un tratamiento satisfactorio. Una combinación entre los hallazgos clínico-radiológicos, funcionales, citológicos o anatonomopatológicos, en algunos casos, nos llevarán al diagnóstico. El tratamiento se funda en la evitación del agente causal y, en los casos más graves, la administración de tratamiento corticoideo sistémico. Farmer’s lung was first described in 1932. We can define hypersensitivity pneumonitis as a pulmonary and systemic disease that is accompanied by dyspnoea and coughing; it is caused by an immunological type of inflammation of the alveolar walls and the terminal airways and it is secondary to the repeated inhalation of a variety of antigens by a susceptible host. It can be said that it is an underdiagnosed disease and only a high degree of clinical manifestations and a detailed history of exposure can lead to an early diagnosis and satisfactory treatment. A combination among clinical-radiological, functional, cytological or pathological findings leads in some cases to a diagnosis. Treatment is based on avoiding further exposure to the causal agent and in the more serious cases the administration of systemic corticoid treatment.
Neumonía intersticial asociada a sirolimus en un paciente con trasplante hepático Sirolimus-associated interstitial pneumonitis in a liver transplant recipient  [cached]
Marie Claire Berrouet,Julián Miguel Aristizábal,Juan Carlos Restrepo,Gonzalo Correa
Acta Medica Colombiana , 2008,
Abstract: Con la utilización de sirolimus en pacientes trasplantados, se han reportado casos de neumonitis intersticial, bronquiolitis obliterante y neumonía organizada. Nosotros describimos un caso de toxicidad pulmonar asociada al uso de sirolimus en un paciente de 59 a os con trasplante hepático, revisamos los reportes de caso donde se describía toxicidad pulmonar asociada al uso de sirolimus en pacientes con trasplante hepático, con el objetivo de encontrar similitudes en factores de riesgo, manifestaciones clínicas y desenlaces. De los cinco casos reportados desde enero de 2000, incluyendo el presente, encontramos que las manifestaciones clínicas fueron similares presentándose fiebre, disnea, fatiga, tos y hemoptisis. Con la suspensión del medicamento, los pacientes resolvieron sus signos, síntomas y hallazgos imagenológicos. La toxicidad pulmonar asociada a sirolimus debe ser considerada como diagnóstico diferencial de aquellos pacientes con trasplante hepático que reciban este medicamento y presenten manifestaciones respiratorias, pues la suspensión del medicamento lleva a la resolución del cuadro. Sirolimus is an immunosuppressive drug that has been used during the past few years. Sirolimus is indicated in rescue therapies and to reduce the secondary toxic effects of calcineurin inhibitors. This drug has been associated with infrequent but severe pulmonary toxicity. Cases of interstitial pneumonitis, bronchiolitis obliterans with organizing pneumonia, and alveolar proteinosis have been described. We describe a case of pulmonary toxicity associated with the use of sirolimus in a 59-yr-old liver transplant recipient. We also review all reported cases of sirolimus-associated lung toxicity among liver transplantation recipients, with the intention of understanding the risk factors, the clinical picture and the outcomes of this complication. Five cases have been reported since January 2000, including the present case. Clinical presentation is similar, with fever, dyspnea, fatigue, cough, and hemoptysis. Discontinuation of the drug led to resolution of clinical and radiographic findings. Sirolimus-induced pulmonary toxicity is a serious condition and should be considered in the differential diagnosis of liver recipients presenting with respiratory findings. Discontinuation of the drug is associated with resolution of the pulmonary compromise.
Interstitial Pneumonitis after Combination Therapy with Pegylated Interferon α-2b and Ribavirin for Chronic Hepatitis C  [PDF]
Yung Che Chen,Sheng-Nan Lu,Meng-Chih Lin
Chang Gung Medical Journal , 2007,
Abstract: Pulmonary toxicity is a rare but potentially fatal side effect occurring during interferon(IFN) α treatment for chronic hepatitis C. We present a 47-year-old woman who had chronichepatitis C and was treated with pegylated IFN α-2b in combination with ribavirin, with agood virological response by week 10 of therapy. Then the patient began to complain of dyspneaon exertion and a dry cough. A diagnosis of interstitial pneumonitis was made accordingto the results of chest X-rays, high resolution computed tomography and bronchoalveolarlavage analysis. Pegylated IFN α-2b has a longer absorption and elimination half-lifethan conventional IFN α-2b and a comparable potency to conventional IFN α-2b. Althoughthe tolerability of pegylated IFN α is comparable to that of conventional IFN α, pulmonarytoxicity may occur more frequently with long-acting pegylated IFN α therapy at an inappropriatelyhigh dose. Based on a MEDLINE search up to 2004, we believe that this is the firstreported case of a patient recovering from interstitial pneumonitis associated with pegylatedIFN α-2b for chronic hepatitis C. Physicians should keep in mind the possibility of this complicationwhen treating chronic hepatitis C patients with pegylated IFN α-2b and ribavirincombinational therapy
Retinopatía asociada a interferón pegilado y ribavirina en pacientes con hepatitis C Pegylated interferon and ribavirin associated retinopathy in patients with hepatitis C
C. Burgue?o-Monta?és,R. Pérez-álvarez
Archivos de la Sociedad Espa?ola de Oftalmología , 2011,
Abstract: Caso clínico: Se describen dos pacientes portadores de hepatitis C y tratados con interferón pegilado y ribavirina que desarrollaron múltiples exudados algodonosos en la retina de ambos ojos. El cuadro oftalmológico fue etiquetado de retinopatía asociada a interferón pegilado y en un caso cedió espontáneamente y en otro tras su retirada. Discusión: El interferón es una citocina inmunomoduladora utilizada como primera línea de tratamiento de la hepatitis C. Numerosos efectos adversos han sido descritos, pero los oculares son menos conocidos. Consideramos necesario el seguimiento oftalmológico sistemático durante el tratamiento con interferón por la posibilidad de detectar dichas complicaciones, algunas graves. Case report: We describe two patients with chronic hepatitis C, treated with pegylated interferon and ribavirin, who developed multiple cotton-wool spots in the retina of both eyes. The ocular findings were identified as pegylated interferon associated retinopathy, and in one case spontaneously resolved and in the other after the treatment was withdrawn. Discussion: Interferon is an immunomodulating cytokine used as a first line treatment of hepatitis C. Numerous adverse effects have been reported, but ocular ones are less known. We believe that periodic ophthalmological examinations during this treatment are required in order to detect these complications, which can be serious.
Fatal pneumonia by Legionella in a farmer with hypersensitivity pneumonitis Neumonía por Legionella con desenlace fatal en un granjero con neumonitis por hipersensibilidad  [cached]
Vega García López,Elena Ordoqui García,Teresa Ferrer Gimeno,Jacinto Irisarri Orta
Medicina y Seguridad del Trabajo , 2009,
Abstract: Background: The retrospective investigation of a fatal sporadic Legionnaires' disease identified an unknown case of occupational hypersensitivity pneumonitis in a swine breeder. Methods: Chest high-resolution computed tomography, bronchoalveolar lavage, lung biopsy, arterial gasometry, pulmonary function tests and autopsy were performed. It was studied the presence of Legionella by serology and risk water samples were analyzed to identify the Legionella's source. Results: HP and Legionella pneumophila pneumonia diagnostics were confirmed. Lung fibrosis, a restrictive functional pattern, decreased diffusion, hypoxemia and bronchoalveolar lavage lymphocytosis were evidenced. Legionella′s source was detected in a shower and a positive serology in the patient. Autopsy verified pulmonary fibrosis and the septic shock leaded to Legionella causing the death. Conclusions: Chronic cough and pulmonary infiltrates in a farmer should suspect the presence of hypersensitivity pneumonitis. Later diagnosis carries a worse prognosis, the offending antigens exposure can't be avoided and fibrotic stage enhanced opportunity infection disease. Introducción: La investigación retrospectiva sobre un fallecimiento aislado por Legionelosis, hizo aflorar un caso de neumonitis por hipersensibilidad en un granjero cuidador de cerdos. Métodos: Se realizaron las siguientes pruebas: tomografía axial computerizada de alta resolución, lavado broncoalveolar, biopsia pulmonar, gasometría arterial, pruebas de función respiratoria y autopsia. Se estudió la presencia de Legionella por serología y se analizaron las muestras de fuentes de riesgo para identificar el foco de Legionella. Resultados: El estudio confirmó los diagnósticos de neumonitis por hipersensibilidad y neumonía por Legionella pneumophila. Las pruebas realizadas objetivaron la fibrosis pulmonar, un patrón respiratorio funcional restrictivo, un descenso de la difusión pulmonar, hipoxemia y la presencia de linfocitosis en el lavado broncoalveolar. Se detectó el foco de Legionella en una ducha y la serología fue positiva en el paciente. La autopsia confirmó la fibrosis pulmonar y el shock séptico por Legionella que causó la muerte. Conclusiones: La presencia de tos crónica e infiltrados pulmonares en un granjero debería hacer sospechar la existencia de una neumonitis por hipersensibilidad. Retrasar su diagnóstico conlleva un peor pronóstico, impide evitar la exposición a los antígenos causantes del cuadro y permite el avance de la fibrosis pulmonar facilitando la aparición de infecciones oportunistas.
Neumonitis secundaria a metotrexate
Sáenz Abad,D.; Ruiz-Ruiz,F. J.; Monón Ballarín,S.; Mozota Duarte,J.; Marquina Barcos,A.;
Anales de Medicina Interna , 2008, DOI: 10.4321/S0212-71992008000100007
Abstract: methotrexate (mtx) is a folic acid antagonist that inhibits cellular reproduction. mtx has been shown to be an effective anti-inflammatory agent. acute interstitial pneumonitis is the main pulmonary side effect during mtx treatment. we report a case of mtx pneumonitis in a 56-year old woman with autoimmune thrombocytopenia who presented with subacute nonproductive cough, dyspnea at rest, fever, and malaise. chest roentgenogram demonstrated bilateral diffuse interstitial and alveolar infiltration. infectious diseases were ruled out and methotrexte-induced pneumonitis was suspected. mtx was discontinuated and methylprednisolone was prescribed. patient improved progressively. after eight weeks, radiologic abnormalities and symptoms had disappeared.
Neumonitis por hipersensibilidad
González Freijanes,Beatriz; Buchaca Faxas,Emilio; Fernández Valdés,Francisco; Rodríguez Amador,Lays; Chong López,Agustín; Pe?a Casanova,Aisa;
Revista Cubana de Medicina , 2009,
Abstract: authors present the case of a woman with personal pathologic backgrounds of persistent light bronchial asthma and of an atopic dermatitis. she came to our service by fever of 60 days of evolution, cough, dyspnea, anorexia, and weight loss with a progressive worsening. a hypersensitivity pneumonitis was diagnosed after imaging and histological studies. clinical and radiological course was described.
Airbag Pneumonitis
Raghav Govindarajan,Gustavo Ferrer,Laurence A. Smolley,Eduardo Araujo Oliveira,Franck Rahaghi
Case Reports in Medicine , 2010, DOI: 10.1155/2010/498569
Abstract: The widespread and mandatory use of airbags has resulted in various patterns of injuries and complications unique to their use. Airbags have been implicated in a spectrum of pulmonary conditions ranging from exacerbation of asthma, reactive airway diseases to new onset asthma. We report a case of inhalational chemical pneumonitis that developed after exposure to the airbag fumes.
Page 1 /100
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.