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Giant adrenal myelolipoma: A case report  [PDF]
P Gurung,MR Joshi,S Hirachand,M Lakhey
Journal of Kathmandu Medical College , 2013, DOI: 10.3126/jkmc.v2i1.10554
Abstract: Adrenal myelolipomas are rare benign tumors. Most are detected incidentally on imaging for non adrenal relatedsymptoms. We report a case of a 78 year old female who presented with non- specifi c complaint of itching all over the bodyand a palpable abdominal mass. CT scan abdomen revealed a large right-sided retroperitoneal mass with thin capsulemeasuring 20.8x15.4x12.7cm. Differential diagnoses considered were retroperitoneal liposarcoma, retroperitonealteratoma and retroperitoneal myelolipoma. The tumor was resected and sent for histopathological examination.Microscopic examination revealed mature adipocytes, islands of hematopoietic tissue and compressed adrenal tissue atthe periphery clinching a diagnosis of adrenal myelolipoma. DOI: http://dx.doi.org/10.3126/jkmc.v2i1.10554 Journal of Kathmandu Medical College , Vol. 2, No. 1, Issue 3, Jan.-Mar., 2013, Page: 33-35
Giant adrenal myelolipoma with a spontaneous rupture: report of a case
Sergio Renato Pais Costa,Sergio Henrique Couto Horta,Alexandre Cruz Henriques
Einstein (S?o Paulo) , 2009,
Abstract: Myelolipoma is a benign tumor of the adrenal cortex, which is non-functioning and often asymptomatic. It is generally diagnosed in imaging tests by chance. Rupture and bleeding of myelolipoma is an infrequent complication, and may lead to the formation of a hematoma or, less usually, result in a massive retroperitoneal hemorrhage. The compression of adjacent structures by retroperitoneal hematoma of adrenal origin is possible but not frequent. Indications for surgery continue to be a difficult and controversial decision, since a conservative treatment and a watchful waiting may be indicated in some cases. However, the surgical procedure has been more precisely indicated to symptomatic patients (pain or infection) or even to uncertain diagnosis (malignant neoplasm). The authors present a case of a giant myelolipoma of the adrenal gland that presented both complicated spontaneous rupture (abdominal pain) and uncertain diagnosis by radiological images (computed tomography). The patient underwent a surgical resection with favorable postoperative outcome and pain relief.
Giant secreting adrenal myelolipoma in a man: a case report
Alfio Brogna, Giuseppe Scalisi, Rosario Ferrara, Anna M Bucceri
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-298
Abstract: A 52-year-old Caucasian man of medium build who had had moderate hypertension for three years presented to our hospital. He had no other significant symptoms. His hypertension was pharmacologically treated. He came to our hospital to undergo abdominal ultrasonography during a clinical checkup. The ultrasound scan showed the presence of a voluminous hyperechoic mass interposed between the spleen and the left kidney. It was reported as a myelolipoma of the left kidney on the basis of its structural characteristics and position. Computed tomography confirmed our diagnosis. All preoperative biochemical tests were normal, with the exception of high serum cortisol, which was being overproduced by the lesion and was probably responsible for the patient's hypertension. He underwent successful surgery, and his postoperative course was uneventful. The pathologic examination of the lesion confirmed the diagnosis of adrenal myelolipoma. The patient's blood pressure returned to within the normal range.The "incidental" discovery of an adrenal mass requires careful diagnostic study to plan adequate therapeutic management. Both of the primary investigations at our disposal, ultrasound and blood tests (adrenal hormones), helped in rendering the diagnosis and allowed us to move toward the most appropriate treatment, taking into account the size of the tumor and its probable hormonal production.The myelolipoma is a rare, benign neoplasm composed of mature adipocytes and hematopoietic tissue. It was first described by Gierke in 1905 and subsequently by Oberling in 1929, who used the term "myelolipoma" [1]. In the past, the finding of adrenal lesions was made possible by autopsy or by clinical presentation, related either to the massive growth of the gland or to altered hormone production. Today these tumors can be discovered incidentally because of the wide use of diagnostic imaging methods, such as ultrasonography (US), computed tomography (CT) and magnetic resonance imaging [2]. Alth
Giant adrenal myelolipoma  [cached]
Fernandes Gwendolyn,Gupta Rajib,Kandalkar Bhuvaneshwari
Indian Journal of Pathology and Microbiology , 2010,
Abstract: Adrenal myelolipoma is a rare benign tumor composed of adipose and hematopoietic tissue. Most tumors are small in size and incidentally detected. We report a case of giant adrenal myelolipoma weighing 2200 gms which was diagnosed on radiology as a liposarcoma. This case is unusual in view of the large size and presence of bony spicules. To the best of our knowledge, not more than 10 giant adrenal myelolipoma cases have been reported in literature.
Adrenal Myelolipoma- A Rare Case Report
Vijayalaxmi V. Suranagi,Prakash R.Malur,Hema B.Bannur,Reshma Davanageri
Al Ameen Journal of Medical Sciences , 2009,
Abstract: Adrenal myelolipoma (AML) is a rare benign tumour composed of mature adipose tissue and hematopoietic tissue. Very few cases have been reported. Most of these patients are asymptomatic. We present a rare case of Adrenal Myelolipoma where the patient presented with hypertension and a clinical suspicion of Pheochromocytoma, which turned out to be an Adrenal myelolipoma. Adrenal myelolipoma is a rare entity, not encountered frequently and can occur as an incidental finding. Awareness regarding this entity is very much essential to exclude surgical exploration or extensive surgery.
Giant lipoma of the adrenal gland: a case report
Rashmi D Patel, Aruna V Vanikar, Pranjal R Modi
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-78
Abstract: We report an incidentally detected giant adrenal lipoma in a 43-year-old Asian man with a six year history of hypertension. He had a myocardial infarction one year earlier, for which he was taking an antiplatelet agent in addition to antihypertensive medication.The tumor was detected by computed tomography and magnetic resonance imaging, and was a large, well-defined, altered signal intensity lesion 12 cm in size in the right suprarenal region. The tumor was resected laparoscopically and sent for histopathologic evaluation. It measured 15 cm × 11.5 cm × 6.5 cm on gross examination, weighed 810 g and had a homogenous yellow cut surface. The postoperative course was smooth. Microscopy revealed mature adipose tissue with myxoid degeneration. Over the course of a four month follow-up the patient recovered.Giant lipoma of the adrenal gland, a benign tumor, is rare compared with myelolipoma. Improved radiologic modalities have led to increased reporting of these benign tumors. Laparoscopic removal of the tumor has helped in early recovery and in reinstating patients to normal lives.Lipomatous tumors of the adrenal gland are rare. Improved diagnostic modalities, including high-resolution ultrasonography, computed tomography (CT) and magnetic resonance imaging (MRI), have led to increased reporting and management of such tumors. We report one such case of an incidentally detected adrenal lipoma.A 43-year-old Asian man was incidentally detected to have a loose, well-defined, homogenously enhancing soft tissue density lesion in the right adrenal gland. This lesion was found while the patient was undergoing investigations for hypertension of six years' duration being controlled with α- and β-blockers and a diuretic. The patient had a history of myocardial infarction nine earlier for which he underwent coronary angioplasty and he was taking an antiplatelet agent.During this admission, he had undergone ultrasonography of the abdomen, which revealed an adrenal mass. No other sign
Simultaneous adrenal and extra-adrenal myelolipoma – an uncommon incident: case report and review of the literature
Derek Zieker, Ingmar K?nigsrainer, Stephan Miller, Ulrich Vogel, Karl Sotlar, Wolfgang Steurer, Alfred K?nigsrainer, Thorsten G Lehmann
World Journal of Surgical Oncology , 2008, DOI: 10.1186/1477-7819-6-72
Abstract: We report a very seldom case of a simultaneous myelolipoma of the adrenal gland in association with an extra-adrenal myelolipoma in an 75-year-old man. With a review of the literature we describe and discuss the aetiology, differential diagnosis and treatment of patients with respect to adrenal and extra-adrenal lesions.The appearance of a simultaneous adrenal and extra-adrenal myelolipoma is a rare incident. We conclude that such lesions should be considered in the differential diagnosis of a fat-containing tumour in the retroperitoneal tissue/compartment.The incidence of extra-adrenal myelolipomas is rare. Only about 50 cases have been described in the literature within the last 2 decades. Myelolipomas are benign tumours and are composed of haematopoietic cells and adipose tissue [1-4]. They are usually non-functioning asymptomatic tumours and often found incidentally on radiographic studies [5]. Mostly myelolipomas are located in the adrenal gland. A very infrequent finding is the incidence of a myelolipoma of the adrenal gland simultaneously with an extra-adrenal myelolipoma. Appearance of myelolipomas outside of the adrenal gland might be difficult to identify, since other soft tissue tumours such as well-differentiated liposarcomas appear morphological almost identical [1-3,6-10]. We report an unusual case of a myelolipoma of the adrenal gland in association with an extra-adrenal myelolipoma. This case sensitises the importance of this combination as a pitfall in the correct diagnosis and management of patients with respect to adrenal and extra-adrenal lesions.A 75-year-old man with a history of persisting abdominal pain and mild diarrhoea for three months was referred by a general practitioner to the hospital. During this period the patient observed a weight loss of 2 kg, but did not show any B symptoms. A colonoscopy was performed without pathological findings. A subsequent CT examination of the abdomen showed two separate fat-containing retroperitoneal mass
Mielolipoma adrenal gigante
Pareja Megía,Ma Jesús; Barrero Candau,Rafael; Medina Pérez,Manuel; Valero Puerta,Juan Antonio;
Archivos Espa?oles de Urología (Ed. impresa) , 2005, DOI: 10.4321/S0004-06142005000400014
Abstract: objective: we report a case of a giant myelolipoma of the adrenal gland methods/results: a case of a giant myelolipoma of the adrenal gland, an uncommon non-functioning tumour of the adrenal cortex comprised of haematopoietic and adipose tissue, that had been detected incidentally during evaluation with ct because of its characteristic fatty composition. the clinical features, diagnosis and treatment are discussed.
Giant adrenal myelolipoma: Incidentaloma with a rare incidental association
Wani Nisar,Kosar Tasleem,Rawa Ijaz,Qayum Abdul
Urology Annals , 2010,
Abstract: Adrenal myelolipoma is an unusual, benign and biochemically inactive tumor that is composed of mature adipose and hematopoietic tissue. It is usually diagnosed accidentally and nowadays much more frequently because of widespread use of ultrasonography, computed tomography (CT) and magnetic resonance imaging. Adrenal myelolipoma is usually unilateral and asymptomatic, though known to be associated with obesity, hypertension, endocrinological disorders and some malignancies. We report herein two cases of right-sided giant adrenal myelolipoma diagnosed by multidetector-row CT. One patient was symptomatic because of a large mass in the right upper abdomen, which on imaging with CT was seen to be right adrenal myelolipoma. Another patient had a large left side Bochdalek hernia and right adrenal myelolipoma was incidentally discovered on CT.
Mielolipoma suprarrenal: reporte de un caso y revisión de la literatura Adrenal myelolipoma: case report and literature review
Roosevelt Fajardo,Laura Kattah,Iván Rojas,Olga Lucía Jaimes
Revista Colombiana de Cirugía , 2009,
Abstract: El mielolipoma es un tumor poco frecuente, benigno y, generalmente, asintomático, cuyo hallazgo radiológico suele ser incidental. En ocasiones, puede ser sintomático, en especial cuando el tumor alcanza un gran tama o y se manifiesta con dolor abdominal. Se ha encontrado correlación con causas de hipertensión secundaria por su asociación esporádica con feocromocitoma y aldosteronoma. Reportamos un caso de adenoma asociado a mielolipoma en un paciente con hipertensión de difícil manejo. Adrenal myelolipoma is an uncommon and benign tumor which is generally asymptomatic. The tumor is frequently discovered as an incidental finding. It can evolve with clinical manifestations like abdominal pain, particularly when the tumor reaches a large size. Alternatively it can show association with causes of secondary hyprtension such as pheochromocytoma and aldosterone-producing adenoma. We report a case of an adrenal adenoma associated with myelolipoma in a patient with history of ten years of refractory hypertension.
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