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Calcifying Epithelial Odontogenic Tumor  [PDF]
Olavo Hoston Gon?alves Pereira,Laura Priscila Barboza de Carvalho,Vilson Lacerda Brasileiro Junior,Cláudia Roberta Leite Vieira de Figueiredo
Case Reports in Pathology , 2013, DOI: 10.1155/2013/725380
Abstract: The calcifying epithelial odontogenic tumor (CEOT) is a rare benign epithelial odontogenic neoplasm of slow growth that is locally aggressive and tends to invade bone and adjacent soft tissue. Here is reported the case of a 21-year-old female patient with a CEOT in the left mandibular posterior region. The computerized tomography in coronal plane revealed a hypodense lesion in the posterior region of the left mandibular body with hyperdense areas inside and was associated with element 37. An incisional biopsy of the lesion was performed and the histopathological analysis revealed the presence of layers of epithelial odontogenic cells that formed prominent intercellular bridges. A large quantity of extracellular, eosinophilic, and amyloid-like material and an occasional formation of concentric calcifications (Liesegang rings) were also found. The histopathological diagnosis was a Pindborg tumor. Resection of the tumor with a safety margin was performed and after 6 months of follow-up there has been no sign of recurrence of the lesion. 1. Introduction The calcifying epithelial odontogenic tumor (CEOT) or Pindborg tumor is a rare benign epithelial odontogenic neoplasm [1, 2], with approximately 200 reported cases in the literature [3]. In general it occurs as a slow-growing tumor [4], associated with an impacted tooth in the posterior mandibular region [5, 6]. This occurs predominantly between the fourth and fifth decades of life, with no preference of gender [2–4]. Radiographically, CEOT is characterized by a uni- or multilocular lesion that often shows a mixed radiolucent-radiopaque pattern [6]. Treatment consists in the surgical removal of the lesion, with recurrence in 14% of cases [5]. The prognosis is considered good [6]. 2. Case Report A 21-year-old black female patient sought treatment at the Oral and Maxillofacial Trauma Surgery Unit, with swelling in the mandibular left posterior region. While performing the intraoral physical exam an asymptomatic hardened exophytic nodule was found in region 37 (Figure 1). Figure 1: Intraoral aspect of the lesion, characterized by a hardened nodular and exophytic mass in the mandibular body, on the left side. The patient reported a clinical evolution of only five months of the lesion. A radiographic exam revealed a diffuse radiolucent, unilocular lesion, associated with region 37, yet including the distal root of region 36 up to the crown of region 38 (Figure 2). Using a computerized tomography in coronal section, it was possible to observe that it was a question of a local hypodense lesion in the mandibular
The Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor): A Case Report
Mehmet Cemal Akay, Ayhan Tetik, Mert Zeytinoglu
Open Access Library Journal (OALib Journal) , 2014, DOI: 10.4236/oalib.1101036
Abstract: Calcifying Epithelial Odontogenic Tumor (CEOT) is a rare benign odontogenic tumor that was first described by Pindborg in 1955. It accounts for less than 1% of all odontogenic neoplasms. This lesion is a locally aggressive benign odontogenic neoplasm arising from epithelial tissue. The radiographic appearance is characterized by uni- or multilocular radiolucent areas with radiopaque masses of varying sizes; there is a frequent association with an unerupted tooth. Most CEOT are intraosseous lesions which are most common in the mandible, with most of these occurring in the molar and premolar regions of the mandible. Malignant transformation and metastasis is rare. ?The aim of the current report was to describe the clinical radiological and histopathological findings in a case of mandibular CEOT.
Extension of Calcifying Epithelial Odontogenic Tumor to the Maxillary Sinus: A Case Report  [PDF]
Mauricio Carrero, Luis Junquera, Juan Carlos de Vicente, Florentino Fresno
Open Journal of Stomatology (OJST) , 2014, DOI: 10.4236/ojst.2014.45039
Abstract: The calcifying epithelial odontogenic tumor (CEOT) is a rare and benign odontogenic epithelial neoplasm. This tumor accounts for less than 1% of all odontogenic tumors. It normally affects patients between 30 and 50 years old, and it is typically located in the posterior region of the mandible. Involvement of the maxillary sinus has previously been published only in six cases. This report presents a single case of CEOT that invades the maxillary sinus in a 69-year-old male. We performed a left partial maxillectomy and immediate reconstruction of the defect with a temporalis muscle flap. A comprehensive immunohistochemical study was reported. No recurrences have been found after 8 years of follow-up.
Mixed odontogenic tumor: Ameloblastoma and calcifying epithelial odontogenic tumor
Etit Demet,Uyaroglu Mehmet,Erdogan Nezahat
Indian Journal of Pathology and Microbiology , 2010,
Abstract: Odontogenic tumors constitute a group of heterogeneous disease derived from epithelial, mesenchymal and/or ectomesenchymal elements. Ameloblastoma is the best known and the most frequent form of odontogenic tumors. Calcifying epithelial odontogenic tumor (CEOT), known as Pindborg tumor, is locally invasive lesion which has a characteristic amiloid deposition. Here a case of a peripheral ameloblastoma associated with CEOT is presented with clinical and morphological features.
Clinical, radiological and histological features of calcifying epithelial odontogenic tumor: case report
Deboni, Maria Cristina Zindel;Naclério-Homem, Maria da Gra?a;Pinto Junior, Décio Santos;Traina, Andréia Aparecida;Cavalcanti, Marcelo Gusm?o Paraíso;
Brazilian Dental Journal , 2006, DOI: 10.1590/S0103-64402006000200017
Abstract: the calcifying epithelial odontogenic tumor (ceot) is a rare benign odontogenic neoplasm that accounts for approximately 1% of all odontogenic tumors. its origin is controversial as well as its true malignant potential. a case of an advanced ceot associated with an impacted right second molar in the mandible of a young black female patient is presented. computed tomography imaging, radiographic and pathological findings, surgical patterns, gross anatomy of the lesion and the performed treatment are discussed.
Intraosseous calcifying epithelial odontogenic tumor in a case with multiple myeloma  [cached]
Shanmuga Priya,Ravikumar A,Krishnarathnam K,Rajendiran S
Journal of Oral and Maxillofacial Pathology , 2009,
Abstract: Calcifying epithelial odontogenic tumor (CEOT), also known as Pindborg tumor, is a rare benign odontogenic tumor of locally aggressive behavior. It is more common in the posterior part of the mandible of adults, typically in the fourth to fifth decades. Its origin as well as its true malignant potential is not clearly known. It usually starts as a painless swelling and is often concurrent with an impacted tooth. A case of CEOT in a 55-year-old man with multiple myeloma is presented. Clinical, radiological, and pathologic findings are discussed.
Implantosuported Rehabilitation after Marginal Recession of Mandibular Calcifying Epithelial Odontogenic Tumor: Case Report  [PDF]
Bruna Barcelos Ferreira, Victor Tieghi Neto, Andréa Guedes Barreto Gon?ales, Denise Tostes Oliveira, Fábio Sanches Magalh?es Tunes, Eduardo Sanches Gon?ales
Open Journal of Stomatology (OJST) , 2019, DOI: 10.4236/ojst.2019.99021
Abstract: The Calcifying Epithelial Odontogenic Tumor (CEOT) also called the Pindborg’s Tumor represents a rare benign epithelial odontogenic neoplasm with locally aggressive behavior. Surgical excision with a safety margin is one of the treatment options, requiring bone and soft tissue reconstruction for implant-supported rehabilitation, providing the individual with a return to adequate oral functions. The objective of the present study is to report on the case of the treatment stages and the factors involved in the rehabilitation of a 23-year-old man with a history of mandibular lesion diagnosed as CEOT. A marginal resection of the mandible lesion was performed, with posterior reconstruction with iliac crest bone graft and soft tissue graft to allow the implant-supported rehabilitation. Currently, in the postoperative control, the individual shows no signs of tumor recurrence and is rehabilitated without functional and/or aesthetic complaints. Surgical excision should be framed as a form of treatment, aiming for better resolution in the more complex cases of these invasive tumors.
Calcifying cystic odontogenic tumor- a unique developmental lesion arising in mandible  [PDF]
S Vasudev,VP Singh,R Jhawar,DK Roy
Health Renaissance , 2012, DOI: 10.3126/hren.v10i1.6012
Abstract: Calcifying cystic odontogenic tumor (CCOT) is a unique developmental lesion arising from the odontogenic epithelial remnants present in the jaw bones. It is a very rare lesion having a distinctive histopathologic appearance characterized by the presence of ghost cells with considerable amount of histopathologic diversity. The case report describes a rare and unusually large presentation of CCOT in an 18 year old female. The patient presented with a large swelling in the mandibular’ anterior region. After clinical, radiographic investigations, an incisional biopsy was performed and a diagnosis of CCOT was made. The cyst was enucleated with complete removal of cystic lining. The patient has recovered well and has been kept under observation. DOI: http://dx.doi.org/10.3126/hren.v10i1.6012 HREN 2012; 10(1): 64-68
Tumor de Pindborg (tumor odontogénico epitelial calcificante) Pindborg tumor (Calcifying epithelial odontogenic tumor)  [cached]
J. Rubio Palau,C. Bescós Atín,J. Pamias Romero,M. Sáez Barba
Revista Espa?ola de Cirugía Oral y Maxilofacial , 2007,
Abstract: El objetivo del presente artículo es realizar una revisión de la literatura del tumor de Pindborg a propósito de un caso. El interés radica en su baja frecuencia y a la importancia de la anatomía patológica para su diagnóstico y correcto tratamiento ya que puede confundirse en algunos casos con otras tumoraciones benignas, a diferencia de las cuales, en este tumor debe realizarse una resección con márgenes de seguridad para disminuir la probabilidad de recidiva. The aim of this article is to review the literature on Pindborg tumor based on a case. In view of its low frequency and the importance of histology for its correct diagnosis and treatment as it can be confused with other benign tumors, appropriate resection is necessary with tumor-free margins in order to reduce the probability of local recurrence.
Different manifestations of calcifying cystic odontogenic tumor  [PDF]
Estevam Rubens Utumi,Irineu Gregnanin Pedron,Leopoldo Penteado Nucci da Silva,Gustavo Grothe Machado
Einstein (S?o Paulo) , 2012,
Abstract: The calcifying cystic odontogenic tumor normally presents as apainless, slow-growing mass, involving both maxilla and mandible,primarily the anterior segment (incisor/canine area). It generallyaffects young adults in the third to fourth decades, with no genderpredilection. Computerized tomography images revealed importantcharacteristics that were not detected by panoramic radiography,such as fenestration, calcification and tooth-like structures. Thetypical microscopic feature of this lesion is the presence of variableamounts of aberrant epithelial cells, without nuclei, which arenamed “ghost cells”. In addition, dysplastic dentine can be foundand occasionally the cyst can be associated with an area of dentalhard tissue formation resembling an odontoma. The treatment forcalcifying cystic odontogenic tumor involves simple enucleationand curettage. The purpose of this article is to present two differentmanifestation of calcifying cystic odontogenic tumor in whichcomputerized tomography, associated to clinical features, servedas an important tool for diagnosis, adequate surgical planning andfollow-up of patients.
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