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Lower Extremity Cutaneous Lesions as the Initial Presentation of Metastatic Adenocarcinoma of the Colon
Dhyan Rajan,Mitanshu Shah,Pooja Raghavan,Shanza Mujeeb,Sadat Rashid,Aieska Desouza,Paul Mustacchia
Case Reports in Medicine , 2012, DOI: 10.1155/2012/989104
Abstract: Cutaneous metastases from colorectal cancers are rare and are usually present on the abdominal wall or previous surgical incision sites. Remote cutaneous lesions have been reported, however, often occur in the setting of widespread metastatic disease including other visceral secondaries. We present a case of lower extremity cutaneous metastases as the first sign of metastatic disease in a patient with adenocarcinoma of the colon. This case illustrates that new skin lesions may be the initial presentation of metastatic disease in a patient with a history of cancer.
Adenocarcinoma of the Rectum with Cutaneous Metastases  [cached]
Gamal Abdul Hamid,Nohad Hanbala
Middle East Journal of Cancer , 2012,
Abstract: Cutaneous metastases of rectal carcinoma is a rare event. It occurs in fewer than 4% of all patients with rectal cancer. When present, it typically signifies a disseminated disease with a poor prognosis. Early detection and proper diagnosis of metastatic rectal cancer can significantly alter treatment and prognosis. We report a 70-year-oldmale who underwent rectal resection with permanent colostomy for rectal adenocarcinoma since seven years. The patient recently developed multiple skin nodules, mainly in his face, scalp, and upper trunk, associated with itching. Fine needle aspiration cytology from a face nodule was done which revealed metastatic adenocarcinoma associated with severe inflammation. Cutaneous metastasis of rectaladenocarcinoma is an unusual event that presents mainly in the form of skin nodules and could be the first sign of metastasis. Early diagnosis of cutaneous metastasis in these patients is important because it can alter treatment and prognosis.
Metastatic cutaneous adenocarcinoma
Thami Gurvinder,Sharma Ramesh,Sharma Nand,Sharma Ashok
Indian Journal of Dermatology, Venereology and Leprology , 1997,
Metastatic cutaneous adenocarcinoma
Thami Gurvinder,Sharma Ramesh,Sharma Nand,Sharma Ashok
Indian Journal of Dermatology, Venereology and Leprology , 1998,
Primary Cutaneous Low Grade Mucinous Adenocarcinoma of Eyelid  [cached]
Geethalakshmi U,Vijayshankar S,Abhishek MG,Indira CS
Online Journal of Health & Allied Sciences , 2010,
Abstract: Primary cutaneous mucinous adenocarcinoma is a rare adnexal neoplasm, eyelid being the most common site of presentation. Clinically it is mistaken for a benign / cystic lesion. Its morphologic similarity to metastatic deposits from breast, gastrointestinal tract (GIT) or any visceral sites adds to the diagnostic difficulty mandating the role of ancillary techniques in precise diagnosis and hence planning the management. We report a case of primary cutaneous mucinous adenocarcinoma of eyelid with emphasis on pathology along with a brief review of literature.
Choroidal and cutaneous metastasis from gastric adenocarcinoma  [cached]
Shoichiro Kawai,Tsutomu Nishida,Yoshito Hayashi,Hisao Ezaki
World Journal of Gastroenterology , 2013, DOI: 10.3748/wjg.v19.i9.1485
Abstract: Choroidal or cutaneous metastasis of gastric cancer is rare. Gastrointestinal cancer was found in only 4% in patients with uveal metastasis. Choroidal metastasis from gastric cancer was reported in two cases in earlier literature. The frequency of gastric cancer as a primary lesion was 6% in cutaneous metastasis of men, and cutaneous metastasis occurs in 0.8% of all gastric cancers. We report a patient with gastric adenocarcinoma who presented with visual disorder in his left eye and skin pain on his head as his initial symptoms. These symptoms were diagnosed to be caused by choroidal and cutaneous metastasis of gastric adenocarcinoma. Two cycles of chemotherapy consisted of oral S-1 and intravenous cisplatin (SPIRITS regimen); this was markedly effective to reduce the primary gastric lesion and almost all the metastatic lesions.
Dermatomyositis associated with metastatic rectal adenocarcinoma: Case report  [PDF]
Vesi? Sonja,?akovi? Zorana,Vuki?evi? Jelica,Vukovi? Jelena
Medicinski Pregled , 2009, DOI: 10.2298/mpns0910473v
Abstract: Introduction. Dermatomyositis is an idiopathic inflammatory myopathy with characteristic cutaneous changes. The disease belongs to paraneoplastic dermatosis. Association of dermatomyositis with malignant conditions has been described in various studies. We present a patient with paraneoplastic dermatomyositis associated with metastatic rectal adenocarcinoma. Case report. A 66 - year - old man was hospitalized in our Institute due to skin changes and myopathy in October 2006. According to the medical documents and history, he underwent surgery because of rectal adenocarcinoma in April 2006. Skin changes appeared 5 months before, while aggravation occurred 6 months after the surgery. The diagnosis of dermatomyositis was based on: characteristic clinical picture; the elevated serum level of following enzymes: creatinine kinase, lactate dehydrogenase; the presence of anti - Mi 2 antibodies in serum; electromyographic finding; and by histology of the muscle biopsy. Paraneoplastic nature of dermatomyositis was confirmed by computer tomography of the abdomen which revealed multiple deposits in the liver, by explorative laparotomy showing peritoneal dissemination and histopathological analysis that verified metastatic adenocarcinoma of the rectum. The oncological consulting team suggested chemotherapy which was not carried out because of the rapid lethal outcome. Conclusion. We report a case of paraneoplastic dermatomyositis associated with metastatic rectal adenocarcinoma and lethal outcome, and suggest a comprehensive evaluation of patients with dermatomyositis older than 50 years in order to exclude or verify the occult malignancy.
A rare cutaneous tumor of the axilla: Apocrine adenocarcinoma  [cached]
Karaca Semsettin,Kulac Mustafa,Sahin Onder,Esme Hidir
Indian Journal of Dermatology , 2007,
Abstract: Sweat gland neoplasms are rare with approximately 200 cases of eccrine sweat gland and less than 50 cases of apocrine gland carcinoma being reported in the worldwide literature. More than half of the reported cases with apocrine adenocarcinoma had lymph node metastases at the time of diagnosis. We report a case of a 56-year-old man, presented with a left axillary slow-growing seven year old painless nodule. Histopathological examination revealed an invasive apocrine adenocarcinoma with lymph node metastases. The patient successfully treated with total excision and radiotherapy. Apocrine adenocarcinoma is a rare malignancy with high metastatic potential that occurs mostly in the axilla. Physicians should be aware of this entity while differentiating cutaneous tumor located on the axillary region.
Gastric Adenocarcinoma Deposits Presenting as Multiple Cutaneous Nodules: A Case Report with Review of Literature
Türk Patoloji Dergisi , 2012,
Abstract: Metastases to the skin from internal tumors are uncommon, yet they may be the first presentation of such malignancies. They usually arise from the breast, lung and large bowel. Cutaneous metastases from gastric adenocarcinoma are extremely rare. We report a case of gastric adenocarcinoma that at presentation had multiple clinically benign looking skin nodules. Fine needle aspiration cytology of the cutaneous nodule revealed metastatic deposits. The current literature on cutaneous metastases of gastric carcinoma is reviewed in this case report.
Cutaneous metastases from colonic adenocarcinoma: case report
Gomes, Caroline Merci Caliari de Neves;Bin, Fang Chia;Klug, Wilmar Artur;Valois, Tiago;Preza, Marilia Tassinari Gon?alves;
Journal of Coloproctology (Rio de Janeiro) , 2012, DOI: 10.1590/S2237-93632012000300013
Abstract: the presence of cutaneous metastases (cm) from a digestive tract cancer is infrequent, appearing in less than 5% of the cases. given the low incidence of metastasis from colon adenocarcinoma, an unusual case that occurred in the colorectal surgery department of santa casa de s?o paulo is described in this report, and a brief review of literature is presented. a 78-year-old female patient who underwent right hemicolectomy, developed a tumor with approximately 8 cm in diameter in her gluteus eight months later, which was surgically resected, and the histological diagnosis was metastatic adenocarcinoma of the right colon. although the literature estimated short survival in cases of cm, the patient developed no signs of tumor recurrence five months after the onset of metastasis in the gluteus, with significant improvement in her quality of life.
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