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Hepatitis viral aguda
Hernández Garcés,Héctor Rubén; Espinosa álvarez,René F.;
Revista Cubana de Medicina General Integral , 1998,
Abstract: a bibliographical review of acute viral hepatitis was made taking into account those aspects connected with its etiology. some epidemiological markers, the most important clinical forms, and the complementary examinations with special emphasis on the viral markers and the positive diagnosis were also considered
Hepatitis viral aguda
Héctor Rubén Hernández Garcés,René F. Espinosa álvarez
Revista Cubana de Medicina General Integral , 1998,
Abstract: Se realizó una revisión bibliográfica de las hepatitis virales agudas sobre aspectos vinculados a su etiología. Se tuvieron en cuenta además algunos datos epidemiológicos, las formas clínicas más importantes, los exámenes complementarios con especial énfasis en los marcadores virales y el diagnóstico positivo A bibliographical review of acute viral hepatitis was made taking into account those aspects connected with its etiology. Some epidemiological markers, the most important clinical forms, and the complementary examinations with special emphasis on the viral markers and the positive diagnosis were also considered
The Professional Medical Journal , 2002,
Abstract: OBJECTIVE: To evaluate the prevalence of hepatitis viruses, presented with acute hepatitis (AH) at LiaquatUniversity Hospital Hyderabad / Jamshoro. DESIGN: Hospital based descriptive of 100 individuals. PLACE&DURATION: This study was conducted in the medical wards of Liaquat University of Medical and Health SciencesHospital from January, 2000 to July, 2001. MATERIAL &METHODS: A total sera of 100 patients admitted withacute hepatitis were investigated to determine the cause. Serum samples were tested for anti-HAV, HBsAg, anti-HBs andanti-HBc, anti-HCV, anti-HEV and HGV RNA. RESULTS: Results showed that eight (8%) individuals werescreened as hepatitis A and four (4%) had HAV/HBV co-infection. Thirty nine (39%) had hepatitis B and hepatitis Dsuper infection amongst HBsAg positive was found in two (2%) of individuals. Antibody to HCV was detected in nine(9%) individuals, three with HBV and two with HEV infection, while rest of the four were exclusively infected withHCV. Fourteen (14%) individuals probably with hepatitis E, five of whom had evidence of antecedent HBV infection.Five (5%) individuals were screened as HGV, two of these were found to have co-infection with HCV, another two ofthem were found to have mixed infection with hepatitis B and C viruses. The viral hepatitis markers were all negative innineteen (19%) of the total individuals. CONCLUSION: Our data demonstrate a strong background of HBV infectionsrising concern about its chronic sequelae in this part of country. Because HBV infection is highly endemic in Sindh, wepropose that the community based mass immunization must be conducted as soon as possible particularly in this area ofSindh.
Hepatitis viral tipo A
Rosario García,Georgina Carrada,Clara M. Martínez
Salud en Tabasco , 2001,
Abstract: La hepatitis viral tipo A (HVA) constituye un importante problema de salud pública a nivel mundial. Esta enfermedad producida por el virus de la hepatitis A, puede generar un cuadro clínico de instalación súbita o pasar inadvertida. Para la semana 38 de 1999, en México existían 13,123 casos acumulados de HVA. Ese mismo a o se realizó un estudio en 12,000 sujetos de 6 países latinoamericanos para determinar la seroprevalencia de hepatitis A, ocupando México el 2o lugar (81.0%), precedido sólo por República Dominicana (89.0%). Como profilaxis preexposición se han desarrollado vacunas inactivadas y atenuadas contra la hepatitis A. La gammaglobulina se utiliza como profilaxis post exposición; sin embargo, la administración masiva de inmunoglobulina no sustituye las medidas ambientales.
Hepatitis aguda viral durante el embarazo
Valdés R,Enrique; Sepúlveda M,Alvaro; Candia P,Paula; Lattes A,Karina;
Revista chilena de infectología , 2010, DOI: 10.4067/S0716-10182010000700003
Abstract: acute hepatitis has a very low incidence disease during pregnancy. however, it may be an important cause of jaundice during gestation which in cases of viral etiology can have a very high morbidity and mortality risk to the mother and the fetus. the purpose of this review is to update the available knowledge regarding viral hepatitis during pregnancy including description of the main etiologies, transmission route, maternal-fetal risk and possible management.
Antibody Responses during Hepatitis B Viral Infection  [PDF]
Stanca M. Ciupe ,Ruy M. Ribeiro,Alan S. Perelson
PLOS Computational Biology , 2014, DOI: doi/10.1371/journal.pcbi.1003730
Abstract: Hepatitis B is a DNA virus that infects liver cells and can cause both acute and chronic disease. It is believed that both viral and host factors are responsible for determining whether the infection is cleared or becomes chronic. Here we investigate the mechanism of protection by developing a mathematical model of the antibody response following hepatitis B virus (HBV) infection. We fitted the model to data from seven infected adults identified during acute infection and determined the ability of the virus to escape neutralization through overproduction of non-infectious subviral particles, which have HBs proteins on their surface, but do not contain nucleocapsid protein and viral nucleic acids. We showed that viral clearance can be achieved for high anti-HBV antibody levels, as in vaccinated individuals, when: (1) the rate of synthesis of hepatitis B subviral particles is slow; (2) the rate of synthesis of hepatitis B subviral particles is high but either anti-HBV antibody production is fast, the antibody affinity is high, or the levels of pre-existent HBV-specific antibody at the time of infection are high, as could be attained by vaccination. We further showed that viral clearance can be achieved for low equilibrium anti-HBV antibody levels, as in unvaccinated individuals, when a strong cellular immune response controls early infection.
Acute viral E hepatitis with chronic liver disease (Autoimmune hepatitis)  [cached]
Desai H,Naik A
Indian Journal of Medical Sciences , 2005,
Abstract: A 36 years old male presented with anorexia, jaundice and ascites. He was suffering from acute viral E hepatitis. In view of ascites, he was investigated for associated asymptomatic chronic liver disease (CLD). The CLD was diagnosed as cirrhosis with autoimmune hepatitis and was treated with steroid with good response. He is maintaining good health with low dose steroid, on follow up for 1 year.
Experience with Hepatitis B viral load testing in Nigeria
AP Okwuraiwe, OB Salu, CK Onwuamah, OS Amoo, NN Odunukwe, RA Audu
African Journal of Clinical and Experimental Microbiology , 2011,
Abstract: Background: Quantification of the viral burden is an important laboratory tool in the management of hepatitis B virus (HBV)-infected patients. However, widespread use of assays is still hampered by the high cost. Treatment reduces viral load to undetectable levels. HBV infected patients tend to have high HBV DNA levels, and severe liver disease. Objectives: This study was carried out to determine the pattern of HBV viral load levels of patients assessing management in Nigeria. Method: Variables included sociodemographics like age, sex, religion, income, educational background and residence. The COBAS Amplicor automated Analyzer (PCR based) was used to assay the virus quantitatively. Results: 594 patients were tested from 2008 to 2009. Statistical analysis was done using Epi info version 2002 and test of significance by Kruskal-Wallis. Mean age of the patients was 36.8 (ranging from 9 to 69) years. HBV viral titre ranged between 4,145 and 68,011,800 DNA copies/ml. Conclusion: There was a high occurrence of viral titre in the population studied. High viral load is a risk factor for hepatocellular carcinoma. A policy earmarked to combat this virus in Nigeria is hereby solicited.
Clinical study of hepatitis in children with special reference to viral markers.  [PDF]
Zankhana Parekh,Rohit Modi,Deepa Banker,Pallavi Dagali
NHL Journal of Medical Sciences , 2013,
Abstract: nfective hepatitis is a systemic viral infection marked by hepatic cell necrosis and hepatic inflammation which leads to a characteristic constellation of clinical, biochemical and histological changes. This exercise was done to study the epidemiology of infective hepatitis, presenting symptoms and signs, mode of transmission, complication and outcome and to study the role of various investigations with special focus on viral markers. We concluded that poor outcome related with viral hepatitis in children were HBsAg reactivity, higher SGPT and serum bilirubin levels, higher PT levels and development of encephalopathy. Anti HAV and anti HEV IgM markers are very sensitive test for diagnosing acute infection.
El control de la hepatitis viral A en instituciones cerradas
Berdasquera Corcho,Denis;
Revista Cubana de Medicina General Integral , 2002,
Abstract: in spite of the sanitation improvement in many countries, viral hepatitis a remains a health problem that occurs in the form of outbreaks which very frequently affect enclosed institutions such as day-care centers, kindergartens, boarding schools, camps, and military barracks, among others. this article makes a documentary review on the topic and summarizes the main measures that the primary health care personnel should take to control viral hepatitis a foci in enclosed institutions.
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