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Vaccine against Dental Caries: An Update  [PDF]
Diego Romário da Silva, Andréa Cristina Barbosa da Silva, Robeci Macedo Filho, Flaviana Dornela Verli, Sandra Aparecida Marinho
Advances in Microbiology (AiM) , 2014, DOI: 10.4236/aim.2014.413103

Dental caries, the disease that causes tooth decay, is infectious, and the mutans streptococci bacteria have long been identified as the primary disease-causing agents. Caries vaccines showed promising results in experimental studies; however, it remains far the effective use in humans due to political-economic and ethical issues. Progress towards practical vaccine development requires evaluation of candidate vaccines in clinical trials. Promising strategies of passive immunization also require further clinical evaluation. The purpose of this chapter is to review the literature on the main research projects aimed at developing caries vaccines.

Incidence of dental caries in chronic urticaria
Kaur Surrinder,Ghosh Srabani,Kanwar A,Gauba A
Indian Journal of Dermatology, Venereology and Leprology , 1991,
Abstract: Three hundred patients of chronic urticaria were screened for dental affections. Sixty two (20.66%) patients were detected to have dental caries. Among the control group which com-prised of 100 patients, 20% had dental caries. There was thus no increased incidence of dental caries among patients with urticaria. Only 2 patients had remission of urticaria following treat-ment of caries. Dental caries therefore is probably not a cause of chronic urticaria.
Early prevention of dental caries in children  [PDF]
Kharitonova T.L.,Lebedeva S.N.,Kazakova L.N.
Saratov Journal of Medical Scientific Research , 2011,
Abstract: Early prevention of dental caries in children plays an important role in the preservation of dental health. This article explains the necessity of early prevention of dental caries in children. The most effective methods of prevention of dental caries are beginning hygiene care and respect for the recommendations dentist since the first teeth. It is shown that the use of conservative therapy is very effective in the treatment of early forms of dental caries
Health promotion and dental caries
Maltz, Marisa;Jardim, Juliana Jobim;Alves, Luana Severo;
Brazilian Oral Research , 2010, DOI: 10.1590/S1806-83242010000500004
Abstract: the central idea of the brazilian health system is to prevent the establishment of disease or detect it as early as possible. prevention and treatment of dental caries are related to behavioral factors, including dietary and oral hygiene habits, which are related to many chronic diseases. dental health promotion therefore should be fully integrated into broadly based health-promoting strategies and actions such as food and health policies, and general hygiene (including oral hygiene), among others. for decades, a linear relationship between sugar consumption and caries has been observed. recent data has indicated that this relationship is not as strong as it used to be before the widespread use of fluoride. however, diet is still a key factor acting in the carious process. oral hygiene is a major aspect when it comes to caries, since dental biofilm is its etiological factor. oral hygiene procedures are effective in controlling dental caries, especially if plaque removal is performed adequately and associated with fluoride. an alternative to a more efficient biofilm control in occlusal areas is the use of dental sealants, which are only indicated for caries-active individuals. if a cavity is formed as a consequence of the metabolic activity of the biofilm, a restorative material or a sealant can be placed to block access of the biofilm to the oral environment in order to prevent caries progress. the prevention of dental caries based on common risk-factor strategies (diet and hygiene) should be supplemented by more disease-specific policies such as rational use of fluoride, and evidence-based dental health care.
Dental caries: Therapeutic possibilities  [PDF]
Peri? Tamara,Markovi? Dejan,?ivkovi? Slavoljub
Srpski Arhiv za Celokupno Lekarstvo , 2008, DOI: 10.2298/sarh0812662p
Abstract: Contemporary tendencies in dentistry are based on the concept of maximal protection of healthy tooth tissues. Caries removal has been done traditionally with mechanical rotary instruments that are fast and precise. However, conventional cavity preparation has potential adverse effects to the pulp due to heat, pressure and vibrations. Moreover, drilling often causes pain and requires local anaesthesia, and these procedures are frequently perceived as unpleasant. Etiology, development and prevention of dental caries are better understood today and new restorative materials that bond micromechanically and/or chemically to dental tissues have been introduced. Thus, development of a new, less destructive caries removal technique is allowed. In the last decades, many alternative methods have been introduced in an attempt to replace rotary instruments. These are claimed to be efficient and selective for diseased tissues and to offer comfortable treatment to the patients. New methods include air abrasion, air polishing, ultrasonic, polymer burs, enzymes, systems for chemo-mechanical caries removal, and lasers. The aim of this paper was to discuss various caries removal techniques and possibilities of their use in clinical practice. Based on the literature review it can be concluded that none of the new caries removal methods can completely replace conventional rotary instruments.
Asthma: A Risk Factor for Dental Caries?  [PDF]
MS Thomas,A Parolia,M Kundabala
Journal of Nepal Paediatric Society , 2010, DOI: 10.3126/jnps.v30i3.3929
Abstract: This report points out a correlation between asthma and dental caries. It also gives certain guidelines on the measures to be taken in an asthmatic to negate the risk of dental caries. Key words: Asthma, Caries risk, Caries prevention, Dental caries DOI: 10.3126/jnps.v30i3.3929 J Nep Paedtr Soc 2010;30(3):175-176
Gaurav Solanki
International Journal of Biomedical and Advance Research , 2012, DOI: 10.7439/ijbar.v3i2.353
Abstract: Dental caries called as tooth decay is basically a disease in which bacterial processes changes carbohydrate to acid. This acid then dematerializes the hard tooth structure. They are produced when demineralization amount exceeds the remineralization amount. Streptococcus mutans and Lactobacillus are the bacteria responsible for the dental caries. This article throws light on the dental caries disease, its sign and symptoms, treatment, prevention and risk factors associated with it. A review of some patents on dental caries is also provided that summarizes the recent technical advancements taken place in this area.
Bioquímica de la caries dental Biochemistry of dental caries
Daniel Pedro Nú?ez,Lourdes García Bacallao
Revista Habanera de Ciencias M??dicas , 2010,
Abstract: La caries dental constituye una de las enfermedades crónicas y transmisibles que con mayor frecuencia afecta a los seres humanos, por lo que es objeto de estudio de numerosos investigadores con el propósito de lograr su prevención y tratamiento. En el siguiente trabajo, realizamos una revisión bibliográfica con el objetivo de profundizar en los conocimientos teóricos acerca de la caries dental describiendo los factores y mecanismos que propician la aparición de esta patología, así como los mecanismos de acción de los fluoruros, los edulcorantes, los agentes antibacterianos y el ozono. The dental caries constitutes one of the chronic and transferable illnesses that affects the human beings with more frequency, for what is object of numerous investigators' study with the purpose of achieving its prevention and treatment. In the following work we carry out a bibliographical revision with the objective of deepening in the theoretical knowledge about the dental caries describing the actors and mechanisms that propitiate the appearance of this pathology, as well as the mechanisms of action of the fluorides, antibacterial agents, the edulcorating and the ozone
Detection of oral streptococci in dental biofilm from caries-active and caries-free children
Silva, Andréa Cristina Barbosa da;Cruz, Jader dos Santos;Sampaio, Fábio Correia;Araújo, Demetrius Ant?nio Machado de;
Brazilian Journal of Microbiology , 2008, DOI: 10.1590/S1517-83822008000400009
Abstract: this work correlated the presence of oral streptococci in dental biofilm with clinical indexes of caries and oral hygiene in caries-active and caries-free children. s. mutans and/or s. sobrinus in the dental biofilm does not indicate a direct risk for developing dental caries.
Epidemiology of dental caries: when structure and context matter  [cached]
Paulo Fraz?o
Brazilian Oral Research , 2012, DOI: 10.1590/s1806-83242012000700016
Abstract: The widespread expansion of the sugar market drove dental caries prevalence to high levels in several regions of the world. On the other hand, the dissemination of fluoride use is one of the reasons for caries decline at the end of the 20th century. However, caries remains one of the most prevalent non-communicable chronic diseases in human beings, and an important cause of pain and dental loss, which lead to school and work absenteeism affecting individuals' daily activities and emotional stability. The decline in caries has important implications for research, human resources and oral healthcare. The aim of this study was to summarize the changes in dental caries occurrence in the population, and bring to light the latest research on the role of non-biological determinants in caries distribution.
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