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Universality of interpersonal psychotherapy (IPT) problem areas in Thai depressed patients
Peeraphon Lueboonthavatchai, Nuntika Thavichachart
BMC Psychiatry , 2010, DOI: 10.1186/1471-244x-10-87
Abstract: The Thai Hamilton Rating Scale for Depression (Thai HRSD) and Thai Interpersonal Questionnaire were used to assess 90 depressed and 90 non-depressed subjects in King Chulalongkorn Memorial Hospital, during July 2007 - January 2008. The association between interpersonal problem areas/sociodemographic variables and depressive disorder were analyzed by chi-square test. A multivariable analysis was performed by using logistic regression to identify the remaining factors associated with depressive disorder.Most of the subjects were young to middle-aged females living in Bangkok and the Central Provinces. All four interpersonal problem areas (grief, interpersonal role disputes, role transitions, and interpersonal deficits) were increased in the depressed subjects as compared to the non-depressed subjects, as were the sociodemographic variables (low education, unemployment, low income, and having a physical illness). Logistic regression showed that all interpersonal problem areas still remained problems associated with depression (grief: adjusted OR = 6.01, 95%CI = 1.93 - 18.69, p < 0.01; interpersonal role disputes: adjusted OR = 6.01, 95%CI = 2.18 - 16.52, p < 0.01; role transitions: adjusted OR = 26.30, 95%CI = 7.84 - 88.25, p < 0.01; and interpersonal deficits: adjusted OR = 2.92, 95%CI = 1.12 - 7.60, p < 0.05).All four interpersonal problem areas were applicable to Thai depressed patients.Depressive disorder was one of the leading causes of worldwide disease burden, accounting for 4.46% of total disability-adjusted life-years (DALYs), and for 12.1% of total years lived with disabilities (YLDs) in 2000 [1]. Both major depressive disorder and dysthymic disorder are common depressive disorders, with a lifetime prevalence of about 15% and 3 - 6% respectively [2,3]. In Thailand, the lifetime prevalence of depressive disorder is about 5.7-20.9% [4]. Depressive disorder is believed to be caused by both biological and psychosocial factors.Interpersonal psychotherapy (IPT), de
Adaptation and Testing of Interpersonal Psychotherapy for Military Spouses
Helen Verdeli,Eleni Vousoura,Charles Baily,Alexander Belser
Journal of Educational and Developmental Psychology , 2011, DOI: 10.5539/jedp.v1n1p118
Abstract: The psychological impact of current military operations on service members deployed to Iraq and Afghanistan is well established. A number of recent studies have also demonstrated high rates of mental health difficulties, especially depression and anxiety, in spouses of deployed service members. This paper describes the adaptation of interpersonal psychotherapy (IPT), an evidence-based treatment for depression, to target depression in military spouses. The principles of IPT are outlined, and the ways in which the structure and content of the treatment lend themselves to the military context are described. Finally, a study currently underway to adapt and evaluate the treatment is presented and aspects of the treatment are illustrated.
Psicoterapia interpersonal en el tratamiento de la depresión mayor Interpersonal Psychotherapy in the Treatment of Major Depressive Disorder
Andrés Heerlein
Revista Chilena de Neuro-Psiquiatría , 2002,
Abstract: Introducction. Interpersonal psychotherapy (IPT), a time-limited psychotherapy, was developed in the 1970s as a treatment for outpatient adults with major depression. It has been subsequently modified for different age groups and types of mood and non mood disorders and for use as a long-term treatment. It has grown since in its range of research applications and in its clinical accessibility. Method. Review of recent research and educational developments on IPT. Results. IPT has demonstrated efficacy in several randomized controlled trials for acute major depression, for other psychiatric conditions and for long-term treatment of depression. Conclusions. By enhancing interpersonal functioning of the depressed patient IPT initiates the reduction of depressive symptomatology and helps solving current life problems as dual goal of therapy. The publication of efficacy data and the appearance of two North American practice guidelines that include IPT among validated treatments for depression have increased the interest among clinicians in many countries
Antidepressants versus interpersonal psychotherapy in treating depression in HIV positive patients
MYH Moosa, FY Jeenah
South African Journal of Psychiatry , 2012,
Abstract: Aim. Despite the prevalence of HIV and AIDS in South Africa reaching pandemic proportions, very few studies have been published on co-morbid depression. This study at Chris Hani Baragwanath Hospital was conducted on a group of HIV-positive patients with depression who were receiving antiretroviral treatment. The aim of the study was to describe their response to treatment with either an antidepressant or psychotherapy. Method. The study was prospective, randomised and controlled. The sampling was a convenience sampling, as it included patients attending the HIV clinic. At entry to the study, a clinical diagnostic evaluation and the Hamilton Depression Rating Scale (HAMD) were performed on all subjects by the investigator. The depressed patients were randomly assigned to receive either an antidepressant (citalopram) or psychotherapy (interpersonal psychotherapy, IPT). The HAMD was repeated at the study endpoint of 8 weeks. Results. Sixty-two HIV-positive persons receiving antiretrovirals participated in this study. Thirty of them were not depressed and served as controls, and 32 were depressed. There were no significant differences between the controls and the patients (either receiving pharmacotherapy or psychotherapy) in respect of any of the socio-demographic characteristics evaluated (p>0.05). Approximately 60% (n=19) of the depressed patients were, randomised to receive pharmacotherapy, while 40.6% (n=13) received IPT. The mean HAMD scores of the patients on pharmacotherapy decreased from 25.7 to 6.2 from entry to completion of the study, and those for patients receiving psychotherapy decreased from 22.5 to 8.2. The decreases in HAMD scores in patient groups receiving either pharmacotherapy or psychotherapy were not significantly associated with any socio-demographic variables (p>0.05). Conclusion. Both pharmacotherapy and psychotherapy may be equally effective in the treatment of depression in HIV-positive patients. The choice of treatment will be influenced by factors such as adverse effects of antidepressants and adding another medication to an already complex antiretroviral regimen. In such cases, IPT may be particularly beneficial.
Interpersonal Psychotherapy in the Treatment of Perinatal Depression  [PDF]
Gamze Ergil Altin
Psikiyatride Guncel Yaklasimlar , 2012,
Abstract: Perinatal depression is a psychiatric disorder that is not sufficiently diagnosed and directed to treatment. Its acute and chronic outcomes influence not only the mother but also the infant and the relationship between them. Both pregnancy and the postpartum periods are the times of significant physiological and emotional changes which also influence interpersonal relationships. Interpersonal risk factors like insufficient social support and increased social conflict can have an important impact on the women’s mental and physiological health during this period. Studies have shown that women prefer psychological and social management over drugs during this period. Interpersonal psychotherapy is a time-limited treatment approach, especially focusing on interpersonal difficulties with the goal of reducing depressive symptoms and improving interpersonal functioning. Such distressing factors which can occur during pregnancy and delivery are compatible with the four main problem areas that interpersonal psychotherapy addresses so that the therapist can easily use interpersonal psychotherapy in order to solve such difficulties.
The Development of Interpersonal Psychotherapy
人际心理治疗的发展

Xu Haiyan,Huang Xiting,
许海燕
,黄希庭

心理科学进展 , 2007,
Abstract: Interpersonal psychotherapy is a time-limited, manual-and-life-event based, diagnosis-targeted, and empirically tested treatment, which was originally developed for adult out-patients diagnosed with major depression and now for many sorts of disorders. There are some changes in its therapy process, including whether or not to give patients a"sick role", what to include in its problem areas, and how to deal with its termination and arrange time. Besides, this article provides a few process studies, analyses its briefness and integration with other psychotherapeutic factors and at last offers a discussion of features and problems of interpersonal psychotherapy's development.
Psicoterapia interpersonal en el tratamiento de la depresión mayor
Heerlein,Andrés;
Revista chilena de neuro-psiquiatría , 2002, DOI: 10.4067/S0717-92272002000500005
Abstract: introducction. interpersonal psychotherapy (ipt), a time-limited psychotherapy, was developed in the 1970s as a treatment for outpatient adults with major depression. it has been subsequently modified for different age groups and types of mood and non mood disorders and for use as a long-term treatment. it has grown since in its range of research applications and in its clinical accessibility. method. review of recent research and educational developments on ipt. results. ipt has demonstrated efficacy in several randomized controlled trials for acute major depression, for other psychiatric conditions and for long-term treatment of depression. conclusions. by enhancing interpersonal functioning of the depressed patient ipt initiates the reduction of depressive symptomatology and helps solving current life problems as dual goal of therapy. the publication of efficacy data and the appearance of two north american practice guidelines that include ipt among validated treatments for depression have increased the interest among clinicians in many countries
The Biological Effects of Psychotherapy in Major Depressive Disorders: A Review of Neuroimaging Studies  [PDF]
Gülfizar S?zeri-Varma, Filiz Karada?
Psychology (PSYCH) , 2012, DOI: 10.4236/psych.2012.310129
Abstract: Major depressive disorder (MDD) is a syndrome, which is quite frequent in the society, can be recurrent and shows symptoms of emotional, cognitive and behavioral disorder. Brain imaging studies support that patients diagnosed with MDD suffer dysfunction in limbic structures such as frontal cortex, amygdala, hippocampus and cingulate cortex and basal ganglions that regulate these functions. Psychotherapy is an effective treatment option for prevention of recurrent depressive attacks as well as for acute treatment of depression. It is thought that psychotherapy shows its effect by focusing on misleading cognitions and emotional information processing processes that lead to rise and persistence of symptoms of depression, which in turn boosts problem solving and coping skills. Neurobiological reflections of clinical recovery achieved by psychotherapy are not yet well known. In this study, it is aimed to review cognitive behavioral psychotherapy (CBT), interpersonal psychotherapy (IPT) and psychodynamic psychotherapy methods used frequently in treatment of MDD, along with functional brain imaging studies performed on treated depressive patients. Studies show that CBT lead to changes in the prefrontal cortex, cingulate cor- tex and amygdala metabolisms and activities. Activity of the subgenual cingulate cortex, which takes part in the regulation of the limbic activity, seems to play an important role in the response to CBT like in the response to antidepressant treatment. It was found that interpersonal psychotherapy (IPT) ensures recovery of metabolism and blood flow in the prefrontal cortex, cingulate cortex and basal ganglions. It was observed that psychodynamic therapy ensured recovery of abnormal activities in especially the prefrontal cortex and cingulate cortex in MDD, similar to the CBT and IPT. There is need for more long-term, follow-up studies in this area.
The effectiveness of individual interpersonal psychotherapy as a treatment for major depressive disorder in adult outpatients: a systematic review
Madelon L J M van Hees, Thomas Rotter, Tim Ellermann, Silvia M A A Evers
BMC Psychiatry , 2013, DOI: 10.1186/1471-244x-13-22
Abstract: Systematic searches of PubMed and PsycINFO studies between January 1970 and August 2012 were performed to identify (C-)RCTs, in which MDD was a primary diagnosis in adult outpatients receiving individual IPT as a monotherapy compared to other forms of psychotherapy and/or pharmacotherapy.1233 patients were included in eight eligible studies, out of which 854 completed treatment in outpatient facilities. IPT combined with nefazodone improved depressive symptoms significantly better than sole nefazodone, while undefined pharmacotherapy combined with clinical management improved symptoms better than sole IPT. IPT or imipramine hydrochloride with clinical management showed a better outcome than placebo with clinical management. Depressive symptoms were reduced more in CBASP (cognitive behavioral analysis system of psychotherapy) patients in comparison with IPT patients, while IPT reduced symptoms better than usual care and wait list condition.The differences between treatment effects are very small and often they are not significant. Psychotherapeutic treatments such as IPT and CBT, and/or pharmacotherapy are recommended as first-line treatments for depressed adult outpatients, without favoring one of them, although the individual preferences of patients should be taken into consideration in choosing a treatment.Major depressive disorder (MDD) is a mental disorder characterized by a depressed mood, diminished interest or pleasure, sleeping problems and tiredness, and negative thoughts [1]. The mean one-year-prevalence of depression in European inhabitants between 18 and 65?years old is 6.9% [2], and 16.2-16.6% of US adults develop a major depressive disorder [3,4]. Furthermore, depression causes a high burden worldwide, taking fourth place in a ranking of leading contributors to the burden of diseases in 2000. In 2020, it is estimated that depression will take second place in the ranking for all ages and sexes [5]. Moreover, depression is the leading cause of years of l
The Effect of Interpersonal Psychotherapy and other Psychodynamic Therapies versus ‘Treatment as Usual’ in Patients with Major Depressive Disorder  [PDF]
Janus Christian Jakobsen,Jane Lindschou Hansen,Erik Simonsen,Christian Gluud
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0019044
Abstract: Major depressive disorder afflicts an estimated 17% of individuals during their lifetimes at tremendous suffering and costs. Interpersonal psychotherapy and other psychodynamic therapies may be effective interventions for major depressive disorder, but the effects have only had limited assessment in systematic reviews.
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