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Histochemical Features of the Extracellular Matrix in Rattus rattus norvegicus Otic Ganglion
Chagas,M. A.; Babinski,M. A.; Abidu-Figueiredo,M.; Costa,W. S.;
International Journal of Morphology , 2006, DOI: 10.4067/S0717-95022006000100015
Abstract: the otic ganglion is a cranial component of the parasympathetic division of the autonomic nervous system (ans). similar to other parasympathetic ganglia, otic ganglion presents multipolar neurons that are completely surrounded by satellite cells and intercellular substance as well, which allow us to use this ganglion as a good experimental model for studying the relationship neuron / extracellular matrix. we have studied rat otic ganglion in 10 animals through light microscopy. after routine histological methods, 5 μm sections were obtained and coloured by gomori`s trichrome, periodic acid-schiff (pas), alcian blue ph 2.5 and ph1.0, acetylation + pas, acetylation + deacetylation + pas, acid hydrolysis + pas, phenylhydrazine + pas and thiosemicarbazide + pas. the presence of neutral glycoproteins was demonstrated by pas reactivity. pas inhibition following alcian blue staining in ph 2.5 and 1.0 showed the presence of a small quantity of acid glycoprotein. the extracellular matrix analysis showed the presence of neutral and acid glycoconjugates. these findings suggests a mutual interaction and a complex role in ganglionic physiology
C. M. Cortez,W. S. Costa,M. A. Babinski,M. A. Chagas
International Journal of Morphology , 2003,
Abstract: The present work investigates the corticoid action on the growth of the superior cervical ganglion of the rat and describes the cortisol effect during early stages of development. The study was based on morphometric and stereological analysis of the perikarya. Eight rats were treated intraperitoneally with cortisol (1mg/Kg/day) during 36 days. Treatment was initiated in the 8th day after birth and was withdrawn one day before the sacrifice. There was a significant difference (<=P0,05) for the neural mean diameter between the control group (16.78 ± 1.11mm) and treated animals (15.84 ±0.99mm). The decrease of perikarya neuronal diameter was also demonstrated by stereological methods. Morphometrical findings may suggest alterations in superior cervical ganglion neuronal activity in rats treated for long term with cortisol Se investigó la acción de corticoides en el crecimiento del ganglio cervical superior de rata y se describieron los efectos del cortisol durante las fases tempranas de desarrollo. El estudio se basó en los análisis morfométrico y estereológico del pericario. Fueron inyectadas intraperitonealmente 8 ratas con cortisol (1mg/Kg/día) durante 36 días. El tratamiento se comenzó en el día 8 después del nacimiento, finalizándose un día antes del sacrificio. Hubo una diferencia significativa (<=P0,05) en el promedio del diámetro neuronal entre el grupo control (16.78 ± 1.11 mm) y los animales tratados (15.84 ± 0.99 mm). La disminución del diámetro neuronal del pericario también fue demostrada a través de la estereología. Los hallazgos morfométricos pueden hacer pensar en alteraciones de la actividad neuronal del ganglio cervical superior, en ratas tratadas por un largo periodo con cortisol
Prevalencia de leptospiras en Rattus rattus y Rattus norvegicus en el Gran Buenos Aires, Argentina
Arango,Julia; Cittadino,Emilio; Agostini,Adela; Dorta de Mazzonelli,Gleyre; Alvarez,Carlos; Colusi,Magdalena; Koval,Ariel; Cabrera Britos,Alejandro; Kravetz,Fernando;
Ecolog?-a austral , 2001,
Abstract: positive isolation of leptospires prevalence is described in naturally infected rats in the "villa" la cava, san isidro, buenos aires province. monthly captures, each lasting three days, were performed from december 1995 until november 1996. species, sex and weight of rats captured were determined. the prevalence rates (leptospiras were isolated from kidneys) were 45.8% in rattus norvegicus and 18.1% in rattus rattus. the isolations corresponded to virulent strains of leptospira interrogans serogroup icterohaemorrhagiae. in rattus norvegicus there was not significant difference among prevalence rates according to sex or weight. the high and persistent prevalence is a risk for human and animals living in the studied area.
Identificación de Hantavirus Andes en Rattus norvegicus Identification of Andes Hantavirus in Rattus norvegicus  [cached]
J Fernández,E Villagra,V Yung,J Tognarelli
Archivos de medicina veterinaria , 2008,
Abstract: En Chile y Argentina la especie Oligoryzomys longicaudatus ha sido identificada como el principal reservorio para Virus Andes (ANDV). El objetivo de este trabajo es reportar la presencia del virus Andes en Rattus norvergicus, roedor urbano recolectado de un muestreo en San Diego del Cristo, comuna de Melipilla, Región Metropolitana. La presencia del virus Andes en Rattus norvegicus podría indicar la importancia de otros roedores como eventuales vectores virales. In Chile and Argentina Oligoryzomys longicaudatus has been identified as the main reservoir for Hantavirus Andes. The aim of this work was to report the presence of Hantavirus Andes in Rattus norvegicus, an urban rodent collected during sampling in San Diego del Cristo, Melipilla, Metropolitan Region. The existence of Hantavirus Andes in Rattus norvegicus could indicate the importance of other rodents as possible viral vectors.
Identificación de Hantavirus Andes en Rattus norvegicus
Fernández,J; Villagra,E; Yung,V; Tognarelli,J; Araya,P; Mora,J; Cattan,PE; Ramírez,E;
Archivos de medicina veterinaria , 2008, DOI: 10.4067/S0301-732X2008000300011
Abstract: in chile and argentina oligoryzomys longicaudatus has been identified as the main reservoir for hantavirus andes. the aim of this work was to report the presence of hantavirus andes in rattus norvegicus, an urban rodent collected during sampling in san diego del cristo, melipilla, metropolitan region. the existence of hantavirus andes in rattus norvegicus could indicate the importance of other rodents as possible viral vectors.
Digestive Peritoneum in Wistar Rat (Rattus norvegicus) Peritoneo del Aparato Digestivo de la Rata Wistar (Rattus norvegicus)
Richard M?ller,Noelia Vazquez,Diana Teliz,Virginia Méndez
International Journal of Morphology , 2013,
Abstract: The laboratory rat (Rattus norvegicus albinus) has been used as a model for medical, biological and molecular research, for a long time. It is an interesting fact that there are no detailed descriptions of the gross anatomy of the liver and its ways of fixation. The aim of this study is to define clearly and according to the Nomina Anatomica Veterinaria principles, the liver and its way of fixation in this species of laboratory mammal. Eighty-eight rats (Rattus norvegicus albinus) were used, with a weight between 250 and 450 g. They were dissected in fresh, after been euthanized by an overdose of thiopental sodium intraperitoneal. An incision from the xiphoid cartilage up to the pubic region was made and another on each costal arch toward dorsal. La rata de laboratorio (Rattus norvegicus albinus) ha sido usada como modelo para investigaciones médicas, biológicas y moleculares, desde hace mucho tiempo. Sin embargo, no existen descripciones detalladas del peritoneo digestivo de la rata wistar. El objetivo de este trabajo es definir en forma clara y acorde a los principios de la Nómina Anatómica Veterinaria el peritoneo en esta especie de mamífero de laboratorio. Se utilizaron ochenta y ocho ratas (Rattus norvegicus albinus) de entre 250 y 450 g. Fueron disecadas en fresco luego de ser eutanasiadas por sobredosis de tiopental sódico intraperitoneal. Se realizó una incisión paramediana que se extendía desde el cartílago xifoides del esternón hasta el pubis y otra sobre cada arco costal hacia dorsal.
González-Acu?a,Daniel; Venzal,José M.; Guglielmon,Alberto A.;
Gayana (Concepción) , 2003, DOI: 10.4067/S0717-65382003000100015
Abstract: a male rhipicephalus sanguineus was found on a rattus norvegicus in the city of chillán (chile). this is the first record on this host in chile. the hypothetical sanitary importance of the finding is discussed
Blood cholesterol levels of hypercholesterolemic rat (Rattus norvegicus) after VCO treatment
Nusantara Bioscience , 2009,
Abstract: Harini M, Astirin OP. 2009. Blood cholesterol levels of hypercholesterolemic rat (Rattus norvegicus) after VCO treatment. Nusantara Bioscience 1: 53-58. This study aims to determine treatment effect of VCO on blood cholesterol levels in hypercholesterolemic white rat (Rattus norvegicus L.). This study used 25 male rats of Wistar strain divided into five treatment groups, namely: control, simvastatin (1.3 mL/270 g BW), cholesterol (9:1 lard), VCO 1 (1 mL/270 g BW), and VCO 2 (1.3 mL/270 g BW). Treatment was given orally. Total cholesterol, LDL and HDL cholesterol levels were measured at day 1, day 14 and day 28. Cholesterol data (total cholesterol, LDL and HDL) were analyzed by Ancova and followed by contrast test at significance level of 5%.. The results showed that treatment of VCO at different doses significantly affected the decrease in blood total cholesterol, blood LDL levels, increasing blood HDL in hipercholesterolemic white rat.
Larval recovery of Toxocara canis in organs and tissues of experimentally infected Rattus norvegicus
Lescano, Susana Z;Queiroz, Maísa L;Chieffi, Pedro P;
Memórias do Instituto Oswaldo Cruz , 2004, DOI: 10.1590/S0074-02762004000600016
Abstract: the aim of this note was to record for the first time the recovery of toxocara canis larvae from tissues and organs of rattus norvegicus (berkenhout, 1769), wistar strain, until the 60th day after experimental infection. rats were orally infected with embryonated t. canis eggs, killed on days 3, 5, 8, 10, 15, 30, and 60 after inoculation and larvae were recovered from liver, lungs, kidneys, brain, and carcass after acid digestion, showing a pattern of migration similar of that previously observed in mice.
The effect of fluoride on the serum level of calcium in the rat (Rattus norvegicus)
Fo?ak M.,Haskovi? E.,Suljevi? D.
Archives of Biological Sciences , 2012, DOI: 10.2298/abs1204585f
Abstract: The effect of fluoride on the calcium level in serum was analyzed in the laboratory rat Rattus norvegicus. The control group consisted of 10, and the experimental group of 15 animals. In the experimental group, fluoride at a concentration of 3 mg/100 g body weight of rats was intramuscularly injected into the musculus gluteus maximus. The concentration of calcium was measured by the CPC method. The average serum calcium concentration was 2.46 mmol/l, with female rats having higher values of serum calcium than male rats. Fluoride caused the reduction of calcium concentration in serum (p<0.05); the reduction was significantly expressed in female rats (p<0.000).
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