oalib
Search Results: 1 - 10 of 100 matches for " "
All listed articles are free for downloading (OA Articles)
Page 1 /100
Display every page Item
Metastasectomía pulmonar: experiencia de once a?os
Armas Pérez,Bárbaro Agustín; Reyes Balseiro,IEvelio Salvador; García Rodríguez,Miguel Emilio; Rubino de la Rosa,Jorge; Dumenigo Arias,Oscar;
Revista Cubana de Cirug?-a , 2009,
Abstract: introduction. lung metastases are frequent both in primary epithelial tumors and mesenchymatous tumors due to the fact that the whole cardiac output passes through the minor circulation. the surgical indication is a problem of cost-benefit relationship, and it is conditioned among other aspects by the disease free interval, the general state of the patient, the number of metastases and the type of resection. the objective of this study was to present our experience and results with this treatment. methods. a descriptive cross-sectional retrospective study was conducted in 6 patients with lung metastasis treated at "amalia simoni" hospital in camaguey between 1997 and 2007. the variables analyzed were sex, age, histopathology and localization of the primary tumor, initial operation, time elapsed between the initial operation and metastasectomy, number of pre- and transoperative metastases, approach route, localization of the nodules, type of surgical resection and survival. results. average age was 56 years old and there was no difference as regards sex. the primary tumors depended on the digestive system in 3 patients. most of them were unique nodules and pulmonary lobectomy was the most used procedure. average survival was 13 months. no important morbidity was reported and there were no deaths in the series.
Resultados de la metastasectomía pulmonar por osteosarcoma en ni os (1985 a 2005) Results of lung metastasectomy due to osteosarcoma in children (1985-2005)
Juan Carlos Collado Otero,Carlos Alberto González Chica,Dagmar Paredes López,Jesús de los Santos Renó Céspedes
Revista Cubana de Cirugía , 2007,
Abstract: En Cuba la incidencia real de la metastasectomía pulmonar en ni os con diagnóstico anatomopatológico de osteosarcoma no es bien conocida. Describir los resultados de esta operación en los pacientes pediátricos operados en nuestro servicio en un período de 20 a os fue el objetivo de este trabajo. Fueron operados 19 pacientes del total de 145 atendidos, entre los cuales fueron los varones en edades cercanas a la adolescencia a quienes con mayor frecuencia se practicó la metastasectomía pulmonar. Hubo un predominio de metástasis única; el pulmón más afectado fue el derecho, y por tanto, fueron más frecuentes los abordajes sobre ese hemitórax. La toracotomía vertical axilar derecha (técnica de Bordonne) y la metastasectomía en cu a fueron las técnicas más utilizadas. Pudimos observar, mediante métodos estadísticos y tablas de Kaplan Meier para sobrevida libre de eventos y la sobrevida global, que hubo una diferencia significativa en cuanto a la distribución de los tiempos y una alta morbilidad y mortalidad a pesar de la metastasectomía. In Cuba the real incidence of lung metastasectomy in children with anatomopathological diagnosis of osteosarcoma is not well known. The objective of this paper was to describe the results of this surgical procedure in pediatric patients operated on in our service in a period of 20 years. 19 patients of the total of 145 that received attention underwent surgery. Lung mastectomy was more frequent among males near the adolescence. There was a predominance of unique metastasis; the right lung was the most affected and, therefore, the approaches on this hemithorax were more common. The right vertical axilary thoracotomy (Bordonne technique) and wedge metastasectomy were the most used techniques. It was possible to observe by statistical methods and Kaplan Meier’s tables for event-free survival and global survival, a significant difference in connection with the distribution of times and a high morbidity and mortality, in spite of metastasectomy.
Resistencia de Streptococcus pyogenes a los antibióticos: Experiencia de once a os en un hospital pediátrico de Buenos Aires Antimicrobial resistance in Streptococcus pyogenes: An eleven-year surveillance in a pediatric hospital from Buenos Aires
Horacio A. Lopardo,Claudia Hernández,Patricia Vidal
Acta bioqu?-mica cl?-nica latinoamericana , 2004,
Abstract: En 1989 era escasa la preocupación acerca de la resistencia de Streptococcus pyogenes a los antibióticos habida cuenta de su sensibilidad universal a la penicilina. No obstante, algunos brotes puntuales en Japón y Australia de cepas resistentes a macrólidos en las décadas anteriores impulsaron a comenzar con la vigilancia de la resistencia de S. pyogenes a los antibióticos, primero en este hospital y luego en forma multicéntrica junto a otros centros de todo el país. En este trabajo se presentan los resultados de esta vigilancia, realizada durante once a os (período 1989-2000). No se encontraron cepas resistentes ni con sensibilidad intermedia a penicilina en estreptococos del grupo A. Tampoco fue detectada resistencia a cloranfenicol ni a tetraciclina. La resistencia a eritromicina ascendió de un 0 - 2,0% a un 9,9% durante el período citado y ese aumento se debió principalmente a aislamientos que presentaban el fenotipo M (probable eflujo), algunos de los cuales demostraron poseer el genotipo mefA. En aislamientos de infecciones invasivas no se detectó resistencia a eritromicina. Al comparar la evolución de la resistencia a eritromicina entre 1990 y 2000 con el consumo nacional de macrólidos se pudo observar una tendencia similar a la publicada previamente por investigadores finlandeses. Provided its universal susceptibility to penicillin, there was little interest about antimicrobial resistance in Streptococcus pyogenes before 1989. However, the knowledge about some outbreaks of erythromycin-resistant streptococci in Japan and Australia prompted us to begin a surveillance in the hospital and then as multicentre studies involving all the country. The results of such eleven-year surveillance (1989-2000) are being presented. Penicillin-resistant or intermediately-penicillin-susceptible group A streptococci were not found. Resistance to cloramphenicol or tetracycline was not detected. Erythromycin resistance changed from 0 - 2.0% to 9.9% along this period. These rates were due to the increasing isolation of streptococci showing the M phenotype (probably active efflux), some of them showing the mefA genotype. Among isolates obtained from invasive infections erythromycin resistance was not found. Comparing the evolution of erythromycin resistance with the national consumption of macrolides, a similar trend as that published by finnish authors was appreciated.
Resultados y enfoque de la metastasectomía pulmonar en el Instituto Nacional de Oncología y Radiobiología de Cuba Results and approach of lung metastasectomy in the National Institute of Oncology and Radiobiology of Cuba  [cached]
Juan Carlos Collado Otero,Dagmar Paredes López,Deborah Danta Fundora
Revista Cubana de Cirugía , 2008,
Abstract: INTRODUCCIóN. El objetivo de esta presentación fue identificar los factores pronósticos relacionados con mayor supervivencia tras la metastasectomía pulmonar, para todo tipo de tumor primario, practicada en el Instituto Nacional de Oncología y Radiobiología de Cuba. MéTODOS. Se realizó un estudio ambispectivo, no aleatorizado. El universo de estudio estuvo integrado por pacientes con metástasis pulmonares de origen intra o extrapulmonar. RESULTADOS. En el análisis univariado resultaron indicadores positivos predictivos de mayor intervalo libre de enfermedad y supervivencia global a los 3 a os, el número (p = 0,004) y el tama o (p = 0,02) de las metástasis, así como el tiempo libre de enfermedad (p = 0,012). La vía de abordaje, así como la técnica de resección empleada, no influyeron en la supervivencia global a los 3 a os ni en el intervalo libre de enfermedad, siempre que todas las metástasis fueran resecadas (p > 0,05). La técnica de resección permitió la exéresis de todas las lesiones detectables, con un margen de tejido sano, y se preservó al máximo el parénquima pulmonar. El volumen adecuado y la técnica de resección dependieron del número, tama o y localización de las lesiones. El tiempo de seguimiento mínimo fue de 3 a os. CONCLUSIONES. El intervalo libre de enfermedad fue identificado como el factor más importante para el pronóstico. El análisis de supervivencia nos permitió estratificar a los pacientes en grupos de riesgo según la progresión del tumor y sobre la base del tama o y número de las lesiones y del intervalo libre de la enfermedad tras la escisión del tumor primario. INTRODUCTION. The aim of this paper was to identify the prognostic factors related to higher survival after lung metastasectomy for all types of primary tumor performed in the National Institute of Oncology and Radiobiology of Cuba. METHODS. An ambispective nonrandomized study was undertaken. The study group was composed of patients with lung metastases of intra- or extrapulmonary origin. RESULTS. In the univariate analysis, the number (p = 0.004) and size (p = 0.02) of the metastasis, as well as the disease free time (p = 0.012) proved to be positive predictive indicators of a longer disease free interval and a higher global survival at 3 years. The approach route and the resection technique used did not influence either on global survival at 3 years or on the disease free interval, provided that all the metastases were resected (p > 0.05). The resection technique allowed the exeresis of all the detectable lesions with a margin of sound tissue, and lung parenchyma was pr
Fenotipo y genotipo de once pacientes con Ataxia de Friedreich: Phenotype and Genotype in Eleven Patients
Vargas,Elizabeth; Villegas,Victoria Eugenia; Pedraza,Olga Lucía; Durán,Clemencia; Prieto,Juan Carlos;
Revista Ciencias de la Salud , 2006,
Abstract: introduction: - friedreich's ataxia is an autosomal recessive disease due to a mutation in gene x25. this gene codes for frataxin and it is located on chromosome 9. the disease is caused by a triplet particular sequence of bases (gaa). normally, the gaa sequence is repeated 7 to 22 times, but in people with friedreich's ataxia, it can be repeated hundreds or even over thousand times. objectives: to determine if there is a correlation between clinical and molecular findings in our frda patients. methods: eleven patients with the typical friedreich′s ataxia phenotype were studied by pcr we determined the size of the gaa expansions, and analyzed the correlation of age at onset and rate of disease progression with the number of gaa repetitions. results and conclusions: molecular analysis by pcr showed eight homozygous patients for the expansion and three negative. the average of the size of the expansions in the allele was of 622±5 with an average in the age of beginning of 13±8. for the sample size, there was no significant statistical correlation between the age of beginning of the disease and the number of repetitions, although there was like an inverse correlation. besides understanding of frda physiology and the harding clinical inclusion criteria, molecular diagnosis is an important step in the achievement of an optimal therapeutic treatment.
Clinical outcomes of lung metastasectomy in patients with colorectal cancer  [cached]
Omer Fatih Olmez,Erdem Cubukcu,Ahmet Sami Bayram,Unsal Akcali
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i7.662
Abstract: AIM: To investigate prognostic factors of survival following curative, non-palliative surgical removal of lung metastases secondary to colorectal cancer (CRC). METHODS: Between 1999 and 2009, a radical metastasectomy with curative intent was performed on lung metastases in 21 patients with CRC (15 male and 6 female; mean age: 57.4 ± 11.8 years; age range: 29-74 years) who had already undergone primary tumour resection. RESULTS: The mean number of lung metastases ranged from one to five. The mean overall survival was 71 ± 35 mo (median: 25 mo). After adjusting for potential confounders, multivariable Cox regression analyses predicted only the number of lung metastases (1 vs ≥ 2; hazard ratio: 7.60, 95% confidence interval: 1.18-17.2, P = 0.03) as an independent predictor of poor survival following lung resection for metastatic CRC. CONCLUSION: Resection of lung metastases is a safe and effective treatment in selected CRC patients with single lung metastases.
Pulmonary metastasectomy from soft tissue sarcomas
Sardenberg, Rodrigo Afonso da Silva;Figueiredo, Luiz Poli de;Haddad, Fábio José;Gross, Jefferson Luiz;Younes, Riad Naim;
Clinics , 2010, DOI: 10.1590/S1807-59322010000900010
Abstract: introduction: isolated pulmonary metastases from soft tissue sarcomas occur in 20-50% of these(the issue is about metastases, not lung cancer )patients, and 70% of these patients will present disease limited only to the lungs. surgical resection is well accepted as a standard approach to treat metastases from soft tissue sarcomas isolated in the lungs, and many studies investigating this technique have reported an overall 5-year survival ranging from 30-40%. the most consistent predictor of survival in these patients is complete resection. the aim of the present study was to determine the demographics and clinical treatment-related variables associated with long-term (90-month) overall survival in patients with lung metastases undergoing pulmonary metastasectomy from soft tissue sarcomas. methods: we performed a retrospective review of patients admitted in the thoracic surgery department with lung metastases who underwent thoracotomy for resection following treatment of the primary tumor. data regarding primary tumor features, demographics, treatment, and outcome were collected. results: one hundred twenty-two thoracotomies and 273 nodules were resected from 77 patients with previously treated soft tissue sarcomas. the median follow-up time of all patients was 36.7 months (range: 10-138 months). the postoperative complication rate was 9.1%, and the 30-day mortality rate was 0%. the 90-month overall survival rate for all patients was 34.7%. multivariate analysis identified the following independent prognostic factors for overall survival: the number of metastases resected, the disease-free interval, and the number of complete resections. conclusion: these results confirm that lung metastasectomy is a safe and potentially curative procedure for patients with treated primary tumors. a select group of patients can achieve long-term survival after lung resection.
Once a os de experiencia en el manejo de la retinopatía del prematuro en las Islas Baleares Eleven years experience in the management of retinopathy of prematurity in the Balearic Islands  [cached]
FJ Monta?ez,JL Olea
Archivos de la Sociedad Espa?ola de Oftalmología , 2005,
Abstract: Objetivo: Evaluar la incidencia y eficacia del tratamiento en Retinopatía del Prematuro (ROP) de los prematuros nacidos en Baleares. Material y métodos: Estudio protocolizado, prospectivo y consecutivo. Se han incluido los ni os prematuros cuyo peso al nacimiento era inferior a 1.501 gr o superior si requirieron oxigenoterapia intubada. Se analizan los datos entre enero de 1992 y diciembre de 2003. Se ha evaluado la edad gestacional, estadio y tratamiento siguiendo las indicaciones del estudio CRYO-ROP. Se efectúa un estudio descriptivo de las variables cuantitativas y cualitativas evaluadas. Resultados: Se han evaluado 446 ni os. Edad media 30,4 semanas y peso medio 1.178,38 gr, encontrándose ROP para peso < 1.000 gr en 93 ni os (63,1%), 1000-1500 en 50 (19,6%) y >1.500 en 5 (11,4%). Edad gestacional < 27 en 44 ni os (86,2%), 27-30 en 87 (35,2%) y >30 en 19 (12,7%). Con estadios III hubo 75 ni os y requirieron tratamiento el 73,3%. La ablación retiniana se realizó a los 62,95 días desde la fecha de nacimiento. Conclusiones: La incidencia de ROP está relacionada inversamente con peso al nacimiento y edad de gestación. Tres de cada 4 ni os que llegaron a estadios III requirieron tratamiento. La eficacia de la fotocoagulación retiniana fue superior al 90% y tuvo que aplicarse a los 2 meses tras el nacimiento. Purpose: To evaluate the incidence and effectiveness of the treatment of Retinopathy of Prematurity (ROP) in preterm births in the Balearic Islands. Materials and methods: Protocol of prospective and consecutive study. We included preterm infants whose birth weights were under 1,501 g, or heavier infants requiring assisted oxygen therapy. Data for the 12 years between January 1992 and December 2003 were analyzed. We evaluated gestational age, birth weight, ROP stage and the effect of treatment following CRYO-ROP Study indications. A descriptive study was undertaken. Results: We evaluated 446 babies. Average age and weight were 30.4 weeks and 1,178.4 g respectively. ROP was found in 93 infants (63.1%) weighing less than 1,000 g, in 50 (19.6%) weighing 1,000-1,500 g and in 5 (11.4%) weighing >1,500 g. In regard to gestation, ROP was found in 27 (86.2%) babies born at < 27 weeks of gestation, in 87 (35.6%) born at 27-30 weeks of gestation and in 19 infants (12.7%) born at > 30 weeks gestation. There were 75 babies with stage III disease and 73.3% needed treatment. Retinal ablation was performed at 62.9 days. Conclusions: ROP incidence is inversely related to birth weight and gestational age. Three out of four babies who reached stage III disease needed
Cinco pacientes, once colgajos libres: resultados a largo plazo Five patients, eleven free flaps: long-term results  [cached]
C. Olvera Caballero
Cirugía Plástica Ibero-Latinoamericana , 2006,
Abstract: Los colgajos libres resuelven problemas complejos. En situaciones en donde existe gran pérdida de tejidos u otros métodos reconstructivos han fracasado se puede lograr restablecer la forma y la función utilizándolos. En este trabajo se presentan cinco pacientes en los que se usaron once colgajos libres (2 por paciente en cuatro casos, tres en otro) y sus resultados a largo plazo con un mínimo de seguimiento de 7 a os y un máximo de 17 a os. Las indicaciones para utilizar más de un colgajo libre en un paciente son: reponer un primer colgajo perdido, por complejidad del problema, por experiencia del cirujano o por deseo expreso del paciente para una reconstrucción similar. En nuestra serie, la complejidad del problema fue la principal indicación de usar este método doble y triple. Cuatro pacientes recibieron los colgajos en los miembros inferiores y uno en la cara. Las etiologías encontradas fueron: secuelas de quemaduras en dos casos, secuelas posttraumáticas en otros dos y secuelas postquirúrgicas y de mielomeningocele en uno. Se utilizaron cuatro colgajos de dorsal ancho, cinco escapulares, uno de peroné y uno de gracilis. El seguimiento a largo plazo nos permite mostrar la gran adaptabilidad de los colgajos libres, su resistencia y su valor como procedimiento reconstructivo de primera opción Free flaps are useful to solve complex problems. Whenever there is an extensive loss of tissues or when other reconstructive methods have failed, they may provide the means to restore shape and function. This paper deals with five patients in whom eleven free flaps were used (two in four patients and three in one more case) to solve complex problems. Furthermore, long-term results are reported, with follow-up ranging from 7 to 17 years Indications to use more than one free flap in a patient are: replacing a first flap that was lost, a highly complex problem, the surgeon’s expertise, or when the patient wish for a similar reconstruction. In this series, complexity of the problem was the main indication for the double method. The recipient zone was the lower extremities in four of the patients and the face in the fifth. The etiology were burn sequelae in two, post-traumatic sequelae in two and postsurgical and mielomeningocele sequelae in one. Four latissimus dorsi flaps, five scapular flaps one peroneus and one gracilis flaps were used. The recipient sites and surgical technique are described. Long-term follow-up makes it possible to demonstrate the outstanding adaptability of free flaps, their resilience and their usefulness as a first-choice reconstructive proced
Hongos Basidiomycota, no laminados en once municipios del estado Zulia, Venezuela. Basidiomycota non gilled mushrooms in eleven municipalities in Zulia State, Venezuela.
A. E. Delgado A.,A. J. Pi?eiro Ch.,L. M. Urdaneta G.
Revista de la Facultad de Agronomía , 2002,
Abstract: Durante los a os 1999-2000, se colectaron 129 muestras en 11 municipios del estado Zulia, Venezuela de hongos Basidiomycota no laminados pertenecientes a las clases: Gasteromycetes, Phagmobasidiomycetes, Teliomycetes, Hemibasidiomycetes y el orden: Aphyllophorales. A cada hongo colectado, le fueron determinadas las características del pileo, poros, estípe o talo, depósito de esporas, profundidad del tubo, forma y dimensiones de las esporas y tipo de hábitat. Treinta y cuatro géneros y cuarenta y ocho especies fueron identificadas, siendo los géneros: Aquascypha, Auricularia, Ceratelium, Cintractia, Coltricia, Cyathus, Fomes, Ganoderma, Hexagonia, Irpex, Laetiporus, Lenzite, Picnosporus, Pisolithus, Polyporus, Schizophylum y Sparassis los más comunes y por vez primera para Venezuela fueron colectadas las siguientes especies: Calvatia elata, Cyathus olla, C. striatus, , Coltricia montagnei, Ganoderma curtesii, Lenzite betulina, Meruliopsis taxicola, Phellinus chysoloma, P. viticola, Plycaturopsis crispa, Sparassis crispa, S. spathulata y Trametes gibbosa. During a the years 1999 and 2000, one hundred twenty nine (129) samples of non-gilled fungi of differents classes and order were collected in eleven municipalities in Zulia State, Venezuela: Gasteromycetes, Phragmobasidiomycetes, Teliomycetes, Hemibasidiomycetes and the Aphyllophorales order . For each fungus collected the characteristics of the pileus, porus, stipe, tubes depth, spore deposit, spore form and size, and habitat type were determined. Thirty-four genus and forty eight species were identified, the genus: Aquascypha, Auricularia, Ceratelium, Cintractia, Coltricia, Cyathus, Fomes, Ganoderma, Hexagonia, Irpex, Laetiporus, Lenzite, Picnosporus, Pisolithus, Polyporus, Schizophylum y Sparassis were the most common, and for the first time Venezuela the following species were collected: Calvatia elata, Cyathus olla, C. striathus, Coltricia montagnei, Ganoderma curtesii, Lenzite betulina, Meruliopsis taxicola, Phellinus chysoloma, P. viticola, Plycaturopsis crispa, Sparassis crispa, S. spathulata and Trametes gibbosa.
Page 1 /100
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.