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Juvenile psammomatoid ossifying fibroma. Case report
Alexandros VALASIDIS,Aris NTOMOUCHTSIS,Antonis TSEKOS,Giorgos BALLIS
Hellenic Archives of Oral and Maxillofacial Surgery , 2012,
Abstract: Ossifying fibroma (OS) represents a slow growing, benign neoplasm that belongs to the greater group of fibro-osseous lesions. Based on its histological features, ossifying fibroma is divided into: a) juvenile trabecular OS and b) juvenile psammomatoid OS which affects mainly the paranasal sinuses of children and teenagers aging from 5 to 15 years.A rare case of juvenile psammomatoid ossifying fibroma in a 30 year old male patient located in the left mandibular ramus is presented. Treatment plan included radical surgical excision of the lesion and restoration with autologous osteochondral graft from the 6th rib of the ipsilateral side.
Juvenile Ossifying Fibroma of the Mandible: a Case Report  [PDF]
Bahar Keles,Mutlu Duran,Yavuz Uyarhttp://www.doaj.org/restricted,Ahmet Azimov
Journal of Oral & Maxillofacial Research , 2010,
Abstract: Background: Fibro-osseous lesions of the jaws, including juvenile ossifying fibroma, pose diagnostic and therapeutic difficulties due to their clinical, radiological and histological variability. The aim of this study was to report the outcome of a 9 years old girl with diagnosed juvenile ossifying fibroma treatment.Methods: A 9 years old girl presented with a 6 x 8 cm sized hard fixed tumour on right ramus and corpus of the mandible. On the radiological examination tumour showed an irregular but well bordered, unilocular and expansive lesion on the right corpus and ramus of the mandible. There was no teeth displacement or teeth root resorbtion. Microscopically, the tumour had trabeculae, fibrillary osteoid and woven bone. After the clinical, radiological (panoramic radiography, computed tomography and magnetic resonance imaging) and histologic analysis it was diagnosed juvenile ossifying fibroma. In the history of the patient there has been an acute lymphocytic leukaemia in the remission for 3 years.Results: Because of large size of mandibular tumour, resultant expansion and destruction of mandibular cortex, the patient underwent right hemimandibulectomy using transmandibular approach. There was no recurrence or complications for two years follow-up.Conclusions: Although juvenile ossifying fibroma is an uncommon clinical entity, its aggressive local behaviour and high recurrence rate means that it is important to make an early diagnosis, apply the appropriate treatment and, especially, follow-up the patient over the long-term.
Synchronous Juvenile ossifying Fibroma in maxilla and mandible- A case report  [PDF]
B Shrestha,S Subedi,S Pandey
Journal of Chitwan Medical College , 2014, DOI: 10.3126/jcmc.v4i2.10867
Abstract: Juvenile ossifying fibroma (JOF), one of the fibroosseous lesions is an uncommon clinical entity and involving both jaw is even rarer. Here, we present the case of a 15-year-old female patient with synchronous occurrence of JOF in the right sided maxilla and in the periapical area of mandibular right premolar molar region. After the clinical, radiographical and histopathological examination, the surgical treatment was carried out and the patient was kept under long term follow up. Owning to its aggressive local behaviour and high recurrence, early diagnosis, appropriate treatment and long term regular follow up are of prime importance. DOI: http://dx.doi.org/10.3126/jcmc.v4i2.10867 Journal of Chitwan Medical College 2014; 4(2): 54-57
Juvenile Aggressive Ossifying Fibroma in a 6-Months Old: A Case Report  [PDF]
Mmathabo Gloria Sekhoto, Risimati Ephraim Rikhotso
Open Journal of Stomatology (OJST) , 2017, DOI: 10.4236/ojst.2017.711044
Abstract: Juvenile Aggressive Ossifying Fibroma (JAOF) is a benign but locally aggressive fibro-osseous lesion. It is a rapidly growing non-odontogenic neoplasm of the jaws, generally occurring in children and young adults. It is often confused with malignant condition because of its clinical behaviour. Long term follow-up is necessary, considering the high recurrence nature of this tumour. The reconstruction of affected patients, particularly the younger, is often challenging since it has to be done in stages, to keep up with the developing face. We report a case of maxillary JAOF in a 6-month-old female who was referred to our department. Histopathological examination of a resected specimen revealed a trabecular type of JAOF. The patient was followed up for a period of 2 years.
Fibroma osificante juvenil activo trabecular, deformante: Reporte de un caso Deformity by a Trabecular Juvenile Active Ossifying Fibroma: A case report
Orlando Yoris,Ligia Pérez,Cesar Molina,Luís Sarmiento
Acta Odontológica Venezolana , 2009,
Abstract: El fibroma osificante juvenil activo trabecular (FJOAT), es una variante histológica del fibroma osificante, que forma parte de la familia de lesiones fibro-óseas benignas, cuya característica común, es la sustitución del hueso medular por tejido fibroso con cantidades variables de hueso o cementoide. Aparece con mayor frecuencia en los huesos cráneo-faciales de individuos entre los 12 y 15 a os de edad, comportándose como una lesión agresiva y recidivante. El propósito de este artículo es reportar, un paciente masculino, de 16 a os quien acude al servicio de cirugía bucal en esta institución, por una marcada asimetría facial del tercio superior y medio del lado derecho, asintomática, con cinco a os de evolución. Imagenologicamente se observa masa ocupante de espacio, en seno maxilar, cavidad nasal, extendiéndose al piso de la orbita del lado afectado y a estas mismas estructuras homologas del lado contrario. La biopsia incisional reveló un fibroma osificante juvenil activo, tipo trabecular. La eliminación total de la lesión y su estudio, corroboró el diagnostico. Se demuestra hasta donde es capaz de causar deformidad esta patología y se recalca la importancia del trabajo en equipo transdisciplinario y del estudio microscópico para llegar a un diagnostico definitivo. The juvenile active ossifying fibroma, trabecular type, is a histological variant of ossifying fibroma, which belong to the benign fibrous osseous lesions family, being its common feature the replacement of medullar bone by fibrous tissue with variable quantity of bone and/or cementoide. It is found on the cranial facial bones in 12 to 15 years old patients, behaving in an aggressive fashion. The purpose of this paper is to report, a sixteen years old male patient, who went for consultation to the oral surgery service at this institution, due to a marked right facial asymmetry, asymptomatic, for five years. The computerized tomography showed a mass involving right maxillary sinus and nasal cavity, extending to the inferior border of the orbit enclosing the homologous structures on the left side. The incisional biopsy revealed a trabecular juvenile active ossifying Fibroma. The excisional biopsy confirmed this diagnosis. It is shown how this lesion is capable to cause a marked facial asymmetry and how is important the microscopic study of the lesions in order to get a precise diagnosis.
Juvenile aggressive ossifying fibroma of the maxilla  [cached]
Shekhar M,Bokhari K
Journal of the Indian Society of Pedodontics and Preventive Dentistry , 2009,
Abstract: Juvenile aggressive ossifying fibroma is an uncommon and controversial, benign but aggressive osteogenic neoplasm of the jaws commonly occurring in children and young adults. Complete removal of the tumor at the earliest possible stage is recommended owing to its high recurrence rate of 30-58%. Reported here is a case of recurrent juvenile aggressive ossifying fibroma of the maxilla in a 15-year-old male treated with enucleation and curettage. A 10-month follow-up showed no signs of recurrence.
Peripheral Ossifying Fibroma: A Clinical Report
Nazareth,Bianca; Arya,Harshwardhan; Ansari Ritika Arora,Salman; Arora,Ritika;
International journal of odontostomatology , 2011, DOI: 10.4067/S0718-381X2011000200007
Abstract: localized growths are commonly seen on the gingiva. many of these enlargements are considered to be reactive rather than neoplastic in nature. clinically differentiating one from the other as a specific entity is often not possible. histopathologic examination is needed in order to positively identify the lesion. the peripheral ossifying fibroma is one such lesion. we report in this study, the clinical report of a 20-yr-old male patient with a peripheral ossifying fibroma in the maxilla exhibiting significant size with the disease duration of 1 year. the signs of recurrence in spite of thorough excision and debridement exposed the need for further study of the causes of recurrence and possible modes to avoid the situation. clinical, radiographical and histological characteristics are discussed and recommendations regarding treatment and follow-up are provided.
Trabecular variant of juvenile aggressive ossifying fibroma of anterior mandible  [cached]
Manjunatha BS,Nagarajappa Das,Saraswati Naik,Gowramma R
Pediatric Reports , 2012, DOI: 10.4081/pr.2012.e24
Abstract: Juvenile ossifying fibroma (JOF) is an expansile intra-osseous lesion of the jaw that emulate odontogenic lesions frequently seen in patients under 15 years of age. They are histologically characterized by the presence of fibrous stromal cells along with mineralized tissues. Clinically, these are characterized by early age of onset, histological patterns, high rate of recurrence and the aggressive local behavior. The differential diagnosis of JOF with other fibro-osseous lesions of the jaw should be made along with an essential microscopic examination and be largely based on the character of the calcified products of the tumor. The purpose of this article is to present a rare clinical case of the trabecular type of JOF and to describe its clinical, radiological and histological characteristics. The clinician should be aware of this type of lesion in order to be able to distinguish this it from other fibrous lesions if encountered in routine practice and for appropriate treatment to be carried out.
A VOLUMINOUS OSSIFYING FIBROMA OF THE MANDIBLE - CASE REPORT  [PDF]
D. Gogalniceanu,Daniela Trandafir,Carmen Vicol,Violeta Trandafir
Jurnalul de Chirurgie , 2006,
Abstract: Ossifying fibroma is a rare, benign fibro-osseous tumor that most commonly occurs in the bones of the craniofacial skeleton. This well-demarcated lesion is composed of fibrocellular tissue and mineralized material of varying appearances. Ossifying fibroma is a slow-growing, asymptomatic neoplasm that can reach a very large size. Differentiation from other forms of fibro-osseous lesions, such as monoostotic fibrous dysplasia, is often quite difficult. This paper presents a rare case of a voluminous mandibular ossifying fibroma which gave us serious problems of diagnosis and treatment. We have performed a bloc osseous resection which has preserved the alveolar border and has permitted (by apical resections) the conservation all the dents which apical roots were included in the tumoral aria. Surgical treatment in this case has also needed (in the same operation) a reconstructive surgery (because of the estetic and functional considerents). The defect created by the excision of this large lesion was reconstructed with an iliac bone graft and a titanium reconstruction's atela.
The varying clinical presentations of peripheral ossifying fibroma: a report of three cases
Pal, Sumona;Hegde, Shruthi;Ajila, Vidya;
Revista Odonto Ciência , 2012, DOI: 10.1590/S1980-65232012000300015
Abstract: purpose: gingival growths are one of the most frequently encountered lesions in the oral cavity. most of these lesions are innocuous, but some do have malignant potential. different lesions with similar clinical presentations make it difficult to arrive at a correct diagnosis. one of the infrequently occurring gingival lesions is peripheral ossifying fibroma (pof). lesions with histological features similar to pof have been given various names, adding to the confusion. we report the varied clinicopathological features of 3 cases of pof, discuss the contentious nomenclature and investigate the possible etiopathogenesis of this disease. case description: three cases of gingival growths (pof) are reported. two of the lesions occurred in the maxillary anterior region, while the third occurred in the mandibular posterior region. two of the cases showed radiographic evidence of bone loss. an excision biopsy was performed in all three cases. conclusion: because the rate of recurrence for peripheral ossifying fibroma is 8% to 20%, close postoperative monitoring is required. it is also necessary to use consistent and specific nomenclature in the literature to avoid confusion and the loss of important data.
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