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Y(4143) is probably a molecular partner of Y(3930)  [PDF]
Xiang Liu,Shi-Lin Zhu
Physics , 2009, DOI: 10.1103/PhysRevD.80.017502
Abstract: After discussing the various possible interpretations of the Y(4143) signal observed by the CDF collaboration in the $J/\psi \phi$ mode, we tend to conclude that Y(4143) is probably a $D_s^\ast {\bar D}_s^\ast$ molecular state with $J^{PC}=0^{++}$ or $2^{++}$ while Y(3930) is its $D^\ast {\bar D}^\ast$ molecular partner as predicted in our previous work (arXiv:0808.0073). Both the hidden-charm and open charm two-body decays occur through the rescattering of the vector components within the molecular states while the three- and four-body open charm decay modes are forbidden kinematically. Hence their widths are narrow naturally. CDF, Babar and Belle collaborations may have discovered heavy molecular states already. We urge experimentalists to measure their quantum numbers and explore their radiative decay modes in the future.
Medicina molecular: Presente y futuro
Zanlungo M,Silvana; Arrese J,Marco; Rigotti R,Attilio;
Revista médica de Chile , 1999, DOI: 10.4067/S0034-98871999000800014
Abstract: the genetic background of individuals is recognized as an important clue in the analysis of classical hereditary and multifactorial acquired diseases. this new concept derives from the development and increasing use of molecular genetics in clinical medicine. the application of molecular biology techniques in biomedical investigation has encompassed the identification of the pathogenesis and etiology of diseases, prenatal diagnosis the production of new therapeutic agents, gene therapy and the development of pharmacogenetics. the impact on the fundamentals and practice of clinical medicine that will have the use of molecular biology is analyzed in this review.
$Y(4260)$ as the first $S$-wave open charm vector molecular state?  [PDF]
Martin Cleven,Qian Wang,Feng-Kun Guo,Christoph Hanhart,Ulf-G. Mei?ner,Qiang Zhao
Physics , 2013, DOI: 10.1103/PhysRevD.90.074039
Abstract: Since its first observation in 2005, the vector charmonium $Y(4260)$ has turned out to be one of the prime candidates for an exotic state in the charmonium spectrum. It was recently proposed that the $Y(4260)$ should have a prominent $D_1\bar{D}+c.c.$ molecular component that is strongly correlated with the production of the charged $Z_c(3900)$. In this paper we demonstrate that the nontrivial cross section line shapes of $e^+e^-\to J/\psi\pi\pi$ and $h_c\pi\pi$ can be naturally explained by the molecular scenario. As a consequence we find a significantly smaller mass for the $Y(4260)$ than previous studied. In the $e^+e^-\to \bar D D^*\pi+c.c.$ process, with the inclusion of an additional $S$-wave $\bar D^*\pi$ contribution constrained from data on the $D\bar D^*$ invariant mass distribution, we obtain a good agreement with the data of the angular distributions. We also predict an unusual line shape of $Y(4260)$ in this channel that may serve as a smoking gun for a predominantly molecular nature of $Y(4260)$. Improved measurements of these observables are therefore crucial for a better understanding of the structure of this famous resonance.
The open-charm radiative and pionic decays of molecular charmonium Y(4274)  [PDF]
Jun He,Xiang Liu
Physics , 2011, DOI: 10.1140/epjc/s10052-012-1986-1
Abstract: In this work, we investigate the decay widths and the line shapes of the open-charm radiative and pionic decays of Y(4274) with the $D_s\bar{D}_{s0}(2317)$ molecular charmonium assignment. Our calculation indicates that the decay widths of $Y(4274)\to D^{+}_{s}D^{*-}_{s}\gamma$ and $Y(4274)\to D^+_{s}D^-_{s}\pi^0$ can reach up to 0.05 keV and 0.75 keV, respectively. In addition, the result of the line shape of the photon spectrum of $Y(4274)\to D_s^+ {D}_s^{*-} \gamma$ shows that there exists a very sharp peak near the large end point of photon energy. The line shape of the pion spectrum of $Y(4274)\to D_s^+ {D}_s^{*-} \pi^0$ is similar to that of the pion spectrum of $Y(4274)\to D_s^+ {D}_s^{*-} \gamma$, where we also find a very sharp peak near the large end point of pion energy. According to our calculation, we suggest further experiments to carry out the search for the open-charm radiative and pionic decays of Y(4274).
Medicina molecular: Presente y futuro Molecular medicine: Present and future  [cached]
Silvana Zanlungo M,Marco Arrese J,Attilio Rigotti R
Revista médica de Chile , 1999,
Abstract: The genetic background of individuals is recognized as an important clue in the analysis of classical hereditary and multifactorial acquired diseases. This new concept derives from the development and increasing use of molecular genetics in clinical medicine. The application of molecular biology techniques in biomedical investigation has encompassed the identification of the pathogenesis and etiology of diseases, prenatal diagnosis the production of new therapeutic agents, gene therapy and the development of pharmacogenetics. The impact on the fundamentals and practice of clinical medicine that will have the use of molecular biology is analyzed in this review.
Avances en nutrición molecular: nutrigenómica y/o nutrigenética Advances in molecular nutrition: nutrigenomics and/or nutrigenetics  [cached]
A Marti,M.a J Moreno-Aliaga,M.a A Zulet,J. A Martínez
Nutrición Hospitalaria , 2005,
Abstract: La aplicación de las técnicas de la biología molecular y el éxito del Proyecto Genoma Humano ha abierto una nueva era tanto en Medicina como en Nutrición. Hasta la fecha, al menos, 1.000 genes humanos causantes de enfermedades han sido identificados y parcialmente caracterizados, el 97% de los cuales sabemos ahora que son causantes de enfermedades monogénicas. Sin embargo, otras patologías como la obesidad, enfermedad cardiovascular, diabetes, cáncer se deben a complejas interacciones entre diversos genes y factores ambientales. A pesar de los numerosos estudios de asociación, más de 600 publicados desde 2002, la base molecular de las enfermedades crónicas es todavía incierta. La información sobre polimorfismos de nucleótidos y mapas de haplotipos son recursos adicionales para identificar genes involucrados en enfermedades. El desarrollo genómico se aproxima, sin embargo, no se conocen con precisión algunos componentes de la dieta y sus mecanismos, que influyen de forma importante en la expresión de la información genética y en las alteraciones patológicas. La industria alimentaria tiene la oportunidad de utilizar los componentes bioactivos de los alimentos para mejorar la salud y evitar las enfermedades teniendo en cuenta la constitución genética de los consumidores. Esta nueva era de la nutrición molecular "interacciones genes-nutrientes" puede crecer en diversas direcciones, aunque hay dos esenciales. De una parte, el estudio de la influencia de los nutrientes sobre la expresión de genes (nutrigenómica) y de otra conocer la influencia de las variaciones genéticas en la respuesta del organismo a los nutrientes (nutrigenética). The application of molecular biology techniques and the success of the Human Genome Project have opened a new era for both Medicine and Nutrition. To date, at least 1,000 human genes causing disease have been identified and partially characterized, 97% of which we now know that are the cause of monogenic diseases. However, other diseases such as obesity, cardiovascular disease, diabetes, and cancer are due to complex interactions between several genes and environmental factors. In spite of the many association studies, over 600 published since 2002, the molecular base of chronic diseases is still uncertain. Information about nucleotide polymorphisms and haplotypes maps is an additional resource for identifying genes implicated in diseases. Genomic development gets close, however we frequently do not accurately know the dietary components and their mechanisms that importantly influence on genetic information expression and its pa
Molecular Nanostructures on the Surface of a d_(x2-y2)-Superconductor  [PDF]
Roy H. Nyberg,Dirk K. Morr
Physics , 2004,
Abstract: We study molecular nanostructures on the surface of a d_(x2-y2)-wave superconductor. We show that the interplay between the molecular nanostructure's internal excitation spectrum and quantum interference of the scattered host electrons leads to a series of novel effects in the local density of states. We demonstrate that these effects give insight into both the nature of the superconducting pairing correlations and of the intermolecular interactions.
Biología molecular en Infectología: Parte I: Desarrollo y metodologías MOLECULAR BIOLOGY IN INFECTIOUS DISEASES: PART I. DEVELOPMENT AND METHODOLOGIES  [cached]
ALEJANDRO CORVALáN R.
Revista chilena de infectología , 2002,
Abstract: El origen de la biología molecular se puede rastrear hasta fines del siglo XIX; sin embargo, el descubrimiento de la estructura del ADN se considera como el inicio de esta disciplina. Los avances producidos por la biología molecular en la década del ′60 nos permiten contar hoy con herramientas para el estudio de microorga-nismos a nivel molecular. En particular, el descubrimiento de la ADN polimerasa y las propiedades de hibridación del ADN son algunos de los descubrimientos que aplicados hoy día en la reacción de polimerasa en cadena, la amplificación isotérmica y la hibridación con ADN ramificado, se han transformado en herramientas útiles en el diagnóstico y cuantificación de agentes infecciosos. Finalmente la secuenciación de genomas bacterianos completos permitirá el desarrollo de nuevos métodos para el diagnóstico y tratamiento de enfermedades infecciosas Eventhough Molecular Biology was iniciated at the end of the XIX century, the discovery of the structure of DNA is considered the beginning of this field. Advances during 1960-1970 produced methods and technologies to study microorganisms at molecular level. In particular, the discovery of DNA polymerase and the specificity of DNA reanaturation are the bases for Polymerase Chain Reaction, Transcription Mediated Amplification, and Branched DNA methods useful for diagnosis and direct quantitation of infectious agents. Finally, the complete genome sequence should ultimately result in new methods for diagnosing and treating infectious diseases
A modified molecular sieve Y for hydrocracking
组合改性Y型分子筛的加氢裂化性能

王文兰,刘百军,高山松,李敏
燃料化学学报 , 2009,
Abstract: Molecular sieve Y was modified by a combination of hydrothermal treatment,dealuminization with oxalic acid,and hydrothermal crystallization in the presence of the surfactant cetyl trimethyl ammonium bromide(CTAB).The effects of CTAB amount used on the crystallinity,unit cell constant,SiO2/Al2O3 ratio,surface area and pore structure of the modified molecular sieve Y were investigated.NH3-TPD was employed to characterize the acidity.The results showed that after modification,the crystallinity and SiO2/Al2O3 r...
Resultados relevantes en biología molecular, enzimopatías y citogenética en el período 1996-2010 Relevant results in molecular Biology, enzymopathies and citogenetics during 1996-2010
Ana María Amor-Vigil,Gisela Martínez-Antu?a,Kalia Lavaut-Sánchez,Graciela Pérez-Diez de los Ríos
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2011,
Abstract: El Departamento de Biología Celular y Molecular del Instituto de Hematología e Inmunología incluye 4 áreas: biología molecular, hemoglobinopatías, enzimas y membrana eritrocitaria y citogenética. Se presentan aspectos relevantes del trabajo desarrollado en los últimos a os que comprende investigaciones en las talasemias que permitieron conocer las bases moleculares de estas hemoglobinopatías en nuestra población. En el campo de la biología molecular se desarrolló inicialmente la técnica del southern blot; posteriormente, la de la reacción en cadena de la polimerasa y la transcripción inversa, que han sido muy útiles en el diagnóstico y seguimiento de pacientes con hemopatías malignas. La presencia de alteraciones citogenéticas (monosomías, trisomías, translocaciones, inversiones y deleciones) ha sido ampliamente evaluada en enfermedades hematológicas, con gran utilidad también en el diagnóstico, pronóstico y seguimiento de los pacientes. En cuanto a las enzimopatías, se pudo conocer la alteración molecular de variantes deficientes de glucosa-6-fosfato deshidrogenasa y con el desarrollo de las técnicas para el estudio de las proteínas de la membrana eritrocitaria, se determinó la alteración bioquímica de enfermos con esferocitosis hereditaria (EH). The Department of Cellular and Molecular Biology of the Institute of Hematology and Immunology includes 4 areas: molecular biology, hemoglobinopathies, enzymes and erythrocytic and cytogenetic membrane. Authors show relevant features of work developed in past years including researches of thalassemia allowing us to know the molecular bases of these hemoglobinopathies in our population. In the field of molecular biology initially we developed the Southern Blot technique; later, that of the polymerase chain reaction (PCR) and the inverse transcription, both very useful in the diagnosis and follow-up of patients presenting with malignant hemopathies. The presence of cytogenetic alterations (monosomies, trisomies, translocations, inversions and deletions) has been fully assessed in hematologic diseases and also with a great usefulness in the diagnosis, prognostic and follow-up of the patients. As regards the enzymopathies, it was possible to know the molecular alteration of variants lacking in glucose-6-phosphate dehydrogenase and with the development of the techniques for the study of proteins of erythrocytic membrane it was possible to determine the biochemical alteration of patients presenting with hereditary spherocytosis (HS).
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