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Establishment of multivariate diagnosis and treatment system of modern gynecology of traditional Chinese medicine  [cached]
Jin-rong FU
Zhong Xi Yi Jie He Xue Bao , 2008,
Abstract: ABSTRACT: Gynecology of traditional Chinese medicine (TCM) is a clinical subject concentrating on women's specific diseases. With the advance of the time, clinical gynecology of TCM has to be developed from clinical practice and establish an open mode of multivariate diagnosis and treatment. The author of this article expatiates on the relationships between syndrome differentiation and disease identification, constitution differentiation and syndrome differentiation, stage differentiation and syndrome differentiation, time differentiation and syndrome differentiation, macroscopic differentiation of syndrome and microcosmic differentiation of syndrome, and integral syndrome differentiation and local syndrome differentiation, and then states that it is necessary for us to establish a multivariate diagnosis system to adapt to the complex clinical practice.
Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data
Matthias Samwald, Michel Dumontier, Jun Zhao, Joanne S Luciano, Michael Marshall, Kei Cheung
Chinese Medicine , 2010, DOI: 10.1186/1749-8546-5-43
Abstract: Ethnopharmacological findings are scattered over a multitude of publications and databases and are not well connected to other biomedical databases. As a result, the utility of these sources as knowledge resources are severely limited, which creates a further obstacle for modern day e-science research, which relies heavily on multiple heterogeneous data sources. Semantic technologies and standards, such as the Resource Description Framework (RDF) [1] and the Web Ontology Language (OWL) [2] provide technology that has potential to be used to help tackle the problem [3]. In recent years, relevant databases have been converted their data into the RDF/OWL format. This effort is exemplified by DartGrid, a toolkit for exposing relational datasets in RDF/OWL format [4]. A large-scale e-science infrastructure of datasets and ontologies for Chinese medicine was developed [5-7]. Unfortunately, the public accessibility to many of these resources is limited. This article proposes an alternate approach, using linked open data and Semantic Web technologies to address the heterogeneous data integration problem.We investigated the usefulness of openly available RDF/OWL tools and datasets to find evidence for pharmaceutical compounds from Chinese medicine that may treat depressive disorders or serve as lead compounds for the future pharmaceutical drug development. The reasons for choosing a psychological disorder were two-fold. Firstly, the development of traditional medicines such as Chinese medicine was mainly guided by symptomatological and introspective observations without the need for sophisticated experimental methods available only to modern medicine. Mental conditions, such as depression, are amenable to these kinds of phenomenological observations. It is possible to use traditional medicines to identify the source of pharmacological compounds that may otherwise be missed by modern rational drug design. Secondly, the conceptualization of mental conditions is diverse across
Discussion on definition of "traditional Chinese medicine and western medicine integration" and "integrated traditional Chinese and western medicine"  [cached]
CHEN Shi-Kui
Zhong Xi Yi Jie He Xue Bao , 2003,
Abstract: Objective: To discuss the definition of "traditional Chinese medicine and western medicine integration" and "integrated traditional Chinese and western medicine". Methods: Logic methods. Results: It was found that there were a lot of problems on the definition of "traditional Chinese medicine and western medicine integration" and "integrated traditional Chinese and western medicine". Conclusion: The understanding of the concepts of "traditional Chinese medicine and western medicine integration" and "integrated traditional Chinese and western medicine" was improved after the extensive discussion.
Diagnosis of pulmonary thromboemboli by tongue examination: an example for integration of Traditional Chinese Medicine and modern medicine
Majid Avijgan,Kiana Shirani,Mohsen Meidani
Journal of Experimental and Integrative Medicine , 2012,
Abstract: Phlegm in traditional Chinese medicine (TCM) is a sign for various problems caused by disturbance in fluid metabolism. We describe an example of using TCM concepts in combination with modern medicine investigations to diagnose pulmonary thrombo-emboli. A 71-year-old man with previous history of chronic obstructive pulmonary disease, heavy smoking and thrombosis in left leg vessels presented with signs and symptoms of lung infection. He was initially considered to be treated for pneumonia. Despite anticoagulant therapy his INR (international normalized ratio) was lower than expected. In addition on tongue examination we found a sign in TCM: dark reddish purple tongue with a thick greasy coat. Based on this clue we suspected that blood stasis could be the probable underlying cause for this condition. This primary diagnosis was confirmed by investigations including computed tomography-scan and doppler ultrasound. This sign helped us to think that thrombosis could be the possible cause for changes of tongue. [J Exp Integr Med 2012; 2(2.000): 185-188]
Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential
Ilkay Erdogan Orhan
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/946259
Abstract: This paper covers the studies relevant to neuroprotective activity of Centella asiatica (L.) Urban, also known as “Gotu Kola.” The plant is native to the Southeast Asia and has been used traditionally as brain tonic in ayurvedic medicine. The neuroprotective effect of C. asiatica has been searched using the key words “Centella, Centella asiatica, gotu kola, Asiatic pennywort, neuroprotection, and memory” through the electronic databases including Sciencedirect, Web of Science, Scopus, Pubmed, and Google Scholar. According to the literature survey, C. asiatica (gotu kola) has been reported to have a comprehensive neuroprotection by different modes of action such as enzyme inhibition, prevention of amyloid plaque formation in Alzheimer’s disease, dopamine neurotoxicity in Parkinson’s disease, and decreasing oxidative stress. Therefore, C. asiatica could be suggested to be a desired phytopharmaceutical with neuroprotective effect emerged from traditional medicine.
Characteristics of traditional Chinese medicine syndromes and their element distributions in sub-health status: a modern literature review  [cached]
Ya-jing ZHANG,Tian-fang WANG
Zhong Xi Yi Jie He Xue Bao , 2008,
Abstract: Objective: To probe into the characteristics of traditional Chinese medicine syndromes and their element distributions in sub-health status.Methods: Literatures on sub-health in past 20 years were collected, and a data bank was set up by using EpiData 2.0. The frequencies of syndromes and their elements were analyzed using SPSS 12.0.Results: Out of the 50 syndromes obtained from the standardization of syndrome nomenclature, and the top three were stagnation of liver-qi, deficiency of both heart and spleen, and deficiency of liver-yin and kidney-yin. Spleen, liver and kidney were the top three of all the 14 disease locations. Qi-deficiency, qi-stagnation and damp pathogen were the top three pathogenicity types.Conclusion: Although the traditional Chinese medicine syndromes in sub-health status are scattered in the distribution, the main syndromes take up a leading proportion and their elements are concise and concentrated in distribution. Therefore, it is necessary to make a standard study on traditional Chinese medicine syndromes in sub-health status from syndrome elements.
Micro-Holistic Body Model: Reconciliation of Traditional Chinese Medicine With Modern Biomedicine?
Aihua Xie
Iranian Journal of Medical Hypotheses & Ideas , 2011,
Abstract: Development of molecular biology reveals that multicellular organism could be considered as a cell community. By scrutinizing constitution and activities of a single cell under context of the whole community, I got a micro-holistic body model constituted of two aspects and seven compartments. The two inseparable aspects are the extracellular signalling molecules and the cells that communicate with each other using extracellular signalling molecules. The seven compartments include three universal sub-cellular compartments running within every cell in the body and four specific systems comprised of specific cell groups and molecules providing particular services needed generally by cells in the body. The constitution and internal relationship of the model match the fundamentals of traditional Chinese medicine (TCM) perfectly, thus can philosophically bridge the understanding between traditional Chinese medicine and western medicine, provide research hypotheses, and connect molecular level research with clinical diagnosis and treatment of complex diseases more directly, and may cause profound revolution in human healthcare technology.
A perspective of developing syndrome diagnostic criteria based on syndrome factors and combination of disease in modern medicine system and syndrome in traditional Chinese medicine system  [cached]
Tian-fang WANG
Zhong Xi Yi Jie He Xue Bao , 2009,
Abstract: : Syndrome differentiation treatment is the traditional model of diagnosis and treatment of diseases in traditional Chinese medicine (TCM). To establish scientific diagnostic criteria of TCM syndrome is one of the key points in TCM study. In this paper, the basic models of the relevant diagnostic criteria of TCM syndrome and existed problems were reviewed. The authors pointed out the advantages of establishing diagnostic criteria of TCM syndrome based on TCM syndrome factors and combination of disease in Western medicine system and TCM syndrome, in which not only the characteristics of the disease in Western medicine were considered, but also the complexity and flexibility of syndrome identification and convenient application in clinical practice were resolved. The basic model and frame of the above diagnostic criteria and the procedures and methods used in developing the diagnostic criteria were also described and discussed.
Traditional Chinese Medicine Modern Research and Its Industry Development
中药现代化研究关键问题与产业发展

Cheng Xianglin,
程翔林

世界科学技术-中医药现代化 , 2010,
Abstract: The Traditional Chinese Medicine (TCM) industry is an important component of China's pharmaceutical industry. Although TCM industry has achieved tremendous progress in recent years, it still faces enormous challenges. This paper introduces the current research progress in TCM and its industrialization from the following four aspects: new drug research and development as well as medicine industry, modern biotechnology and agriculture of TCM, Chinese medicine products development and its derivative industry, and standards for quality evaluation and industry.
An International Comparison of Attitudes Toward Traditional and Modern Medicine in a Chinese and an American Clinic Setting  [PDF]
Adam Burke,Tony Kuo,Rick Harvey,Jun Wang
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1093/ecam/nen065
Abstract: Introduction. International comparative research on traditional medicine (TM) offers a useful method for examining differences in patient characteristics and can provide insight into: (i) more universal characteristics which may cross cultures and international borders; (ii) unique characteristics influenced by regional/national factors; and (iii) cultural values of immigrant populations. To explore these issues TM patients from the United States and China were compared. Methods. Data collection took place at two TM college clinics. A convenience sample of 128 patients in China and 127 patients in the United States completed a 28-item questionnaire. Results. There was a marked similarity between the two patient groups in terms of the biological characteristics of age and gender. Musculoskeletal issues were the most common presenting complaints in the United States; while in China TM was used for a more diverse array of conditions. The majority of patients in both countries had initially used allopathic medicine (AM); significantly, more of the United States respondents stopped allopathic treatment after beginning traditional treatment. In comparing the two countries, patients in China were significantly more satisfied with AM and American patients significantly more satisfied with TM. In comparing the two medicines, the patient samples in both countries were significantly more satisfied with TM than AM. Discussion. Although treatment often originated with allopathic providers, many patients sought alternatives presumably to find the best solution to their problems. This tendency toward self-assignment suggests that a pluralistic healthcare system may provide the greatest satisfaction resulting from personal choice and improved outcomes. 1. Introduction National surveys have shown growing use of complementary and alternative medicine (CAM) by the general public [1–4]. Others have reported on the nature of use by specific populations, such as by disease [HIV/AIDS [5, 6] pain [7, 8] and cancer [9–11]], race/ethnicity [12, 13] or gender [14, 15]. More recently, increased attention has been focused on specific CAM therapies, including traditional East Asian medicine (TM) [16–19]. These studies have provided important information on demographics and the nature of use. Less common are studies examining why individuals elect to use specific CAM therapies, including studies that evaluate attitudes, beliefs and other sociocultural and psychosocial correlates of use, especially in relation to allopathic medical care. Such information would shed light on why
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