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Allergic and nonallergic rhinitis in children: The role of nasal cytology  [PDF]
Maria Cristina Provero, Alberto Macchi, Sara Antognazza, Maddalena Marinoni, Luigi Nespoli
Open Journal of Pediatrics (OJPed) , 2013, DOI: 10.4236/ojped.2013.32024
Abstract:

Nasal cytology is a diagnostic tool currently used in rhinology to study either allergic and vasomotor rhinological disorders or infectious and inflammatory rhinitis. Over the past few years nasal cytology has been rarely used in pediatrics, nevertheless its clinical and scientific applications seem to be very promising. The advantages of this technique are different: the ease of performance, the noninvasiveness allowing repetition and the low cost. We evaluated 100 children, from 2 to 15 years old, referred to our outpatient service for allergic children for suspected allergic rhinitis (AR). After skin prick test (SPT) or Radio Allergo Sorbent Test (RAST), 59/100 subjects were classified as affected by AR, while 8 children refused to be tested. According to ARIA guidelines, the 59 children with AR (4 - 15 years old) were divided in 56 with persistent AR and 3 with an intermittent form. Nine out of 59 children with AR had a significant number of neutrophils and eosinophils at the nasal cytology, documenting the presence of “minimal persistent inflammation”. Eleven out of 59 AR patients showed a positive swab for bacteria. Children with nonallergic rhinitis (NAR) were 33/100 (2 - 15 years old). After nasal cytology, 17/33 children were classified as NARES (nonallergic rhinitis with eosinophils), including one X-linked agammaglobulinemia (XLA) child, 1/33 as NARESMA (nonallergic rhinitis with eosinophils and mast cell) and another 1/33 as NARMA (nonallergic rhinitis with mast cell). In conclusion, nasal cytology allowed us to correctly classify children with NAR and to better assess the condition of children with AR.

The Role of Antihistamines in the Treatment of Vasomotor Rhinitis
Phil Lieberman
World Allergy Organization Journal , 2009, DOI: 10.1097/wox.0b013e3181b35322
Abstract: Nonetheless, at least one double-blind, placebo-controlled multicenter trial has found that intranasal azelastine relieves symptoms of this disorder better than placebo. The mechanism responsible for its beneficial effect in nonallergic rhinitis is unclear but probably relates to "anti-inflammatory/antiallergic" activities.Such mechanisms have been demonstrated for a number of different oral antihistamines, but often the concentrations required in vitro are higher than those that are normally achieved in vivo using recommended dosing. It has been postulated that intranasal administration, which can achieve high local levels, might be a factor responsible for enhancing the "anti-inflammatory/antiallergic" properties.Interpreting this information allows one to conclude that antihistamines may be potentially effective agents in vasomotor rhinitis, and are more likely to be so when administered intranasally, despite the fact that data documenting this beneficial effect are sparse.
Anticholinergic Drugs in Nonallergic Rhinitis
Robert Naclerio
World Allergy Organization Journal , 2009, DOI: 10.1097/wox.0b013e3181b35336
Abstract: Review of literature.Treatment with topical, intranasal anticholinergic drugs inhibits activation of the nasal mucosal glands and is effective in reducing the watery secretions associated with parasympathetic stimulation of the glands with little, if any, effect on the symptoms of congestion and sneezing. In general, these drugs have no systemic adverse effects, but can cause crusting and local irritation.Anticholinergic drugs are useful for the treatment of anterior rhinorrhea associated with allergic and nonallergic rhinitis.
Consensus definition of nonallergic rhinopathy, previously referred to as vasomotor rhinitis, nonallergic rhinitis, and/or idiopathic rhinitis
Michael A Kaliner, James N Baraniuk, Michael Benninger, Jonathan A Bernstein, Phil Lieberman, Eli O Meltzer, Robert M Naclerio, Russell A Settipane, Judith R Farrar
World Allergy Organization Journal , 2009, DOI: 10.1097/wox.0b013e3181a8e15a
Abstract:
Classification of nonallergic rhinitis syndromes with a focus on vasomotor rhinitis, proposed to be known henceforth as nonallergic rhinopathy
Michael A Kaliner
World Allergy Organization Journal , 2009, DOI: 10.1097/wox.0b013e3181a9d55b
Abstract:
Consensus Description of Inclusion and Exclusion Criteria for Clinical Studies of Nonallergic Rhinopathy (NAR), Previously Referred to as Vasomotor Rhinitis (VMR), Nonallergic Rhinitis, and/or Idiopathic Rhinitis
Michael A Kaliner, James N Baraniuk, Michael S Benninger, Jonathan A Bernstein, Phil Lieberman, Eli O Meltzer, Robert M Naclerio, Russell A Settipane, Judith R Farrar
World Allergy Organization Journal , 2009, DOI: 10.1097/wox.0b013e3181b2ff8a
Abstract:
TREATMENT OF VASOMOTOR RHINITIS WITH SHUNTHYADI TAILA NASYA  [PDF]
Khan Nisar Ali,Patil Sandeep Ramakrishna
International Journal of Research in Ayurveda and Pharmacy , 2013, DOI: 10.7897/2277-4343.04225
Abstract: Incidence of vasomotor rhinitis is increasing. It is hyper reactivity of vasomotor system of nasal cavity resulting in episodes of excessive sneezing, nasal block and watery rhinorrhoea. Treatment available in modern system of medicine gives temporary relief with side effects. In this study an attempt in made to establish an Ayurvedic treatment as a treatment of choice. 30 patients of vasomotor rhinitis are studied in two groups. Shunthyadi taila nasya is given to experimental group and Anu taila nasya is given to control group. Nasal block, nasal discharge and sneezing are kept as parameters of assessment. Results showed improvement in both groups but effect of treatment was better in experimental group.
Consensus review and definition of nonallergic rhinitis with a focus on vasomotor rhinitis, proposed to be known henceforth as nonallergic rhinopathy part 1. introduction
Michael A Kaliner, Judith R Farrar
World Allergy Organization Journal , 2009, DOI: 10.1097/wox.0b013e3181a8e146
Abstract:
Consensus Review and Definition of Nonallergic Rhinitis With a Focus on Vasomotor Rhinitis, Proposed to Be Known henceforth as Nonallergic Rhinopathy: Introduction to Part 2
Michael A Kaliner, Judith R Farrar
World Allergy Organization Journal , 2009, DOI: 10.1186/1939-4551-2-8-155
Abstract:
Nonallergic rhinitis, with a focus on vasomotor rhinitis clinical importance, differential diagnosis, and effective treatment recommendations
Mark D Scarupa, Michael A Kaliner
World Allergy Organization Journal , 2009, DOI: 10.1097/wao.0b013e318196ca1e
Abstract:
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