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TUMORS OF SALIVARY GLANDS  [cached]
Gaurav Solanki
International Journal of Pharmacological Research , 2012, DOI: 10.7439/ijpr.v1i2.355
Abstract: The glands are divided into major and minor salivary gland categories. The major salivary glands are the parotid, the submandibular, and the sublingual glands. The minor glands are dispersed throughout the upper aerodigestive submucosa. Salivary gland tumors are abnormal cells growing in the ducts that drain the salivary glands. Salivary glands tumors are uncommon and are subdivided into benign neoplasms, tumor-like conditions, and malignant neoplasms. They can be removed surgically or one can undergo radiation therapy for there cure. This article throws light on the types of salivary gland tumors, their signs and symptoms, treatment etc.
SALIVARY GLANDS - AN OVERVIEW  [cached]
Gaurav Solanki
International Journal of Biomedical and Advance Research , 2012, DOI: 10.7439/ijbar.v3i3.352
Abstract: The glands are divided into major and minor salivary gland categories. The major salivary glands are parotid, submandibular and sublingual glands. The minor glands are dispersed throughout the upper aero-digestive submucosa. Saliva is the watery substance produced in the mouths of humans and other animals. Saliva is a component of oral fluid. Human saliva is composed of 98% water, while the other 2% consists of other compounds such as electrolytes, mucus, antibacterial compounds and various enzymes. A review of some patents on salivary glands is also provided that summarizes the recent technical advancements taken place in this area.
Lymphoid lesions of salivary glands: Malignant and Benign
Ellis,Gary L.;
Medicina Oral, Patología Oral y Cirugía Bucal (Internet) , 2007,
Abstract: lesions of salivary glands with a prominent lymphoid component are a heterogeneous group of diseases that include benign reactive lesions and malignant neoplasms. occasionally, these pathologic entities present difficulties in the clinical and pathological diagnosis and prognosis. lymphoepithelial sialadenitis, hiv-associated salivary gland disease, chronic sclerosing sialadenitis, warthin tumor, and extranodal marginal zone b-cell lymphoma are examples of this pathology that are sometimes problematic to differentiate from one another. in this paper the author reviewed the main clinical, pathological and prognostic features of these lesions.
Salivary glands neoplasms  [cached]
Ogawa, Allex Itar,Takemoto, Lucio Eidy,Navarro, Paulo de Lima,Heshiki, Rosana Emiko
International Archives of Otorhinolaryngology , 2008,
Abstract: Introduction: Salivary glands neoplasms represent a rare and diverse group of tumors with different characteristics. To avoid complications and unnecessary procedures, the treatment depends on an accurate diagnosis. Objective: Review the literature emphasizing the latest advances in diagnosis and treatment. Method: An electronic research was performed on MEDLINE, OVID, PubMed and SciELO databases articles in a period between 1997 and 2007. Conclusion: The proper diagnosis of salivary glands neoplasms is complex, and the otorhinolaryngologist/head and neck surgeon needs to investigate the histological subtype to ensure ideal treatment. Frequently, diagnostic exams conflict, and careful case by case evaluation is required.
Imaging in major salivary gland diseases  [cached]
C. Botsios,P. Sfriso,C. Grava,P. Ostuni
Reumatismo , 2011, DOI: 10.4081/reumatismo.2001.235
Abstract: Most of the salivary glands diseases are characterized only by a few distinct clinical patterns. Medical history and clinical examination are still considered of great relevance. However, in order to obtaine a definite diagnosis, imaging techniques are required in most of the cases. Salivary glands ultrasonography (US) is the technique to be used as the first because US can easily differentiate calculosis, inflammatory diseases and tumors. Sonography is also frequently needed to perform needle aspiration or biopsy (FNAC). Sialography should be used essentially for assessing chronic sialoadenitis as well as Sj gren’s syndrome. At present, Magnetic Resonance sialography should be preferred because of the greater sensibility in diagnosing inflammatory diseases of the salivary glands. It allows to evaluate both intraglandular oedema and nodules, so that incannulation of the salivary duct is not required. Computer Tomography (CT) and Magnetic Resonance imaging (MR) are useful when neoplasm are suspected, particularly if deep areas of the gland, which cannot be visualized by US, are involved. Sequential scintigraphy is currently employed for assessing the functional status of all the 4 major salivary glands and evaluating the chronic evolution of glandular damage.
Histomorphology of Salivary Glands after Ligature and Reconstruction of Common Carotid Artery in Rabbits
Kaspars Stamers , Mara Pilmane , Laila Feldmane , Kalvis Pastars , Nonna Tomisheva , Andrejs Skagers
Acta Chirurgica Latviensis , 2009, DOI: 10.2478/v10163-010-0009-2
Abstract: Introduction. In occlusive diseases of carotid arteries may be involved salivary glands which play important role in oral and general homeostasis. Aim of the study. The purpose of this study was histomorphological evaluation of rabbit's salivary glands after regional reduction af arterial circulation and reconstruction of ligated common carotid arteries comparing with normal histological sight. Materials and methods. The experiments were authorized by the Animal Ethics Committee of the Latvian Food and Veterinary Service. 20 male Californian rabbits weighing approximately 3 kg were used. Under intravenous general anesthesia and local anesthesia the ligature of a. carotis communis dextra was done. After 28 days 10 rabbits were sacrificed and samples were taken from all major salivary glands and histological measured acinar dimensions and acinar epithelial cell. For rest 10 rabbits under the general anesthesia were performed revascularization of a. carotis communis dextra. After 28 days the rabbits were sacrificed with intrapulmonal injection of T61. The acini dimensions and acinar epithelial cell diameter in microns in all glands were measured except buccal glands were measured. Results. In ischemic conditions all glands react with decrease of acinar epithelial cell diameter and also diametr of functional unit of salivary gland. After revascularisation reestablishment of acini and secretory epithelial cells was observed. Conclusions. Rabbit's salivary glands have potential to recovery in diminished after ligation of ipsilateral common carotid artery size of acini and secretory epithelium after 4 week ischemia if the blood supply is reestabilished.
Transcriptomic Analysis of the Salivary Glands of an Invasive Whitefly  [PDF]
Yun-Lin Su, Jun-Min Li, Meng Li, Jun-Bo Luan, Xiao-Dong Ye, Xiao-Wei Wang, Shu-Sheng Liu
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0039303
Abstract: Background Some species of the whitefly Bemisia tabaci complex cause tremendous losses to crops worldwide through feeding directly and virus transmission indirectly. The primary salivary glands of whiteflies are critical for their feeding and virus transmission. However, partly due to their tiny size, research on whitefly salivary glands is limited and our knowledge on these glands is scarce. Methodology/Principal Findings We sequenced the transcriptome of the primary salivary glands of the Mediterranean species of B. tabaci complex using an effective cDNA amplification method in combination with short read sequencing (Illumina). In a single run, we obtained 13,615 unigenes. The quantity of the unigenes obtained from the salivary glands of the whitefly is at least four folds of the salivary gland genes from other plant-sucking insects. To reveal the functions of the primary glands, sequence similarity search and comparisons with the whole transcriptome of the whitefly were performed. The results demonstrated that the genes related to metabolism and transport were significantly enriched in the primary salivary glands. Furthermore, we found that a number of highly expressed genes in the salivary glands might be involved in secretory protein processing, secretion and virus transmission. To identify potential proteins of whitefly saliva, the translated unigenes were put into secretory protein prediction. Finally, 295 genes were predicted to encode secretory proteins and some of them might play important roles in whitefly feeding. Conclusions/Significance: The combined method of cDNA amplification, Illumina sequencing and de novo assembly is suitable for transcriptomic analysis of tiny organs in insects. Through analysis of the transcriptome, genomic features of the primary salivary glands were dissected and biologically important proteins, especially secreted proteins, were predicted. Our findings provide substantial sequence information for the primary salivary glands of whiteflies and will be the basis for future studies on whitefly-plant interactions and virus transmission.
Minor Salivary Glands Morphology in Xerostomia Patients
Liquidato,Bianca Maria; Barros,Mirna Duarte; Filho,Ivo Bussoloti; Pereira,Celina Siqueira Barbosa; Macéa,Maria Inêz Marcondes;
International Journal of Morphology , 2006, DOI: 10.4067/S0717-95022006000400031
Abstract: the minor salivary glands are found scattered throughout the oral mucosa, especially in the lips and soft palate mucosa. several factors can cause xerostomia, whereas the salivary glands histological characteristics are also considered as factors for defining the etiology. thus, the minor salivary glands biopsy represents an essential tool for attending the required diagnosis criterion in the classification of sj?gren's syndrome patients, since it does not present risk for the patient. the objective of this study is to determine the histological description of the minor salivary glands obtained from the biopsies of xerostomia patients and to classify the minor salivary gland histological aspect as the sj?gren's syndrome. forty laminas of xerostomia patients that were submitted to minor salivary glands biopsy at the santa casa de sao paulo stomatology ambulatory were retrospectively studied. the variation in the glands histological aspect was observed, from the normality up to the presence of inflammatory focus, replacing the conjunctive between acini and ducts, as well as the parenchyma. in 15 cases, the infiltrated inflammatory cells amounted to focus, that is to say, groups of at least 50 inflammatory cells around the acini or ducts, which is a characteristic aspect of the sj?gren's syndrome. therefore, the finding of at least one inflammatory focus of 4 mm2 of glandular tissue represents a set criterion, although, not the only one in order to classify this patient as having the sj?gren's syndrome
Mucoepidermoid Carcinoma of Minor Salivary Glands  [cached]
Tinoco, Paulo,Pereira, José Carlos Oliveira,Louren?o Filho, Rodolfo Caldas,Brito, Thiego Silveira Cajubá
International Archives of Otorhinolaryngology , 2011,
Abstract: Introduction: The Mucoepidermoid Carcinomas (MEC) represent about 5% of all tumors in the salivary glands. It is an aggressive lesion and must be considered as a diagnosis hypothesis in the oral mucosa proliferative lesions. The early diagnosis and the correct management of this neoplasm are key factors for the prognosis. Wide local resection and eventually postoperative radiotherapy is the choice treatment. Objective: To report the case of a patient with mucoepidermoid carcinoma of oral cavity, exteriorizing through the mouth and being submitted to surgical exeresis and radiotherapy that evolved to death on the fourth month from beginning of the treatment. Case Report: CT, 47 years old, white woman was forwarded to the ORL service of the HSJA after a critical bleeding episode in oral cavity. She reported the appearing of a mass with fast and expansive growth in a topography of canine fossa for +/- 06 months, associated to the loss of 10 kg. Patient dehydrated, pale with pediculated tumoration of +/- 06 cm, firm consistency, painless upon palpation and bleeding. Chronic alcoholic and smoker. Non-palpable cervical lymph nodes. Faced with the case we opted for a surgical resection of the tumor and the performance of histopathological exam that confirmed mucoepidermoid carcinoma of minor salivary glands. The patient was sent to the radiotherapy service; but she abandoned the treatment and evolved with death 4 months after. Final Comments: In this case, the fast and aggressive growth of the lesion, the size of the tumor and the abandonment of the proposed treatment was determinant for the patient's prognosis.
Mucocele of the anterior lingual salivary glands (Glands of Blandin and Nuhn)  [PDF]
Supriya Kheur,Rajiv S. Desai,Chintamani Kelkar A
Indian Journal of Dental Advancements , 2010,
Abstract: Mucoceles are known to occur in varying locations on the oral mucosal surfaces overlying accessory minor salivary glands. However they occur more frequently in certain locations . The lower lip is reported to be most commonly affected followed by the tongue. Mucoceles of the anterior lingual glands are rare and are hardly reported to occur in the pediatric age group. This article reports a case of mucocele of the glands of Blandin and Nuhn, in a 7- year- old girl.
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