oalib
Search Results: 1 - 10 of 100 matches for " "
All listed articles are free for downloading (OA Articles)
Page 1 /100
Display every page Item
Selective changes in the α-adrenoceptor-mediated contraction in the senescent rat urinary bladder  [PDF]
Tomomi Aita, Akira Ishihata, Akiko Yamada, Yumi Katano
Health (Health) , 2012, DOI: 10.4236/health.2012.429115
Abstract: The urinary bladder is innervated and functionally regulated by the autonomic nervous system. In order to elucidate the mechanism of functional changes in aged rat urinary bladder, we studied the influence of senescence on, 1) the α-adrenergic contractile response to phenylephrine in the urinary bladder body and trigone, 2) the muscarinic contractile response to carbachol in the body and trigone. The binding characteristics of [3H]quinuclidinyl benzilate (QNB) to muscarinic cholinoceptors were compared in young and aged bladder. Bladders from young (2 - 3 month-old) and aged (27 month-old) male Fischer 344 rats were isolated, cut into strips and mounted in the organ bath, then the developed tension was recorded. Histologically, the aged bladder did not show pathologic changes such as inflammation and hypertrophy. Carbachol-induced contraction in aged rat bladder was identical to that obtained in young rat. In the receptor binding assay, [3H]QNB maximal binding capacity and Kd value were not significantly changed in aged bladder. In contrast, a selective α-adrenergic agonist phenylephrine, elicited greater contractions both in the aged body and trigone than those in young rats. The augmentation of α-adrenoceptor-mediated contractions in aged bladder may induce urinary dysfunction such as voiding difficulty.
Human Urinary Bladder Strip Relaxation by the β-Adrenoceptor Agonist Isoprenaline: Methodological Considerations and Effects of Gender and Age  [PDF]
Martin C. Michel
Frontiers in Pharmacology , 2011, DOI: 10.3389/fphar.2011.00011
Abstract: The present study was primarily designed to explore various methodological aspects related to organ bath experiments evaluating human detrusor relaxation by the β-adrenoceptor agonist isoprenaline. Data are based upon a series of 30 consecutive patients, and this cohort was also used to explore possible effects of gender and age. KCl-induced contraction was related to strip length but not weight or cross-sectional area, indicating that the former is most suitable for data normalization. Storage of detrusor strips in cold buffer for up to 2 days did not affect contractile responses to KCl or efficacy of isoprenaline to cause relaxation but significantly affected the isoprenaline potency. No such alterations were observed with up to 1 day of cold storage. The type (KCl vs. passive tension) or strength of contractile stimulus had only minor effects on isoprenaline responses although these differences reached statistical significance in some cases. Similarly, gender and age had only minor if any effects on KCl-induced contraction or isoprenaline-induced relaxation, but the current data are too limited for robust conclusions. In summary we have evaluated experimental conditions for the testing of human detrusor strip contraction and relaxation which should be useful for future larger studies.
Lymphoma of the Urinary Bladder  [PDF]
Anthony Kodzo-Grey Venyo
Advances in Urology , 2014, DOI: 10.1155/2014/327917
Abstract: Background. Lymphoma of the urinary bladder (LUB) is rare. Aims. To review the literature on LUB. Methods. Various internet databases were used. Results. LUB can be either primary or secondary. The tumour has female predominance; most cases occur in middle-age women. Secondary LUB occurs in 10% to 25% of leukemias/lymphomas and in advanced-stage systemic lymphoma. Less than 100 cases have been reported. MALT typically affects adults older than 60 years; 75% are female. Diffuse large B-cell lymphoma is also common and may arise from transformation of MALT. LUB presents with haematuria, dysuria, urinary frequency, nocturia, and abdominal or back pain. Macroscopic examination of LUBs show large discrete tumours centred in the dome or lateral walls of the bladder. Positive staining of LUB varies by the subtype of lymphoma; B-cell lymphomas are CD20 positive. MALT lymphoma is positively stained for CD20, CD19, and FMC7 and negatively stained for CD5, CD10, and CD11c. LUB stains negatively with Pan-keratin, vimentin, CK20, and CK7. MALT lymphoma exhibits t(11; 18)(q21: 21). Radiotherapy is an effective treatment for the MALT type of LUB with no recurrence. Conclusions. LUB is diagnosed by its characteristic morphology and immunohistochemical characteristics. Radiotherapy is a useful treatment. 1. Introduction Lymphoma of the urinary bladder is an uncommon lesion; and its diagnostic features may not be well known by the unaccustomed practitioner. The ensuing document contains a review of the literature on lymphoma of the urinary bladder. 2. Methods The key words used for the search were Lymphoma of bladder; lymphoma of urinary bladder; vesical lymphoma. Documentations from 46 sources were found which had discussed various aspects relevant to lymphoma of the urinary bladder and information from these 46 sources were used to write the literature review. 3. Literature Review 3.1. Overview Definition. Lymphoma of the urinary bladder can be either (a) primary lymphoma of the urinary bladder and this is a rare lymphoma originating in the urinary bladder with no known lymphoma elsewhere or (b) secondary lymphoma of the urinary bladder and this is much more common, and this secondary lymphoma is associated with a primary lymphoma originating in an extra vesical site [1]. Epidemiology. Lymphomas of the urinary bladder have a female predominance, and most cases of lymphoma of the urinary bladder occur in middle-age women [1]. Secondary involvement of the urinary bladder occurs in 10% to 25% of leukemias/lymphomas and they occur in advanced-stage systemic lymphoma [1].
Primary amyloidosis of urinary bladder
Basri ?ak?ro?lu,Lora Ate?,Ramazan G?zükü?ük,Mustafa Gü?lü
Dicle Medical Journal , 2013,
Abstract: Primary amyloidosis of the bladder is a rare pathologicalcondition, which the etiology is unknown. The signsand symptoms suggests bladder tumor. In some patients,lower urinary tract symptoms such as lower abdominalpain, frequent urination, dysuria and complaints of grosspainless hematuria occur. In this study, a case of primarylocalized amyloidosis of the bladder in a 66 years oldfemale who had gross painless hematuria as the initialsymptom is described.Key words: Amyloidosis, bladder, hematuria
Verrucous Carcinoma of Urinary Bladder
Ufuk USTA,Bulent MIZRAK,Iclal GURSES
Trakya Universitesi Tip Fakultesi Dergisi , 2006,
Abstract: Verrucous carcinoma is a very rare entity in the urinary bladder, and it is usually associated with Condyloma accuminatum and schistosomiasis. Though chronic irritation is accepted as a common etiological factor in few rare cases, bladder stone has not been demonstrated among irritative etiologic agents. Verrucous carcinoma in the bladder of a man of 54 years, who underwent three surgical interventions in the last 20 years because of bladder stone, is presented. The histopathological diagnosis of the specimen from the third operation was verrucous carcinoma of the bladder. Recently the fourth operation; a transurethral resection was performed, as the verrucous carcinoma relapsed.
Surprises in the urinary bladder
Bhushan Wani,Suhas Jajoo,Navinchandra Wani,et al
Open Access Surgery , 2010,
Abstract: Bhushan Wani1, Suhas Jajoo1, Navinchandra Wani2, Anil Bhole11Department of Surgery, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, India; 2Department of Surgery, Annasaheb Chudaman Patil Memorial Medical College, Dhule, IndiaAbstract: Foreign bodies of the urinary bladder may occur by self insertion, iatrogenic means or migration from the neighbouring organs. The variety of objects found self-inserted is impressive. The patient usually presents with dysuria, poor urinary stream or retention, bloody or purulent urethral discharge, ascending urinary tract infection, urgency, and/or pelvic pain. Management should be tailored according to the nature and dimensions of the foreign body. In the following paper, we report three cases with different presentations that were managed successfully.Keywords: urinary, bladder, foreign bodies
Surprises in the urinary bladder
Bhushan Wani, Suhas Jajoo, Navinchandra Wani, et al
Open Access Surgery , 2010, DOI: http://dx.doi.org/10.2147/OAS.S9450
Abstract: rprises in the urinary bladder Case report (4417) Total Article Views Authors: Bhushan Wani, Suhas Jajoo, Navinchandra Wani, et al Published Date April 2010 Volume 2010:3 Pages 23 - 26 DOI: http://dx.doi.org/10.2147/OAS.S9450 Bhushan Wani1, Suhas Jajoo1, Navinchandra Wani2, Anil Bhole1 1Department of Surgery, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, India; 2Department of Surgery, Annasaheb Chudaman Patil Memorial Medical College, Dhule, India Abstract: Foreign bodies of the urinary bladder may occur by self insertion, iatrogenic means or migration from the neighbouring organs. The variety of objects found self-inserted is impressive. The patient usually presents with dysuria, poor urinary stream or retention, bloody or purulent urethral discharge, ascending urinary tract infection, urgency, and/or pelvic pain. Management should be tailored according to the nature and dimensions of the foreign body. In the following paper, we report three cases with different presentations that were managed successfully.
URINARY BLADDER GOSSIPYBOMA
MUHAMMAD IJAZ
The Professional Medical Journal , 2006,
Abstract: A 57 years old gentleman was brought with history of recurrent UTI (Urinary tract infection) of 01 yearduration. Following transvesical prostatectomy. UTI could not be controlled after using appropriate antibiotics. Allrelevant investigations were performed. His cystoscopic examination revealed retained gauze piece (12 inches ) inurinary bladder, which was retrieved.
Sarcomatoid Carcinoma of the Urinary Bladder  [PDF]
Kenji Shimodaira, Isao Kuroda, Naohiro Kamoda, Takuya Ishida, Teiichiro Aoyagi, Masaaki Tachibana
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.34044
Abstract:

The patient was a 62-year-old female with bladder carcinoma. TUR-BT was performed in March 2010, and the pathological finding was UC, G2 > G1, pTa. However, the cancer recurred in the urinary bladder 3 months after TUR-BT. Radical cystectomy was performed, and the disease was considered to have been cured, but metastasis developed in the skin, lung, liver, and bone several months after surgery. Chemotherapy was ineffective, and the patient died. On pathological examination at the time of radical cystectomy, the lesion was sarcomatoid carcinoma of the urinary bladder. Although the prognosis associated with this carcinoma is known to be poor, the possibility of underestimation on preoperative staging cannot be ruled out from the cause, in addition to the insufficiency of the current therapeutic strategy.

Bladder Dysfunction and Urinary Incontinence
F. faizi
Iranian Journal of Radiology , 2009,
Abstract: "nIn the name of God. Dear colleagues, ladies and gentlemen, it is a great honor to be here. Bladder dysfunction is serious enough to seek serious help. If you may know I am working in a private clinic which it is impossible to follow the patients so this lecture is based on unusual and rare cases who came to me. Bladder dysfunction (BD) is common among 30% of young and old people who are suffering from it, however it is more common in old ages. According to a research, women are more involved as in men which prostate has a role is more common. The usual cases were: "n1. A young girl, aged 20, who had to wake up five times during the night to micturate. "n2. Also a lady said when I roll in bed I wet myself. "n3. A young lady who always had to use a pad. "n4. A man said I can’t use underground. "n5. I cannot go out since I have to micturate every hour. "n6. One said I have to wake up every hour at night. "n7. Young people say we have to micturate 3-4 times at night. "n8. A young man said as soon as I feel to micturate I empty my bladder before I’ve reached the WC and I wet myself to the ankle, how could I have a job? "n9. Some women wet themselves when they cough. "nIn order to know and diagnosis, the physiology of bladder function must be known. "nThe bladder is divided into two parts: "nThe Dom, which is innervated by Beta-Adrenergic. It relaxes the bladder in order to comply the urine. "nFrom the orifice of the urether and posterior ridge of the trigon to the bladder neck or internal sphincter. The prostatic urethra plays a major role in conti- nence. It has two parts, "n1: From the bladder neck to V.M. this is enclaved by extension of detrusor muscles like a sleeve. These muscles contract during ejaculation to prevent retrograde ejaculation. "nDistal urethra from V.M. to the external sphincter which is covered by voluntary muscles. "nThe internal pressure of the urethra is higher than the bladder. If the pressure of the bladder rises, the internal pressure of the urethra should also increase. In women, the internal pressure of the urethra is short, and even if it has poorly developed they wet themselves when they cough. "nThe causes of BD: "nAs you see there are 17 causes, which 11 are related to the bladder. The bladder is responsible for retaining the urine and voiding. "nPathophysiology: "nThe bladder and sphincter should work in a coordinated manner: "nDuring the course of a day, an average person will void approximately 4-8 times. The urinary bladder is in storage mode for most of the day, allowing an individual to engage in more important ac
Page 1 /100
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.